IT201600103956A1 - Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma - Google Patents
Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucomaInfo
- Publication number
- IT201600103956A1 IT201600103956A1 IT102016000103956A IT201600103956A IT201600103956A1 IT 201600103956 A1 IT201600103956 A1 IT 201600103956A1 IT 102016000103956 A IT102016000103956 A IT 102016000103956A IT 201600103956 A IT201600103956 A IT 201600103956A IT 201600103956 A1 IT201600103956 A1 IT 201600103956A1
- Authority
- IT
- Italy
- Prior art keywords
- cyticoline
- liposomas
- vehiculated
- glaucoma
- treatment
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102016000103956A IT201600103956A1 (it) | 2016-10-17 | 2016-10-17 | Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma |
| ES17811373T ES2987910T3 (es) | 2016-10-17 | 2017-10-16 | Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma |
| EP17811373.4A EP3525758B1 (en) | 2016-10-17 | 2017-10-16 | Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma |
| TNP/2019/000112A TN2019000112A1 (en) | 2016-10-17 | 2017-10-16 | Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma |
| PCT/IB2017/056400 WO2018073720A1 (en) | 2016-10-17 | 2017-10-16 | Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma |
| US16/342,261 US10576039B2 (en) | 2016-10-17 | 2017-10-16 | Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma |
| JP2019520647A JP7042262B2 (ja) | 2016-10-17 | 2017-10-16 | 緑内障の治療のための、リポソームによって担持されるシチコリンを含む眼科用処方 |
| EA201990752A EA201990752A1 (ru) | 2016-10-17 | 2017-10-16 | Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы |
| MX2019004463A MX388927B (es) | 2016-10-17 | 2017-10-16 | Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102016000103956A IT201600103956A1 (it) | 2016-10-17 | 2016-10-17 | Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT201600103956A1 true IT201600103956A1 (it) | 2018-04-17 |
Family
ID=58010202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT102016000103956A IT201600103956A1 (it) | 2016-10-17 | 2016-10-17 | Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10576039B2 (enExample) |
| EP (1) | EP3525758B1 (enExample) |
| JP (1) | JP7042262B2 (enExample) |
| EA (1) | EA201990752A1 (enExample) |
| ES (1) | ES2987910T3 (enExample) |
| IT (1) | IT201600103956A1 (enExample) |
| MX (1) | MX388927B (enExample) |
| TN (1) | TN2019000112A1 (enExample) |
| WO (1) | WO2018073720A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3412276B1 (de) | 2017-06-09 | 2025-11-19 | Omnivision GmbH | Zusammensetzung zur behandlung des trockenen auges |
| IT201800005309A1 (it) * | 2018-05-11 | 2019-11-11 | Composizione ad attivita’ antimicrobica | |
| CN110559261A (zh) * | 2018-06-06 | 2019-12-13 | 常州药物研究所有限公司 | 含有纳米交联透明质酸的脂质体微乳及其制备方法和应用 |
| CN111840220B (zh) * | 2020-08-19 | 2022-09-30 | 开封康诺药业有限公司 | 一种胞磷胆碱钠注射液及其制备方法 |
| MX2023013266A (es) * | 2021-05-10 | 2023-12-15 | Omikron Italia S R L | Solucion oral basada en citicolina y nicotinamida para usar en el tratamiento del glaucoma. |
| WO2025037323A1 (en) * | 2023-08-12 | 2025-02-20 | Pavan Kumar Kothapuvari | Pharmaceutical compositions for treatment of dry eye disease and associated disorders |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0114577A1 (en) * | 1983-01-21 | 1984-08-01 | MAGIS FARMACEUTICI S.p.A. | New pharmaceutical composition |
| WO2010092597A2 (en) * | 2009-02-11 | 2010-08-19 | Lyka Labs Limited | Liposomal citicoline injection |
| WO2011101802A1 (en) * | 2010-02-22 | 2011-08-25 | Omikron Italia S.R.L. | Citicoline for the treatment of glaucoma and ocular hypertension |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001292287A1 (en) * | 2000-10-26 | 2002-05-06 | Senju Pharmaceutical Co. Ltd. | Drug composition comprising dipeptydyl aldehyde derivative |
| FR2961694B1 (fr) | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
| SG187770A1 (en) | 2010-08-12 | 2013-03-28 | Univ Nanyang Tech | A liposomal formulation for ocular drug delivery |
| CN102078299B (zh) * | 2011-01-04 | 2012-09-26 | 海南美大制药有限公司 | 胞磷胆碱钠脂质体固体制剂 |
-
2016
- 2016-10-17 IT IT102016000103956A patent/IT201600103956A1/it unknown
-
2017
- 2017-10-16 ES ES17811373T patent/ES2987910T3/es active Active
- 2017-10-16 EP EP17811373.4A patent/EP3525758B1/en active Active
- 2017-10-16 MX MX2019004463A patent/MX388927B/es unknown
- 2017-10-16 US US16/342,261 patent/US10576039B2/en active Active
- 2017-10-16 JP JP2019520647A patent/JP7042262B2/ja active Active
- 2017-10-16 WO PCT/IB2017/056400 patent/WO2018073720A1/en not_active Ceased
- 2017-10-16 EA EA201990752A patent/EA201990752A1/ru unknown
- 2017-10-16 TN TNP/2019/000112A patent/TN2019000112A1/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0114577A1 (en) * | 1983-01-21 | 1984-08-01 | MAGIS FARMACEUTICI S.p.A. | New pharmaceutical composition |
| WO2010092597A2 (en) * | 2009-02-11 | 2010-08-19 | Lyka Labs Limited | Liposomal citicoline injection |
| WO2011101802A1 (en) * | 2010-02-22 | 2011-08-25 | Omikron Italia S.R.L. | Citicoline for the treatment of glaucoma and ocular hypertension |
Non-Patent Citations (1)
| Title |
|---|
| PARISI V ET AL: "Evidence of the neuroprotective role of citicoline in glaucoma patients", 1 January 2008, GLAUCOMA: AN OPEN WINDOW TO NEURODEGENERATION AND NEUROPROTECTION; [PROGRESS IN BRAIN RESEARCH], AMSTERDAM [U.A.] : ELSEVIER, NL, PAGE(S) 541 - 554, ISBN: 978-0-444-53256-5, XP008127684 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3525758A1 (en) | 2019-08-21 |
| WO2018073720A1 (en) | 2018-04-26 |
| JP7042262B2 (ja) | 2022-03-25 |
| US20190321292A1 (en) | 2019-10-24 |
| MX2019004463A (es) | 2019-09-11 |
| JP2019530729A (ja) | 2019-10-24 |
| EP3525758C0 (en) | 2024-05-22 |
| TN2019000112A1 (en) | 2020-10-05 |
| MX388927B (es) | 2025-03-20 |
| ES2987910T3 (es) | 2024-11-18 |
| US10576039B2 (en) | 2020-03-03 |
| EP3525758B1 (en) | 2024-05-22 |
| EA201990752A1 (ru) | 2019-09-30 |
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