IT201600103956A1 - Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma - Google Patents

Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma

Info

Publication number
IT201600103956A1
IT201600103956A1 IT102016000103956A IT201600103956A IT201600103956A1 IT 201600103956 A1 IT201600103956 A1 IT 201600103956A1 IT 102016000103956 A IT102016000103956 A IT 102016000103956A IT 201600103956 A IT201600103956 A IT 201600103956A IT 201600103956 A1 IT201600103956 A1 IT 201600103956A1
Authority
IT
Italy
Prior art keywords
cyticoline
liposomas
vehiculated
glaucoma
treatment
Prior art date
Application number
IT102016000103956A
Other languages
English (en)
Inventor
Cristiano Virno
Marco Malizia
Original Assignee
Omikron Italia S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omikron Italia S R L filed Critical Omikron Italia S R L
Priority to IT102016000103956A priority Critical patent/IT201600103956A1/it
Priority to EP17811373.4A priority patent/EP3525758B1/en
Priority to EA201990752A priority patent/EA201990752A1/ru
Priority to JP2019520647A priority patent/JP7042262B2/ja
Priority to US16/342,261 priority patent/US10576039B2/en
Priority to MX2019004463A priority patent/MX2019004463A/es
Priority to TNP/2019/000112A priority patent/TN2019000112A1/en
Priority to PCT/IB2017/056400 priority patent/WO2018073720A1/en
Publication of IT201600103956A1 publication Critical patent/IT201600103956A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT102016000103956A 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma IT201600103956A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT102016000103956A IT201600103956A1 (it) 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma
EP17811373.4A EP3525758B1 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma
EA201990752A EA201990752A1 (ru) 2016-10-17 2017-10-16 Офтальмологический состав, содержащий цитиколин, переносимый липосомой, для лечения глаукомы
JP2019520647A JP7042262B2 (ja) 2016-10-17 2017-10-16 緑内障の治療のための、リポソームによって担持されるシチコリンを含む眼科用処方
US16/342,261 US10576039B2 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma
MX2019004463A MX2019004463A (es) 2016-10-17 2017-10-16 Formulacion oftalmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma.
TNP/2019/000112A TN2019000112A1 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma
PCT/IB2017/056400 WO2018073720A1 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000103956A IT201600103956A1 (it) 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma

Publications (1)

Publication Number Publication Date
IT201600103956A1 true IT201600103956A1 (it) 2018-04-17

Family

ID=58010202

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102016000103956A IT201600103956A1 (it) 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma

Country Status (8)

Country Link
US (1) US10576039B2 (it)
EP (1) EP3525758B1 (it)
JP (1) JP7042262B2 (it)
EA (1) EA201990752A1 (it)
IT (1) IT201600103956A1 (it)
MX (1) MX2019004463A (it)
TN (1) TN2019000112A1 (it)
WO (1) WO2018073720A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3412276A3 (de) 2017-06-09 2019-07-17 Omnivision GmbH Zusammensetzung zur behandlung des trockenen auges
IT201800005309A1 (it) * 2018-05-11 2019-11-11 Composizione ad attivita’ antimicrobica
CN110559261A (zh) * 2018-06-06 2019-12-13 常州药物研究所有限公司 含有纳米交联透明质酸的脂质体微乳及其制备方法和应用
CN111840220B (zh) * 2020-08-19 2022-09-30 开封康诺药业有限公司 一种胞磷胆碱钠注射液及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
WO2010092597A2 (en) * 2009-02-11 2010-08-19 Lyka Labs Limited Liposomal citicoline injection
WO2011101802A1 (en) * 2010-02-22 2011-08-25 Omikron Italia S.R.L. Citicoline for the treatment of glaucoma and ocular hypertension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002034252A (ja) * 2000-07-18 2002-01-31 Sony Corp スイッチング電源回路
FR2961694B1 (fr) * 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
US10272040B2 (en) * 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
CN102078299B (zh) * 2011-01-04 2012-09-26 海南美大制药有限公司 胞磷胆碱钠脂质体固体制剂

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
WO2010092597A2 (en) * 2009-02-11 2010-08-19 Lyka Labs Limited Liposomal citicoline injection
WO2011101802A1 (en) * 2010-02-22 2011-08-25 Omikron Italia S.R.L. Citicoline for the treatment of glaucoma and ocular hypertension

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PARISI V ET AL: "Evidence of the neuroprotective role of citicoline in glaucoma patients", 1 January 2008, GLAUCOMA: AN OPEN WINDOW TO NEURODEGENERATION AND NEUROPROTECTION; [PROGRESS IN BRAIN RESEARCH], AMSTERDAM [U.A.] : ELSEVIER, NL, PAGE(S) 541 - 554, ISBN: 978-0-444-53256-5, XP008127684 *

Also Published As

Publication number Publication date
WO2018073720A1 (en) 2018-04-26
JP7042262B2 (ja) 2022-03-25
JP2019530729A (ja) 2019-10-24
TN2019000112A1 (en) 2020-10-05
EP3525758A1 (en) 2019-08-21
EP3525758C0 (en) 2024-05-22
EA201990752A1 (ru) 2019-09-30
MX2019004463A (es) 2019-09-11
EP3525758B1 (en) 2024-05-22
US10576039B2 (en) 2020-03-03
US20190321292A1 (en) 2019-10-24

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