ES2987910T3 - Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma - Google Patents

Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma Download PDF

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Publication number
ES2987910T3
ES2987910T3 ES17811373T ES17811373T ES2987910T3 ES 2987910 T3 ES2987910 T3 ES 2987910T3 ES 17811373 T ES17811373 T ES 17811373T ES 17811373 T ES17811373 T ES 17811373T ES 2987910 T3 ES2987910 T3 ES 2987910T3
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ES
Spain
Prior art keywords
citicoline
liposomes
glaucoma
treatment
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17811373T
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English (en)
Spanish (es)
Inventor
Cristiano Virno
Marco Malizia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OMIKRON ITALIA Srl
Original Assignee
OMIKRON ITALIA Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OMIKRON ITALIA Srl filed Critical OMIKRON ITALIA Srl
Application granted granted Critical
Publication of ES2987910T3 publication Critical patent/ES2987910T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES17811373T 2016-10-17 2017-10-16 Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma Active ES2987910T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102016000103956A IT201600103956A1 (it) 2016-10-17 2016-10-17 Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma
PCT/IB2017/056400 WO2018073720A1 (en) 2016-10-17 2017-10-16 Ophthalmic formulation comprising citicoline carried by liposome for the treatment of glaucoma

Publications (1)

Publication Number Publication Date
ES2987910T3 true ES2987910T3 (es) 2024-11-18

Family

ID=58010202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17811373T Active ES2987910T3 (es) 2016-10-17 2017-10-16 Formulación oftálmica que comprende citicolina transportada por liposomas para el tratamiento del glaucoma

Country Status (9)

Country Link
US (1) US10576039B2 (enExample)
EP (1) EP3525758B1 (enExample)
JP (1) JP7042262B2 (enExample)
EA (1) EA201990752A1 (enExample)
ES (1) ES2987910T3 (enExample)
IT (1) IT201600103956A1 (enExample)
MX (1) MX388927B (enExample)
TN (1) TN2019000112A1 (enExample)
WO (1) WO2018073720A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3412276B1 (de) 2017-06-09 2025-11-19 Omnivision GmbH Zusammensetzung zur behandlung des trockenen auges
IT201800005309A1 (it) * 2018-05-11 2019-11-11 Composizione ad attivita’ antimicrobica
CN110559261A (zh) * 2018-06-06 2019-12-13 常州药物研究所有限公司 含有纳米交联透明质酸的脂质体微乳及其制备方法和应用
CN111840220B (zh) * 2020-08-19 2022-09-30 开封康诺药业有限公司 一种胞磷胆碱钠注射液及其制备方法
MX2023013266A (es) * 2021-05-10 2023-12-15 Omikron Italia S R L Solucion oral basada en citicolina y nicotinamida para usar en el tratamiento del glaucoma.
WO2025037323A1 (en) * 2023-08-12 2025-02-20 Pavan Kumar Kothapuvari Pharmaceutical compositions for treatment of dry eye disease and associated disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
AU2001292287A1 (en) * 2000-10-26 2002-05-06 Senju Pharmaceutical Co. Ltd. Drug composition comprising dipeptydyl aldehyde derivative
JP2012517421A (ja) 2009-02-11 2012-08-02 ライカ ラブズ リミテッド リポソームシチコリン注射薬
IT1398378B1 (it) * 2010-02-22 2013-02-22 Omikron Italia S R L Citicolina per il trattamento del glaucoma e dell'ipertensione oculare.
FR2961694B1 (fr) 2010-06-29 2013-01-25 Thea Lab Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur
SG187770A1 (en) 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
CN102078299B (zh) * 2011-01-04 2012-09-26 海南美大制药有限公司 胞磷胆碱钠脂质体固体制剂

Also Published As

Publication number Publication date
IT201600103956A1 (it) 2018-04-17
EP3525758A1 (en) 2019-08-21
WO2018073720A1 (en) 2018-04-26
JP7042262B2 (ja) 2022-03-25
US20190321292A1 (en) 2019-10-24
MX2019004463A (es) 2019-09-11
JP2019530729A (ja) 2019-10-24
EP3525758C0 (en) 2024-05-22
TN2019000112A1 (en) 2020-10-05
MX388927B (es) 2025-03-20
US10576039B2 (en) 2020-03-03
EP3525758B1 (en) 2024-05-22
EA201990752A1 (ru) 2019-09-30

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