JP2019529572A5 - - Google Patents
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- JP2019529572A5 JP2019529572A5 JP2019538583A JP2019538583A JP2019529572A5 JP 2019529572 A5 JP2019529572 A5 JP 2019529572A5 JP 2019538583 A JP2019538583 A JP 2019538583A JP 2019538583 A JP2019538583 A JP 2019538583A JP 2019529572 A5 JP2019529572 A5 JP 2019529572A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- treatment process
- once
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 238000000034 method Methods 0.000 claims 15
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims 10
- 208000037009 Vaginitis bacterial Diseases 0.000 claims 10
- 238000011282 treatment Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 9
- 238000011221 initial treatment Methods 0.000 claims 6
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 239000002562 thickening agent Substances 0.000 claims 4
- 229920001661 Chitosan Polymers 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 241000287436 Turdus merula Species 0.000 claims 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 2
- 239000000783 alginic acid Substances 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 229960001126 alginic acid Drugs 0.000 claims 2
- 150000004781 alginic acids Chemical class 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 229940071676 hydroxypropylcellulose Drugs 0.000 claims 2
- -1 polycarbofyl Polymers 0.000 claims 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000000230 xanthan gum Substances 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- 235000010493 xanthan gum Nutrition 0.000 claims 2
- 229940082509 xanthan gum Drugs 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022124559A JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404061P | 2016-10-04 | 2016-10-04 | |
| US62/404,061 | 2016-10-04 | ||
| PCT/US2017/054943 WO2018067568A1 (en) | 2016-10-04 | 2017-10-03 | Method of treatment and prevention of bacterial vaginosis |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124559A Division JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Division JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019529572A JP2019529572A (ja) | 2019-10-17 |
| JP2019529572A5 true JP2019529572A5 (https=) | 2020-11-05 |
Family
ID=61831547
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019538583A Pending JP2019529572A (ja) | 2016-10-04 | 2017-10-03 | 細菌性膣炎の治療および予防方法 |
| JP2022124559A Pending JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Pending JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A Pending JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124559A Pending JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Pending JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A Pending JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11419835B2 (https=) |
| EP (1) | EP3522879A4 (https=) |
| JP (4) | JP2019529572A (https=) |
| CN (1) | CN110225750A (https=) |
| AU (1) | AU2017338748A1 (https=) |
| WO (1) | WO2018067568A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693812A (zh) | 2012-06-13 | 2020-01-17 | 伊沃菲姆股份有限公司 | 用于增强避孕杀微生物剂有效性的组合物和方法 |
| WO2020076805A1 (en) * | 2018-10-09 | 2020-04-16 | Crapaud Bio, Inc. | METHODS OF MAKING AND USING pH MODULATING COMPOSITIONS IN THE REPRODUCTIVE SYSTEM |
| JP7706226B2 (ja) * | 2020-06-26 | 2025-07-11 | 小林製薬株式会社 | 粘膜洗浄用組成物 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1213323B (it) | 1986-08-07 | 1989-12-20 | Crinos Industria Farmaco | Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida |
| US4999342A (en) | 1988-08-16 | 1991-03-12 | Ortho Pharmaceutical Corporation | Long lasting contraceptive suppository composition and methods of use |
| JP3202365B2 (ja) | 1992-12-04 | 2001-08-27 | 株式会社紀文フードケミファ | オリゴマンヌロン酸を重合度によって分離する方法 |
| US5592949A (en) | 1994-06-29 | 1997-01-14 | Moench; Thomas R. | Device for acidic buffering and method for inactivation of pathogens |
| US5667492A (en) | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
| FR2728464B1 (fr) | 1994-12-22 | 1997-04-30 | Innothera Lab Sa | Forme galenique unitaire, son procede d'obtention et ses utilisations |
| US6093394A (en) | 1997-04-11 | 2000-07-25 | Gynelogix, Inc. | Vaginal lactobacillus medicant |
| ES2165139T3 (es) * | 1998-04-30 | 2002-03-01 | Vesely Renata Maria Cavaliere | Composiciones farmaceuticas que contienen lactobacillus brevis y lactobacillus salivarius para el tratamiento de infecciones vaginales. |
| AU1661901A (en) | 1999-11-24 | 2001-06-04 | Cargill Dow Llc | Improved lactic acid processing; methods; arrangements; and, products |
| PL202918B1 (pl) * | 2000-03-07 | 2009-08-31 | Rush Presbyterian St Luke | Przeciwbakteryjna i antykoncepcyjna kompozycja oraz jej zastosowanie |
| JP2009102407A (ja) | 2001-03-08 | 2009-05-14 | Rohto Pharmaceut Co Ltd | Ｇリッチなアルギン酸含有組成物 |
| US20020177624A1 (en) | 2001-03-16 | 2002-11-28 | Calvin Hanna | Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis |
| ITMI20010913A1 (it) | 2001-05-04 | 2002-11-04 | Univ Pavia | Composizioni a rilascio controllato di acido lattico a livello vaginale |
| WO2002100351A2 (en) | 2001-06-11 | 2002-12-19 | Merck & Co., Inc. | A method for treating inflammatory diseases by administering a ppar-delta agonist |
| US7291477B2 (en) * | 2001-07-03 | 2007-11-06 | Xenotope Diagnostics, Inc. | Method and device for trichomonas detection |
| US20060105008A1 (en) * | 2002-03-28 | 2006-05-18 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
| US20130150810A1 (en) | 2002-04-30 | 2013-06-13 | The Population Council, Inc. | Intravaginal ring for the delivery of unique combinations of antimicrobial compositions |
| WO2004011032A1 (ja) | 2002-07-26 | 2004-02-05 | Mikasa Seiyaku Co., Ltd. | 外用剤 |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| ES2752773T3 (es) * | 2003-06-13 | 2020-04-06 | Idh Holding Aps | Tratamiento de los síntomas asociados a la vaginosis bacteriana |
| US20050272700A1 (en) | 2004-05-10 | 2005-12-08 | Servet Buyuktimkin | Topical treatment and prevention of human papilloma virus (HPV) infection |
| RU2257197C1 (ru) | 2004-05-12 | 2005-07-27 | Дулькис Мария Дмитриевна | Вагинальные суппозитории, обладающие контрацептивным действием |
| UA93354C2 (ru) | 2004-07-09 | 2011-02-10 | Гилиад Сайенсиз, Инк. | Местный противовирусный препарат |
| US20100069323A1 (en) | 2006-11-10 | 2010-03-18 | Rohto Pharmaceutical Co., Ltd. | Composition for application to skin or mucosa |
| US7659259B2 (en) | 2006-12-21 | 2010-02-09 | Bausch & Lomb Incorporated | Method of treating inflammation of the eye |
| MX2009010445A (es) | 2007-03-30 | 2010-01-29 | Laccure Ab | Uso de oligomeros de acido lactico en el tratamiento de trastornos ginecologicos. |
| AU2008256689A1 (en) | 2007-05-24 | 2008-12-04 | New York Blood Center Inc. | Rapidly dispersible vaginal tablet that provides a bioadhesive gel |
| TW200927141A (en) | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| KR20110003534A (ko) | 2008-04-16 | 2011-01-12 | 시플라 리미티드 | 항진균제 및 항바이러스제를 포함하는 국소 조합물 |
| WO2009155118A1 (en) | 2008-05-30 | 2009-12-23 | Reprotect, Inc. | Compositions and methods for inactivation of pathogens at genital tract surfaces |
| EP2130531A1 (en) | 2008-06-04 | 2009-12-09 | Rolf Kullgren AB | Vaginal suppository comprising lactic acid |
| US20120070476A1 (en) * | 2009-05-29 | 2012-03-22 | Moench Thomas R | Compositions and Methods for Inactivation of Pathogens at Genital Tract Surfaces |
| EP2440560A1 (en) | 2009-06-10 | 2012-04-18 | Ultimorphix Technologies B.v. | The succinate of tenofovir disoproxil |
| JP6154803B2 (ja) | 2011-05-02 | 2017-06-28 | アデア ファーマスーティカルズ，インコーポレイテッド | 膣投与のための迅速溶解性錠剤組成物 |
| AU2012275292B2 (en) | 2011-06-28 | 2015-11-12 | Chemo Research, S.L. | High dosage mucoadhesive metronidazole aqueous-based gel formulations their use to treat bacterial vaginosis |
| JP2015510914A (ja) * | 2012-03-19 | 2015-04-13 | ドクトア・アウグスト・ボルフ・ゲーエムベーハー・ウント・コンパニー・カー・ゲー−アルツナイミツテル | 膣感染症における病原性膣バイオフィルムの予防及び治療のための両性界面活性剤の使用 |
| CN110693812A (zh) | 2012-06-13 | 2020-01-17 | 伊沃菲姆股份有限公司 | 用于增强避孕杀微生物剂有效性的组合物和方法 |
| US20150246065A1 (en) | 2012-09-14 | 2015-09-03 | Cipla Limited | Topical Pharmaceutical Composition |
| ITMI20130794A1 (it) * | 2013-05-14 | 2014-11-15 | Probiotical Spa | Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle vaginosi batteriche. |
| WO2015027071A1 (en) | 2013-08-21 | 2015-02-26 | Georgia Regents Research Institute, Inc. | Gpr81 agonists and methods thereof for promoting production of secretory iga |
| WO2015070072A1 (en) | 2013-11-07 | 2015-05-14 | Evofem, Inc. | Methods for manufacturing contraceptive microbicides with antiviral properties |
| AU2014368971B2 (en) | 2013-12-19 | 2020-02-06 | Evofem, Inc. | Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound |
| US9801839B2 (en) | 2014-02-28 | 2017-10-31 | Macfarlane Burnet Institute For Medical Research And Public Health Pty Ltd | Therapeutic method |
| WO2018049326A1 (en) | 2016-09-12 | 2018-03-15 | Evofem Biosciences, Inc. | Combination gel for sexually transmitted infections |
-
2017
- 2017-10-03 CN CN201780070201.0A patent/CN110225750A/zh active Pending
- 2017-10-03 WO PCT/US2017/054943 patent/WO2018067568A1/en not_active Ceased
- 2017-10-03 JP JP2019538583A patent/JP2019529572A/ja active Pending
- 2017-10-03 US US16/338,977 patent/US11419835B2/en active Active
- 2017-10-03 AU AU2017338748A patent/AU2017338748A1/en not_active Abandoned
- 2017-10-03 EP EP17859019.6A patent/EP3522879A4/en not_active Withdrawn
-
2022
- 2022-08-04 JP JP2022124559A patent/JP2022169581A/ja active Pending
- 2022-08-19 US US17/821,157 patent/US20230081059A1/en not_active Abandoned
-
2024
- 2024-06-12 JP JP2024094902A patent/JP2024138259A/ja active Pending
- 2024-07-05 JP JP2024109033A patent/JP2024133639A/ja active Pending
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