|
US3865939A
(en)
|
1973-02-23 |
1975-02-11 |
Procter & Gamble |
Edible oils having hypocholesterolemic properties
|
|
SE8600632D0
(sv)
|
1986-02-13 |
1986-02-13 |
Kabivitrum Ab |
Novel pharmaceutical composition
|
|
US5120723A
(en)
|
1987-08-25 |
1992-06-09 |
University Of Southern California |
Method, compositions, and compounds for modulating brain excitability
|
|
US5232917A
(en)
|
1987-08-25 |
1993-08-03 |
University Of Southern California |
Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
|
|
US5319115A
(en)
|
1987-08-25 |
1994-06-07 |
Cocensys Inc. |
Method for making 3α-hydroxy, 3β-substituted-pregnanes
|
|
US5719197A
(en)
|
1988-03-04 |
1998-02-17 |
Noven Pharmaceuticals, Inc. |
Compositions and methods for topical administration of pharmaceutically active agents
|
|
KR0166088B1
(ko)
|
1990-01-23 |
1999-01-15 |
. |
수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
|
|
US5497763A
(en)
|
1993-05-21 |
1996-03-12 |
Aradigm Corporation |
Disposable package for intrapulmonary delivery of aerosolized formulations
|
|
AU698834B2
(en)
|
1993-05-24 |
1998-11-12 |
Purdue Pharma Ltd. |
Methods and compositions for inducing sleep
|
|
KR100338287B1
(ko)
|
1994-02-14 |
2002-11-30 |
푸르듀 파머 리미티드 |
감마-아미노부티르산a수용체의알로오스테리조절용안드로스탄및프레그난
|
|
FI972202L
(fi)
|
1994-11-23 |
1997-07-17 |
Cocensys Inc |
Androstaanit ja pregnaanit GABA-reseptoreiden allosteeriseen muunteluun
|
|
RU2194712C2
(ru)
|
1995-06-06 |
2002-12-20 |
Коукенсис, Инк. |
НЕЙРОАКТИВНЫЕ СТЕРОИДЫ, ФАРМАЦЕВТИЧЕСКИЙ ПРЕПАРАТ, СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАЗЛИЧНЫХ НАРУШЕНИЙ, СПОСОБ ИНДУКЦИИ СНА И СПОСОБ ИНДУКЦИИ АНЕСТЕЗИИ С ИХ ИСПОЛЬЗОВАНИЕМ, СПОСОБ МОДУЛИРОВАНИЯ КОМПЛЕКСА РЕЦЕПТОР ГАМКa-ХЛОРИДНЫЙ ИОНОФОР
|
|
US6780853B1
(en)
|
1995-06-06 |
2004-08-24 |
Euro-Celtique S.A. |
Neuroactive steroids of the androstane and pregnane series
|
|
JP4313435B2
(ja)
|
1995-07-24 |
2009-08-12 |
トラスティーズ オブ ボストン ユニバーシティー |
プレグネノロンサルフェート誘導体によるｎｍｄａレセプター活性の抑制
|
|
US7630757B2
(en)
|
1997-01-06 |
2009-12-08 |
Flint Hills Scientific Llc |
System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
|
|
US6245757B1
(en)
|
1997-10-03 |
2001-06-12 |
Research Corporation Technologies, Inc. |
Use of progestins to treat ischemic event
|
|
CN1270718C
(zh)
*
|
1998-03-11 |
2006-08-23 |
托布乔恩·贝克斯托罗姆 |
表别孕烷醇酮在制备治疗甾族化合物诱导的疾病的药物中的应用
|
|
EP1175390B1
(en)
|
1999-04-05 |
2005-02-02 |
Emisphere Technologies, Inc. |
Disodium salts, monohydrates, and ethanol solvates
|
|
US20030236236A1
(en)
|
1999-06-30 |
2003-12-25 |
Feng-Jing Chen |
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
|
|
US6613308B2
(en)
|
2000-09-19 |
2003-09-02 |
Advanced Inhalation Research, Inc. |
Pulmonary delivery in treating disorders of the central nervous system
|
|
US20020072509A1
(en)
|
2000-10-11 |
2002-06-13 |
Stein Donald Gerald |
Methods for the treatment of a traumatic central nervous system injury
|
|
GR1003861B
(el)
|
2000-12-29 |
2002-04-11 |
|
Νεα νευροστεροειδη που αλληλεπιδρουν με τον υποδοχεα gabaa.
|
|
CA2641760A1
(en)
|
2001-05-24 |
2002-11-28 |
Alexza Pharmaceuticals, Inc. |
Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route
|
|
US20030032638A1
(en)
|
2001-05-24 |
2003-02-13 |
Kim John J. |
Delivery of benzodiazepines through an inhalation route
|
|
US7090830B2
(en)
|
2001-05-24 |
2006-08-15 |
Alexza Pharmaceuticals, Inc. |
Drug condensation aerosols and kits
|
|
JP2003063965A
(ja)
|
2001-06-13 |
2003-03-05 |
Otsuka Pharmaceut Factory Inc |
注射用シロスタゾール水性製剤
|
|
US8354438B2
(en)
|
2001-08-08 |
2013-01-15 |
Michael Chez |
Neurological functions
|
|
EP2298315A1
(en)
|
2002-08-28 |
2011-03-23 |
Harbor BioSciences, Inc. |
Therapeutic treatment methods
|
|
WO2005000869A1
(en)
|
2003-05-29 |
2005-01-06 |
Washington University |
Neuroactive 13,24-cyclo-18,21-dinorcholanes and structurally-related pentacyclic steroids
|
|
WO2005011612A2
(en)
|
2003-07-31 |
2005-02-10 |
The Research Foundation Of State University Of New York |
Alpha 4 beta 2 delta gaba-a receptors as a strategy for pms and alcoholism
|
|
GB0321607D0
(en)
|
2003-09-15 |
2003-10-15 |
Vectura Ltd |
Manufacture of pharmaceutical compositions
|
|
US7540286B2
(en)
|
2004-06-03 |
2009-06-02 |
Alexza Pharmaceuticals, Inc. |
Multiple dose condensation aerosol devices and methods of forming condensation aerosols
|
|
WO2006034196A1
(en)
|
2004-09-17 |
2006-03-30 |
Lifelike Biomatic Inc. |
Compositions for enhancing memory and methods therefor
|
|
WO2006037016A2
(en)
*
|
2004-09-27 |
2006-04-06 |
The Regents Of The University Of California |
Novel therapy for treatment of chronic degenerative brain diseases and nervous system injury
|
|
MX2007009915A
(es)
|
2005-02-15 |
2007-11-06 |
Elan Pharma Int Ltd |
Formulaciones en aerosol e inyectables de benzodiazepina nanoparticulada.
|
|
US20090325920A1
(en)
|
2005-03-24 |
2009-12-31 |
Emory University |
Methods for the treatment of a traumatic central nervous system injury
|
|
EP1868593A2
(en)
|
2005-04-07 |
2007-12-26 |
Hythiam, Inc. |
Improved methods of and compositions for the prevention of anxiety, substance abuse, and dependence
|
|
US20110319386A1
(en)
|
2005-08-26 |
2011-12-29 |
Braincells Inc. |
Neurogenesis by muscarinic receptor modulation
|
|
CN101583620B
(zh)
|
2005-11-28 |
2016-08-17 |
马里纳斯医药公司 |
加奈索酮组合物及其制备和使用方法
|
|
US20070287931A1
(en)
|
2006-02-14 |
2007-12-13 |
Dilorenzo Daniel J |
Methods and systems for administering an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
|
|
US20080026918A1
(en)
*
|
2006-07-27 |
2008-01-31 |
Michael Lemke |
Athletic training device with multi-directional movement
|
|
US20090239942A1
(en)
|
2006-09-15 |
2009-09-24 |
Cloyd James C |
Topiramate Compositions and Methods of Making and Using the Same
|
|
US20090203658A1
(en)
|
2007-01-08 |
2009-08-13 |
Duke University |
Neuroactive steroid compositions and methods of use therefor
|
|
US20090074677A1
(en)
|
2007-01-08 |
2009-03-19 |
Duke University |
Neuroactive steroid compositions and methods of use therefor
|
|
US7813811B2
(en)
|
2007-02-08 |
2010-10-12 |
Neuropace, Inc. |
Refillable reservoir lead systems
|
|
US20080243022A1
(en)
|
2007-03-30 |
2008-10-02 |
Donnett James G |
Seizure prediction using brain signal telemetry
|
|
US8530463B2
(en)
|
2007-05-07 |
2013-09-10 |
Hale Biopharma Ventures Llc |
Multimodal particulate formulations
|
|
WO2008154579A1
(en)
|
2007-06-11 |
2008-12-18 |
University Of Southern California |
Allopregnanolone in a method for enhancing neurological function (alzheimer disease)
|
|
WO2008157460A1
(en)
|
2007-06-15 |
2008-12-24 |
Cook, Kevin, M. |
Androstane and pregnane steroids with potent allosteric gaba receptor chloride ionophore modulating properties
|
|
GB0711948D0
(en)
|
2007-06-20 |
2007-08-01 |
Bionature E A Ltd |
Neurosteriod compounds
|
|
US20100316678A1
(en)
|
2007-06-28 |
2010-12-16 |
Cnsbio Pty Ltd. |
Combination methods and compositions for treatment of neuropathic pain
|
|
US9788744B2
(en)
|
2007-07-27 |
2017-10-17 |
Cyberonics, Inc. |
Systems for monitoring brain activity and patient advisory device
|
|
US20100297181A1
(en)
|
2007-12-26 |
2010-11-25 |
Eisai R&D Management Co., Ltd. |
AMPA Receptor Antagonists for Epilepsy, Mental Disorders or Deficits in Sensory Organ
|
|
US20090198145A1
(en)
|
2008-02-06 |
2009-08-06 |
Chow Harrison |
Compositions, methods, and systems for rapid induction and maintenance of continuous rem sleep
|
|
US8729070B2
(en)
|
2008-02-20 |
2014-05-20 |
Targia Pharmaceuticals |
CNS pharmaceutical compositions and methods of use
|
|
WO2010063030A2
(en)
|
2008-11-30 |
2010-06-03 |
Feigelson, Daniel |
Dermal application of vasoconstrictors
|
|
HRP20170357T1
(hr)
|
2008-10-10 |
2017-05-05 |
Vm Discovery, Inc. |
Sastavi i postupci za liječenje poremećaja zbog konzumacije alkohola, bolova i ostalih bolesti
|
|
US20100168603A1
(en)
|
2008-12-23 |
2010-07-01 |
Himes David M |
Brain state analysis based on select seizure onset characteristics and clinical manifestations
|
|
WO2010088409A2
(en)
|
2009-01-30 |
2010-08-05 |
Emory University |
Methods of neuroprotection using neuroprotective steroids and a vitamin d
|
|
WO2010097700A1
(en)
*
|
2009-02-25 |
2010-09-02 |
Supratek Pharma, Inc. |
Bendamustine cyclopolysaccharide compositions
|
|
WO2010107922A1
(en)
|
2009-03-17 |
2010-09-23 |
Duke University |
Neuroactive steroid compositions and methods of use for lowering cholesterol
|
|
US20110152840A1
(en)
|
2009-12-23 |
2011-06-23 |
Drugtech Corporation |
Methods for reducing the occurrence of preterm delivery and other pregnancy-related conditions
|
|
RU2574022C2
(ru)
|
2010-01-21 |
2016-01-27 |
Дробридж Фармасьютикалз Пти Лтд. |
Анестезирующий состав
|
|
CA2816806A1
(en)
|
2010-11-03 |
2012-05-10 |
Sanofi-Aventis Deutschland Gmbh |
Needle cannula containing medicament
|
|
WO2012075286A2
(en)
|
2010-12-01 |
2012-06-07 |
The Regents Of The University Of California |
Intrapulmonary benzodiazepine for the treatment and prevention of seizures
|
|
US9084797B2
(en)
|
2011-05-23 |
2015-07-21 |
Besins Healthcare Luxembourg Sarl |
Progesterone treatment for improving sleep quality
|
|
JP5893135B2
(ja)
|
2011-06-28 |
2016-03-23 |
ビボゾーン インコーポレイテッド |
多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途
|
|
JP2014521662A
(ja)
|
2011-07-29 |
2014-08-28 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ＧＡＢＡＡ受容体のモジュレーターとしての新規な１７β−ヘテロアリール置換ステロイド
|
|
HRP20230747T1
(hr)
|
2011-09-08 |
2024-01-05 |
Sage Therapeutics, Inc. |
Neuroaktivni steroidi, pripravci i njihova uporaba
|
|
US10478505B2
(en)
|
2011-09-23 |
2019-11-19 |
The Regents Of The University Of California |
Edible oils to enhance delivery of orally administered steroids
|
|
CN119192266A
(zh)
|
2011-10-14 |
2024-12-27 |
萨奇治疗股份有限公司 |
3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途
|
|
CA2856599C
(en)
|
2011-11-29 |
2017-05-30 |
Amino Up Chemical Co., Ltd. |
Composition comprising vicenin-2 having a beneficial effect on neurological and/or cognitive function
|
|
SG10201606063RA
(en)
*
|
2012-01-23 |
2016-09-29 |
Sage Therapeutics Inc |
Neuroactive steroid formulations and methods of treating cns disorders
|
|
US20150175651A1
(en)
|
2012-06-15 |
2015-06-25 |
Sage Therapeutics, Inc. |
Neuroactive steroids, compositions, and uses thereof
|
|
US20140050789A1
(en)
|
2012-08-13 |
2014-02-20 |
The Regents Of The University Of California |
Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
|
|
MX2015002252A
(es)
|
2012-08-21 |
2015-07-21 |
Sage Therapeutics Inc |
Metodos para tratar epilepsia o estado de epilepsia.
|
|
WO2014071449A1
(en)
|
2012-11-09 |
2014-05-15 |
Goodchild Investments Pty Ltd |
Neuroactive steroids and their use to facilitate neuroprotection
|
|
DK2925327T3
(da)
|
2012-11-30 |
2024-03-25 |
Univ California |
Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression
|
|
WO2014108808A2
(en)
|
2013-01-09 |
2014-07-17 |
Henry James Lorne |
Pharmaceutical formulations for the treatment and prevention of trauma-induced neuropathology and neurodegeneration
|
|
WO2015195962A1
(en)
|
2014-06-18 |
2015-12-23 |
Sage Therapeutics, Inc. |
Neuroactive steroids, compositions, and uses thereof
|
|
EP3362069A4
(en)
|
2015-10-14 |
2019-10-02 |
The Regents of The University of California |
INCREASING BETA CELL REPLICATION AND / OR SURVIVAL
|
|
HK1258616A1
(zh)
|
2016-03-08 |
2019-11-15 |
Sage Therapeutics, Inc. |
神经活性类固醇、组合物、及其用途
|
|
US20180050005A1
(en)
|
2016-08-16 |
2018-02-22 |
Janssen Pharmaceutica Nv |
Concentrated Solution of 17-Hydroxydocosahexaenoic Acid
|
|
US20180050107A1
(en)
|
2016-08-16 |
2018-02-22 |
Janssen Pharmaceutica Nv |
Neurosteroid compositions and methods of use thereof
|
|
CN110072523A
(zh)
|
2016-09-07 |
2019-07-30 |
格利亚有限责任公司 |
通过脑神经的药理皮肤激活来治疗与神经退行性病症相关的症状
|
|
US10391105B2
(en)
|
2016-09-09 |
2019-08-27 |
Marinus Pharmaceuticals Inc. |
Methods of treating certain depressive disorders and delirium tremens
|