JP2019529572A5 - - Google Patents
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- JP2019529572A5 JP2019529572A5 JP2019538583A JP2019538583A JP2019529572A5 JP 2019529572 A5 JP2019529572 A5 JP 2019529572A5 JP 2019538583 A JP2019538583 A JP 2019538583A JP 2019538583 A JP2019538583 A JP 2019538583A JP 2019529572 A5 JP2019529572 A5 JP 2019529572A5
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- Prior art keywords
- pharmaceutical composition
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- treatment process
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- Prior art date
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- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 238000000034 method Methods 0.000 claims 15
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims 10
- 208000037009 Vaginitis bacterial Diseases 0.000 claims 10
- 238000011282 treatment Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 9
- 238000011221 initial treatment Methods 0.000 claims 6
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 239000002562 thickening agent Substances 0.000 claims 4
- 229920001661 Chitosan Polymers 0.000 claims 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 241000287436 Turdus merula Species 0.000 claims 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 2
- 239000000783 alginic acid Substances 0.000 claims 2
- 235000010443 alginic acid Nutrition 0.000 claims 2
- 229920000615 alginic acid Polymers 0.000 claims 2
- 229960001126 alginic acid Drugs 0.000 claims 2
- 150000004781 alginic acids Chemical class 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 2
- 229940071676 hydroxypropylcellulose Drugs 0.000 claims 2
- -1 polycarbofyl Polymers 0.000 claims 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000000230 xanthan gum Substances 0.000 claims 2
- 229920001285 xanthan gum Polymers 0.000 claims 2
- 235000010493 xanthan gum Nutrition 0.000 claims 2
- 229940082509 xanthan gum Drugs 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022124559A JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404061P | 2016-10-04 | 2016-10-04 | |
| US62/404,061 | 2016-10-04 | ||
| PCT/US2017/054943 WO2018067568A1 (en) | 2016-10-04 | 2017-10-03 | Method of treatment and prevention of bacterial vaginosis |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124559A Division JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Division JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019529572A JP2019529572A (ja) | 2019-10-17 |
| JP2019529572A5 true JP2019529572A5 (enExample) | 2020-11-05 |
Family
ID=61831547
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019538583A Pending JP2019529572A (ja) | 2016-10-04 | 2017-10-03 | 細菌性膣炎の治療および予防方法 |
| JP2022124559A Pending JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Pending JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A Pending JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022124559A Pending JP2022169581A (ja) | 2016-10-04 | 2022-08-04 | 細菌性膣炎の治療および予防方法 |
| JP2024094902A Pending JP2024138259A (ja) | 2016-10-04 | 2024-06-12 | 細菌性膣炎の治療および予防方法 |
| JP2024109033A Pending JP2024133639A (ja) | 2016-10-04 | 2024-07-05 | 細菌性膣炎の治療および予防方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11419835B2 (enExample) |
| EP (1) | EP3522879A4 (enExample) |
| JP (4) | JP2019529572A (enExample) |
| CN (1) | CN110225750A (enExample) |
| AU (1) | AU2017338748A1 (enExample) |
| WO (1) | WO2018067568A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104487054A (zh) | 2012-06-13 | 2015-04-01 | 伊沃菲姆股份有限公司 | 用于增强避孕杀微生物剂有效性的组合物和方法 |
| AU2019359210A1 (en) * | 2018-10-09 | 2021-06-03 | Crapaud Bio, Inc. | Methods of making and using pH modulating compositions in the reproductive system |
| JP7706226B2 (ja) * | 2020-06-26 | 2025-07-11 | 小林製薬株式会社 | 粘膜洗浄用組成物 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1213323B (it) | 1986-08-07 | 1989-12-20 | Crinos Industria Farmaco | Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida |
| US4999342A (en) | 1988-08-16 | 1991-03-12 | Ortho Pharmaceutical Corporation | Long lasting contraceptive suppository composition and methods of use |
| JP3202365B2 (ja) | 1992-12-04 | 2001-08-27 | 株式会社紀文フードケミファ | オリゴマンヌロン酸を重合度によって分離する方法 |
| US5592949A (en) | 1994-06-29 | 1997-01-14 | Moench; Thomas R. | Device for acidic buffering and method for inactivation of pathogens |
| US5667492A (en) | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
| FR2728464B1 (fr) | 1994-12-22 | 1997-04-30 | Innothera Lab Sa | Forme galenique unitaire, son procede d'obtention et ses utilisations |
| US6093394A (en) | 1997-04-11 | 2000-07-25 | Gynelogix, Inc. | Vaginal lactobacillus medicant |
| ATE207755T1 (de) * | 1998-04-30 | 2001-11-15 | Vesely Renata Maria Cavaliere | Pharmazeutische zusammensetzungen enthaltend lactobacillus brevis und lactobacillus salivarius zur behandlung von vaginainfektionen |
| AU1661901A (en) | 1999-11-24 | 2001-06-04 | Cargill Dow Llc | Improved lactic acid processing; methods; arrangements; and, products |
| RU2274442C2 (ru) | 2000-03-07 | 2006-04-20 | Раш-Презбитериан-Ст. Лук'С Медикал Сентер | Композиции и способы улавливания и инактивации патогенных микроорганизмов и сперматозоидов |
| JP2009102407A (ja) | 2001-03-08 | 2009-05-14 | Rohto Pharmaceut Co Ltd | Ｇリッチなアルギン酸含有組成物 |
| US20020177624A1 (en) | 2001-03-16 | 2002-11-28 | Calvin Hanna | Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis |
| ITMI20010913A1 (it) | 2001-05-04 | 2002-11-04 | Univ Pavia | Composizioni a rilascio controllato di acido lattico a livello vaginale |
| JP2004537525A (ja) | 2001-06-11 | 2004-12-16 | メルク エンド カムパニー インコーポレーテッド | ＰＰＡＲδアゴニストの投与による炎症性疾患の治療法 |
| US7291477B2 (en) * | 2001-07-03 | 2007-11-06 | Xenotope Diagnostics, Inc. | Method and device for trichomonas detection |
| US20060105008A1 (en) * | 2002-03-28 | 2006-05-18 | Nawaz Ahmad | Compositions and methods for reducing vaginal pH |
| US20130150810A1 (en) | 2002-04-30 | 2013-06-13 | The Population Council, Inc. | Intravaginal ring for the delivery of unique combinations of antimicrobial compositions |
| WO2004011032A1 (ja) | 2002-07-26 | 2004-02-05 | Mikasa Seiyaku Co., Ltd. | 外用剤 |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| EP1635847B1 (en) * | 2003-06-13 | 2019-07-31 | IDH Holding ApS | Treatment of symptoms associated with bacterial vaginosis |
| US20050272700A1 (en) | 2004-05-10 | 2005-12-08 | Servet Buyuktimkin | Topical treatment and prevention of human papilloma virus (HPV) infection |
| RU2257197C1 (ru) | 2004-05-12 | 2005-07-27 | Дулькис Мария Дмитриевна | Вагинальные суппозитории, обладающие контрацептивным действием |
| UA93354C2 (ru) | 2004-07-09 | 2011-02-10 | Гилиад Сайенсиз, Инк. | Местный противовирусный препарат |
| CN101534863A (zh) | 2006-11-10 | 2009-09-16 | 日本乐敦制药株式会社 | 用于向皮肤或粘膜施用的组合物 |
| US7659259B2 (en) | 2006-12-21 | 2010-02-09 | Bausch & Lomb Incorporated | Method of treating inflammation of the eye |
| HRP20140559T1 (hr) | 2007-03-30 | 2014-08-01 | Laccure Ab | Uporaba oligomera mlijeäśne kiseline u lijeäśenju ginekoloških infekcija |
| WO2008148018A2 (en) | 2007-05-24 | 2008-12-04 | New York Blood Center Inc. | Rapidly dispersible vaginal tablet that provides a bioadhesive gel |
| TW200927141A (en) | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| EP2282777A1 (en) | 2008-04-16 | 2011-02-16 | Cipla Limited | Topical combinations comprising an antimycotic agent and an antiviral agent |
| WO2009155118A1 (en) | 2008-05-30 | 2009-12-23 | Reprotect, Inc. | Compositions and methods for inactivation of pathogens at genital tract surfaces |
| EP2130531A1 (en) | 2008-06-04 | 2009-12-09 | Rolf Kullgren AB | Vaginal suppository comprising lactic acid |
| US20120070476A1 (en) * | 2009-05-29 | 2012-03-22 | Moench Thomas R | Compositions and Methods for Inactivation of Pathogens at Genital Tract Surfaces |
| WO2010142761A1 (en) | 2009-06-10 | 2010-12-16 | Ultimorphix Technologies B.V. | The succinate of tenofovir disoproxil |
| KR20160112012A (ko) | 2011-05-02 | 2016-09-27 | 아데어 파마슈티컬스 인코포레이티드 | 질내 투여용 속용성 정제 조성물 |
| JP5986632B2 (ja) | 2011-06-28 | 2016-09-06 | メディシス ファーマシューティカル コーポレイション | 高用量粘膜接着性メトロニダゾール水系ゲル製剤および細菌性膣炎を治療するためのそれらの使用 |
| EP2827854A1 (en) * | 2012-03-19 | 2015-01-28 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Use of amphoteric surfactants for the prevention and treatment of pathogenic vaginal biofilms in vaginal infections |
| CN104487054A (zh) * | 2012-06-13 | 2015-04-01 | 伊沃菲姆股份有限公司 | 用于增强避孕杀微生物剂有效性的组合物和方法 |
| MX2015003262A (es) * | 2012-09-14 | 2016-06-10 | Cipla Ltd | Composicion farmaceutica topica. |
| ITMI20130794A1 (it) * | 2013-05-14 | 2014-11-15 | Probiotical Spa | Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle vaginosi batteriche. |
| WO2015027071A1 (en) | 2013-08-21 | 2015-02-26 | Georgia Regents Research Institute, Inc. | Gpr81 agonists and methods thereof for promoting production of secretory iga |
| WO2015070072A1 (en) * | 2013-11-07 | 2015-05-14 | Evofem, Inc. | Methods for manufacturing contraceptive microbicides with antiviral properties |
| MX2016008023A (es) | 2013-12-19 | 2017-01-13 | Evofem Inc | Composiciones y metodos para inhibir la inflamacion y las enfermedades utilizando un compuesto antimicrobiano con base en acido alginico. |
| AU2015201042A1 (en) | 2014-02-28 | 2015-09-17 | Macfarlane Burnet Institute For Medical Research And Public Health Pty Ltd | Therapeutic Method |
| US20190209502A1 (en) | 2016-09-12 | 2019-07-11 | Evofem, Inc. | Combination gel for sexually transmitted infections |
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2017
- 2017-10-03 US US16/338,977 patent/US11419835B2/en active Active
- 2017-10-03 JP JP2019538583A patent/JP2019529572A/ja active Pending
- 2017-10-03 CN CN201780070201.0A patent/CN110225750A/zh active Pending
- 2017-10-03 WO PCT/US2017/054943 patent/WO2018067568A1/en not_active Ceased
- 2017-10-03 AU AU2017338748A patent/AU2017338748A1/en not_active Abandoned
- 2017-10-03 EP EP17859019.6A patent/EP3522879A4/en not_active Withdrawn
-
2022
- 2022-08-04 JP JP2022124559A patent/JP2022169581A/ja active Pending
- 2022-08-19 US US17/821,157 patent/US20230081059A1/en not_active Abandoned
-
2024
- 2024-06-12 JP JP2024094902A patent/JP2024138259A/ja active Pending
- 2024-07-05 JP JP2024109033A patent/JP2024133639A/ja active Pending