JP2019528810A - 疾患材料の検出、捕捉、または除去のための流体デバイス - Google Patents

疾患材料の検出、捕捉、または除去のための流体デバイス Download PDF

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JP2019528810A
JP2019528810A JP2019500495A JP2019500495A JP2019528810A JP 2019528810 A JP2019528810 A JP 2019528810A JP 2019500495 A JP2019500495 A JP 2019500495A JP 2019500495 A JP2019500495 A JP 2019500495A JP 2019528810 A JP2019528810 A JP 2019528810A
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disease material
fluidic device
blood
disease
flow path
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JP2019528810A5 (https=
Inventor
イー． ミラー，シネイド
イー． ミラー，シネイド
エス． ベル，チャールソン
エス． ベル，チャールソン
エル． クック，アンドリュー
エル． クック，アンドリュー
ディー． ジョルジオ，トッド
ディー． ジョルジオ，トッド
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ヴァンダービルト ユニヴァーシティ
ヴァンダービルト ユニヴァーシティ
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Publication of JP2019528810A publication Critical patent/JP2019528810A/ja
Publication of JP2019528810A5 publication Critical patent/JP2019528810A5/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019500495A 2016-07-07 2017-07-07 疾患材料の検出、捕捉、または除去のための流体デバイス Withdrawn JP2019528810A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022129921A JP2022176962A (ja) 2016-07-07 2022-08-17 疾患材料の検出、捕捉、または除去のための流体デバイス

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662359322P 2016-07-07 2016-07-07
US62/359,322 2016-07-07
US201662407767P 2016-10-13 2016-10-13
US62/407,767 2016-10-13
US201762454235P 2017-02-03 2017-02-03
US62/454,235 2017-02-03
US201762478904P 2017-03-30 2017-03-30
US62/478,904 2017-03-30
PCT/US2017/041038 WO2018009756A1 (en) 2016-07-07 2017-07-07 Fluidic device for the detection, capture, or removal of a disease material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022129921A Division JP2022176962A (ja) 2016-07-07 2022-08-17 疾患材料の検出、捕捉、または除去のための流体デバイス

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JP2019528810A true JP2019528810A (ja) 2019-10-17
JP2019528810A5 JP2019528810A5 (https=) 2020-08-13

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JP2019500495A Withdrawn JP2019528810A (ja) 2016-07-07 2017-07-07 疾患材料の検出、捕捉、または除去のための流体デバイス
JP2022129921A Pending JP2022176962A (ja) 2016-07-07 2022-08-17 疾患材料の検出、捕捉、または除去のための流体デバイス

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US (2) US11154861B2 (https=)
EP (1) EP3482203A4 (https=)
JP (2) JP2019528810A (https=)
CN (1) CN109791146A (https=)
CA (1) CA3030138A1 (https=)
WO (1) WO2018009756A1 (https=)

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EP3870969A4 (en) * 2018-10-24 2022-07-27 Path Ex, Inc. PROCESS FOR RECOVERING AND ISOLATION OF DISEASE MATERIAL FROM FLOWING MATERIAL
CN109082368A (zh) * 2018-10-29 2018-12-25 上海理工大学 循环肿瘤细胞分选、富集及检测用多级微流控芯片装置
WO2020102533A1 (en) * 2018-11-15 2020-05-22 Massachusetts Institute Of Technology Multi-dimensional double spiral device and methods of use thereof
WO2021063708A1 (en) * 2019-09-30 2021-04-08 Hemotune Ag Assembly for extracorporeal treatment of body fluids
KR20210043207A (ko) * 2019-10-11 2021-04-21 주식회사 싸이토딕스 비편향적 순환종양세포 연속 분리 장치 및 방법
WO2021144769A1 (en) 2020-01-17 2021-07-22 Wynnvision, Llc Antimicrobial silicones
US20210237064A1 (en) * 2020-01-31 2021-08-05 Astrin Biosciences, Inc. Biological Fluid Filtration System
US20230381393A1 (en) * 2022-05-27 2023-11-30 Actorius Innovations Research Co Devices and methods for recovering disease-causing toxic constituents in the blood
CN115107285B (zh) * 2022-06-16 2024-04-02 乾德生物医疗技术(重庆)有限公司 血液净化装置的制造方法
WO2024038432A1 (en) * 2022-08-13 2024-02-22 Adrian Paz Circulating tumor cells collection and therapy system
CN117050764B (zh) * 2023-09-11 2024-04-05 华南理工大学 一种抗生素菌渣多步热解制备高含量可燃气体的方法

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JP2003265606A (ja) * 2002-03-14 2003-09-24 Toray Ind Inc 体外循環用毒素吸着材
JP2008510974A (ja) * 2004-08-23 2008-04-10 カーイーエステー−オイローパ フォルシュングスゲゼルシャフト エムベーハー 免疫磁気分離法を用いて生物粒子を単離するためのマイクロ流体システム
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EP3482203A4 (en) 2020-01-01
US11154861B2 (en) 2021-10-26
US20220134341A1 (en) 2022-05-05
WO2018009756A1 (en) 2018-01-11
EP3482203A1 (en) 2019-05-15
JP2022176962A (ja) 2022-11-30
US11883821B2 (en) 2024-01-30
CN109791146A (zh) 2019-05-21
US20190240663A1 (en) 2019-08-08
CA3030138A1 (en) 2018-01-11

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