JP2019528677A5 - - Google Patents
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- Publication number
- JP2019528677A5 JP2019528677A5 JP2018566591A JP2018566591A JP2019528677A5 JP 2019528677 A5 JP2019528677 A5 JP 2019528677A5 JP 2018566591 A JP2018566591 A JP 2018566591A JP 2018566591 A JP2018566591 A JP 2018566591A JP 2019528677 A5 JP2019528677 A5 JP 2019528677A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- domain
- seq
- composition
- axl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1610902.7A GB201610902D0 (en) | 2016-06-22 | 2016-06-22 | Anti-Axl Antagonistic Antibodies |
| GB1610902.7 | 2016-06-22 | ||
| PCT/EP2017/065313 WO2017220695A1 (en) | 2016-06-22 | 2017-06-21 | Anti-axl antagonistic antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019528677A JP2019528677A (ja) | 2019-10-17 |
| JP2019528677A5 true JP2019528677A5 (enExample) | 2020-07-30 |
| JP7071935B2 JP7071935B2 (ja) | 2022-05-19 |
Family
ID=56895047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018566591A Expired - Fee Related JP7071935B2 (ja) | 2016-06-22 | 2017-06-21 | 抗Ａｘｌアンタゴニスト抗体 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11198734B2 (enExample) |
| EP (1) | EP3475305A1 (enExample) |
| JP (1) | JP7071935B2 (enExample) |
| KR (1) | KR102458196B1 (enExample) |
| CN (2) | CN116903748A (enExample) |
| AU (1) | AU2017281326A1 (enExample) |
| CA (1) | CA3025729A1 (enExample) |
| GB (1) | GB201610902D0 (enExample) |
| MX (1) | MX2018016096A (enExample) |
| WO (1) | WO2017220695A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016097370A2 (en) * | 2014-12-18 | 2016-06-23 | Bergen Teknologioverføring As | Anti-axl antagonistic antibodies |
| GB201610902D0 (en) * | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
| CN110483639A (zh) | 2018-05-15 | 2019-11-22 | 复旦大学 | 靶向axl的抗体及抗体-药物偶联物及其制备方法和用途 |
| GB201912059D0 (en) | 2019-08-22 | 2019-10-09 | Bergenbio As | Combaination therapy of a patient subgroup |
| NL2024108B1 (en) * | 2019-10-26 | 2021-07-19 | Vitroscan B V | Methods and apparatus for measuring immune-cell mediated anti-tumoroid responses |
| US11807688B2 (en) * | 2020-02-28 | 2023-11-07 | Les Laboratoires Servier | Anti-AXL antibodies and compositions |
| GB202004189D0 (en) | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
| WO2021204713A1 (en) | 2020-04-08 | 2021-10-14 | Bergenbio Asa | Axl inhibitors for antiviral therapy |
| GB202006072D0 (en) * | 2020-04-24 | 2020-06-10 | Bergenbio Asa | Method of selecting patients for treatment with cmbination therapy |
| WO2022164288A1 (ko) | 2021-01-29 | 2022-08-04 | 한국과학기술원 | 비염증성 식세포작용 유도 활성을 갖는 융합분자 |
| GB202104037D0 (en) | 2021-03-23 | 2021-05-05 | Bergenbio Asa | Combination therapy |
| AU2021451307A1 (en) * | 2021-06-16 | 2024-02-01 | Shanghai Sinobay Biotechnology Co., Ltd. | Antibody targeting axl protein and antigen binding fragment thereof, preparation method therefor and use thereof |
| EP4359439A1 (en) * | 2021-06-24 | 2024-05-01 | Yeda Research and Development Co. Ltd | Combination therapy for the treatment of cancer comprising an anti-egfr antibody and an axl-inhibitor |
| US20260042848A1 (en) * | 2022-08-18 | 2026-02-12 | BioLegend, Inc. | Anti-axl antibodies, antigen-binding fragments thereof and methods for making and using the same |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1382969A1 (en) | 2002-07-17 | 2004-01-21 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Diagnosis and prevention of cancer cell invasion |
| BRPI0820073A2 (pt) | 2007-11-12 | 2015-06-23 | U3 Pharma Gmbh | Anticorpos anti-axl |
| CN101918452A (zh) * | 2007-11-15 | 2010-12-15 | 中外制药株式会社 | 与Anexelekto结合的单克隆抗体及其利用 |
| AR076564A1 (es) | 2009-05-11 | 2011-06-22 | U3 Pharma Gmbh | Anticuerpos humanizados de axl(receptor de tirosina quinasa) |
| CN102459344A (zh) | 2009-05-15 | 2012-05-16 | 中外制药株式会社 | 抗axl抗体 |
| TW201106972A (en) | 2009-07-27 | 2011-03-01 | Genentech Inc | Combination treatments |
| CN103080136B (zh) * | 2010-06-18 | 2015-08-12 | 霍夫曼-拉罗奇有限公司 | 抗Axl抗体及使用方法 |
| AU2012273955A1 (en) | 2011-06-22 | 2014-01-09 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Anti-Axl antibodies and uses thereof |
| WO2012175691A1 (en) | 2011-06-22 | 2012-12-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-axl antibodies and uses thereof |
| EP2589609A1 (en) * | 2011-11-03 | 2013-05-08 | Pierre Fabre Medicament | Antigen binding protein and its use as addressing product for the treatment of cancer |
| KR102167228B1 (ko) * | 2012-11-05 | 2020-10-19 | 피에르 파브르 메디카먼트 | 새로운 항원 결합 단백질들 및 암의 치료를 위한 어드레싱 산물로서 그들의 용도 |
| US9850297B2 (en) * | 2013-03-15 | 2017-12-26 | Amgen Inc. | Secreted frizzle-related protein 5 (SFRP5) binding proteins |
| US20160106861A1 (en) * | 2013-04-26 | 2016-04-21 | Spirogen Sarl | Axl antibody-drug conjugate and its use for the treatment of cancer |
| CN106132992B (zh) * | 2014-01-29 | 2020-08-07 | 达娜-法勃肿瘤研究所公司 | 针对muc1-c/胞外结构域(muc1-c/ecd)的抗体 |
| GB201410826D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| GB201410825D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
| US9986723B2 (en) | 2014-10-22 | 2018-06-05 | The Board Of Regents Of The University Of Texas System | Screen and use of therapeutics for pancreatic ductal adenocarcinoma |
| EP3229836B1 (en) | 2014-12-09 | 2019-11-13 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Human monoclonal antibodies against axl |
| WO2016097370A2 (en) | 2014-12-18 | 2016-06-23 | Bergen Teknologioverføring As | Anti-axl antagonistic antibodies |
| GB201610902D0 (en) * | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
| US11159088B2 (en) * | 2019-06-19 | 2021-10-26 | Appulse Power Inc. | Dual path and mode start-up circuit |
| GB202004189D0 (en) * | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
-
2016
- 2016-06-22 GB GBGB1610902.7A patent/GB201610902D0/en not_active Ceased
-
2017
- 2017-06-21 CN CN202310799984.3A patent/CN116903748A/zh active Pending
- 2017-06-21 JP JP2018566591A patent/JP7071935B2/ja not_active Expired - Fee Related
- 2017-06-21 WO PCT/EP2017/065313 patent/WO2017220695A1/en not_active Ceased
- 2017-06-21 US US16/098,933 patent/US11198734B2/en not_active Expired - Fee Related
- 2017-06-21 AU AU2017281326A patent/AU2017281326A1/en not_active Abandoned
- 2017-06-21 CA CA3025729A patent/CA3025729A1/en active Pending
- 2017-06-21 MX MX2018016096A patent/MX2018016096A/es unknown
- 2017-06-21 CN CN201780038590.9A patent/CN109311997B/zh not_active Expired - Fee Related
- 2017-06-21 EP EP17732875.4A patent/EP3475305A1/en not_active Withdrawn
- 2017-06-21 KR KR1020187036968A patent/KR102458196B1/ko not_active Expired - Fee Related
-
2021
- 2021-11-02 US US17/516,916 patent/US11732048B2/en active Active
-
2023
- 2023-06-29 US US18/216,085 patent/US20240190972A1/en not_active Abandoned
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