JP2019524690A5 - - Google Patents

Download PDF

Info

Publication number
JP2019524690A5
JP2019524690A5 JP2018568951A JP2018568951A JP2019524690A5 JP 2019524690 A5 JP2019524690 A5 JP 2019524690A5 JP 2018568951 A JP2018568951 A JP 2018568951A JP 2018568951 A JP2018568951 A JP 2018568951A JP 2019524690 A5 JP2019524690 A5 JP 2019524690A5
Authority
JP
Japan
Prior art keywords
cancer
composition
patient
niraparib
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018568951A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019524690A (ja
JP7083760B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/040039 external-priority patent/WO2018005818A1/en
Publication of JP2019524690A publication Critical patent/JP2019524690A/ja
Publication of JP2019524690A5 publication Critical patent/JP2019524690A5/ja
Priority to JP2021212103A priority Critical patent/JP2022031478A/ja
Application granted granted Critical
Publication of JP7083760B2 publication Critical patent/JP7083760B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018568951A 2016-06-29 2017-06-29 卵巣癌の治療方法 Active JP7083760B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021212103A JP2022031478A (ja) 2016-06-29 2021-12-27 卵巣癌の治療方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662356461P 2016-06-29 2016-06-29
US62/356,461 2016-06-29
US201662402427P 2016-09-30 2016-09-30
US62/402,427 2016-09-30
US201762470141P 2017-03-10 2017-03-10
US62/470,141 2017-03-10
PCT/US2017/040039 WO2018005818A1 (en) 2016-06-29 2017-06-29 Methods of treating ovarian cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021212103A Division JP2022031478A (ja) 2016-06-29 2021-12-27 卵巣癌の治療方法

Publications (3)

Publication Number Publication Date
JP2019524690A JP2019524690A (ja) 2019-09-05
JP2019524690A5 true JP2019524690A5 (enExample) 2020-08-13
JP7083760B2 JP7083760B2 (ja) 2022-06-13

Family

ID=60787744

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018568951A Active JP7083760B2 (ja) 2016-06-29 2017-06-29 卵巣癌の治療方法
JP2021212103A Pending JP2022031478A (ja) 2016-06-29 2021-12-27 卵巣癌の治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021212103A Pending JP2022031478A (ja) 2016-06-29 2021-12-27 卵巣癌の治療方法

Country Status (24)

Country Link
US (5) US12383542B2 (enExample)
EP (2) EP4302835A3 (enExample)
JP (2) JP7083760B2 (enExample)
KR (2) KR20230042136A (enExample)
CN (1) CN109640992A (enExample)
AU (1) AU2017290244B2 (enExample)
BR (1) BR112018077492A2 (enExample)
CA (1) CA3029671C (enExample)
DK (1) DK3478286T3 (enExample)
ES (1) ES2969816T3 (enExample)
FI (1) FI3478286T3 (enExample)
HR (1) HRP20240136T1 (enExample)
HU (1) HUE064978T2 (enExample)
IL (1) IL263925B2 (enExample)
LT (1) LT3478286T (enExample)
MX (1) MX394062B (enExample)
NZ (1) NZ749413A (enExample)
PL (1) PL3478286T3 (enExample)
PT (1) PT3478286T (enExample)
RS (1) RS65180B1 (enExample)
SG (1) SG11201811564QA (enExample)
SI (1) SI3478286T1 (enExample)
SM (1) SMT202400105T1 (enExample)
WO (1) WO2018005818A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201811564QA (en) 2016-06-29 2019-01-30 Tesaro Inc Methods of treating ovarian cancer
EP3666794A1 (en) 2016-11-01 2020-06-17 AnaptysBio, Inc. Antibodies directed against programmed death- 1 (pd-1)
BR112019008861A2 (pt) 2016-11-01 2019-07-09 Tesaro, Inc. anticorpos direcionados contra imunoglobulina de células t e proteína de mucina 3 (tim-3)
BR112019014187A2 (pt) 2017-01-09 2020-02-11 Tesaro, Inc. Métodos de tratamento de câncer com anticorpos anti-pd-1
SG10201913083SA (en) 2017-01-09 2020-03-30 Tesaro Inc Methods of treating cancer with anti-tim-3 antibodies
EP3600314A1 (en) 2017-03-27 2020-02-05 Tesaro, Inc. Niraparib compositions
CN118271233A (zh) 2017-04-24 2024-07-02 特沙诺有限公司 尼拉帕利的制造方法
US12156872B2 (en) * 2017-05-09 2024-12-03 Tesaro, Inc. Combination therapies for treating cancer
CA3063715A1 (en) 2017-05-18 2018-11-22 Tesaro, Inc. Combination therapies for treating cancer
CA3076907A1 (en) 2017-09-26 2019-04-04 Tesaro, Inc. Niraparib formulations
CN111372607A (zh) 2017-09-30 2020-07-03 特沙诺有限公司 用于治疗癌症的联合疗法
US11801240B2 (en) 2017-10-06 2023-10-31 Tesaro, Inc. Combination therapies and uses thereof
CA3090479A1 (en) * 2018-02-05 2019-08-08 Tesaro, Inc Pediatric niraparib formulations and pediatric treatment methods
WO2019195443A1 (en) * 2018-04-04 2019-10-10 The Wistar Institute Of Anatomy And Biology Methods of treating cancers overexpressing carm1 with ezh2 inhibitors and a parp inhibitor
WO2020072796A1 (en) 2018-10-03 2020-04-09 Tesaro, Inc. Crystalline forms of niraparib freebase
TWI853841B (zh) 2018-10-03 2024-09-01 美商提薩羅有限公司 尼拉帕尼(niraparib)鹽
EP3857555A4 (en) 2018-10-17 2022-12-21 Tempus Labs DATA-BASED CANCER RESEARCH AND TREATMENT SYSTEMS AND PROCEDURES
US10395772B1 (en) 2018-10-17 2019-08-27 Tempus Labs Mobile supplementation, extraction, and analysis of health records
CA3122070A1 (en) 2018-12-03 2020-06-11 Tempus Labs, Inc. Clinical concept identification, extraction, and prediction system and related methods
JP2022516170A (ja) * 2019-01-04 2022-02-24 アクティニウム ファーマシューティカルズ インコーポレイテッド Parpインヒビターおよび抗体放射性物質結合体の組み合わせを使用してがんを処置するための方法
US11705226B2 (en) 2019-09-19 2023-07-18 Tempus Labs, Inc. Data based cancer research and treatment systems and methods
TW202116316A (zh) * 2019-07-15 2021-05-01 美商提薩羅有限公司 治療卵巢、輸卵管及腹膜癌之方法
US11295841B2 (en) * 2019-08-22 2022-04-05 Tempus Labs, Inc. Unsupervised learning and prediction of lines of therapy from high-dimensional longitudinal medications data
WO2021138215A1 (en) * 2019-12-31 2021-07-08 Kinnate Biopharma Inc. Treatment of cancer with cdk12/13 inhibitors
CA3158900A1 (en) * 2020-01-13 2021-07-22 John Nemunaitis Methods for treating cancers using gm-csf encoding polynucleotide and additional agents
UY39204A (es) * 2020-05-08 2021-11-30 Janssen Pharmaceutica Nv Formulaciones farmacéuticas de acetato de abiraterona y niraparib
KR20230113742A (ko) * 2020-10-29 2023-08-01 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 난소암의 검출 및 치료를 위한 방법
KR102858757B1 (ko) 2022-01-25 2025-09-10 서울대학교산학협력단 상동 재조합 결핍 연관 유전자 도출 장치 및 방법, 상동 재조합 결핍 판단 모델 생성 장치 및 방법과, 상동 재조합 결핍 판단 장치 및 방법
CN119156216A (zh) 2022-02-15 2024-12-17 特沙诺有限公司 尼拉帕尼用于治疗脑癌的用途
CN115253066A (zh) * 2022-07-21 2022-11-01 湖南安泰康成生物科技有限公司 卵巢癌治疗系统以及卵巢癌治疗的交变电场发生装置
CN116092631A (zh) * 2023-01-17 2023-05-09 湖南安泰康成生物科技有限公司 铁死亡诱导剂与电场联用的肿瘤治疗系统
WO2025061057A1 (en) * 2023-09-19 2025-03-27 Impact Therapeutics (Shanghai) , Inc Use of a parp inhibitor in maintenance therapy of ovarian cancer

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2647545C (en) 2006-04-03 2016-02-23 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
EP2805945B1 (en) 2007-01-10 2019-04-03 MSD Italia S.r.l. Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
JP5593229B2 (ja) 2007-10-17 2014-09-17 クドス ファーマシューティカルズ リミテッド 4−[3−(4−シクロプロパンカルボニル−ピペラジン−1−カルボニル)−4−フルオロ−ベンジル]−2h−フタラジン−1−オン
CA2705417A1 (en) * 2007-11-12 2009-05-22 Bipar Sciences, Inc. Treatment of uterine cancer and ovarian cancer with a parp inhibitor alone or in combination with anti-tumor agents
US8500933B2 (en) 2007-12-14 2013-08-06 Guardian Industries Corp. Localized heating of edge seals for a vacuum insulating glass unit, and/or unitized oven for accomplishing the same
JP5989965B2 (ja) 2008-01-08 2016-09-07 メルク シャープ エンド ドーム リミテッド 2−{4−[(3s)−ピペリジン−3−イル]フェニル}−2h−インダゾール−7−カルボキサミドの薬学的に許容される塩
EP2237684A2 (en) 2008-01-08 2010-10-13 Akthelia Pharmaceuticals Agonists for antimicrobial peptide systems
CN102482282A (zh) 2009-08-26 2012-05-30 赛福伦公司 多环化合物的新形式
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
WO2011153383A1 (en) 2010-06-04 2011-12-08 Bipar Science, Inc. Methods of treating platinum-resistant recurrent ovarian cancer with 4-iodo-3-nitrobenzamide in combination with an anti-metabolite and a platinum compound
DK2582847T3 (en) 2010-06-18 2016-12-19 Myriad Genetics Inc METHODS AND MATERIALS TO ASSESS loss of heterozygosity
WO2012027224A1 (en) 2010-08-24 2012-03-01 Dana-Farber Cancer Institute, Inc. Methods for predicting anti-cancer response
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
CA2742342A1 (en) 2011-02-12 2012-08-12 Baylor Research Institute Msh3 expression status determines the responsiveness of cancer cells to the chemotherapeutic treatment with parp inhibitors and platinum drugs
CA2779052A1 (en) 2012-05-31 2013-11-30 Pharmascience Inc. Pharmaceutical composition of entecavir and process of manufacturing
WO2013182645A1 (en) 2012-06-07 2013-12-12 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
WO2014052550A1 (en) * 2012-09-27 2014-04-03 Thomas Jefferson University Use of parp inhibitors to treat breast cancer
WO2014085698A1 (en) 2012-11-28 2014-06-05 Sloan-Kettering Institute For Cancer Research Compositions and methods for the treatment of cancers associated with a deficiency in the mre11/rad50/nbs1 dna damage repair complex
US9580407B2 (en) 2012-12-07 2017-02-28 Merck Sharp & Dohme Corp. Regioselective N-2 arylation of indazoles
US9738915B2 (en) 2012-12-07 2017-08-22 Merck Sharp & Dohme Corp. Biocatalytic transamination process
US9850542B2 (en) 2013-03-04 2017-12-26 Board Of Regents, The University Of Texas System Gene signature to predict homologous recombination (HR) deficient cancer
EP3693475A1 (en) * 2013-04-05 2020-08-12 Myriad Genetics, Inc. Methods and materials for assessing homologous recombination deficiency
KR102243062B1 (ko) 2013-05-02 2021-04-21 아납티스바이오, 아이엔씨. 예정된 사멸-1에 대한 항체
JP6663350B2 (ja) 2014-01-16 2020-03-11 クロヴィス・オンコロジー,インコーポレーテッド ヘテロ接合性の喪失を示す乳癌または卵巣癌の患者を治療するためのparp阻害剤の使用
WO2015119930A1 (en) 2014-02-04 2015-08-13 Pfizer Inc. Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer
AU2015228860A1 (en) 2014-03-13 2016-09-08 F. Hoffmann-La Roche Ag Methods and compositions for modulating estrogen receptor mutants
RU2016142476A (ru) 2014-03-31 2018-05-07 Дженентек, Инк. Комбинированная терапия, включающая антиангиогенезные агенты и агонисты, связывающие ох40
US10238630B2 (en) * 2014-05-28 2019-03-26 Eisai R&D Management Co., Ltd. Use of eribulin and poly (ADP ribose) polymerase (PARP) inhibitors as combination therapy for the treatment of cancer
US20150344968A1 (en) * 2014-05-30 2015-12-03 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Methods for determining parp inhibitor and platinum resistance in cancer therapy
CN105384695B (zh) * 2014-08-22 2019-12-20 四川海思科制药有限公司 嘧啶衍生物及其制备方法和在医药上的应用
CN112877426A (zh) 2014-08-25 2021-06-01 创新微技术公司 在血液中的循环细胞生物标记在检测和诊断疾病中的应用及其分离方法
EP3230472A4 (en) 2014-12-08 2018-06-13 Myriad Genetics, Inc. Methods and materials for predicting response to niraparib
US20170000885A1 (en) 2015-06-08 2017-01-05 Genentech, Inc. Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
DK3954690T3 (da) 2015-07-02 2023-06-06 Acerta Pharma Bv Faste former og formuleringer af (s)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamid
JP2018536700A (ja) 2015-10-26 2018-12-13 メディヴェイション テクノロジーズ, エルエルシー Parp阻害剤を用いる小細胞肺がんの治療
EP3414692A4 (en) 2016-02-12 2020-07-29 Nantomics, LLC HIGH-RATE IDENTIFICATION OF PATIENT-SPECIFIC NEOEPITOPES AS THERAPEUTIC TARGETS FOR CANCER IMMUNOTHERAPIES
WO2017151554A1 (en) * 2016-02-29 2017-09-08 Synta Pharmaceuticals Corp Combination therapy for treatment of ovarian cancer
SG11201811564QA (en) 2016-06-29 2019-01-30 Tesaro Inc Methods of treating ovarian cancer
MX2019001224A (es) 2016-07-29 2019-06-03 Janssen Pharmaceutica Nv Metodos para tratar el cancer de prostata.
CN106496187A (zh) 2016-09-14 2017-03-15 陕西科技大学 一种制备PARP抑制剂Niraparib的合成方法
CN106432055A (zh) 2016-09-17 2017-02-22 青岛辰达生物科技有限公司 一种尼拉帕布中间体4‑(哌啶‑3‑基)苯胺的制备方法
BR112019020191A2 (pt) 2017-03-27 2020-04-22 Tesaro Inc formulações de niraparib
EP3600314A1 (en) 2017-03-27 2020-02-05 Tesaro, Inc. Niraparib compositions
CN118271233A (zh) 2017-04-24 2024-07-02 特沙诺有限公司 尼拉帕利的制造方法
SG10201913677SA (en) 2017-04-27 2020-03-30 Tesaro Inc Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
US20200129482A1 (en) 2017-06-26 2020-04-30 Abbvie Inc. Treatment of non-small cell lung cancer
CA3076907A1 (en) 2017-09-26 2019-04-04 Tesaro, Inc. Niraparib formulations
TW201938165A (zh) 2017-12-18 2019-10-01 美商輝瑞股份有限公司 治療癌症的方法及組合療法
EP3731866A1 (en) 2017-12-27 2020-11-04 Tesaro Inc. Methods of treating cancer
TW202116316A (zh) 2019-07-15 2021-05-01 美商提薩羅有限公司 治療卵巢、輸卵管及腹膜癌之方法
KR102336493B1 (ko) 2019-11-22 2021-12-07 주식회사 메디풀 항균탈취 조성물 및 이의 제조방법

Similar Documents

Publication Publication Date Title
JP2019524690A5 (enExample)
FI3478286T3 (fi) Menetelmiä munasarjasyövän hoitamiseksi
JP2022031478A5 (enExample)
JP2014530874A5 (enExample)
MX2024010140A (es) Nuevos metodos.
JP2016106150A5 (enExample)
JP2016508134A5 (enExample)
JP2015500225A5 (enExample)
JP2016147915A5 (enExample)
RU2018105655A (ru) Комбинированная терапия с применением липосомального иринотекана и ингибитора parp для лечения рака
JP2016528162A5 (enExample)
MX395482B (es) Compuestos antiproliferativos y metodos de uso de los mismos
RU2013156378A (ru) 4-амино-5-фтор-3-[6-(4-метилпиперазин-1-ил)-1н-бензимидазол-2-ил]-1н-хинолин-2-он для применения при лечении аденокистозной карциномы
JP2016536286A5 (enExample)
JP2015512398A5 (enExample)
ME02470B (me) Nanočesтice nabijene sa hemoterapeutskim anтitumorskim lekom
MX392408B (es) Tratamiento de cáncer gástrico usando terapias de combinación que comprenden irinotecán liposómico oxaliplatino, 5-fluoruracilo (y leucovorina).
MX382754B (es) Terapias combinadas para tratar el cancer.
MX2016011333A (es) Sistemas de administracion de farmaco y metodo para el tratamiento de cancer de vejiga con gemcitabina.
JP2019505529A5 (enExample)
JP2019535760A5 (ja) ガボキサドールを用いた注意欠陥多動性障害(adhd)の治療方法
JP2016513703A5 (enExample)
JP2015502926A5 (enExample)
RU2015145997A (ru) Противоопухолевое лекарственное средство, включающее низкодозированный гидрохлорида иринотекана гидрат
PH12018502422A1 (en) Nanoliposomal irinotecan for use in treating small cell lung cancer