JP2019518568A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019518568A5 JP2019518568A5 JP2018567587A JP2018567587A JP2019518568A5 JP 2019518568 A5 JP2019518568 A5 JP 2019518568A5 JP 2018567587 A JP2018567587 A JP 2018567587A JP 2018567587 A JP2018567587 A JP 2018567587A JP 2019518568 A5 JP2019518568 A5 JP 2019518568A5
- Authority
- JP
- Japan
- Prior art keywords
- implant
- fibers
- poly
- lactide
- glycolide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 claims 36
- 239000000835 fiber Substances 0.000 claims 16
- 229920001577 copolymer Polymers 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 8
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 7
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical group CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 7
- 239000011173 biocomposite Substances 0.000 claims 6
- -1 etc.) Chemical compound 0.000 claims 6
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 6
- 239000011707 mineral Substances 0.000 claims 6
- 229920000747 poly(lactic acid) Polymers 0.000 claims 5
- 239000012783 reinforcing fiber Substances 0.000 claims 5
- OZJPLYNZGCXSJM-UHFFFAOYSA-N 5-valerolactone Chemical compound O=C1CCCCO1 OZJPLYNZGCXSJM-UHFFFAOYSA-N 0.000 claims 4
- 229920000331 Polyhydroxybutyrate Polymers 0.000 claims 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- 239000005015 poly(hydroxybutyrate) Substances 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 claims 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 3
- 238000002513 implantation Methods 0.000 claims 3
- 239000002557 mineral fiber Substances 0.000 claims 3
- 229920001432 poly(L-lactide) Polymers 0.000 claims 3
- 230000003014 reinforcing effect Effects 0.000 claims 3
- 229920001897 terpolymer Polymers 0.000 claims 3
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims 3
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims 2
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 229920001710 Polyorthoester Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 239000001913 cellulose Chemical class 0.000 claims 2
- 229920002678 cellulose Chemical class 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- 229920000117 poly(dioxanone) Polymers 0.000 claims 2
- 239000002745 poly(ortho ester) Substances 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 239000004814 polyurethane Substances 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- VKSWWACDZPRJAP-UHFFFAOYSA-N 1,3-dioxepan-2-one Chemical compound O=C1OCCCCO1 VKSWWACDZPRJAP-UHFFFAOYSA-N 0.000 claims 1
- SJDLIJNQXLJBBE-UHFFFAOYSA-N 1,4-dioxepan-2-one Chemical compound O=C1COCCCO1 SJDLIJNQXLJBBE-UHFFFAOYSA-N 0.000 claims 1
- AOLNDUQWRUPYGE-UHFFFAOYSA-N 1,4-dioxepan-5-one Chemical compound O=C1CCOCCO1 AOLNDUQWRUPYGE-UHFFFAOYSA-N 0.000 claims 1
- FMHKPLXYWVCLME-UHFFFAOYSA-N 4-hydroxy-valeric acid Chemical compound CC(O)CCC(O)=O FMHKPLXYWVCLME-UHFFFAOYSA-N 0.000 claims 1
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 1
- 229930185605 Bisphenol Natural products 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 229920001651 Cyanoacrylate Polymers 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229920002732 Polyanhydride Polymers 0.000 claims 1
- 239000004642 Polyimide Substances 0.000 claims 1
- 229920000388 Polyphosphate Polymers 0.000 claims 1
- 229910004298 SiO 2 Inorganic materials 0.000 claims 1
- 229920002472 Starch Chemical class 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims 1
- 238000013459 approach Methods 0.000 claims 1
- 238000005452 bending Methods 0.000 claims 1
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 229960005188 collagen Drugs 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 101150062058 gpa-8 gene Proteins 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 210000003127 knee Anatomy 0.000 claims 1
- 239000001630 malic acid Substances 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000000399 orthopedic effect Effects 0.000 claims 1
- 235000006408 oxalic acid Nutrition 0.000 claims 1
- 229920001308 poly(aminoacid) Polymers 0.000 claims 1
- 239000005014 poly(hydroxyalkanoate) Chemical class 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 229920000515 polycarbonate Polymers 0.000 claims 1
- 239000004417 polycarbonate Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920006149 polyester-amide block copolymer Polymers 0.000 claims 1
- 229920002643 polyglutamic acid Polymers 0.000 claims 1
- 229920000903 polyhydroxyalkanoate Chemical class 0.000 claims 1
- 229920001721 polyimide Polymers 0.000 claims 1
- 239000001205 polyphosphate Substances 0.000 claims 1
- 235000011176 polyphosphates Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000008107 starch Chemical class 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 210000002435 tendon Anatomy 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662354823P | 2016-06-27 | 2016-06-27 | |
| US62/354,823 | 2016-06-27 | ||
| PCT/IL2017/050707 WO2018002917A1 (en) | 2016-06-27 | 2017-06-26 | Fiber reinforced biocomposite medical implants with high mineral content |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019518568A JP2019518568A (ja) | 2019-07-04 |
| JP2019518568A5 true JP2019518568A5 (enExample) | 2020-07-30 |
Family
ID=60786965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018567587A Pending JP2019518568A (ja) | 2016-06-27 | 2017-06-26 | 高い鉱物含有量を有する繊維強化バイオ複合材料の医療用インプラント |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11491264B2 (enExample) |
| EP (1) | EP3474913B1 (enExample) |
| JP (1) | JP2019518568A (enExample) |
| KR (1) | KR102456201B1 (enExample) |
| CN (1) | CN109641081A (enExample) |
| AU (1) | AU2017287968B2 (enExample) |
| CA (1) | CA3028635A1 (enExample) |
| FI (1) | FI3474913T3 (enExample) |
| IL (1) | IL263882B2 (enExample) |
| SG (2) | SG11201811090WA (enExample) |
| WO (1) | WO2018002917A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2014190289A2 (en) | 2013-05-23 | 2014-11-27 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2012054742A2 (en) | 2010-10-20 | 2012-04-26 | BIOS2 Medical, Inc. | Implantable polymer for bone and vascular lesions |
| EP2819620A4 (en) | 2012-02-29 | 2015-11-04 | 206 Ortho Inc | METHOD AND APPARATUS FOR TREATING BONE FRACTURES, INCLUDING THE USE OF COMPOSITE IMPLANTS |
| KR102504497B1 (ko) | 2014-09-07 | 2023-02-27 | 오씨오 리미티드 | 이방성 생체복합재료 물질, 이를 포함하는 의학적 이식물 및 이의 치료방법 |
| CN107106210B (zh) | 2014-12-26 | 2021-05-04 | 奥西奥有限公司 | 连续纤维增强的生物复合材料医用植入物 |
| US11491264B2 (en) | 2016-06-27 | 2022-11-08 | Ossio Ltd. | Fiber reinforced biocomposite medical implants with high mineral content |
| US10722280B2 (en) * | 2017-03-29 | 2020-07-28 | Bone Solutions, Inc. | Implant of osteostimulative material |
| US11540866B2 (en) * | 2017-03-29 | 2023-01-03 | Bone Solutions, Inc. | Implant of osteostimulative material |
| CN111110404B (zh) * | 2020-01-10 | 2021-04-23 | 苏州诺普再生医学有限公司 | 一种3d打印的多结构骨复合支架 |
| GB2597063A (en) * | 2020-07-09 | 2022-01-19 | Invibio Device Component Mfg Limited | Composite materials |
| CN112370634B (zh) * | 2020-11-03 | 2023-04-25 | 山东华安生物科技有限公司 | 一种复合管及其制备方法和应用 |
| AU2022316483A1 (en) * | 2021-07-19 | 2024-01-25 | Ossio Ltd. | Fiber-reinforced biocomposite medical implants with deformable protrusions and methods of use thereof |
| IL294542A (en) | 2021-07-19 | 2023-02-01 | Ossio Ltd | A device with a tube for inserting implants with an adjustable insertion depth |
| EP4479105A1 (en) * | 2022-02-16 | 2024-12-25 | Purac Biochem B.V. | Biocompatible and resorbable composite material and method for obtaining such |
Family Cites Families (101)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4750905A (en) | 1985-07-10 | 1988-06-14 | Harrington Arthritis Research Center | Beam construction and method |
| US4978360A (en) | 1986-03-03 | 1990-12-18 | Zimmer, Inc. | Method of manufacturing a composite implant prosthesis |
| US5192330A (en) | 1987-01-20 | 1993-03-09 | Smith & Nephew Richards, Inc. | Orthopedic device of biocompatible polymer with oriented fiber reinforcement |
| US5064439A (en) | 1987-01-20 | 1991-11-12 | Richards Medical Company | Orthopedic device of biocompatible polymer with oriented fiber reinforcement |
| DE3734108A1 (de) | 1987-10-06 | 1989-04-20 | Mecron Med Prod Gmbh | Marknagel fuer die behandlung von knochenbruechen |
| US4911718A (en) | 1988-06-10 | 1990-03-27 | University Of Medicine & Dentistry Of N.J. | Functional and biocompatible intervertebral disc spacer |
| DE3831657A1 (de) * | 1988-09-17 | 1990-03-22 | Boehringer Ingelheim Kg | Vorrichtung zur osteosynthese und verfahren zu ihrer herstellung |
| US6171338B1 (en) | 1988-11-10 | 2001-01-09 | Biocon, Oy | Biodegradable surgical implants and devices |
| US5209888A (en) | 1988-12-16 | 1993-05-11 | Fukuvi Chemical Industry Co., Ltd. | Method for producing frp screw-like fastening elements |
| US5522817A (en) | 1989-03-31 | 1996-06-04 | United States Surgical Corporation | Absorbable surgical fastener with bone penetrating elements |
| EP0442256B1 (de) | 1990-02-14 | 1996-05-29 | MAN Ceramics GmbH | Knochenimplantat |
| US5181930A (en) | 1991-04-10 | 1993-01-26 | Pfizer Hospital Products Group, Inc. | Composite orthopedic implant |
| US5312669A (en) | 1992-01-03 | 1994-05-17 | Becker Orthopedic Appliance Company | Thermoplastic composite reinforcement and method for orthotic, prosthetic and other devices |
| FR2709949B1 (fr) | 1993-09-14 | 1995-10-13 | Commissariat Energie Atomique | Prothèse de disque intervertébral. |
| US5522904A (en) | 1993-10-13 | 1996-06-04 | Hercules Incorporated | Composite femoral implant having increased neck strength |
| US5507814A (en) | 1994-03-30 | 1996-04-16 | Northwestern University | Orthopedic implant with self-reinforced mantle |
| WO1996009014A1 (en) | 1994-09-20 | 1996-03-28 | Smith & Nephew Richards, Inc. | Composite threaded component and method of manufacture |
| EP0795336B1 (en) | 1995-09-14 | 2003-06-11 | Takiron Co. Ltd. | Osteosynthetic material, composited implant material, and process for preparing the same |
| US6299649B1 (en) | 1996-06-22 | 2001-10-09 | Fu-Kuo Chang | Unbalanced prosthetic device for providing side-dependent twisting-rotational axial-loading coupling |
| US6602293B1 (en) | 1996-11-01 | 2003-08-05 | The Johns Hopkins University | Polymeric composite orthopedic implant |
| US5728098A (en) | 1996-11-07 | 1998-03-17 | Sdgi Holdings, Inc. | Multi-angle bone screw assembly using shape-memory technology |
| US6004650A (en) | 1996-12-31 | 1999-12-21 | Owens Corning Fiberglas Technology, Inc. | Fiber reinforced composite part and method of making same |
| DE69840171D1 (de) | 1997-05-30 | 2008-12-11 | Osteobiologics Inc | Faserverstärkte,poröse,biologisch abbaubare implantatvorrichtung |
| US7541049B1 (en) | 1997-09-02 | 2009-06-02 | Linvatec Biomaterials Oy | Bioactive and biodegradable composites of polymers and ceramics or glasses and method to manufacture such composites |
| CN1089009C (zh) | 1997-10-22 | 2002-08-14 | 刘建宇 | 高分子人体植入物及其制备方法产品和用途 |
| DE19823737C2 (de) | 1998-05-27 | 2003-05-15 | Sepitec Foundation Vaduz | Verbundwerkstoff aus Polymer- oder Keramikmaterialien |
| US6200321B1 (en) | 1998-09-10 | 2001-03-13 | Hand Innovations, Inc. | Fracture fixation system |
| US6352667B1 (en) * | 1999-08-24 | 2002-03-05 | Absorbable Polymer Technologies, Inc. | Method of making biodegradable polymeric implants |
| CA2389627A1 (en) | 1999-11-01 | 2001-05-10 | Osteobiologics, Inc. | Biodegradable polymer/ceramic implant material with bimodal degradation profile |
| US7947069B2 (en) | 1999-11-24 | 2011-05-24 | University Of Washington | Medical devices comprising small fiber biomaterials, and methods of use |
| US6306140B1 (en) | 2001-01-17 | 2001-10-23 | Synthes (Usa) | Bone screw |
| CN1174716C (zh) | 2001-02-28 | 2004-11-10 | 上海市黄浦区中心医院 | 外覆生物膜的多层结构人工韧带 |
| KR100439871B1 (ko) * | 2001-04-28 | 2004-07-12 | 주식회사 메타바이오메드 | 나노섬유로 강화된 의료기구용 복합재료 및 그의 제조방법 |
| US6471707B1 (en) | 2001-05-11 | 2002-10-29 | Biomet | Bone screw having bioresorbable proximal shaft portion |
| US6916321B2 (en) | 2001-09-28 | 2005-07-12 | Ethicon, Inc. | Self-tapping resorbable two-piece bone screw |
| US6921402B2 (en) | 2001-12-27 | 2005-07-26 | Ethicon, Inc. | Polymer-based orthopedic screw and driver system with increased insertion torque tolerance and associated method for making and using same |
| ATE473695T1 (de) | 2002-02-25 | 2010-07-15 | Jeffrey E Yeung | Spreizbares befestigungselement mit zusammendrückbaren greifelementen |
| AU2003304348A1 (en) | 2002-03-15 | 2005-02-04 | The Trustees Of The University Of Pennsylvania | Fibrous composite for tissue engineering |
| SE523288C2 (sv) | 2002-07-19 | 2004-04-06 | Astra Tech Ab | Ett implantat och ett förfarande för behandling av en implantatyta |
| JP2004160157A (ja) | 2002-09-24 | 2004-06-10 | Unitika Ltd | 骨修復材料およびその製造方法 |
| GB0302026D0 (en) | 2003-01-29 | 2003-02-26 | Biocomposites Ltd | Bioabsorbable implant |
| CN1565396A (zh) | 2003-06-09 | 2005-01-19 | 上海上材生物材料有限公司 | 一种人工椎体 |
| CA2527778C (en) | 2003-06-13 | 2011-11-08 | Tyco Healthcare Group Lp | Multiple member interconnect for surgical instrument and absorbable screw fastener |
| US7153325B2 (en) | 2003-08-01 | 2006-12-26 | Ultra-Kinetics, Inc. | Prosthetic intervertebral disc and methods for using the same |
| JP5448297B2 (ja) | 2003-10-16 | 2014-03-19 | テクコム・グループ・リミテッド・ライアビリティ・カンパニー | 低減した血中応答を有する低減可消化炭水化物食物 |
| CN101420970A (zh) | 2003-11-20 | 2009-04-29 | 血管技术国际股份公司 | 可植入传感器和可植入泵以及抗瘢痕形成剂 |
| EP1537839A1 (en) | 2003-12-02 | 2005-06-08 | Dr. h. c. Robert Mathys Foundation | Prosthetic device for cartilage repair |
| AU2005211722B2 (en) | 2004-02-05 | 2011-06-02 | Osteobiologics, Inc. | Absorbable orthopedic implants |
| JP4340705B2 (ja) | 2004-04-26 | 2009-10-07 | ハウメディカ・オステオニクス・コーポレイション | 無血管性半月板の修復と再生用ステント |
| CN1299654C (zh) | 2004-06-24 | 2007-02-14 | 上海交通大学 | 全髋股骨头假体 |
| US8702716B1 (en) | 2009-09-21 | 2014-04-22 | Reva Medical Inc. | Devices, compositions and methods for bone and tissue augmentation |
| DE602005020642D1 (de) | 2004-08-13 | 2010-05-27 | Setagon Inc | Herstellungsverfahren für medizinprodukte mit nanoporösen schichten |
| US20060095134A1 (en) | 2004-10-28 | 2006-05-04 | Sdgi Holdings, Inc. | Materials, devices and methods for implantation of transformable implants |
| AU2005311977A1 (en) | 2004-11-30 | 2006-06-08 | Osteobiologics, Inc. | Implants and delivery system for treating defects in articulating surfaces |
| US8535722B2 (en) | 2005-03-16 | 2013-09-17 | North Carolina State University | Functionally graded biocompatible coating and coated implant |
| FI20055194A7 (fi) | 2005-04-27 | 2006-10-28 | Bioretec Oy | Bioabsorboituva ja bioaktiivinen komposiittimateriaali ja menetelmä komposiitin valmistamiseksi |
| US8992622B2 (en) | 2005-05-06 | 2015-03-31 | Titan Spine, Llc | Interbody spinal implant having a roughened surface topography |
| US20070150059A1 (en) | 2005-12-22 | 2007-06-28 | Depuy Spine, Inc. | Methods and devices for intervertebral augmentation using injectable formulations and enclosures |
| US20070270969A1 (en) | 2006-05-17 | 2007-11-22 | Schmid Steven R | Welded-woven materials |
| FI124017B (fi) | 2006-06-30 | 2014-01-31 | Stick Tech Oy | Kovettavat kuitulujitetut komposiitit ja menetelmä aplikaatio-orientuneiden kuitulujitettujen komposiittien valmistamiseksi |
| WO2008095046A2 (en) | 2007-01-30 | 2008-08-07 | Loma Vista Medical, Inc., | Biological navigation device |
| FI20075246A7 (fi) | 2007-04-12 | 2009-01-30 | Bioretec Oy | Lääketieteellinen väline |
| DE102007020951A1 (de) * | 2007-05-04 | 2008-11-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren und Vorrichtung zur Reinigung eines resorbierbaren Polyesters |
| DE102008028738A1 (de) | 2007-06-06 | 2008-12-11 | Innotere Gmbh | Implantatmaterial auf Basis eines hydraulischen Zements sowie dessen Verwendung |
| FR2918081B1 (fr) | 2007-06-27 | 2009-09-18 | Cabinet Hecke Sa | Procede d'impregnation de fibres continues par une matrice polymerique composite renfermant un polymere thermoplastique |
| JP5179124B2 (ja) | 2007-09-06 | 2013-04-10 | 矢橋工業株式会社 | 骨再生誘導膜、およびその製造方法 |
| US7998499B2 (en) | 2007-10-25 | 2011-08-16 | Collagen Matrix, Inc. | Calcium-containing bone implants |
| WO2009117737A2 (en) | 2008-03-21 | 2009-09-24 | Biomimedica, Inc | Methods, devices and compositions for adhering hydrated polymer implants to bone |
| WO2010000844A1 (en) | 2008-07-04 | 2010-01-07 | Dr. H.C. Robert Mathys Stiftung | Implant device |
| AU2009282095B2 (en) | 2008-08-11 | 2015-11-26 | Fibralign Corp. | Biocomposites and methods of making the same |
| US20100168798A1 (en) | 2008-12-30 | 2010-07-01 | Clineff Theodore D | Bioactive composites of polymer and glass and method for making same |
| US9456890B2 (en) | 2009-01-15 | 2016-10-04 | The Curators Of The University Of Missouri | Scaffold for bone and tissue repair in mammals |
| EP3251618B8 (en) | 2009-01-16 | 2019-11-13 | Carbofix Orthopedics Ltd. | Composite material bone implant |
| FI20095084A0 (fi) | 2009-01-30 | 2009-01-30 | Pekka Vallittu | Komposiitti ja sen käyttö |
| EP2243749B1 (en) * | 2009-04-23 | 2015-04-08 | PURAC Biochem BV | Resorbable and biocompatible fibre glass compositions and their uses |
| PL2243500T3 (pl) | 2009-04-23 | 2012-06-29 | Purac Biochem Bv | Biozgodny kompozyt i jego zastosowanie |
| WO2010128039A1 (en) | 2009-05-07 | 2010-11-11 | Dsm Ip Assets B.V. | Biodegradable composite comprising a biodegradable polymer and a glass fiber |
| US20110098826A1 (en) | 2009-10-28 | 2011-04-28 | The Trustees Of The University Of Pennsylvania | Disc-Like Angle-Ply Structures for Intervertebral Disc Tissue Engineering and Replacement |
| US10154867B2 (en) | 2010-06-07 | 2018-12-18 | Carbofix In Orthopedics Llc | Multi-layer composite material bone screw |
| US20120040137A1 (en) | 2010-07-27 | 2012-02-16 | Arsenal Medical | Fiber composite structure |
| CN101942709B (zh) | 2010-09-26 | 2012-01-04 | 东华大学 | 一种含多壁碳纳米管的cs/pva 复合纳米纤维及其制备方法 |
| US9186302B2 (en) * | 2010-10-29 | 2015-11-17 | Curators Of The University Of Missouri | Biomaterial compositions |
| TWI494076B (zh) | 2011-04-18 | 2015-08-01 | Univ Nat Central | 醫療用鑽頭 |
| JP6055962B2 (ja) | 2011-07-13 | 2017-01-11 | キャサリン キャドレル | 骨肉インプラント合成部材およびその製造方法 |
| WO2013116624A1 (en) | 2012-02-03 | 2013-08-08 | The Trustees Of The University Of Pennsylvania | Aligned fibrous materials with spatially varying fiber orientation and related methods |
| US9090029B2 (en) | 2012-02-06 | 2015-07-28 | Warsaw Orthopedic, Inc. | Pultrusion process for preparing composites having low percentage of fibers and articles made from same |
| CN104245001B (zh) * | 2012-02-10 | 2017-06-09 | 新特斯有限责任公司 | 多孔植入材料和相关方法 |
| WO2013126562A1 (en) | 2012-02-21 | 2013-08-29 | Thierry Giorno | Plga/ha hydroxyapatite composite bone grafts and method of making |
| US8735504B2 (en) * | 2012-05-02 | 2014-05-27 | Warsaw Orthopedic, Inc. | Methods for preparing polymers having low residual monomer content |
| US20130317555A1 (en) | 2012-05-22 | 2013-11-28 | Benvenue Medical, Inc. | Implant and system for bone repair |
| ES2582610T3 (es) | 2012-11-09 | 2016-09-14 | Karl Leibinger Medizintechnik Gmbh & Co. Kg | Implante óseo de al menos dos materiales distintos reabsorbibles y biodegradables que pueden combinarse como material híbrido o compuesto |
| JP6415040B2 (ja) | 2013-11-29 | 2018-10-31 | キヤノン株式会社 | 画像処理装置、画像処理方法、及びプログラム |
| US9179541B1 (en) | 2014-07-10 | 2015-11-03 | International Business Machines Corporation | Surface-mount connector structure for embedded optical and electrical traces |
| KR102504497B1 (ko) * | 2014-09-07 | 2023-02-27 | 오씨오 리미티드 | 이방성 생체복합재료 물질, 이를 포함하는 의학적 이식물 및 이의 치료방법 |
| CN107106210B (zh) | 2014-12-26 | 2021-05-04 | 奥西奥有限公司 | 连续纤维增强的生物复合材料医用植入物 |
| US10617458B2 (en) | 2015-12-23 | 2020-04-14 | Carbofix In Orthopedics Llc | Multi-layer composite material bone screw |
| WO2017155956A1 (en) | 2016-03-07 | 2017-09-14 | Ossio Ltd | Surface treated biocomposite material, medical implants comprising same and methods of treatment thereof |
| US11491264B2 (en) | 2016-06-27 | 2022-11-08 | Ossio Ltd. | Fiber reinforced biocomposite medical implants with high mineral content |
| EP3320877B1 (de) | 2016-11-14 | 2021-05-26 | Andreas Schwitalla | Implantat aus faserverstärktem kunststoff |
| EP3762048B1 (en) * | 2018-03-06 | 2023-12-06 | DSM IP Assets B.V. | Osteoconductive fibers, medical implant comprising such osteoconductive fibers, and methods of making |
| US11896736B2 (en) * | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
-
2017
- 2017-06-26 US US16/311,784 patent/US11491264B2/en active Active
- 2017-06-26 KR KR1020197001863A patent/KR102456201B1/ko active Active
- 2017-06-26 CN CN201780053086.6A patent/CN109641081A/zh active Pending
- 2017-06-26 CA CA3028635A patent/CA3028635A1/en active Pending
- 2017-06-26 AU AU2017287968A patent/AU2017287968B2/en active Active
- 2017-06-26 SG SG11201811090WA patent/SG11201811090WA/en unknown
- 2017-06-26 EP EP17819487.4A patent/EP3474913B1/en active Active
- 2017-06-26 JP JP2018567587A patent/JP2019518568A/ja active Pending
- 2017-06-26 FI FIEP17819487.4T patent/FI3474913T3/fi active
- 2017-06-26 IL IL263882A patent/IL263882B2/en unknown
- 2017-06-26 WO PCT/IL2017/050707 patent/WO2018002917A1/en not_active Ceased
- 2017-06-27 SG SG10201913457VA patent/SG10201913457VA/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019518568A5 (enExample) | ||
| JP7430393B2 (ja) | ネジを切った繊維強化バイオ複合材料インプラント | |
| JP2017527341A5 (enExample) | ||
| JP6822954B2 (ja) | 連続繊維で補強されたバイオコンポジットの医療用インプラント | |
| JP2017538483A5 (enExample) | ||
| CN106687077B (zh) | 各向异性生物复合材料、包含各向异性生物复合材料的医疗植入物及其治疗方法 | |
| KR102456201B1 (ko) | 높은 광물 함량을 갖는 섬유 강화된 생체복합재료 의료용 임플란트 | |
| CN111629694B (zh) | 纤维束增强的生物复合材料医用植入物 | |
| Naseem et al. | Strategies for enhancing polyester-based materials for bone fixation applications | |
| JP2012524705A5 (enExample) | ||
| US20130309275A1 (en) | Resorbable Bioceramic Compositions of Poly-4-Hydroxybutyrate and Copolymers | |
| AU2012360738A1 (en) | Composite containing polymer and additive as well as its use | |
| Brown et al. | Development of bioresorbable polymers in orthopaedics | |
| HK40004466A (en) | Fiber reinforced biocomposite medical implants with high mineral content | |
| Saikku-Bäckström | Biodegradable self-reinforced polylactic acid stereocopolymer implants in the fixation of diaphyseal osteotomies and fractures: An experimental and clinical study |