JP2017538483A5 - - Google Patents
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- JP2017538483A5 JP2017538483A5 JP2017527796A JP2017527796A JP2017538483A5 JP 2017538483 A5 JP2017538483 A5 JP 2017538483A5 JP 2017527796 A JP2017527796 A JP 2017527796A JP 2017527796 A JP2017527796 A JP 2017527796A JP 2017538483 A5 JP2017538483 A5 JP 2017538483A5
- Authority
- JP
- Japan
- Prior art keywords
- fibers
- copolymer
- range
- poly
- implant according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000835 fiber Substances 0.000 claims 26
- 239000007943 implant Substances 0.000 claims 25
- 229920001577 copolymer Polymers 0.000 claims 15
- 229920000642 polymer Polymers 0.000 claims 12
- 239000011173 biocomposite Substances 0.000 claims 8
- 229920001432 poly(L-lactide) Polymers 0.000 claims 8
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 7
- 239000002131 composite material Substances 0.000 claims 7
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical group CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 7
- 239000012783 reinforcing fiber Substances 0.000 claims 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 6
- RBMHUYBJIYNRLY-UHFFFAOYSA-N 2-[(1-carboxy-1-hydroxyethyl)-hydroxyphosphoryl]-2-hydroxypropanoic acid Chemical compound OC(=O)C(O)(C)P(O)(=O)C(C)(O)C(O)=O RBMHUYBJIYNRLY-UHFFFAOYSA-N 0.000 claims 5
- 239000011159 matrix material Substances 0.000 claims 5
- 229920001434 poly(D-lactide) Polymers 0.000 claims 5
- 229920000747 poly(lactic acid) Polymers 0.000 claims 5
- OZJPLYNZGCXSJM-UHFFFAOYSA-N 5-valerolactone Chemical compound O=C1CCCCO1 OZJPLYNZGCXSJM-UHFFFAOYSA-N 0.000 claims 4
- 229920000331 Polyhydroxybutyrate Polymers 0.000 claims 4
- -1 etc.) Chemical compound 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000005015 poly(hydroxybutyrate) Substances 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 3
- 229920000954 Polyglycolide Polymers 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 3
- 239000011707 mineral Substances 0.000 claims 3
- 229920001610 polycaprolactone Polymers 0.000 claims 3
- 230000002787 reinforcement Effects 0.000 claims 3
- 239000000377 silicon dioxide Substances 0.000 claims 3
- 229920001897 terpolymer Polymers 0.000 claims 3
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims 2
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 229910004298 SiO 2 Inorganic materials 0.000 claims 2
- 229920002988 biodegradable polymer Polymers 0.000 claims 2
- 239000004621 biodegradable polymer Substances 0.000 claims 2
- 239000001913 cellulose Chemical class 0.000 claims 2
- 229920002678 cellulose Chemical class 0.000 claims 2
- 235000010980 cellulose Nutrition 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229920000117 poly(dioxanone) Polymers 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 239000004814 polyurethane Substances 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims 2
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- VKSWWACDZPRJAP-UHFFFAOYSA-N 1,3-dioxepan-2-one Chemical compound O=C1OCCCCO1 VKSWWACDZPRJAP-UHFFFAOYSA-N 0.000 claims 1
- SJDLIJNQXLJBBE-UHFFFAOYSA-N 1,4-dioxepan-2-one Chemical compound O=C1COCCCO1 SJDLIJNQXLJBBE-UHFFFAOYSA-N 0.000 claims 1
- AOLNDUQWRUPYGE-UHFFFAOYSA-N 1,4-dioxepan-5-one Chemical compound O=C1CCOCCO1 AOLNDUQWRUPYGE-UHFFFAOYSA-N 0.000 claims 1
- IJVRPNIWWODHHA-UHFFFAOYSA-N 2-cyanoprop-2-enoic acid Chemical compound OC(=O)C(=C)C#N IJVRPNIWWODHHA-UHFFFAOYSA-N 0.000 claims 1
- ALRHLSYJTWAHJZ-UHFFFAOYSA-M 3-hydroxypropionate Chemical compound OCCC([O-])=O ALRHLSYJTWAHJZ-UHFFFAOYSA-M 0.000 claims 1
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 claims 1
- FMHKPLXYWVCLME-UHFFFAOYSA-N 4-hydroxy-valeric acid Chemical compound CC(O)CCC(O)=O FMHKPLXYWVCLME-UHFFFAOYSA-N 0.000 claims 1
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 1
- 229930185605 Bisphenol Natural products 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 229920002732 Polyanhydride Polymers 0.000 claims 1
- 239000004642 Polyimide Substances 0.000 claims 1
- 229920001710 Polyorthoester Polymers 0.000 claims 1
- 229920000388 Polyphosphate Polymers 0.000 claims 1
- 229920002472 Starch Chemical class 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims 1
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 229940045110 chitosan Drugs 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 229960005188 collagen Drugs 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229920000578 graft copolymer Polymers 0.000 claims 1
- 229920001519 homopolymer Polymers 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 239000001630 malic acid Substances 0.000 claims 1
- 150000002905 orthoesters Chemical class 0.000 claims 1
- 235000006408 oxalic acid Nutrition 0.000 claims 1
- 229920001308 poly(aminoacid) Polymers 0.000 claims 1
- 239000005014 poly(hydroxyalkanoate) Chemical class 0.000 claims 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 claims 1
- 239000002745 poly(ortho ester) Substances 0.000 claims 1
- 229920000515 polycarbonate Polymers 0.000 claims 1
- 239000004417 polycarbonate Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920006149 polyester-amide block copolymer Polymers 0.000 claims 1
- 229920002643 polyglutamic acid Polymers 0.000 claims 1
- 229920000903 polyhydroxyalkanoate Chemical class 0.000 claims 1
- 229920001721 polyimide Polymers 0.000 claims 1
- 239000001205 polyphosphate Substances 0.000 claims 1
- 235000011176 polyphosphates Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 229920005604 random copolymer Polymers 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462096932P | 2014-12-26 | 2014-12-26 | |
| US62/096,932 | 2014-12-26 | ||
| PCT/IB2015/002602 WO2016103049A1 (en) | 2014-12-26 | 2015-12-28 | Continuous-fiber reinforced biocomposite medical implants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538483A JP2017538483A (ja) | 2017-12-28 |
| JP2017538483A5 true JP2017538483A5 (enExample) | 2019-02-07 |
| JP6822954B2 JP6822954B2 (ja) | 2021-01-27 |
Family
ID=56149337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017527796A Active JP6822954B2 (ja) | 2014-12-26 | 2015-12-28 | 連続繊維で補強されたバイオコンポジットの医療用インプラント |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10926004B2 (enExample) |
| EP (2) | EP3628249B1 (enExample) |
| JP (1) | JP6822954B2 (enExample) |
| KR (1) | KR102581716B1 (enExample) |
| CN (1) | CN107106210B (enExample) |
| AU (1) | AU2015370600B2 (enExample) |
| BR (1) | BR112017012508B1 (enExample) |
| CA (1) | CA2971990C (enExample) |
| ES (1) | ES2763928T3 (enExample) |
| FI (1) | FI3628249T3 (enExample) |
| IL (1) | IL253171B (enExample) |
| MX (1) | MX2017008530A (enExample) |
| SG (2) | SG11201702962QA (enExample) |
| WO (1) | WO2016103049A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10525168B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11058796B2 (en) | 2010-10-20 | 2021-07-13 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| EP2629780A4 (en) | 2010-10-20 | 2014-10-01 | 206 Ortho Inc | IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS |
| US10525169B2 (en) | 2010-10-20 | 2020-01-07 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US9320601B2 (en) | 2011-10-20 | 2016-04-26 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| JP2016525379A (ja) | 2013-05-23 | 2016-08-25 | ２０６ オーソ，インコーポレーテッド | 複合材インプラントの提供および使用を含む、骨折を治療するための、ならびに／または、骨を補強および／もしくは増強するための方法および装置 |
| EP3188693B1 (en) | 2014-09-07 | 2020-05-27 | Ossio Ltd. | Anisotropic biocomposite material, medical implants comprising same and methods of treatment thereof |
| CN107106210B (zh) | 2014-12-26 | 2021-05-04 | 奥西奥有限公司 | 连续纤维增强的生物复合材料医用植入物 |
| EP3426312B1 (en) * | 2016-03-07 | 2026-03-25 | Ossio Ltd. | Surface treated biocomposite material, medical implants comprising same and methods of treatment thereof |
| KR102456201B1 (ko) * | 2016-06-27 | 2022-10-19 | 오씨오 리미티드 | 높은 광물 함량을 갖는 섬유 강화된 생체복합재료 의료용 임플란트 |
| US11540866B2 (en) * | 2017-03-29 | 2023-01-03 | Bone Solutions, Inc. | Implant of osteostimulative material |
| US10722280B2 (en) * | 2017-03-29 | 2020-07-28 | Bone Solutions, Inc. | Implant of osteostimulative material |
| FI3678566T3 (fi) * | 2017-09-07 | 2024-11-28 | Ossio Ltd | Kuitulujitettuja kierteitettyjä biokomposiitti-implantteja |
| CN107596429B (zh) * | 2017-09-29 | 2020-09-29 | 南京轩凯生物科技有限公司 | 一种血液蛋白响应型γ-聚谷氨酸水凝胶止血材料及其制备方法和应用 |
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| DE102017009989A1 (de) * | 2017-10-26 | 2019-05-02 | Carl Freudenberg Kg | Biokompatibles Verbundmaterial zum Einbringen in einen menschlichen Körper |
| WO2019123462A1 (en) | 2017-12-20 | 2019-06-27 | Ossio Ltd. | Fiber bundle reinforced biocomposite medical implants |
| EP3813698A4 (en) * | 2018-05-09 | 2022-06-01 | 206 Ortho, Inc. | METHOD AND APPARATUS FOR TREATMENT OF FRACTURES AND/OR FOR STRENGTHENING AND/OR GROWING BONES, INCLUDING THE PROVISION AND USE OF COMPOSITE IMPLANTS, AND NOVEL COMPOSITE STRUCTURES FOR USE FOR MEDICAL AND NON-MEDICAL APPLICATIONS |
| CN108434534B (zh) * | 2018-06-11 | 2020-05-19 | 浙江大学 | 一种具有仿钢筋-混凝土结构的高强度氧化石墨烯/壳聚糖复合接骨钉材料及其制备方法 |
| ES2935496T3 (es) | 2019-08-21 | 2023-03-07 | Bioretec Oy | Material compuesto, implante que lo comprende, uso del material compuesto y método para preparar un dispositivo médico |
| US20210146016A1 (en) | 2019-11-15 | 2021-05-20 | Evonik Operations Gmbh | Fiber reinforced compositions and methods of manufacture for medical device applications |
| GB2597063A (en) * | 2020-07-09 | 2022-01-19 | Invibio Device Component Mfg Limited | Composite materials |
| JP7446965B2 (ja) | 2020-09-29 | 2024-03-11 | グローブライド株式会社 | 脊椎固定具用ロッド |
| US12383246B2 (en) | 2020-10-12 | 2025-08-12 | Abbott Cardiovascular Systems, Inc. | Vessel closure device with improved safety and tract hemostasis |
| CN112370634B (zh) * | 2020-11-03 | 2023-04-25 | 山东华安生物科技有限公司 | 一种复合管及其制备方法和应用 |
| CN113398325B (zh) * | 2021-06-11 | 2023-04-21 | 叶川 | 用于增强螺钉稳定性和诱导骨再生的纤维膜及其制备方法 |
| IL294542B1 (en) | 2021-07-19 | 2026-02-01 | Ossio Ltd | Device with an implant insertion tube with adjustable insertion depth |
| US20250135075A1 (en) * | 2021-07-19 | 2025-05-01 | Ossio Ltd | Fiber-reinforced biocomposite medical implants with deformable protrusions and methods of use thereof |
| JP7626681B2 (ja) * | 2021-08-05 | 2025-02-04 | グローブライド株式会社 | 脊椎固定具用ロッド |
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| WO2023225649A1 (en) * | 2022-05-19 | 2023-11-23 | 206 Ortho, Inc. | Degradable composite and method of fabrication |
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