JP2019516737A5 - - Google Patents
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- Publication number
- JP2019516737A5 JP2019516737A5 JP2018560884A JP2018560884A JP2019516737A5 JP 2019516737 A5 JP2019516737 A5 JP 2019516737A5 JP 2018560884 A JP2018560884 A JP 2018560884A JP 2018560884 A JP2018560884 A JP 2018560884A JP 2019516737 A5 JP2019516737 A5 JP 2019516737A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- amino
- benzenesulfonamide
- thiazol
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021142186A JP2021185189A (ja) | 2016-05-20 | 2021-09-01 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662339773P | 2016-05-20 | 2016-05-20 | |
| US62/339,773 | 2016-05-20 | ||
| US201662432152P | 2016-12-09 | 2016-12-09 | |
| US62/432,152 | 2016-12-09 | ||
| PCT/US2017/033634 WO2017201468A1 (en) | 2016-05-20 | 2017-05-19 | Benzenesulfonamide compounds and their use as therapeutic agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021142186A Division JP2021185189A (ja) | 2016-05-20 | 2021-09-01 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516737A JP2019516737A (ja) | 2019-06-20 |
| JP2019516737A5 true JP2019516737A5 (enExample) | 2020-06-25 |
| JP6938545B2 JP6938545B2 (ja) | 2021-09-22 |
Family
ID=58794232
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560884A Expired - Fee Related JP6938545B2 (ja) | 2016-05-20 | 2017-05-19 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
| JP2021142186A Withdrawn JP2021185189A (ja) | 2016-05-20 | 2021-09-01 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
| JP2023099277A Withdrawn JP2023108032A (ja) | 2016-05-20 | 2023-06-16 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
| JP2025068729A Pending JP2025105687A (ja) | 2016-05-20 | 2025-04-18 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021142186A Withdrawn JP2021185189A (ja) | 2016-05-20 | 2021-09-01 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
| JP2023099277A Withdrawn JP2023108032A (ja) | 2016-05-20 | 2023-06-16 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
| JP2025068729A Pending JP2025105687A (ja) | 2016-05-20 | 2025-04-18 | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US10246453B2 (enExample) |
| EP (1) | EP3458449B1 (enExample) |
| JP (4) | JP6938545B2 (enExample) |
| KR (1) | KR102366077B1 (enExample) |
| CN (1) | CN109526219B (enExample) |
| AU (2) | AU2017268006B2 (enExample) |
| CA (1) | CA3023465C (enExample) |
| CL (1) | CL2018003260A1 (enExample) |
| CO (1) | CO2018012485A2 (enExample) |
| ES (1) | ES3022639T3 (enExample) |
| HR (1) | HRP20250505T1 (enExample) |
| HU (1) | HUE071358T2 (enExample) |
| IL (1) | IL262834B (enExample) |
| MX (1) | MX386471B (enExample) |
| MY (1) | MY199208A (enExample) |
| PH (1) | PH12018502378B1 (enExample) |
| PL (1) | PL3458449T3 (enExample) |
| RS (1) | RS66796B1 (enExample) |
| RU (1) | RU2769827C2 (enExample) |
| SG (2) | SG10201912216VA (enExample) |
| TN (1) | TN2018000385A1 (enExample) |
| WO (1) | WO2017201468A1 (enExample) |
| ZA (1) | ZA201807518B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017201468A1 (en) | 2016-05-20 | 2017-11-23 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| EP3551626B1 (en) | 2016-12-09 | 2023-10-25 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| AU2019285184B2 (en) * | 2018-06-13 | 2023-11-16 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| US10981905B2 (en) | 2018-08-31 | 2021-04-20 | Xenon Pharmaceuticals Inc. | Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents |
| MA53488A (fr) * | 2018-08-31 | 2021-12-08 | Xenon Pharmaceuticals Inc | Composés de sulfonamide substitués par hétéroaryle et leur utilisation en tant qu'inhibiteurs de canaux sodiques |
| US12703680B2 (en) | 2019-11-21 | 2026-08-11 | University Of Utah Research Foundation | TRPV4 receptor ligands |
| JP2023546059A (ja) * | 2020-10-13 | 2023-11-01 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ＮａＶ１．６活性に関連する状態の処置におけるＮａＶ１．６ナトリウムチャネル遮断薬（Ｓ）－４－（（１－ベンジルピロリジン－３－イル）（メチル）アミノ）－２－フルオロ－５－メチル－Ｎ（チアゾール－４－イル）ベンゼンスルホンアミドのシトクロムＰ４５０ ３Ａ４の強力な誘導物質との使用 |
| US20230404913A1 (en) * | 2020-10-13 | 2023-12-21 | Xenon Pharmaceuticals, Inc. | Pharmaceutical formulations for treating diseases associated with voltage-gated sodium channels |
| US20250333404A1 (en) * | 2022-06-02 | 2025-10-30 | Neurocrine Biosciences, Inc. | Deuterated compounds |
| AR133184A1 (es) * | 2023-07-07 | 2025-09-03 | Novartis Ag | Bloqueadores de canales de sodio |
| WO2025024795A1 (en) * | 2023-07-27 | 2025-01-30 | Neurocrine Biosciences, Inc. | Crystalline forms |
| CN122295335A (zh) * | 2023-11-16 | 2026-06-26 | 南京同诺康医药科技有限公司 | Nmt抑制剂及其制备方法和用途 |
| UY41013A (es) | 2023-12-21 | 2025-07-31 | Syngenta Crop Protection Ag | Compuestos de quinazolina pesticidamente activos |
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| US5877193A (en) | 1996-07-19 | 1999-03-02 | Hoffmann-La Roche Inc. | Use of N-(4-aryl-thiazol-2-yl)-sulfonamides |
| AU741482B2 (en) | 1997-05-07 | 2001-11-29 | Allergan Pharmaceuticals International Limited | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors |
| CA2349832A1 (en) | 1999-01-13 | 2000-07-20 | Warner-Lambert Company | Benzenesulfonamide derivatives and their use as mek inhibitors |
| ATE250932T1 (de) | 1999-07-16 | 2003-10-15 | Warner Lambert Co | Verfahren zur behandlung von chronischem schmerz durch verabreichung von einem mek hemmer |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| FR2836917B1 (fr) | 2002-03-11 | 2006-02-24 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif |
| CA2744893A1 (en) | 2002-06-27 | 2004-01-08 | Novo Nordisk A/S | Aryl carbonyl derivatives as glucokinase activators |
| WO2004092123A2 (en) | 2003-04-10 | 2004-10-28 | Microbia, Inc. | Inhibitors of fungal invasion |
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| HU227684B1 (en) | 2003-08-29 | 2011-11-28 | Sanofi Aventis | Adamantane and azabicyclo-octane and nonane derivatives and their use as dpp-iv inhibitors |
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| KR101117931B1 (ko) | 2006-08-15 | 2012-04-12 | 에프. 호프만-라 로슈 아게 | 페닐, 피리딘 및 퀴놀린 유도체 |
| RU2474582C2 (ru) | 2006-10-19 | 2013-02-10 | СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Гетероарильные соединения, их композиции и их применение в качестве ингибиторов протеинкиназы |
| JP5460589B2 (ja) | 2007-07-13 | 2014-04-02 | アイカジェン， インコーポレイテッド | ナトリウムチャネル阻害物質 |
| US8853250B2 (en) | 2007-07-13 | 2014-10-07 | Icagen, Inc. | Sodium channel inhibitors |
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| AU2013334664A1 (en) | 2012-10-26 | 2015-05-07 | Merck Sharp & Dohme Corp. | N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels |
| JP2015535251A (ja) | 2012-10-26 | 2015-12-10 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 電位作動型ナトリウムチャネルにおいて選択的活性を有するベンゾオキサゾリノン化合物 |
| TW201512171A (zh) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | 化學化合物 |
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| WO2017201468A1 (en) | 2016-05-20 | 2017-11-23 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| US10968210B2 (en) | 2016-11-17 | 2021-04-06 | Merck Sharp & Dohme Corp. | Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
| EP3551626B1 (en) | 2016-12-09 | 2023-10-25 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| AU2019285184B2 (en) * | 2018-06-13 | 2023-11-16 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| MA53488A (fr) | 2018-08-31 | 2021-12-08 | Xenon Pharmaceuticals Inc | Composés de sulfonamide substitués par hétéroaryle et leur utilisation en tant qu'inhibiteurs de canaux sodiques |
-
2017
- 2017-05-19 WO PCT/US2017/033634 patent/WO2017201468A1/en not_active Ceased
- 2017-05-19 PH PH1/2018/502378A patent/PH12018502378B1/en unknown
- 2017-05-19 AU AU2017268006A patent/AU2017268006B2/en active Active
- 2017-05-19 TN TNP/2018/000385A patent/TN2018000385A1/en unknown
- 2017-05-19 HR HRP20250505TT patent/HRP20250505T1/hr unknown
- 2017-05-19 PL PL17726487.6T patent/PL3458449T3/pl unknown
- 2017-05-19 ES ES17726487T patent/ES3022639T3/es active Active
- 2017-05-19 CN CN201780042625.6A patent/CN109526219B/zh active Active
- 2017-05-19 RU RU2018145045A patent/RU2769827C2/ru active
- 2017-05-19 SG SG10201912216VA patent/SG10201912216VA/en unknown
- 2017-05-19 KR KR1020187036489A patent/KR102366077B1/ko active Active
- 2017-05-19 HU HUE17726487A patent/HUE071358T2/hu unknown
- 2017-05-19 US US15/600,490 patent/US10246453B2/en active Active
- 2017-05-19 JP JP2018560884A patent/JP6938545B2/ja not_active Expired - Fee Related
- 2017-05-19 EP EP17726487.6A patent/EP3458449B1/en active Active
- 2017-05-19 MX MX2018013985A patent/MX386471B/es unknown
- 2017-05-19 CA CA3023465A patent/CA3023465C/en active Active
- 2017-05-19 RS RS20250475A patent/RS66796B1/sr unknown
- 2017-05-19 SG SG11201809702SA patent/SG11201809702SA/en unknown
- 2017-05-19 MY MYPI2018001969A patent/MY199208A/en unknown
-
2018
- 2018-11-06 IL IL262834A patent/IL262834B/en unknown
- 2018-11-08 ZA ZA2018/07518A patent/ZA201807518B/en unknown
- 2018-11-16 CL CL2018003260A patent/CL2018003260A1/es unknown
- 2018-11-21 CO CONC2018/0012485A patent/CO2018012485A2/es unknown
-
2019
- 2019-02-28 US US16/289,212 patent/US10662184B2/en active Active
-
2020
- 2020-03-17 US US16/821,294 patent/US10815229B1/en active Active
- 2020-07-28 US US16/940,696 patent/US11299490B2/en active Active
-
2021
- 2021-06-08 AU AU2021203771A patent/AU2021203771B2/en active Active
- 2021-09-01 JP JP2021142186A patent/JP2021185189A/ja not_active Withdrawn
-
2023
- 2023-06-16 JP JP2023099277A patent/JP2023108032A/ja not_active Withdrawn
-
2025
- 2025-04-18 JP JP2025068729A patent/JP2025105687A/ja active Pending