JP2015517580A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015517580A5 JP2015517580A5 JP2015514233A JP2015514233A JP2015517580A5 JP 2015517580 A5 JP2015517580 A5 JP 2015517580A5 JP 2015514233 A JP2015514233 A JP 2015514233A JP 2015514233 A JP2015514233 A JP 2015514233A JP 2015517580 A5 JP2015517580 A5 JP 2015517580A5
- Authority
- JP
- Japan
- Prior art keywords
- fluorophenyl
- pyrazolo
- methanone
- hexahydro
- sulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261651669P | 2012-05-25 | 2012-05-25 | |
| US61/651,669 | 2012-05-25 | ||
| US201261691083P | 2012-08-20 | 2012-08-20 | |
| US61/691,083 | 2012-08-20 | ||
| US201261715907P | 2012-10-19 | 2012-10-19 | |
| US61/715,907 | 2012-10-19 | ||
| US201361759520P | 2013-02-01 | 2013-02-01 | |
| US61/759,520 | 2013-02-01 | ||
| US201361781629P | 2013-03-14 | 2013-03-14 | |
| US61/781,629 | 2013-03-14 | ||
| PCT/US2013/042732 WO2013177559A2 (en) | 2012-05-25 | 2013-05-24 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015517580A JP2015517580A (ja) | 2015-06-22 |
| JP2015517580A5 true JP2015517580A5 (enExample) | 2016-06-23 |
| JP6172871B2 JP6172871B2 (ja) | 2017-08-02 |
Family
ID=49624542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514233A Active JP6172871B2 (ja) | 2012-05-25 | 2013-05-24 | ヘテロアリール‐ケトン縮合アザデカリン糖質コルチコイドレセプター調節因子 |
Country Status (24)
| Country | Link |
|---|---|
| EP (6) | EP2854814B1 (enExample) |
| JP (1) | JP6172871B2 (enExample) |
| KR (1) | KR102062640B1 (enExample) |
| CN (1) | CN104619328B (enExample) |
| AU (1) | AU2013266110C1 (enExample) |
| BR (1) | BR112014028857B1 (enExample) |
| CA (1) | CA2872260C (enExample) |
| CL (1) | CL2014003173A1 (enExample) |
| DK (5) | DK3851107T3 (enExample) |
| ES (5) | ES2930298T3 (enExample) |
| FI (1) | FI4119561T3 (enExample) |
| HK (1) | HK1250014B (enExample) |
| IL (1) | IL235868A (enExample) |
| MX (1) | MX365423B (enExample) |
| MY (1) | MY172739A (enExample) |
| NZ (1) | NZ701469A (enExample) |
| PE (1) | PE20150352A1 (enExample) |
| PH (1) | PH12014502584A1 (enExample) |
| PL (5) | PL2854814T3 (enExample) |
| PT (5) | PT4119561T (enExample) |
| RU (1) | RU2639867C2 (enExample) |
| SG (1) | SG11201407682TA (enExample) |
| WO (1) | WO2013177559A2 (enExample) |
| ZA (1) | ZA201408182B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12226412B2 (en) | 2012-05-25 | 2025-02-18 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| MX368167B (es) | 2013-11-25 | 2019-09-23 | Corcept Therapeutics Inc | Moduladores de receptores de glucocorticoides de azadecalina octahidro fusionada. |
| CN107530435A (zh) * | 2015-03-02 | 2018-01-02 | 科赛普特治疗学股份有限公司 | 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤 |
| CN107530339B (zh) | 2015-03-30 | 2021-03-16 | 科赛普特治疗学股份有限公司 | 糖皮质激素受体拮抗剂联合糖皮质激素用于治疗肾上腺功能不全 |
| PH12017502099B1 (en) | 2015-05-18 | 2023-08-30 | Corcept Therapeutics Inc | Methods for diagnosing and assessing treatment for cushing's syndrome |
| MX383318B (es) | 2015-08-13 | 2025-03-13 | Corcept Therapeutics Inc | Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina. |
| JP6847120B2 (ja) * | 2016-03-01 | 2021-03-24 | コーセプト セラピューティクス， インコーポレイテッド | チェックポイントインヒビターを強化するためのグルココルチコイドレセプターモジュレーターの使用 |
| US9943505B2 (en) | 2016-09-09 | 2018-04-17 | Corcept Therapeutics, Inc. | Glucocorticoid receptor modulators to treat pancreatic cancer |
| US10413540B2 (en) | 2017-03-31 | 2019-09-17 | Corcept Therapeutics, Inc. | Glucocorticoid receptor modulators to treat cervical cancer |
| MX393313B (es) | 2017-06-20 | 2025-03-24 | Corcept Therapeutics Inc | Metodos de tratamiento de tumores neuroepiteliales usando moduladores selectivos del receptor de glucocorticoide. |
| ES3038908T3 (en) * | 2018-04-23 | 2025-10-15 | Corcept Therapeutics Inc | Methods of preparing regioselective n-alkyl triazoles |
| WO2020097513A1 (en) * | 2018-11-09 | 2020-05-14 | Corcept Therapeutics Incorporated | Methods for shrinking pituitary tumors |
| WO2020132046A1 (en) | 2018-12-19 | 2020-06-25 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| CN117281790A (zh) | 2018-12-19 | 2023-12-26 | 科塞普特治疗公司 | 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂 |
| AU2019405771B2 (en) * | 2018-12-20 | 2025-02-20 | Corcept Therapeutics Incorporated | Methods for imaging and treatment of somatostatin-receptor positive tumors |
| EP3927345A4 (en) | 2019-02-22 | 2022-12-21 | Corcept Therapeutics Incorporated | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
| US12440487B2 (en) | 2019-10-16 | 2025-10-14 | Corcept Therapeutics Incorporated | Method of normalizing the neutrophil to lymphocyte ratio in cancer patients with a selective glucocorticoid receptor antagonist |
| WO2021119432A1 (en) | 2019-12-11 | 2021-06-17 | Corcept Therapeutics Incorporated | Methods of treating antipsychotic-induced weight gain with miricorilant |
| CA3162636A1 (en) | 2019-12-21 | 2021-06-24 | Andreas G. MORAITIS | Treatment of, and differential diagnosis between, acth-dependent cushing's syndrome and acth-independent cushing's syndrome |
| MX2022009781A (es) * | 2020-02-10 | 2022-09-09 | Corcept Therapeutics Inc | Metodos para estimular una respuesta antitumoral utilizando un modulador selectivo del receptor de glucocorticoides. |
| WO2022134033A1 (en) * | 2020-12-25 | 2022-06-30 | Corcept Therapeutics Incorporated | Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| CN116829556A (zh) * | 2021-02-03 | 2023-09-29 | 江苏恒瑞医药股份有限公司 | 稠合的氮杂三环类衍生物、其制备方法及其在医药上的应用 |
| KR20250073629A (ko) * | 2022-10-06 | 2025-05-27 | 코어셉트 쎄라퓨틱스 인코포레이티드 | 글루코코르티코이드 수용체 조절제의 제형 |
| EP4608402A1 (en) | 2022-10-28 | 2025-09-03 | Corcept Therapeutics Incorporated | Treatments for amyotrophic lateral sclerosis using dazucorilant |
| KR20250144469A (ko) * | 2023-02-17 | 2025-10-10 | 코어셉트 쎄라퓨틱스 인코포레이티드 | 헌팅턴병 및 이의 증상을 치료하기 위한 방법 및 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| GB8828669D0 (en) * | 1988-12-08 | 1989-01-11 | Lilly Industries Ltd | Organic compounds |
| ES2313317T3 (es) | 2004-03-09 | 2009-03-01 | Corcept Therapeutics, Inc. | Moduladores del receptor de glucocorticoides de azadecalina de anillo condensado. |
| US7640389B2 (en) * | 2006-02-28 | 2009-12-29 | Freescale Semiconductor, Inc. | Non-volatile memory having a multiple block erase mode and method therefor |
| EP1932843A1 (en) * | 2006-12-14 | 2008-06-18 | sanofi-aventis | Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals |
| WO2012027702A1 (en) * | 2010-08-27 | 2012-03-01 | Corcept Therapeutics, Inc. | Pyridyl-amine fused azadecalin modulators |
-
2013
- 2013-05-24 RU RU2014152625A patent/RU2639867C2/ru active
- 2013-05-24 EP EP13793417.0A patent/EP2854814B1/en active Active
- 2013-05-24 PT PT221934383T patent/PT4119561T/pt unknown
- 2013-05-24 AU AU2013266110A patent/AU2013266110C1/en active Active
- 2013-05-24 CA CA2872260A patent/CA2872260C/en active Active
- 2013-05-24 ES ES21154665T patent/ES2930298T3/es active Active
- 2013-05-24 PL PL13793417T patent/PL2854814T3/pl unknown
- 2013-05-24 PT PT211546650T patent/PT3851107T/pt unknown
- 2013-05-24 DK DK21154665.0T patent/DK3851107T3/da active
- 2013-05-24 MY MYPI2014003289A patent/MY172739A/en unknown
- 2013-05-24 DK DK13793417.0T patent/DK2854814T3/en active
- 2013-05-24 KR KR1020147036405A patent/KR102062640B1/ko active Active
- 2013-05-24 PT PT191888858T patent/PT3590517T/pt unknown
- 2013-05-24 PE PE2014002054A patent/PE20150352A1/es active IP Right Grant
- 2013-05-24 NZ NZ701469A patent/NZ701469A/en unknown
- 2013-05-24 ES ES22193438T patent/ES2995026T3/es active Active
- 2013-05-24 DK DK19188885.8T patent/DK3590517T3/da active
- 2013-05-24 ES ES13793417.0T patent/ES2665338T3/es active Active
- 2013-05-24 PL PL21154665.0T patent/PL3851107T3/pl unknown
- 2013-05-24 EP EP19188885.8A patent/EP3590517B1/en active Active
- 2013-05-24 JP JP2015514233A patent/JP6172871B2/ja active Active
- 2013-05-24 PL PL19188885T patent/PL3590517T3/pl unknown
- 2013-05-24 EP EP18154256.4A patent/EP3338781B1/en active Active
- 2013-05-24 PT PT181542564T patent/PT3338781T/pt unknown
- 2013-05-24 ES ES18154256T patent/ES2753816T3/es active Active
- 2013-05-24 MX MX2014014239A patent/MX365423B/es active IP Right Grant
- 2013-05-24 PT PT137934170T patent/PT2854814T/pt unknown
- 2013-05-24 FI FIEP22193438.3T patent/FI4119561T3/fi active
- 2013-05-24 DK DK22193438.3T patent/DK4119561T3/da active
- 2013-05-24 EP EP22193438.3A patent/EP4119561B1/en active Active
- 2013-05-24 EP EP24192650.0A patent/EP4434584A3/en active Pending
- 2013-05-24 PL PL18154256T patent/PL3338781T3/pl unknown
- 2013-05-24 CN CN201380039218.1A patent/CN104619328B/zh active Active
- 2013-05-24 PL PL22193438.3T patent/PL4119561T3/pl unknown
- 2013-05-24 ES ES19188885T patent/ES2873949T3/es active Active
- 2013-05-24 EP EP21154665.0A patent/EP3851107B1/en active Active
- 2013-05-24 BR BR112014028857-7A patent/BR112014028857B1/pt active IP Right Grant
- 2013-05-24 SG SG11201407682TA patent/SG11201407682TA/en unknown
- 2013-05-24 DK DK18154256T patent/DK3338781T3/da active
- 2013-05-24 WO PCT/US2013/042732 patent/WO2013177559A2/en not_active Ceased
-
2014
- 2014-11-10 ZA ZA2014/08182A patent/ZA201408182B/en unknown
- 2014-11-19 PH PH12014502584A patent/PH12014502584A1/en unknown
- 2014-11-21 CL CL2014003173A patent/CL2014003173A1/es unknown
- 2014-11-23 IL IL235868A patent/IL235868A/en active IP Right Grant
-
2018
- 2018-07-23 HK HK18109510.2A patent/HK1250014B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015517580A5 (enExample) | ||
| RU2014152625A (ru) | Конденсированные с гетероарилкетонами азадекалины - модуляторы глюкокортикоидных рецепторов | |
| RU2457207C2 (ru) | Активаторы глюкокиназы | |
| JP2010533158A5 (enExample) | ||
| JP2008501673A5 (enExample) | ||
| JP2018535999A5 (enExample) | ||
| RU2018143324A (ru) | Применение 1H-пиразоло[4,3-b]пиридинов в качестве ингибиторов PDE1 | |
| JP2007523905A5 (enExample) | ||
| JP2007523142A5 (enExample) | ||
| JP2009536196A5 (enExample) | ||
| JP2006503009A5 (enExample) | ||
| CA2747419A1 (en) | Sulfonamide derivatives | |
| IL196129A (en) | Human protein tyrosine phosphatase inhibitors, compositions comprising such compounds and uses thereof in the preparation of medicaments for regulating angiogenesis | |
| RU2004121029A (ru) | Производные пиримидина в качестве модуляторов рецептора инсулинподобного фактора роста 1 (igf-1) | |
| JP2013517264A5 (enExample) | ||
| JP2007519735A5 (enExample) | ||
| JP2014518214A5 (enExample) | ||
| HRP20191327T1 (hr) | 4-hidroksi-3-(heteroaril)piridin-2-on apj agonisti za primjenju u liječenju kardiovaskularnih poremećaja | |
| RU2015132181A (ru) | Фтор-[1,3]-оксазины в качестве ингибиторов васе1 | |
| HRP20211960T1 (hr) | Alosterični modulatori nikotinskih acetilcolinskih receptora | |
| JP2017532364A5 (enExample) | ||
| JP2017500364A5 (enExample) | ||
| JP2019516737A5 (enExample) | ||
| JP2014523400A5 (enExample) | ||
| RU2017118562A (ru) | Соединения-антагонисты дофаминового d3-рецептора |