JP2019515643A5 - - Google Patents

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Publication number
JP2019515643A5
JP2019515643A5 JP2018515676A JP2018515676A JP2019515643A5 JP 2019515643 A5 JP2019515643 A5 JP 2019515643A5 JP 2018515676 A JP2018515676 A JP 2018515676A JP 2018515676 A JP2018515676 A JP 2018515676A JP 2019515643 A5 JP2019515643 A5 JP 2019515643A5
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JP
Japan
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JP2018515676A
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English (en)
Japanese (ja)
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JP2019515643A (ja
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Priority claimed from PCT/US2016/053571 external-priority patent/WO2017053886A2/en
Publication of JP2019515643A publication Critical patent/JP2019515643A/ja
Publication of JP2019515643A5 publication Critical patent/JP2019515643A5/ja
Priority to JP2021042947A priority Critical patent/JP7138207B2/ja
Pending legal-status Critical Current

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JP2018515676A 2015-09-23 2016-09-23 幹細胞分化剤のスクリーニング方法 Pending JP2019515643A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021042947A JP7138207B2 (ja) 2015-09-23 2021-01-08 幹細胞分化剤のスクリーニング方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562222713P 2015-09-23 2015-09-23
US62/222,713 2015-09-23
PCT/US2016/053571 WO2017053886A2 (en) 2015-09-23 2016-09-23 Method of screening for agents for differentiating stem cells

Related Child Applications (1)

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JP2021042947A Division JP7138207B2 (ja) 2015-09-23 2021-01-08 幹細胞分化剤のスクリーニング方法

Publications (2)

Publication Number Publication Date
JP2019515643A JP2019515643A (ja) 2019-06-13
JP2019515643A5 true JP2019515643A5 (enExample) 2019-11-07

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JP2018515676A Pending JP2019515643A (ja) 2015-09-23 2016-09-23 幹細胞分化剤のスクリーニング方法
JP2021042947A Active JP7138207B2 (ja) 2015-09-23 2021-01-08 幹細胞分化剤のスクリーニング方法

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JP2021042947A Active JP7138207B2 (ja) 2015-09-23 2021-01-08 幹細胞分化剤のスクリーニング方法

Country Status (8)

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US (2) US11931347B2 (enExample)
EP (1) EP3352566A4 (enExample)
JP (2) JP2019515643A (enExample)
CN (2) CN113527289A (enExample)
AU (2) AU2016326718B2 (enExample)
CA (1) CA2999503A1 (enExample)
IL (3) IL258314B (enExample)
WO (1) WO2017053886A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019515643A (ja) 2015-09-23 2019-06-13 ミネルバ バイオテクノロジーズ コーポレーション 幹細胞分化剤のスクリーニング方法
WO2018064465A1 (en) 2016-09-29 2018-04-05 The Regents Of The University Of California Compounds for increasing neural plasticity
EP3600451B1 (en) * 2017-03-29 2025-12-24 Minerva Biotechnologies Corporation Agents for differentiating stem cells and treating cancer
CN107892690A (zh) * 2017-11-30 2018-04-10 江苏杏睿生物科技有限公司 Fascaplysin的衍生物及制备方法与用途
US20210299109A1 (en) * 2017-12-19 2021-09-30 Minerva Biotechnologies Corporation Agents for treating cancer and methods for identifying said agents
CN107880040A (zh) * 2017-12-22 2018-04-06 中国药科大学 一种四氢β-咔啉类衍生物及其制备方法与用途
JP7770673B2 (ja) 2019-02-27 2025-11-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 脳障害を治療するためのアゼピノ-インドール及び他の複素環化合物
US12104170B2 (en) 2020-06-26 2024-10-01 Minerva Biotechnologies Corporation Methods for deriving dopaminergic neurons from pluripotent stem cells
AU2021297535A1 (en) 2020-06-26 2023-02-16 Minerva Biotechnologies Corporation Anti-NME antibody and method of treating cancer or cancer metastasis
AU2022416279A1 (en) 2021-12-15 2024-07-25 Delix Therapeutics, Inc. Phenoxy and benzyloxy substituted psychoplastogens and uses thereof
WO2023201234A2 (en) 2022-04-12 2023-10-19 Minerva Biotechnologies Corporation Anti-variable muc1* antibodies and uses thereof
CN115521306B (zh) * 2022-09-26 2024-03-26 贵州大学 一种1,2,3,4-四氢-β-咔啉衍生物及其制备方法和应用
CN115594675B (zh) * 2022-11-02 2024-01-30 西安医学院 一种 β-卡巴林-肉桂酸骨架衍生物及制备方法和用途

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2680366B1 (fr) * 1991-08-13 1995-01-20 Adir Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US20030099611A1 (en) * 1995-09-01 2003-05-29 Sara Lavi Manipulation and detection of protein phosphatase 2c-pp2calpha - expression in tumor cells for cancer therapy, prevention and detection
PL329875A1 (en) 1996-05-10 1999-04-12 Icos Corp Derivatives of carbolin
CA2517416A1 (en) * 2003-02-28 2004-09-10 Howard Florey Institute Of Experimental Physiology And Medicine Therapeutic compositions
CN1852974A (zh) * 2003-06-09 2006-10-25 密歇根大学董事会 用于治疗和诊断癌症的组合物和方法
WO2004113300A1 (ja) 2003-06-23 2004-12-29 Ono Pharmaceutical Co., Ltd. 新規三環性複素環化合物
US7855295B2 (en) * 2004-01-23 2010-12-21 Novartis Vaccines And Diagnostics, Inc. Tetrahydrocarboline compounds as anticancer agents
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
EA201200555A1 (ru) * 2004-03-15 2013-01-30 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Производные карболина, полезные в ингибировании ангиогенеза
CA2584412C (en) * 2004-09-14 2017-05-09 Minerva Biotechnologies Corporation Methods for diagnosis and treatment of cancer
ES2720288T3 (es) 2005-03-30 2019-07-19 Minerva Biotechnologies Corp Proliferación de células que expresan MUC1
WO2007076055A2 (en) * 2005-12-22 2007-07-05 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
AU2007317349B2 (en) * 2006-11-03 2011-10-20 Irm Llc Compounds and compositions as protein kinase inhibitors
CN101652469B (zh) * 2006-12-06 2014-04-16 米纳瓦生物技术公司 用于鉴定和操作细胞的方法
WO2009022104A1 (en) * 2007-08-13 2009-02-19 De Montfort University Fascaplysin derivatives and their use in the treatment of cancer
WO2009042815A1 (en) 2007-09-25 2009-04-02 Minerva Biotechnologies Corp. Methods for treatment of cancer
EP2274617A4 (en) * 2008-04-10 2011-11-09 Massachusetts Inst Technology METHOD OF DETECTING AND USING MEDIUM-TREATMENT AID ON CANCER STEM CELLS
WO2009140260A2 (en) 2008-05-13 2009-11-19 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Cancer stem cell immortalization
EP3228629A1 (en) 2010-06-16 2017-10-11 Minerva Biotechnologies Corporation Reprogramming cancer cells
JP2012068225A (ja) 2010-08-25 2012-04-05 Fujifilm Corp 放射線画像撮影用グリッド及びその製造方法
EP2561888A1 (en) 2011-08-23 2013-02-27 Deutsches Krebsforschungszentrum Protein comprising NC-1 for treating angiogenesis-related diseases
WO2013059373A2 (en) * 2011-10-17 2013-04-25 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
US20150224169A1 (en) 2012-09-06 2015-08-13 Mcmaster University Compounds and methods for selectively targeting cancer stem cells
KR20210082547A (ko) * 2013-02-20 2021-07-05 미네르바 바이오테크놀로지 코포레이션 Nme 저해제 및 nme 저해제의 사용 방법
AU2014306778B2 (en) 2013-08-12 2020-10-29 Minerva Biotechnologies Corporation Method for enhancing tumor growth
CN103880841B (zh) 2014-02-20 2016-04-13 南通大学 含有β-咔啉-3-酰亚肼基的HDAC抑制剂及其制备方法和用途
JP2019515643A (ja) 2015-09-23 2019-06-13 ミネルバ バイオテクノロジーズ コーポレーション 幹細胞分化剤のスクリーニング方法

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