JP2019513407A5 - - Google Patents

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JP2019513407A5
JP2019513407A5 JP2018555646A JP2018555646A JP2019513407A5 JP 2019513407 A5 JP2019513407 A5 JP 2019513407A5 JP 2018555646 A JP2018555646 A JP 2018555646A JP 2018555646 A JP2018555646 A JP 2018555646A JP 2019513407 A5 JP2019513407 A5 JP 2019513407A5
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dna
modified
grna
bcl11a gene
gene
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JP2018555646A
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JP6974349B2 (ja
JP2019513407A (ja
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JP2018555646A 2016-04-18 2017-04-18 ヘモグロビン異常症の処置のための材料及び方法 Active JP6974349B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662324024P 2016-04-18 2016-04-18
US62/324,024 2016-04-18
US201662382522P 2016-09-01 2016-09-01
US62/382,522 2016-09-01
US201662429428P 2016-12-02 2016-12-02
US62/429,428 2016-12-02
PCT/IB2017/000577 WO2017182881A2 (en) 2016-04-18 2017-04-18 Materials and methods for treatment of hemoglobinopathies

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JP2019513407A JP2019513407A (ja) 2019-05-30
JP2019513407A5 true JP2019513407A5 (https=) 2020-05-28
JP6974349B2 JP6974349B2 (ja) 2021-12-01

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JP2018555646A Active JP6974349B2 (ja) 2016-04-18 2017-04-18 ヘモグロビン異常症の処置のための材料及び方法

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US (5) US20200330609A1 (https=)
EP (2) EP4424829A3 (https=)
JP (1) JP6974349B2 (https=)
KR (1) KR102351329B1 (https=)
CN (1) CN109715198B (https=)
AU (1) AU2017252023B2 (https=)
BR (1) BR112018071321A2 (https=)
CA (1) CA3021467A1 (https=)
DK (1) DK3445388T3 (https=)
ES (1) ES2979222T3 (https=)
FI (1) FI3445388T3 (https=)
HR (1) HRP20240657T1 (https=)
HU (1) HUE066768T2 (https=)
IL (1) IL262416B2 (https=)
LT (1) LT3445388T (https=)
MA (1) MA71705A (https=)
MD (1) MD3445388T2 (https=)
MX (1) MX2018012729A (https=)
PL (1) PL3445388T3 (https=)
PT (1) PT3445388T (https=)
RS (1) RS65592B1 (https=)
SG (2) SG10202010261YA (https=)
SI (1) SI3445388T1 (https=)
SM (1) SMT202400195T1 (https=)
WO (1) WO2017182881A2 (https=)

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US11566236B2 (en) 2018-02-05 2023-01-31 Vertex Pharmaceuticals Incorporated Materials and methods for treatment of hemoglobinopathies
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CN110117659B (zh) * 2019-06-18 2022-10-11 上海奕谱生物科技有限公司 一种新型的肿瘤标记物stamp-ep10及其应用
CN114364799B (zh) * 2019-08-28 2024-07-19 甘李药业股份有限公司 编辑造血干/祖细胞中bcl11a基因的方法
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US20240245725A1 (en) * 2021-05-13 2024-07-25 The Children's Medical Center Corporation Methods for stratifying subjects for fetal hemoglobin reinduction
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WO2024073751A1 (en) 2022-09-29 2024-04-04 Vor Biopharma Inc. Methods and compositions for gene modification and enrichment
CN115960968A (zh) * 2022-09-30 2023-04-14 珠海横琴爱姆斯坦生物科技有限公司 制备bcl11a红系增强子纯合突变的基因工程多能干细胞的方法
WO2024095213A1 (en) * 2022-11-02 2024-05-10 Incisive Genetics, Inc. Compositions and methods for preventing, ameliorating, or treating sickle cell disease and compositions and methods for disrupting genes and gene segments
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