JPWO2025094917A1 - - Google Patents

Info

Publication number
JPWO2025094917A1
JPWO2025094917A1 JP2025554790A JP2025554790A JPWO2025094917A1 JP WO2025094917 A1 JPWO2025094917 A1 JP WO2025094917A1 JP 2025554790 A JP2025554790 A JP 2025554790A JP 2025554790 A JP2025554790 A JP 2025554790A JP WO2025094917 A1 JPWO2025094917 A1 JP WO2025094917A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025554790A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2025094917A1 publication Critical patent/JPWO2025094917A1/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2025554790A 2023-10-30 2024-10-29 Pending JPWO2025094917A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2023185785 2023-10-30
PCT/JP2024/038444 WO2025094917A1 (ja) 2023-10-30 2024-10-29 Bcl11a遺伝子のエンハンサーの一部又は全部が破壊された造血幹細胞の製造方法、及びその方法に用いるためのキット

Publications (1)

Publication Number Publication Date
JPWO2025094917A1 true JPWO2025094917A1 (https=) 2025-05-08

Family

ID=95582304

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025554790A Pending JPWO2025094917A1 (https=) 2023-10-30 2024-10-29

Country Status (3)

Country Link
JP (1) JPWO2025094917A1 (https=)
CN (1) CN121844044A (https=)
WO (1) WO2025094917A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109554350B (zh) 2012-11-27 2022-09-23 儿童医疗中心有限公司 用于胎儿血红蛋白再诱导的靶向bcl11a远端调控元件
AU2017252023B2 (en) * 2016-04-18 2024-05-02 Vertex Pharmaceuticals Incorporated Materials and methods for treatment of hemoglobinopathies
DK3636753T5 (da) 2017-06-08 2024-08-26 Univ Osaka Fremgangsmåde til fremstilling af DNA-redigeret eukaryotisk celle
AU2018378479B2 (en) 2017-12-05 2025-03-13 Vertex Pharmaceuticals Incorporated CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor cells and uses thereof
WO2020184723A1 (ja) * 2019-03-14 2020-09-17 国立大学法人徳島大学 Crisprタイプi-dシステムを利用した標的配列改変技術
JP2022547105A (ja) * 2019-09-04 2022-11-10 博雅▲輯▼因(北京)生物科技有限公司 オフターゲット評価に基づく遺伝子編集治療の評価方法
KR20230150998A (ko) * 2021-03-01 2023-10-31 씨포유 가부시키가이샤 Cas3 단백질을 제조하는 방법

Also Published As

Publication number Publication date
CN121844044A (zh) 2026-04-10
WO2025094917A1 (ja) 2025-05-08

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Legal Events

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Effective date: 20251107

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