JP2019512511A5 - - Google Patents
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- Publication number
- JP2019512511A5 JP2019512511A5 JP2018549202A JP2018549202A JP2019512511A5 JP 2019512511 A5 JP2019512511 A5 JP 2019512511A5 JP 2018549202 A JP2018549202 A JP 2018549202A JP 2018549202 A JP2018549202 A JP 2018549202A JP 2019512511 A5 JP2019512511 A5 JP 2019512511A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- conjugate
- pharmaceutically acceptable
- group
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C=NCCOCCC(Nc1cccc(*C(*c2ccccc2)=O)c1)=[U] Chemical compound C=NCCOCCC(Nc1cccc(*C(*c2ccccc2)=O)c1)=[U] 0.000 description 2
- AABHLVKBDJOBDL-UHFFFAOYSA-N CC(C)(CCOC(C)(C)CCC(C=C)=O)N Chemical compound CC(C)(CCOC(C)(C)CCC(C=C)=O)N AABHLVKBDJOBDL-UHFFFAOYSA-N 0.000 description 1
- SNHMUERNLJLMHN-UHFFFAOYSA-N Ic1ccccc1 Chemical compound Ic1ccccc1 SNHMUERNLJLMHN-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662309264P | 2016-03-16 | 2016-03-16 | |
| US201662309268P | 2016-03-16 | 2016-03-16 | |
| US62/309,268 | 2016-03-16 | ||
| US62/309,264 | 2016-03-16 | ||
| PCT/US2017/022785 WO2017161170A1 (en) | 2016-03-16 | 2017-03-16 | Carbonic anhydrase ix targeting agents and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019512511A JP2019512511A (ja) | 2019-05-16 |
| JP2019512511A5 true JP2019512511A5 (enExample) | 2020-04-23 |
| JP7027325B2 JP7027325B2 (ja) | 2022-03-01 |
Family
ID=59852046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018549202A Expired - Fee Related JP7027325B2 (ja) | 2016-03-16 | 2017-03-16 | 炭酸無水酵素ｉｘを標的とする薬剤および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11925696B2 (enExample) |
| EP (1) | EP3429575A4 (enExample) |
| JP (1) | JP7027325B2 (enExample) |
| AU (1) | AU2017234676A1 (enExample) |
| CA (1) | CA3017214A1 (enExample) |
| WO (1) | WO2017161170A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017161170A1 (en) | 2016-03-16 | 2017-09-21 | Purdue Research Foundation | Carbonic anhydrase ix targeting agents and methods |
| EP3429637A4 (en) * | 2016-03-16 | 2020-03-11 | Endocyte, Inc. | CONJUGATES OF CARBONIC ANHYDRASE IX INHIBITORS AND USES THEREOF |
| US20210322582A1 (en) * | 2018-08-30 | 2021-10-21 | Nihon Medi-Physics Co., Ltd. | Radioactive imidazothiadiazole derivative compound |
| AU2024266164A1 (en) * | 2023-05-02 | 2025-10-30 | Rayzebio, Inc. | Radiopharmaceutical compositions targeting carbonic anhydrase ix and uses thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2260875T3 (da) * | 2002-05-06 | 2014-06-30 | Endocyte Inc | Folatreceptor-targetede billeddannelsesmidler |
| AU2004211584B2 (en) * | 2003-01-31 | 2009-11-12 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US20060211074A1 (en) * | 2005-01-12 | 2006-09-21 | Boyce James P | Kinase-directed, activity-based probes |
| CN103893778A (zh) | 2005-08-19 | 2014-07-02 | 恩多塞特公司 | 多药物配体缀合物 |
| US20090043099A1 (en) | 2006-03-17 | 2009-02-12 | The Burnham Institute | Methods and compositions for derepression of IAP-inhibited caspase |
| WO2008101231A2 (en) | 2007-02-16 | 2008-08-21 | Endocyte, Inc. | Methods and compositions for treating and diagnosing kidney disease |
| WO2009002993A1 (en) | 2007-06-25 | 2008-12-31 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| PT2187965T (pt) * | 2007-08-17 | 2020-01-17 | Purdue Research Foundation | Conjugados ligando-ligante de ligação a psma e métodos para utilização |
| EP2240171B1 (en) * | 2008-01-09 | 2014-08-13 | Molecular Insight Pharmaceuticals, Inc. | Inhibitors of carbonic anhydrase IX |
| EP2391714B2 (en) | 2009-01-30 | 2019-07-24 | Whitehead Institute for Biomedical Research | Methods for ligation and uses thereof |
| CN101596433B (zh) | 2009-07-15 | 2011-07-06 | 中国科学院工程热物理研究所 | U形返料器的冷却式隔板 |
| FR2951449B1 (fr) | 2009-10-15 | 2011-11-25 | Commissariat Energie Atomique | Procede de fonctionnalisation de molecules biologiques |
| WO2011090710A2 (en) * | 2009-12-28 | 2011-07-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Composite probes and use thereof in super resolution methods |
| WO2011098610A1 (en) * | 2010-02-12 | 2011-08-18 | Universita Degli Studi Di Firenze | Carbonic anhydrase inhibitors |
| JP5544239B2 (ja) * | 2010-07-29 | 2014-07-09 | 富士フイルム株式会社 | 重合性組成物 |
| EP2707102B1 (en) * | 2011-05-09 | 2019-11-13 | Visen Medical, Inc. | Carbonic anhydrase targeting agents and methods of using same |
| HUE068833T2 (hu) | 2011-08-17 | 2025-01-28 | Merck & Cie Kmg | Albumint megkötõ egységek folát konjugátjai |
| US20140249315A1 (en) | 2013-03-01 | 2014-09-04 | Endocyte, Inc. | Processes for preparing tubulysins |
| US10183970B2 (en) | 2014-01-28 | 2019-01-22 | Tube Pharmaceuticals Gmbh | Cytotoxic tubulysin compounds for conjugation |
| US9771380B2 (en) | 2014-06-09 | 2017-09-26 | University Of Oregon | Gold nanoparticles and methods of making and using gold nanoparticles |
| EP3429637A4 (en) * | 2016-03-16 | 2020-03-11 | Endocyte, Inc. | CONJUGATES OF CARBONIC ANHYDRASE IX INHIBITORS AND USES THEREOF |
| WO2017161170A1 (en) | 2016-03-16 | 2017-09-21 | Purdue Research Foundation | Carbonic anhydrase ix targeting agents and methods |
| CA3019835A1 (en) * | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
-
2017
- 2017-03-16 WO PCT/US2017/022785 patent/WO2017161170A1/en not_active Ceased
- 2017-03-16 US US16/085,393 patent/US11925696B2/en active Active
- 2017-03-16 CA CA3017214A patent/CA3017214A1/en active Pending
- 2017-03-16 EP EP17767563.4A patent/EP3429575A4/en not_active Withdrawn
- 2017-03-16 JP JP2018549202A patent/JP7027325B2/ja not_active Expired - Fee Related
- 2017-03-16 AU AU2017234676A patent/AU2017234676A1/en not_active Abandoned
-
2024
- 2024-02-08 US US18/436,484 patent/US20240316224A1/en not_active Abandoned