JP2019511527A5 - - Google Patents
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- Publication number
- JP2019511527A5 JP2019511527A5 JP2018553364A JP2018553364A JP2019511527A5 JP 2019511527 A5 JP2019511527 A5 JP 2019511527A5 JP 2018553364 A JP2018553364 A JP 2018553364A JP 2018553364 A JP2018553364 A JP 2018553364A JP 2019511527 A5 JP2019511527 A5 JP 2019511527A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- disorder
- alkyl
- muscle
- syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCCc1cc(*)ccc1-c1ncc(*)[n]1Cc1cc(*)ccc1OCCC[C@](CC(O)=O)N Chemical compound CCCc1cc(*)ccc1-c1ncc(*)[n]1Cc1cc(*)ccc1OCCC[C@](CC(O)=O)N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322017P | 2016-04-13 | 2016-04-13 | |
| US62/322,017 | 2016-04-13 | ||
| PCT/US2017/027327 WO2017180818A1 (en) | 2016-04-13 | 2017-04-13 | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019511527A JP2019511527A (ja) | 2019-04-25 |
| JP2019511527A5 true JP2019511527A5 (https=) | 2020-06-18 |
| JP6925367B2 JP6925367B2 (ja) | 2021-08-25 |
Family
ID=58606595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018553364A Active JP6925367B2 (ja) | 2016-04-13 | 2017-04-13 | Ｐｐａｒアゴニスト、化合物、医薬組成物、及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11358954B2 (https=) |
| EP (1) | EP3442948B1 (https=) |
| JP (1) | JP6925367B2 (https=) |
| KR (1) | KR102430906B1 (https=) |
| CN (1) | CN109071459B (https=) |
| BR (1) | BR112018069930B1 (https=) |
| ES (1) | ES2861503T3 (https=) |
| MX (1) | MX380531B (https=) |
| RU (1) | RU2746602C2 (https=) |
| WO (1) | WO2017180818A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA037371B1 (ru) | 2015-10-07 | 2021-03-19 | Митобридж, Инк. | Агонисты ppar, соединения, фармацевтические композиции и способы их применения |
| US11358954B2 (en) | 2016-04-13 | 2022-06-14 | Mitobridge, Inc. | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof |
| ES2887008T3 (es) | 2016-10-05 | 2021-12-21 | Mitobridge Inc | Formas cristalinas y de sal de compuestos agonistas del PPAR |
| US11634387B2 (en) | 2019-09-26 | 2023-04-25 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| CN113912547B (zh) | 2020-07-10 | 2024-04-30 | 成都凡诺西生物医药科技有限公司 | 取代苯丙咪唑类衍生物及其应用 |
| CN112479921B (zh) * | 2020-12-04 | 2022-12-06 | 中国药科大学 | 具有PPARδ激动活性的化合物、药物组合物及医药用途 |
| EP4015623A1 (en) | 2020-12-17 | 2022-06-22 | Universite De Montpellier | Pre-treatment of msc with ppar beta/delta agonist for treatment of ischemia-reperfusion injury |
| WO2022189856A1 (en) | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228281A (en) | 1977-09-23 | 1980-10-14 | Ciba-Geigy Corporation | Dicarboxylic acids containing triazine rings |
| DE4123341A1 (de) | 1991-07-15 | 1993-01-21 | Thomae Gmbh Dr K | Phenylalkylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| GB9511694D0 (en) | 1995-06-09 | 1995-08-02 | Fujisawa Pharmaceutical Co | Benzamide derivatives |
| NZ514453A (en) | 1999-02-26 | 2003-04-29 | Merck & Co Inc | Novel sulfonamide compounds and uses thereof |
| GB9919413D0 (en) | 1999-08-18 | 1999-10-20 | Zeneca Ltd | Chemical compounds |
| ATE447557T1 (de) | 2000-08-17 | 2009-11-15 | Pfizer Ltd | Substitutuierte imidazole als tafia inhibitoren |
| CN100457730C (zh) | 2002-08-29 | 2009-02-04 | 默克公司 | 具有抗糖尿病活性的吲哚化合物 |
| US7820682B2 (en) | 2002-10-03 | 2010-10-26 | Ono Pharmaceutical Co., Ltd. | LPA receptor antagonist |
| WO2004060367A1 (en) | 2002-12-30 | 2004-07-22 | Fujisawa Pharmaceutical Co., Ltd. | Imidazole and triazole derivatives useful as selective cox-1 inhibitors |
| MXPA06003357A (es) | 2003-09-26 | 2006-06-08 | Japan Tobacco Inc | Metodo para inhibir la produccion de lipoproteina remanente. |
| BRPI0515140A (pt) | 2004-09-06 | 2008-07-08 | Hoffmann La Roche | derivados de benzamidina de 4-aminometila e seu emprego como inibidores do fator viia |
| CA2597148A1 (en) | 2005-02-15 | 2007-03-15 | F. Hoffmann-La Roche Ag | Amide derivatives as ppar activators |
| BRPI0615948A2 (pt) | 2005-09-07 | 2011-05-31 | Plexxikon Inc | composto ativo de ppar, sua composição, seu kit e seu uso |
| NZ569329A (en) | 2006-01-30 | 2011-09-30 | Transtech Pharma Inc | Substituted imidazole derivatives and their use as PTPase inhibitors |
| MX2008012404A (es) | 2006-03-28 | 2008-10-09 | Novartis Ag | Derivados de amida y su aplicacion para el tratamiento de enfermedades relacionadas con proteina-g. |
| CN101466687B (zh) | 2006-04-18 | 2012-04-11 | 日本化学医药株式会社 | 过氧化物酶体增殖剂激活受体δ的激活剂 |
| DE102006023336A1 (de) | 2006-05-18 | 2007-11-22 | Merck Patent Gmbh | 1,5-Diphenyl-pyrazole II |
| CN101085772A (zh) | 2006-06-07 | 2007-12-12 | 上海艾力斯医药科技有限公司 | 一类具有PPARγ激动剂活性的化合物及其应用 |
| EP2128138A1 (en) | 2007-01-29 | 2009-12-02 | Takeda Pharmaceutical Company Limited | Pyrazole compound |
| KR20080082541A (ko) | 2007-03-07 | 2008-09-11 | 동아제약주식회사 | 퍼옥시좀 증식자-활성화 감마 수용체를 조절하는 신규한페닐프로판산 유도체의 제조방법 및 약학적 용도 |
| JP2008285452A (ja) | 2007-05-21 | 2008-11-27 | Ono Pharmaceut Co Ltd | ＰＰＡＲα／γデュアルアゴニストおよび糖尿病治療薬を組み合わせてなる医薬 |
| CA2710764A1 (en) | 2007-12-28 | 2009-07-09 | The Salk Institute For Biological Studies | Methods for enhancing muscle performance and tone |
| EP2981522A4 (en) | 2013-04-05 | 2016-08-31 | Salk Inst For Biological Studi | PPAR AGONISTS |
| WO2015035171A1 (en) | 2013-09-09 | 2015-03-12 | High Point Pharmaceuticals, Llc | Use of a ppar-delta agonist for treating muscle atrophy |
| US20170305894A1 (en) | 2014-10-08 | 2017-10-26 | Mitobridge, Inc. | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
| WO2016057322A1 (en) | 2014-10-08 | 2016-04-14 | Salk Institute For Biological Studies | Ppar agonists and methods of use thereof |
| EA037371B1 (ru) | 2015-10-07 | 2021-03-19 | Митобридж, Инк. | Агонисты ppar, соединения, фармацевтические композиции и способы их применения |
| US11358954B2 (en) | 2016-04-13 | 2022-06-14 | Mitobridge, Inc. | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof |
| ES2859487T3 (es) * | 2016-10-05 | 2021-10-04 | Mitobridge Inc | Métodos para tratar las lesiones renales agudas |
-
2017
- 2017-04-13 US US16/092,232 patent/US11358954B2/en active Active
- 2017-04-13 EP EP17718784.6A patent/EP3442948B1/en active Active
- 2017-04-13 WO PCT/US2017/027327 patent/WO2017180818A1/en not_active Ceased
- 2017-04-13 ES ES17718784T patent/ES2861503T3/es active Active
- 2017-04-13 RU RU2018137521A patent/RU2746602C2/ru active
- 2017-04-13 CN CN201780023617.7A patent/CN109071459B/zh active Active
- 2017-04-13 JP JP2018553364A patent/JP6925367B2/ja active Active
- 2017-04-13 KR KR1020187031232A patent/KR102430906B1/ko active Active
- 2017-04-13 MX MX2018012538A patent/MX380531B/es unknown
- 2017-04-13 BR BR112018069930-6A patent/BR112018069930B1/pt active IP Right Grant
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