KR102430906B1 - Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 - Google Patents

Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 Download PDF

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KR102430906B1
KR102430906B1 KR1020187031232A KR20187031232A KR102430906B1 KR 102430906 B1 KR102430906 B1 KR 102430906B1 KR 1020187031232 A KR1020187031232 A KR 1020187031232A KR 20187031232 A KR20187031232 A KR 20187031232A KR 102430906 B1 KR102430906 B1 KR 102430906B1
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disease
compound
mmol
pharmaceutically acceptable
methyl
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KR20180133435A (ko
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바라트 라구
라메쉬 세나이아르
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미토브리지, 인크.
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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KR1020187031232A 2016-04-13 2017-04-13 Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 Active KR102430906B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662322017P 2016-04-13 2016-04-13
US62/322,017 2016-04-13
PCT/US2017/027327 WO2017180818A1 (en) 2016-04-13 2017-04-13 Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof

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KR20180133435A KR20180133435A (ko) 2018-12-14
KR102430906B1 true KR102430906B1 (ko) 2022-08-10

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US (1) US11358954B2 (https=)
EP (1) EP3442948B1 (https=)
JP (1) JP6925367B2 (https=)
KR (1) KR102430906B1 (https=)
CN (1) CN109071459B (https=)
BR (1) BR112018069930B1 (https=)
ES (1) ES2861503T3 (https=)
MX (1) MX380531B (https=)
RU (1) RU2746602C2 (https=)
WO (1) WO2017180818A1 (https=)

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EA037371B1 (ru) 2015-10-07 2021-03-19 Митобридж, Инк. Агонисты ppar, соединения, фармацевтические композиции и способы их применения
US11358954B2 (en) 2016-04-13 2022-06-14 Mitobridge, Inc. PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
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US11634387B2 (en) 2019-09-26 2023-04-25 Abionyx Pharma Sa Compounds useful for treating liver diseases
CN113912547B (zh) 2020-07-10 2024-04-30 成都凡诺西生物医药科技有限公司 取代苯丙咪唑类衍生物及其应用
CN112479921B (zh) * 2020-12-04 2022-12-06 中国药科大学 具有PPARδ激动活性的化合物、药物组合物及医药用途
EP4015623A1 (en) 2020-12-17 2022-06-22 Universite De Montpellier Pre-treatment of msc with ppar beta/delta agonist for treatment of ischemia-reperfusion injury
WO2022189856A1 (en) 2021-03-08 2022-09-15 Abionyx Pharma Sa Compounds useful for treating liver diseases
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease

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EP3442948B1 (en) 2020-12-16
ES2861503T3 (es) 2021-10-06
CN109071459B (zh) 2022-08-16
KR20180133435A (ko) 2018-12-14
EP3442948A1 (en) 2019-02-20
RU2746602C2 (ru) 2021-04-16
US11358954B2 (en) 2022-06-14
BR112018069930A2 (pt) 2019-02-05
CN109071459A (zh) 2018-12-21
JP6925367B2 (ja) 2021-08-25
RU2018137521A3 (https=) 2020-10-28
JP2019511527A (ja) 2019-04-25
BR112018069930B1 (pt) 2024-02-20
MX2018012538A (es) 2019-02-25
MX380531B (es) 2025-03-12
US20200347037A1 (en) 2020-11-05
WO2017180818A1 (en) 2017-10-19
CA3019014A1 (en) 2017-10-19
RU2018137521A (ru) 2020-05-13

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