JP2019508455A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019508455A5 JP2019508455A5 JP2018548356A JP2018548356A JP2019508455A5 JP 2019508455 A5 JP2019508455 A5 JP 2019508455A5 JP 2018548356 A JP2018548356 A JP 2018548356A JP 2018548356 A JP2018548356 A JP 2018548356A JP 2019508455 A5 JP2019508455 A5 JP 2019508455A5
- Authority
- JP
- Japan
- Prior art keywords
- fistula
- agent according
- weeks
- patient
- remission
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010016717 Fistula Diseases 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 230000003890 fistula Effects 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 4
- 238000002560 therapeutic procedure Methods 0.000 claims 4
- 208000011231 Crohn disease Diseases 0.000 claims 3
- 210000000577 adipose tissue Anatomy 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- -1 and HLAII Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 229960003444 immunosuppressant agent Drugs 0.000 claims 2
- 230000001861 immunosuppressant effect Effects 0.000 claims 2
- 239000003018 immunosuppressive agent Substances 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 102100022464 5'-nucleotidase Human genes 0.000 claims 1
- 102100032912 CD44 antigen Human genes 0.000 claims 1
- 102100022002 CD59 glycoprotein Human genes 0.000 claims 1
- 102100037241 Endoglin Human genes 0.000 claims 1
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 claims 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 1
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 1
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 1
- 101000897400 Homo sapiens CD59 glycoprotein Proteins 0.000 claims 1
- 101000881679 Homo sapiens Endoglin Proteins 0.000 claims 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 1
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims 1
- 101000935043 Homo sapiens Integrin beta-1 Proteins 0.000 claims 1
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 1
- 101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 claims 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims 1
- 102100022338 Integrin alpha-M Human genes 0.000 claims 1
- 102100022297 Integrin alpha-X Human genes 0.000 claims 1
- 102100025304 Integrin beta-1 Human genes 0.000 claims 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims 1
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 1
- 102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 claims 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021083406A JP2021119789A (ja) | 2016-03-14 | 2021-05-17 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1604304.4 | 2016-03-14 | ||
| GBGB1604304.4A GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| PCT/IB2017/051468 WO2017158509A1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083406A Division JP2021119789A (ja) | 2016-03-14 | 2021-05-17 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019508455A JP2019508455A (ja) | 2019-03-28 |
| JP2019508455A5 true JP2019508455A5 (OSRAM) | 2020-04-23 |
| JP6931656B2 JP6931656B2 (ja) | 2021-09-08 |
Family
ID=55952284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018548356A Active JP6931656B2 (ja) | 2016-03-14 | 2017-03-14 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
| JP2021083406A Pending JP2021119789A (ja) | 2016-03-14 | 2021-05-17 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083406A Pending JP2021119789A (ja) | 2016-03-14 | 2021-05-17 | クローン病における肛囲複雑瘻孔の治療において使用するための脂肪組織由来間質幹細胞 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US10357518B2 (OSRAM) |
| EP (2) | EP3219321B1 (OSRAM) |
| JP (2) | JP6931656B2 (OSRAM) |
| KR (1) | KR102277789B1 (OSRAM) |
| CN (2) | CN108883135B (OSRAM) |
| AU (1) | AU2017232718B2 (OSRAM) |
| BE (1) | BE1024781B1 (OSRAM) |
| CA (1) | CA3017694C (OSRAM) |
| CY (1) | CY1125513T1 (OSRAM) |
| DE (1) | DE102017002458B4 (OSRAM) |
| DK (1) | DK3219321T3 (OSRAM) |
| ES (2) | ES2911718T3 (OSRAM) |
| FR (1) | FR3048614B1 (OSRAM) |
| GB (2) | GB201604304D0 (OSRAM) |
| HR (1) | HRP20220539T1 (OSRAM) |
| HU (1) | HUE058739T2 (OSRAM) |
| IL (2) | IL298107B2 (OSRAM) |
| LT (1) | LT3219321T (OSRAM) |
| MX (1) | MX2018010699A (OSRAM) |
| NL (1) | NL2018512B1 (OSRAM) |
| NO (1) | NO345415B1 (OSRAM) |
| PL (1) | PL3219321T3 (OSRAM) |
| RS (1) | RS63163B1 (OSRAM) |
| RU (1) | RU2742308C2 (OSRAM) |
| SG (2) | SG10202008992YA (OSRAM) |
| SI (1) | SI3219321T1 (OSRAM) |
| WO (1) | WO2017158509A1 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US20210401895A1 (en) | 2017-03-30 | 2021-12-30 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
| AU2020228979B2 (en) * | 2019-02-27 | 2025-05-29 | Takeda Pharmaceutical Company Limited | Improved stem cell populations for allogeneic therapy |
| JP2023517641A (ja) * | 2020-03-11 | 2023-04-26 | メゾブラスト・インターナショナル・エスアーエールエル | 炎症性腸疾患を治療するための方法ｉｉ |
| CN115361957A (zh) * | 2020-03-11 | 2022-11-18 | 迈索布拉斯特国际有限公司 | 治疗炎症性肠病的方法i |
| CN111481573A (zh) * | 2020-03-26 | 2020-08-04 | 卡替（上海）生物技术股份有限公司 | 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途 |
| WO2022115609A1 (en) * | 2020-11-25 | 2022-06-02 | Flagship Pioneering, Inc. | Adipogenic cell compositions and methods |
| EP4531879A1 (en) * | 2022-05-25 | 2025-04-09 | Flagship Pioneering Innovations VI, LLC | Compositions of secretory and/or catalytic cells and methods using the same |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US6010696A (en) | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
| US5733542A (en) | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| FR2680931B1 (fr) | 1991-08-27 | 1997-08-14 | Thomson Csf | Procede de detection et de suivi d'objets en mouvement par analyse de sequences d'images. |
| BR9307550A (pt) | 1992-12-02 | 1999-05-25 | Shell Int Research | Composto fungicida processo para a preparação de um composto fungicida composição fungicida processo de combate aos fungos em um local e uso |
| US5578475A (en) | 1993-07-12 | 1996-11-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| US5472183A (en) | 1994-03-17 | 1995-12-05 | Nisca Corporation | Sheet feeding device with multiple sheet stackers |
| US6174333B1 (en) | 1994-06-06 | 2001-01-16 | Osiris Therapeutics, Inc. | Biomatrix for soft tissue regeneration using mesenchymal stem cells |
| JPH10505250A (ja) | 1994-06-06 | 1998-05-26 | ケース ウエスターン リザーブ ユニバーシティ | 組織再生のためのバイオマトリックス |
| ATE285477T1 (de) | 1995-06-07 | 2005-01-15 | Inex Pharmaceutical Corp | Herstellung von lipid-nukleinsäure partikeln duch ein hydrophobische lipid-nukleinsäuree komplexe zwischenprodukt und zur verwendung in der gentransfer |
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| US6546106B2 (en) | 1996-09-03 | 2003-04-08 | New Transducers Limited | Acoustic device |
| US5705308A (en) | 1996-09-30 | 1998-01-06 | Eastman Kodak Company | Infrared-sensitive, negative-working diazonaphthoquinone imaging composition and element |
| DE69841850D1 (de) | 1997-12-02 | 2010-09-30 | Artecel Sciences Inc | Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen |
| US6368636B1 (en) | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| US9585916B2 (en) | 1999-03-26 | 2017-03-07 | Northern Therapeutics Inc. | Cell based therapy for the pulmonary system |
| DE69910362T2 (de) | 1998-04-03 | 2004-06-24 | Osiris Therapeutics, Inc. | Anwendung der mesenchymalen stammzellen als immunsuppressiva |
| US6546105B1 (en) | 1998-10-30 | 2003-04-08 | Matsushita Electric Industrial Co., Ltd. | Sound image localization device and sound image localization method |
| EP1165830B1 (en) | 1999-03-10 | 2017-07-12 | University of Pittsburgh of the Commonwealth System of Higher Education | Adipose-derived stem cells and lattices |
| US20030082152A1 (en) | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
| US20050153442A1 (en) | 1999-03-10 | 2005-07-14 | Adam Katz | Adipose-derived stem cells and lattices |
| US6777231B1 (en) | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
| CN1201268C (zh) | 1999-06-30 | 2005-05-11 | 国际商业机器公司 | 实现运动模糊化的图像处理 |
| US7670628B2 (en) | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
| US6555374B1 (en) | 1999-08-19 | 2003-04-29 | Artecel Sciences, Inc. | Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof |
| CA2438904C (en) | 2001-02-23 | 2012-09-04 | The University Of Pittsburgh | Rapid preparation of stem cell matrices for use in tissue and organ treatment and repair |
| US20030054331A1 (en) | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| AU2002356935A1 (en) | 2001-11-09 | 2003-05-19 | Artecel Sciences, Inc. | Methods and compositions for the use of stromal cells to support embryonic and adult stem cells |
| EP1453954A4 (en) * | 2001-11-09 | 2004-12-15 | Artecel Sciences Inc | Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof |
| US7771716B2 (en) | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
| EP1499347A2 (en) | 2002-03-15 | 2005-01-26 | Department of Veterans Affairs, Rehabilitation R&D Service | Methods and compositions using cellular asialodeterminants and glycoconjugates for targeting cells to tissues and organs |
| DK1513877T3 (da) | 2002-06-14 | 2008-06-02 | Cartela Ab | Markör for stamceller og dens anvendelse |
| US20040101959A1 (en) | 2002-11-21 | 2004-05-27 | Olga Marko | Treatment of tissue with undifferentiated mesenchymal cells |
| CA2809195C (en) | 2003-04-01 | 2014-05-20 | United States Of America Department Of Veteran's Affairs | Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction |
| ES2265199B1 (es) | 2003-06-12 | 2008-02-01 | Cellerix, S.L. | Celulas madre adultas multipotentes procedentes de condrocitos desdiferenciados y sus aplicaciones. |
| AU2004252568B2 (en) | 2003-06-27 | 2011-06-30 | Ethicon, Incorporated | Regeneration and repair of neural tissue using postpartum-derived cells |
| US7645229B2 (en) | 2003-09-26 | 2010-01-12 | Armstrong David N | Instrument and method for endoscopic visualization and treatment of anorectal fistula |
| KR20060036933A (ko) | 2003-10-07 | 2006-05-02 | 바이오마스터 인코포레이티드 | 지방-유래 전구세포의 세포 분화 |
| JP4217262B2 (ja) | 2003-11-04 | 2009-01-28 | 株式会社バイオマスター | 脂肪組織から幹細胞を調製するための方法およびシステム |
| US20080095749A1 (en) | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| EP2298863B1 (en) | 2004-03-22 | 2015-07-22 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
| RU2252252C1 (ru) | 2004-04-09 | 2005-05-20 | Тепляшин Александр Сергеевич | Способ выделения мезенхимальных стволовых клеток |
| ES2313805B1 (es) | 2004-10-04 | 2009-12-23 | Cellerix, S.L. | Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral. |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| ES2264862B8 (es) | 2004-08-25 | 2017-01-20 | Cellerix, S.L. | Biomaterial para sutura. |
| WO2006029347A2 (en) | 2004-09-03 | 2006-03-16 | University Of Maryland, Baltimore | Integrin cd18 is a novel stromal stem cell marker and functions to promote osteogenesis |
| US20060286089A1 (en) | 2005-04-08 | 2006-12-21 | Xcyte Therapies, Inc. | Compositions and methods for the treatment of burns and sepsis |
| DK1926813T4 (da) | 2005-09-23 | 2019-08-19 | Tigenix S A U | Cellepopulationer med immunregulatorisk aktivitet, fremgangsmåde til isolering og anvendelser |
| EP1795588A1 (en) | 2005-12-07 | 2007-06-13 | Cellerix, S.L. | Use of adipose tissue derived mesenchymal stem cells for the treatment of graft versus host disease |
| WO2008036374A2 (en) | 2006-09-21 | 2008-03-27 | Medistem Laboratories, Inc. | Allogeneic stem cell transplants in non-conditioned recipients |
| WO2009031606A1 (ja) | 2007-09-07 | 2009-03-12 | Jcr Pharmaceuticals Co., Ltd. | 関節炎治療及び予防剤 |
| EP3103463B1 (en) | 2007-09-19 | 2020-01-01 | Pluristem Ltd. | Adherent cells from adipose or placenta tissues and use thereof in therapy |
| KR20100076031A (ko) | 2007-10-17 | 2010-07-05 | 티엑셀 | Ｔｒ１ 세포, 중간엽 줄기 세포 및 이들의 용도 |
| GB0814249D0 (en) | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| ES2345867B1 (es) * | 2009-04-03 | 2011-07-28 | Fundacion Instituto Mediterraneo Para La Biotecnologia Y La Investigacion Sanitaria (Imabis) | Celulas madre multipotentes derivadas de estroma de mesenterio. |
| DK2425844T3 (da) * | 2009-04-28 | 2014-06-16 | Anterogen Co Ltd | Autolog og allogen stromastamcellesammensætning, der stammer fra fedtvæv, til behandling af fistler |
| CN107007626A (zh) | 2009-07-09 | 2017-08-04 | 蒂盖尼克斯公司 | 用于细胞治疗的方法和组合物 |
| AU2011338682B2 (en) * | 2010-12-06 | 2017-04-27 | Quark Pharmaceuticals, Inc. | Double stranded oligonucleotide compounds comprising threose modifications |
| KR101900664B1 (ko) | 2011-01-12 | 2018-09-21 | 타이제닉스, 에스.에이.유. | 자가면역 및 염증성 질환에서 림프내 투여를 위한 지방-유래 중간엽 줄기 세포 |
| EP2683813A1 (en) | 2011-03-11 | 2014-01-15 | TiGenix, S.A.U. | Cell populations having immunoregulatory activity, method for isolation and uses |
| US20140134140A1 (en) | 2012-11-09 | 2014-05-15 | Case Western Reserve University | Mesenchymal stem cell compositions for the treatment of microbial infections |
| JP6567430B2 (ja) * | 2013-03-15 | 2019-08-28 | ティゲニクス、エセ、ア、ウＴｉＧｅｎｉｘ，Ｓ．Ａ．Ｕ． | 細胞治療に対する臨床反応を決定するためのリンパ球バイオマーカー |
| US20160120910A1 (en) | 2013-06-25 | 2016-05-05 | Tigenix S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| WO2016001846A1 (en) * | 2014-06-30 | 2016-01-07 | Tigenix S.A.U. | Mesenchymal stromal cells for treating sepsis |
| WO2017051421A1 (en) * | 2015-09-24 | 2017-03-30 | Cellect Biotherapeutics Ltd. | Methods for propagating mesenchymal stem cells (msc) for use in transplantation |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US10152822B2 (en) | 2017-04-01 | 2018-12-11 | Intel Corporation | Motion biased foveated renderer |
| US10890966B2 (en) | 2017-07-27 | 2021-01-12 | Arm Limited | Graphics processing systems |
| US10818080B2 (en) | 2018-07-25 | 2020-10-27 | Disney Enterprises, Inc. | Piecewise-polynomial coupling layers for warp-predicting neural networks |
| US11109065B2 (en) | 2018-09-26 | 2021-08-31 | Google Llc | Video encoding by providing geometric proxies |
-
2016
- 2016-03-14 GB GBGB1604304.4A patent/GB201604304D0/en not_active Ceased
-
2017
- 2017-03-14 LT LTEP17160932.4T patent/LT3219321T/lt unknown
- 2017-03-14 BE BE2017/5156A patent/BE1024781B1/de active IP Right Grant
- 2017-03-14 EP EP17160932.4A patent/EP3219321B1/en active Active
- 2017-03-14 NL NL2018512A patent/NL2018512B1/nl active
- 2017-03-14 EP EP22163484.3A patent/EP4074322A1/en not_active Withdrawn
- 2017-03-14 DE DE102017002458.8A patent/DE102017002458B4/de active Active
- 2017-03-14 WO PCT/IB2017/051468 patent/WO2017158509A1/en not_active Ceased
- 2017-03-14 KR KR1020187029414A patent/KR102277789B1/ko active Active
- 2017-03-14 NO NO20170376A patent/NO345415B1/en unknown
- 2017-03-14 SG SG10202008992YA patent/SG10202008992YA/en unknown
- 2017-03-14 IL IL298107A patent/IL298107B2/en unknown
- 2017-03-14 DK DK17160932.4T patent/DK3219321T3/da active
- 2017-03-14 IL IL261730A patent/IL261730B2/en unknown
- 2017-03-14 GB GB1704065.0A patent/GB2548490B/en active Active
- 2017-03-14 AU AU2017232718A patent/AU2017232718B2/en active Active
- 2017-03-14 RS RS20220355A patent/RS63163B1/sr unknown
- 2017-03-14 FR FR1752073A patent/FR3048614B1/fr active Active
- 2017-03-14 ES ES17160932T patent/ES2911718T3/es active Active
- 2017-03-14 CN CN201780017154.3A patent/CN108883135B/zh active Active
- 2017-03-14 CA CA3017694A patent/CA3017694C/en active Active
- 2017-03-14 PL PL17160932T patent/PL3219321T3/pl unknown
- 2017-03-14 JP JP2018548356A patent/JP6931656B2/ja active Active
- 2017-03-14 HU HUE17160932A patent/HUE058739T2/hu unknown
- 2017-03-14 SG SG11201807404XA patent/SG11201807404XA/en unknown
- 2017-03-14 HR HRP20220539TT patent/HRP20220539T1/hr unknown
- 2017-03-14 US US15/458,509 patent/US10357518B2/en active Active
- 2017-03-14 SI SI201731122T patent/SI3219321T1/sl unknown
- 2017-03-14 MX MX2018010699A patent/MX2018010699A/es unknown
- 2017-03-14 ES ES201700204A patent/ES2681774B1/es active Active
- 2017-03-14 RU RU2018131519A patent/RU2742308C2/ru active
- 2017-03-14 CN CN202211257331.4A patent/CN115569151A/zh active Pending
-
2019
- 2019-06-25 US US16/452,321 patent/US11273182B2/en active Active
-
2021
- 2021-05-17 JP JP2021083406A patent/JP2021119789A/ja active Pending
-
2022
- 2022-02-14 US US17/671,479 patent/US12213998B2/en active Active
- 2022-04-20 CY CY20221100296T patent/CY1125513T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019508455A5 (OSRAM) | ||
| JP2021119789A5 (OSRAM) | ||
| Maumus et al. | Mesenchymal stem cells in regenerative medicine applied to rheumatic diseases: role of secretome and exosomes | |
| US20220088084A1 (en) | Uses of mesenchymal stem cells | |
| Wu et al. | Therapeutic potential of human umbilical cord derived stem cells in a rat myocardial infarction model | |
| US8562973B2 (en) | Treatment of sarcoidosis using placental stem cells | |
| Mei et al. | Advances and clinical challenges of mesenchymal stem cell therapy | |
| RU2018131519A (ru) | Стромальные стволовые клетки жировой ткани для использования в лечении рефракторных сложных перианальных фистул при болезни крона | |
| He et al. | Injection of Sca-1+/CD45+/CD31+ mouse bone mesenchymal stromal-like cells improves cardiac function in a mouse myocardial infarct model | |
| Alamoudi et al. | Treatment of oral ulcers in dogs using adipose tissue-derived mesenchymal stem cells | |
| JP2015521630A5 (OSRAM) | ||
| Wobma et al. | Mesenchymal stromal cells: Getting ready for clinical primetime | |
| CN111212654A (zh) | 用激活的调节性t细胞治疗肝衰竭 | |
| JP2017520582A5 (OSRAM) | ||
| Chen et al. | Current state of heart failure treatment: are mesenchymal stem cells and their exosomes a future therapy? | |
| ES2742035T3 (es) | Tratamiento de las enfermedades de la disfunción y la inflamación endotelial | |
| KR101774751B1 (ko) | Il-17 산생 억제 조성물 | |
| CN106581763A (zh) | 一种干细胞人微型器官的制备方法 | |
| Hsu et al. | Challenges and Perspectives on the Use of Pericytes in Tissue Engineering | |
| Ishii | Stem Cell Therapy and Regenerative | |
| Carvalho et al. | UM171 EXPANDS IMMATURE BONE MARROW CD34+ CELLS FROM PATIENTS WITH TELOMEROPATHIES | |
| Li et al. | 253. The Use of Osteoporotic BMSCs Engineered by Baculovirus-Mediated MicroRNAs Sponge to Heal Osteoporotic Bone Defect | |
| AU2015268704B2 (en) | Uses of mesenchymal stem cells | |
| Dong et al. | Recombinant adeno-associated virus type 9 transfection of mouse bone marrow mesenchymal stem cells | |
| Vaes¹ et al. | frontiers in REVIEW ARTICLE IMMUNOLOGY published: 27 November 2012 |