SI3219321T1 - Iz adipoznega tkiva izpeljane stromalne matične celice za uporabo pri zdravljenju refraktarnih kompleksnih perianalnih fistul pri Crohnovi bolezni - Google Patents

Iz adipoznega tkiva izpeljane stromalne matične celice za uporabo pri zdravljenju refraktarnih kompleksnih perianalnih fistul pri Crohnovi bolezni

Info

Publication number
SI3219321T1
SI3219321T1 SI201731122T SI201731122T SI3219321T1 SI 3219321 T1 SI3219321 T1 SI 3219321T1 SI 201731122 T SI201731122 T SI 201731122T SI 201731122 T SI201731122 T SI 201731122T SI 3219321 T1 SI3219321 T1 SI 3219321T1
Authority
SI
Slovenia
Prior art keywords
crohn
disease
stem cells
adipose tissue
derived stromal
Prior art date
Application number
SI201731122T
Other languages
English (en)
Slovenian (sl)
Inventor
Eduardo Bravo
Maria Pascual
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of SI3219321T1 publication Critical patent/SI3219321T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201731122T 2016-03-14 2017-03-14 Iz adipoznega tkiva izpeljane stromalne matične celice za uporabo pri zdravljenju refraktarnih kompleksnih perianalnih fistul pri Crohnovi bolezni SI3219321T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1604304.4A GB201604304D0 (en) 2016-03-14 2016-03-14 Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
EP17160932.4A EP3219321B1 (en) 2016-03-14 2017-03-14 Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease

Publications (1)

Publication Number Publication Date
SI3219321T1 true SI3219321T1 (sl) 2022-05-31

Family

ID=55952284

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201731122T SI3219321T1 (sl) 2016-03-14 2017-03-14 Iz adipoznega tkiva izpeljane stromalne matične celice za uporabo pri zdravljenju refraktarnih kompleksnih perianalnih fistul pri Crohnovi bolezni

Country Status (27)

Country Link
US (3) US10357518B2 (OSRAM)
EP (2) EP3219321B1 (OSRAM)
JP (2) JP6931656B2 (OSRAM)
KR (1) KR102277789B1 (OSRAM)
CN (2) CN108883135B (OSRAM)
AU (1) AU2017232718B2 (OSRAM)
BE (1) BE1024781B1 (OSRAM)
CA (1) CA3017694C (OSRAM)
CY (1) CY1125513T1 (OSRAM)
DE (1) DE102017002458B4 (OSRAM)
DK (1) DK3219321T3 (OSRAM)
ES (2) ES2911718T3 (OSRAM)
FR (1) FR3048614B1 (OSRAM)
GB (2) GB201604304D0 (OSRAM)
HR (1) HRP20220539T1 (OSRAM)
HU (1) HUE058739T2 (OSRAM)
IL (2) IL298107B2 (OSRAM)
LT (1) LT3219321T (OSRAM)
MX (1) MX2018010699A (OSRAM)
NL (1) NL2018512B1 (OSRAM)
NO (1) NO345415B1 (OSRAM)
PL (1) PL3219321T3 (OSRAM)
RS (1) RS63163B1 (OSRAM)
RU (1) RU2742308C2 (OSRAM)
SG (2) SG10202008992YA (OSRAM)
SI (1) SI3219321T1 (OSRAM)
WO (1) WO2017158509A1 (OSRAM)

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AU2020228979B2 (en) * 2019-02-27 2025-05-29 Takeda Pharmaceutical Company Limited Improved stem cell populations for allogeneic therapy
JP2023517641A (ja) * 2020-03-11 2023-04-26 メゾブラスト・インターナショナル・エスアーエールエル 炎症性腸疾患を治療するための方法ｉｉ
CN115361957A (zh) * 2020-03-11 2022-11-18 迈索布拉斯特国际有限公司 治疗炎症性肠病的方法i
CN111481573A (zh) * 2020-03-26 2020-08-04 卡替（上海）生物技术股份有限公司 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途
WO2022115609A1 (en) * 2020-11-25 2022-06-02 Flagship Pioneering, Inc. Adipogenic cell compositions and methods
EP4531879A1 (en) * 2022-05-25 2025-04-09 Flagship Pioneering Innovations VI, LLC Compositions of secretory and/or catalytic cells and methods using the same

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Also Published As

Publication number Publication date
AU2017232718B2 (en) 2024-01-18
LT3219321T (lt) 2022-05-10
US20170258851A1 (en) 2017-09-14
BE1024781A1 (de) 2018-06-27
CA3017694A1 (en) 2017-09-21
PL3219321T3 (pl) 2022-05-30
KR20180120261A (ko) 2018-11-05
BE1024781B1 (de) 2018-07-02
FR3048614B1 (fr) 2020-02-21
IL298107B1 (en) 2023-10-01
GB2548490B (en) 2020-09-02
EP4074322A1 (en) 2022-10-19
DE102017002458A1 (de) 2017-09-14
BR112018068493A8 (pt) 2022-06-28
RS63163B1 (sr) 2022-05-31
HRP20220539T1 (hr) 2022-06-10
GB2548490A (en) 2017-09-20
IL298107B2 (en) 2024-02-01
IL261730B1 (en) 2024-01-01
ES2911718T3 (es) 2022-05-20
CA3017694C (en) 2024-02-27
US10357518B2 (en) 2019-07-23
IL261730B2 (en) 2024-05-01
RU2742308C2 (ru) 2021-02-04
NL2018512A (en) 2017-03-30
DE102017002458B4 (de) 2019-04-25
KR102277789B1 (ko) 2021-07-15
GB201704065D0 (en) 2017-04-26
GB201604304D0 (en) 2016-04-27
IL298107A (en) 2023-01-01
CY1125513T1 (el) 2024-12-13
CN115569151A (zh) 2023-01-06
ES2681774A1 (es) 2018-09-14
US20220249574A1 (en) 2022-08-11
HUE058739T2 (hu) 2022-09-28
RU2018131519A3 (OSRAM) 2020-07-10
NL2018512B1 (en) 2017-09-07
JP6931656B2 (ja) 2021-09-08
RU2018131519A (ru) 2020-04-15
SG11201807404XA (en) 2018-09-27
MX2018010699A (es) 2019-01-14
WO2017158509A1 (en) 2017-09-21
NO20170376A1 (en) 2017-09-15
JP2019508455A (ja) 2019-03-28
SG10202008992YA (en) 2020-10-29
BR112018068493A2 (pt) 2019-01-22
IL261730A (en) 2018-10-31
US20190381106A1 (en) 2019-12-19
CN108883135A (zh) 2018-11-23
FR3048614A1 (OSRAM) 2017-09-15
ES2681774B1 (es) 2019-12-26
EP3219321B1 (en) 2022-03-30
DK3219321T3 (da) 2022-04-25
JP2021119789A (ja) 2021-08-19
NO345415B1 (en) 2021-01-18
EP3219321A1 (en) 2017-09-20
CN108883135B (zh) 2022-11-04
AU2017232718A1 (en) 2018-10-04
US11273182B2 (en) 2022-03-15
US12213998B2 (en) 2025-02-04

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