JP2019508433A - Liv1−adc及び化学療法剤を用いた併用療法 - Google Patents

Liv1−adc及び化学療法剤を用いた併用療法 Download PDF

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JP2019508433A
JP2019508433A JP2018546036A JP2018546036A JP2019508433A JP 2019508433 A JP2019508433 A JP 2019508433A JP 2018546036 A JP2018546036 A JP 2018546036A JP 2018546036 A JP2018546036 A JP 2018546036A JP 2019508433 A JP2019508433 A JP 2019508433A
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liv
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administered
adc
cancer
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JP2019508433A5 (OSRAM
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サスマン,ジアンゴ
リー,フー
コスティチ,アナ
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シアトル ジェネティクス,インコーポレーテッド
シアトル ジェネティクス,インコーポレーテッド
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Publication of JP2019508433A5 publication Critical patent/JP2019508433A5/ja
Priority to JP2022006944A priority Critical patent/JP2022058676A/ja
Priority to JP2024039750A priority patent/JP2024075639A/ja
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    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6855Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • C07KPEPTIDES
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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JP2018546036A 2016-03-15 2017-03-15 Liv1−adc及び化学療法剤を用いた併用療法 Pending JP2019508433A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022006944A JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662308639P 2016-03-15 2016-03-15
US62/308,639 2016-03-15
US201662317792P 2016-04-04 2016-04-04
US62/317,792 2016-04-04
US201662367510P 2016-07-27 2016-07-27
US62/367,510 2016-07-27
PCT/US2017/022541 WO2017161007A1 (en) 2016-03-15 2017-03-15 Combination therapy using a liv1-adc and a chemotherapeutic

Related Child Applications (1)

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JP2022006944A Division JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法

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JP2019508433A true JP2019508433A (ja) 2019-03-28
JP2019508433A5 JP2019508433A5 (OSRAM) 2020-04-23

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JP2018546036A Pending JP2019508433A (ja) 2016-03-15 2017-03-15 Liv1−adc及び化学療法剤を用いた併用療法
JP2022006944A Pending JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A Pending JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

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JP2022006944A Pending JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A Pending JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

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US (2) US11325980B2 (OSRAM)
EP (1) EP3429626A4 (OSRAM)
JP (3) JP2019508433A (OSRAM)
KR (3) KR20220157515A (OSRAM)
CN (1) CN108697801A (OSRAM)
AU (2) AU2017235545A1 (OSRAM)
BR (1) BR112018068129A2 (OSRAM)
CA (1) CA3016485A1 (OSRAM)
EA (1) EA201891968A1 (OSRAM)
IL (1) IL261505A (OSRAM)
MA (1) MA45324A (OSRAM)
MX (2) MX2018010847A (OSRAM)
SG (2) SG11201807526SA (OSRAM)
WO (1) WO2017161007A1 (OSRAM)

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Publication number Priority date Publication date Assignee Title
PT2648752T (pt) 2010-12-06 2017-03-28 Seattle Genetics Inc Anticorpos humanizados a liv-1 e seu uso para tratar o cancro
BR112020010937A2 (pt) * 2017-12-01 2020-11-17 Seattle Genetics, Inc. anticorpos anti-liv1 humanizados para o tratamento de câncer de mama
BR112021008082A2 (pt) 2018-11-07 2021-08-10 Crispr Therapeutics Ag terapia contra o câncer com células imunitárias anti-liv1
US20210228676A1 (en) * 2019-12-09 2021-07-29 Seagen Inc. Combination Therapy With LIV1-ADC and PD-1 Antagonist
JP2023543026A (ja) * 2020-09-28 2023-10-12 シージェン インコーポレイテッド がんの処置のためのヒト化抗liv1抗体
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
WO2024188339A1 (zh) * 2023-03-15 2024-09-19 浙江博锐生物制药有限公司 抗liv-1抗体和抗liv-1抗体药物偶联物及其药物用途
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法

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JP2014506120A (ja) * 2010-12-06 2014-03-13 シアトル ジェネティクス,インコーポレーテッド Liv−1に対するヒト化抗体および癌治療のためのその使用
WO2015002134A1 (ja) * 2013-07-02 2015-01-08 公益財団法人がん研究会 細胞性免疫誘導ワクチン
WO2015155976A1 (ja) * 2014-04-10 2015-10-15 第一三共株式会社 抗her2抗体-薬物コンジュゲート

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