JP2019507113A5 - - Google Patents

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Publication number
JP2019507113A5
JP2019507113A5 JP2018534626A JP2018534626A JP2019507113A5 JP 2019507113 A5 JP2019507113 A5 JP 2019507113A5 JP 2018534626 A JP2018534626 A JP 2018534626A JP 2018534626 A JP2018534626 A JP 2018534626A JP 2019507113 A5 JP2019507113 A5 JP 2019507113A5
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JP
Japan
Prior art keywords
biodegradable
disease
antigen
subject
particles
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2018534626A
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English (en)
Japanese (ja)
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JP2019507113A (ja
JP6904959B2 (ja
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Publication date
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Priority claimed from PCT/US2017/012173 external-priority patent/WO2017120222A1/en
Publication of JP2019507113A publication Critical patent/JP2019507113A/ja
Publication of JP2019507113A5 publication Critical patent/JP2019507113A5/ja
Priority to JP2021105106A priority Critical patent/JP7333360B2/ja
Application granted granted Critical
Publication of JP6904959B2 publication Critical patent/JP6904959B2/ja
Priority to JP2023132166A priority patent/JP7730867B2/ja
Priority to JP2025136021A priority patent/JP2025181835A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018534626A 2016-01-04 2017-01-04 結合エピトープを含有する融合タンパク質を封入する粒子 Active JP6904959B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021105106A JP7333360B2 (ja) 2016-01-04 2021-06-24 結合エピトープを含有する融合タンパク質を封入する粒子
JP2023132166A JP7730867B2 (ja) 2016-01-04 2023-08-14 結合エピトープを含有する融合タンパク質を封入する粒子
JP2025136021A JP2025181835A (ja) 2016-01-04 2025-08-18 結合エピトープを含有する融合タンパク質を封入する粒子

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662274711P 2016-01-04 2016-01-04
US62/274,711 2016-01-04
PCT/US2017/012173 WO2017120222A1 (en) 2016-01-04 2017-01-04 Particles encapsulating fusion proteins containing linked epitopes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021105106A Division JP7333360B2 (ja) 2016-01-04 2021-06-24 結合エピトープを含有する融合タンパク質を封入する粒子

Publications (3)

Publication Number Publication Date
JP2019507113A JP2019507113A (ja) 2019-03-14
JP2019507113A5 true JP2019507113A5 (enExample) 2020-02-06
JP6904959B2 JP6904959B2 (ja) 2021-07-21

Family

ID=59274014

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2018534626A Active JP6904959B2 (ja) 2016-01-04 2017-01-04 結合エピトープを含有する融合タンパク質を封入する粒子
JP2021105106A Active JP7333360B2 (ja) 2016-01-04 2021-06-24 結合エピトープを含有する融合タンパク質を封入する粒子
JP2023132166A Active JP7730867B2 (ja) 2016-01-04 2023-08-14 結合エピトープを含有する融合タンパク質を封入する粒子
JP2025136021A Pending JP2025181835A (ja) 2016-01-04 2025-08-18 結合エピトープを含有する融合タンパク質を封入する粒子

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021105106A Active JP7333360B2 (ja) 2016-01-04 2021-06-24 結合エピトープを含有する融合タンパク質を封入する粒子
JP2023132166A Active JP7730867B2 (ja) 2016-01-04 2023-08-14 結合エピトープを含有する融合タンパク質を封入する粒子
JP2025136021A Pending JP2025181835A (ja) 2016-01-04 2025-08-18 結合エピトープを含有する融合タンパク質を封入する粒子

Country Status (6)

Country Link
US (2) US20190365656A1 (enExample)
EP (1) EP3400069A4 (enExample)
JP (4) JP6904959B2 (enExample)
CA (1) CA3009799A1 (enExample)
IL (2) IL260296B2 (enExample)
WO (1) WO2017120222A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013163176A1 (en) 2012-04-23 2013-10-31 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
CA2907915C (en) 2013-04-03 2023-03-07 Allertein Therapeutics, Llc Immunomodulatory nanoparticle compositions comprising a plurality of nanoparticles comprising biodegradable or biocompatible polymers and hydrophilic and hydrophobic cellular components
EP3247384B1 (en) * 2015-01-14 2023-10-04 The Regents of the University of Colorado, a body corporate In vitro method of diagnosis of type 1 diabetes with insulin mimotopes
GB201508025D0 (en) 2015-05-11 2015-06-24 Ucl Business Plc Fabry disease gene therapy
SG11201808552XA (en) 2016-05-18 2018-10-30 Cue Biopharma Inc T-cell modulatory multimeric polypeptides and methods of use thereof
CN110325205B (zh) 2016-12-22 2023-08-15 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
US11851471B2 (en) 2017-01-09 2023-12-26 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
KR20240005989A (ko) 2017-03-15 2024-01-12 큐 바이오파마, 인크. 면역 반응을 조절하는 방법
CN111566214B (zh) * 2017-07-06 2024-03-08 日东纺绩株式会社 抗人IgG4单克隆抗体及利用该抗体的人IgG4测定试剂
EP3678677A4 (en) * 2017-09-07 2021-06-16 Cue Biopharma, Inc. ANTIGEN-PRESENTING POLYPEPTIDES AND METHOD FOR THEIR USE
WO2019131769A1 (ja) * 2017-12-26 2019-07-04 公立大学法人名古屋市立大学 新規抗pad4抗体
WO2019139896A1 (en) 2018-01-09 2019-07-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
CN110041408B (zh) * 2018-01-16 2021-05-18 华中科技大学 一种小分子多肽及其在制备防治帕金森综合症药物中的应用
CA3102032A1 (en) 2018-06-05 2019-12-12 Anji Pharma (Us) Llc Compositions and methods for treating pancreatitis
EP3807294B1 (en) * 2018-06-13 2026-01-14 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. Peptides having inhibitory activity on muscarinic receptor m3
AU2020316005A1 (en) * 2019-07-19 2022-02-24 The Regents Of The University Of Michigan Compositions and methods for treating autoimmune disorders
EP4138907A4 (en) * 2020-04-20 2024-08-21 The General Hospital Corporation IMMUNOGENIC COMPOSITION OF CORONAVIRUS WITH EPITOPES HAVING HIGH NETWORK SCORE
IL296209A (en) 2020-05-12 2022-11-01 Cue Biopharma Inc Multimeric t-cell modulatory polypeptides and methods of using them
IT202000010888A1 (it) * 2020-05-13 2021-11-13 Consiglio Nazionale Ricerche Nanovescicole di mielina e loro impieghi
JP2023541366A (ja) 2020-09-09 2023-10-02 キュー バイオファーマ, インコーポレイテッド 1型真性糖尿病(t1d)を治療するためのmhcクラスii t細胞調節多量体ポリペプチド及びその使用方法
GB202017119D0 (en) * 2020-10-28 2020-12-09 Oxford Vacmedix Uk Ltd Polypeptides for cancer treatment
IL307722A (en) 2021-04-16 2023-12-01 Cour Pharmaceuticals Dev Company Inc A method of monitoring the existence of immunological tolerance
EP4337322A1 (en) * 2021-05-11 2024-03-20 Oxford Vacmedix UK Ltd. Vaccine formulation comprising recombinant overlapping peptides and native proteins
JPWO2023282293A1 (enExample) * 2021-07-07 2023-01-12
WO2023070104A1 (en) 2021-10-21 2023-04-27 Cour Pharmaceuticals Development Company Inc. Treatment of primary biliary cholangitis (pbc) with tolerizing nanoparticles
AR127755A1 (es) * 2021-11-24 2024-02-28 Cour Pharmaceuticals Dev Company Inc Preparación de nanopartículas que inducen tolerancia para el tratamiento de la alergia al maní
CN118922202A (zh) * 2022-03-24 2024-11-08 尤利乌斯·马克西米利安维尔茨堡大学 MHC Ib介导的胰岛抗原特异性免疫抑制作为1型糖尿病的新型疗法
TW202400801A (zh) 2022-04-29 2024-01-01 美商庫爾製藥發展公司股份有限公司 用於克服治療性載體及蛋白質之免疫原性之耐受性免疫修飾奈米粒子
CN115541872A (zh) * 2022-09-22 2022-12-30 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种pd-l1检测试剂盒及其检测方法
WO2024086706A1 (en) 2022-10-19 2024-04-25 Cour Pharmaceuticals Development Company Inc. Treatment of peanut allergy with tolerizing nanoparticles
CN115771883B (zh) * 2022-11-28 2024-02-23 淮阴工学院 从酿酒酵母发酵液中提取的蛋白酶a在化学法合成纳米硒形貌控制和稳定性影响中的用途
WO2024206202A1 (en) 2023-03-24 2024-10-03 Cour Pharmaceuticals Development Company Inc. Tolerizing immune modifying nanoparticles for myasthenia gravis treatment
KR20260016937A (ko) 2023-05-23 2026-02-04 코어 파마슈티칼스 디벨롭먼트 컴퍼니 인크. 원발성 담즙성 담관염의 치료를 위한 관용화 나노입자의 제조
TW202500576A (zh) 2023-05-25 2025-01-01 美商庫爾製藥發展公司股份有限公司 以免疫耐受性(tolerizing)奈米粒子治療1型糖尿病(t1d)
EP4753730A1 (en) * 2023-08-01 2026-06-10 Diamante Srl Composition and methods for treating multiple sclerosis
WO2025043196A2 (en) * 2023-08-24 2025-02-27 The Trustees Of Indiana University Anti-cancer peptides, and methods and uses thereof
WO2025199149A1 (en) 2024-03-18 2025-09-25 Cour Pharmaceuticals Development Company Inc. Sting agonism for antigen specific tolerance
WO2026019942A2 (en) 2024-07-16 2026-01-22 Cour Pharmaceuticals Development Company Inc. Tolerizing immune modifying nanoparticles for treatment of narcolepsy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1135408T3 (da) * 1998-12-04 2012-01-23 Biogen Idec Inc HBV-kerneantigenpartikler med multipelle immunogene komponenter, som er bundne via peptidligander
CA2410510A1 (en) * 2000-06-02 2001-12-13 Memorial Sloan-Kettering Cancer Center Artificial antigen presenting cells and methods of use thereof
US20060222656A1 (en) * 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
WO2009022236A2 (en) * 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
US8691771B2 (en) * 2010-05-21 2014-04-08 Merrimack Pharmaceuticals, Inc. Bi-specific fusion proteins for tissue repair
US20120070493A1 (en) * 2010-08-23 2012-03-22 Selecta Biosciences, Inc. Targeted multi-epitope dosage forms for induction of an immune response to antigens
MX357202B (es) * 2012-02-16 2018-06-28 Vlp Therapeutics Llc Composicion de particula tipo virus.
KR102283760B1 (ko) * 2012-06-21 2021-08-03 노쓰웨스턴유니버시티 펩티드 접합된 입자
DK3033102T4 (da) * 2013-08-13 2024-02-26 Univ Northwestern Peptidkonjugerede partikler
WO2017139498A1 (en) * 2016-02-09 2017-08-17 Cour Pharmaceuticals Development Company Inc. Timps encapsulating japanese cedar pollen epitopes

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