|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
ATE356869T1
(de)
|
1990-01-12 |
2007-04-15 |
Amgen Fremont Inc |
Bildung von xenogenen antikörpern
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5562909A
(en)
|
1993-07-12 |
1996-10-08 |
Massachusetts Institute Of Technology |
Phosphazene polyelectrolytes as immunoadjuvants
|
|
WO1995006477A1
(en)
|
1993-08-31 |
1995-03-09 |
Gliatech, Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
US6319498B1
(en)
|
1995-03-14 |
2001-11-20 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
|
WO1997021728A1
(en)
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6071493A
(en)
*
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US6043283A
(en)
*
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
NZ333334A
(en)
|
1997-04-17 |
2001-06-29 |
Frank L Sorgi |
Delivery system for gene therapy to the brain
|
|
US7588766B1
(en)
*
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US7790856B2
(en)
*
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6913745B1
(en)
*
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US6923964B1
(en)
*
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
US20080050367A1
(en)
*
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
TWI239847B
(en)
*
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7964192B1
(en)
*
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US7179892B2
(en)
*
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6761888B1
(en)
*
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
JP2003503312A
(ja)
*
|
1999-05-05 |
2003-01-28 |
ニューロシェム インコーポレイテッド |
立体選択的抗原線維形成ペプチドおよびそのペプチド模倣体
|
|
UA81216C2
(en)
*
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
KR20080059676A
(ko)
|
1999-11-29 |
2008-06-30 |
뉴로겜 인터내셔널 리미티드 |
알츠하이머 및 아밀로이드 관련 질병의 예방 및 치료용백신
|
|
SI1257584T2
(sl)
|
2000-02-24 |
2013-07-31 |
Washington University St. Louis |
Humanizirana protitelesa, ki veĹľejo amiloidni peptid beta
|
|
US6686443B1
(en)
|
2000-05-26 |
2004-02-03 |
The Regents Of The University Of California |
Chemical reagents for formation of disulfide bonds in peptides
|
|
WO2002003911A2
(en)
*
|
2000-07-07 |
2002-01-17 |
Lars Lannfelt |
Prevention and treatment of alzheimer's disease
|
|
AU2007234495A1
(en)
*
|
2000-09-08 |
2007-12-06 |
Board Of Regents, The University Of Texas System |
Biopanning and rapid analysis of selective interactive ligands (BRASIL)
|
|
US7700751B2
(en)
*
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
TWI255272B
(en)
*
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2436789A1
(en)
|
2000-12-19 |
2002-08-22 |
Palatin Technologies, Inc. |
Identification of target-specific folding sites in peptides and proteins
|
|
DE10101430B4
(de)
*
|
2001-01-13 |
2008-10-02 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Lösliche cyclische Analoga zur Modulation der Amyloidogenese
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
US7314974B2
(en)
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
MY139983A
(en)
*
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
AU2003250102B2
(en)
*
|
2002-07-24 |
2009-09-17 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
US9535076B2
(en)
|
2002-09-12 |
2017-01-03 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
EA012325B1
(ru)
|
2002-12-24 |
2009-08-28 |
Беллус Хелс (Интернэшнл) Лимитед |
Терапевтические составы для лечения болезней, связанных с наличием бета-амилоида
|
|
WO2004071408A2
(en)
|
2003-02-10 |
2004-08-26 |
Applied Molecular Evolution, Inc. |
Aβ BINDING MOLECULES
|
|
ES2237356T3
(es)
|
2003-04-07 |
2007-04-01 |
Novetide Ltd. |
Procedimiento para la produccion de peptidos ciclicos.
|
|
TWI374893B
(en)
*
|
2003-05-30 |
2012-10-21 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
EP1484336A1
(en)
|
2003-06-02 |
2004-12-08 |
Pevion Biotech Ltd. |
Methods for synthesizing conformationally constrained peptides, peptidometics and the use thereof as synthetic vaccines
|
|
JP2007527865A
(ja)
|
2003-09-12 |
2007-10-04 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
種々の配列を有するタンパク質から形成されたアミロイドに共通の高分子量凝集中間体に特異的なモノクローナル抗体
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
WO2005095633A1
(en)
*
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
US20060129126A1
(en)
|
2004-11-19 |
2006-06-15 |
Kaplitt Michael G |
Infusion device and method for infusing material into the brain of a patient
|
|
WO2006066049A2
(en)
*
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
TW200635607A
(en)
|
2004-12-15 |
2006-10-16 |
Elan Pharm Inc |
Humanized Aβ antibodies for use in improving cognition
|
|
EP1676859A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
*
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
AU2006251832A1
(en)
|
2005-05-27 |
2006-11-30 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
KR20080095836A
(ko)
*
|
2005-11-10 |
2008-10-29 |
로스캄프 리서치 엘엘씨 |
Ａ―베타 펩티드 단편에 의한 혈관형성의 조정
|
|
AR057233A1
(es)
|
2005-12-12 |
2007-11-21 |
Hoffmann La Roche |
Glicosilacion en la region variable
|
|
WO2007103739A2
(en)
|
2006-03-01 |
2007-09-13 |
The University Of Utah Research Foundation |
Methods and compositions related to cyclic peptide synthesis
|
|
US8784810B2
(en)
*
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
KR101605207B1
(ko)
|
2006-07-14 |
2016-03-22 |
에이씨 이뮨 에스.에이. |
아밀로이드 베타에 대해 인간화된 항체
|
|
SI2074145T1
(sl)
|
2006-10-02 |
2017-12-29 |
Ac Immune S.A. |
Humanizirano protitelo proti amiloid beta
|
|
KR101160385B1
(ko)
|
2007-01-18 |
2012-07-10 |
일라이 릴리 앤드 캄파니 |
페길화된 Ａβ ＦＡＢ
|
|
US8003097B2
(en)
*
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
AR066987A1
(es)
|
2007-06-12 |
2009-09-23 |
Ac Immune Sa |
Anticuerpo monoclonal contra proteina beta-amiloide
|
|
PL2170389T3
(pl)
|
2007-06-12 |
2015-03-31 |
Ac Immune Sa |
Humanizowane przeciwciało przeciw amyloidowi beta
|
|
DK2182983T3
(da)
*
|
2007-07-27 |
2014-07-14 |
Janssen Alzheimer Immunotherap |
Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer
|
|
RU2571859C2
(ru)
|
2007-10-05 |
2015-12-20 |
Дженентек, Инк. |
Применение антитела против амилоида-бета при глазных заболеваниях
|
|
CN105169388A
(zh)
|
2007-10-05 |
2015-12-23 |
基因技术公司 |
人源化抗体
|
|
US20090246191A1
(en)
|
2007-10-11 |
2009-10-01 |
University Of Tennessee Research Foundation |
Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
|
|
JO3076B1
(ar)
*
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
MX2010004660A
(es)
*
|
2007-10-29 |
2010-07-30 |
Inserm Inst Nat De La Sante De |
NUEVOS ANTICUERPOS ESPECIFICOS DE LOS PEPTIDOS ß-AMILOIDES Y SUS USOS COMO AGENTES DE DIAGNOSTICO Y DROGAS.
|
|
KR101581733B1
(ko)
|
2007-11-16 |
2015-12-31 |
더 락커펠러 유니버시티 |
원섬유 형태의 베타아밀로이드 단백질에 대해 특이적인 항체
|
|
MX384227B
(es)
|
2007-12-28 |
2025-03-14 |
Univ Tennessee Res Found |
Anticuerpos y fragmentos de unión a antígenos para usarse en el tratamiento y la profilaxis de amiloidosis.
|
|
WO2009143489A2
(en)
*
|
2008-05-22 |
2009-11-26 |
Archer Pharmaceuticals, Inc. |
Modulation of angiogenesis by a-beta peptide fragments
|
|
AT509611B1
(de)
|
2008-06-12 |
2012-04-15 |
Affiris Forschungs-Und Entwicklungs Gmbh |
Vakzin
|
|
CA2723995A1
(en)
|
2008-06-12 |
2009-12-17 |
Affiris Ag |
Compounds for treating symptoms associated with parkinson's disease
|
|
AT506819B1
(de)
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
AU2009266552B2
(en)
*
|
2008-07-01 |
2014-01-23 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vaccine against amyloid folding intermediate
|
|
US9801865B2
(en)
|
2008-09-24 |
2017-10-31 |
The United States Of America As Represented By The Department Of Veteran Affairs |
Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
|
|
EP2172485A1
(en)
|
2008-10-01 |
2010-04-07 |
Pierre Fabre Medicament |
Novel anti CXCR4 antibodies and their use for the treatment of cancer
|
|
EP2342220B1
(en)
|
2008-10-06 |
2021-05-12 |
The University Of British Columbia |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
*
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
US9090679B2
(en)
|
2009-04-17 |
2015-07-28 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to A beta oligomers and use thereof
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
DK2462161T3
(en)
|
2009-08-06 |
2017-06-06 |
Immunas Pharma Inc |
Antibodies specifically binding to A-beta oligomers and their use
|
|
JP5554528B2
(ja)
*
|
2009-09-08 |
2014-07-23 |
国立大学法人 岡山大学 |
新規アミロイドβ凝集体結合性ペプチドおよび新規アミロイドβ凝集体結合性ペプチドを用いたアミロイド病の検査方法
|
|
JP2013505438A
(ja)
|
2009-09-18 |
2013-02-14 |
プロビオドルグ エージー |
アミロイドβペプチドの検出のための新規アッセイ
|
|
RU2555526C2
(ru)
|
2010-02-26 |
2015-07-10 |
Байоарктик Ньюросайенс Аб |
Антитела, связывающиеся с протофибриллами, и их применение в методах терапии и диагностики болезни паркинсона, деменции, ассоциированной с образованием диффузных телец леви, и других альфа-синуклеинопатий
|
|
US9216217B2
(en)
|
2010-03-03 |
2015-12-22 |
The University Of British Columbia |
Oligomer-specific amyloid beta epitope and antibodies
|
|
WO2011119484A1
(en)
*
|
2010-03-23 |
2011-09-29 |
Iogenetics, Llc |
Bioinformatic processes for determination of peptide binding
|
|
EP2377860A1
(en)
|
2010-04-16 |
2011-10-19 |
AC Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
DK2558446T5
(da)
|
2010-04-16 |
2019-12-09 |
Ac Immune Sa |
Nye forbindelser til behandling af sygdomme associerede med amyloid- eller amyloidlignende proteiner
|
|
US9320793B2
(en)
|
2010-07-14 |
2016-04-26 |
Acumen Pharmaceuticals, Inc. |
Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42
|
|
US9221900B2
(en)
|
2010-07-30 |
2015-12-29 |
Ac Immune S.A. |
Methods for identifying safe and functional humanized antibodies
|
|
EP3533803B1
(en)
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antibodies
|
|
WO2012051498A2
(en)
|
2010-10-15 |
2012-04-19 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
FR2966827B1
(fr)
*
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
US20120321694A1
(en)
*
|
2010-10-27 |
2012-12-20 |
Daniel Larocque |
Compositions and uses
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
EP2511296A1
(en)
|
2011-04-12 |
2012-10-17 |
Araclón Biotech, S. L. |
Antibody, kit and method for determination of amyloid peptides
|
|
GB201113570D0
(en)
*
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
AU2012335014A1
(en)
*
|
2011-11-10 |
2014-06-19 |
Cangene U.S., Incorporated |
Compositions and methods for treating Alzheimer's disease
|
|
EP2659908A1
(en)
|
2012-05-01 |
2013-11-06 |
Affiris AG |
Compositions
|
|
FR2993265B1
(fr)
|
2012-07-16 |
2014-11-21 |
Saint Gobain Isover |
Dispositif de formation de fibres minerales
|
|
WO2014031697A2
(en)
|
2012-08-21 |
2014-02-27 |
The Institute Of Molecular Medicine |
COMPOSITIONS AND METHODS RELATED TO DISEASES ASSOCIATED WITH DEPOSITS OF AMYLOID, TAU, AND α-SYNUCLEIN
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
AU2014305658A1
(en)
|
2013-08-05 |
2016-02-11 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
BR112016004242A8
(pt)
|
2013-08-28 |
2018-06-12 |
Stemcentrx Inc |
Métodos para conjugação sítio-específica de anticorpos e composições
|
|
EP3102611A4
(en)
*
|
2014-02-03 |
2017-08-23 |
Cangene Corporation |
Humanized beta-amyloid binding molecules and uses thereof
|
|
WO2016138525A1
(en)
*
|
2015-02-27 |
2016-09-01 |
University Of Washington |
Polypeptide assemblies and methods for the production thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
SG10202111808WA
(en)
|
2015-08-11 |
2021-11-29 |
Novartis Ag |
5-bromo-2,6-di-(1h-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer
|
|
TW201718028A
(zh)
*
|
2015-10-13 |
2017-06-01 |
賽米克Ｉｐ有限責任公司 |
Ve-鈣黏蛋白結合性生物結合物
|
|
AU2016354688B2
(en)
*
|
2015-11-09 |
2021-12-16 |
The University Of British Columbia |
Epitopes in Amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
JP2019507581A
(ja)
|
2015-11-09 |
2019-03-22 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータのエピトープおよびそれに対する立体配座選択的抗体
|
|
EP3374379A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES
|
|
HK1259324A1
(zh)
|
2015-11-09 |
2019-11-29 |
英属哥伦比亚大学 |
淀粉样蛋白β表位及其抗体
|
|
US11756650B2
(en)
*
|
2015-11-09 |
2023-09-12 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
CN108368160A
(zh)
*
|
2015-11-09 |
2018-08-03 |
英属哥伦比亚大学 |
淀粉样蛋白β中的C-末端表位及其构象选择性抗体
|
|
KR102550991B1
(ko)
|
2016-07-18 |
2023-07-04 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
아밀로이드 베타에 대한 항체
|
|
US20180125920A1
(en)
*
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|