|
US1947085A
(en)
|
1931-09-22 |
1934-02-13 |
Westinghouse Electric & Mfg Co |
Electrical apparatus
|
|
US4133814A
(en)
|
1975-10-28 |
1979-01-09 |
Eli Lilly And Company |
2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
GB8327256D0
(en)
|
1983-10-12 |
1983-11-16 |
Ici Plc |
Steroid derivatives
|
|
DE4126999A1
(de)
|
1991-08-16 |
1993-02-18 |
Basf Ag |
Herbizide mittel, enthaltend 3-aminobenzo(b)thiophene als antidots
|
|
EP0545478A1
(en)
|
1991-12-03 |
1993-06-09 |
MERCK SHARP & DOHME LTD. |
Heterocyclic compounds as tachykinin antagonists
|
|
JPH05345780A
(ja)
*
|
1991-12-24 |
1993-12-27 |
Kumiai Chem Ind Co Ltd |
ピリミジンまたはトリアジン誘導体及び除草剤
|
|
CZ285937B6
(cs)
|
1992-01-16 |
1999-12-15 |
Hoechst Aktiengesellschaft |
Arylcykloalkylové deriváty, způsob přípravy těchto derivátů a jejich použití
|
|
TW366342B
(en)
|
1992-07-28 |
1999-08-11 |
Lilly Co Eli |
The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
|
|
EP0622673B1
(en)
|
1993-04-24 |
1998-02-04 |
Kodak Limited |
Photographic colour couplers and photographic materials containing them
|
|
US5478847A
(en)
|
1994-03-02 |
1995-12-26 |
Eli Lilly And Company |
Methods of use for inhibiting bone loss and lowering serum cholesterol
|
|
US5834468A
(en)
|
1995-07-07 |
1998-11-10 |
Zeneca Limited |
Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists
|
|
US6458811B1
(en)
|
1996-03-26 |
2002-10-01 |
Eli Lilly And Company |
Benzothiophenes formulations containing same and methods
|
|
US5780497A
(en)
|
1996-04-19 |
1998-07-14 |
American Home Products Corporation |
2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents
|
|
TW397821B
(en)
|
1996-04-19 |
2000-07-11 |
American Home Produits Corp |
3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof
|
|
US5998402A
(en)
|
1996-04-19 |
1999-12-07 |
American Home Products Corporation |
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
|
|
US5880137A
(en)
|
1996-04-19 |
1999-03-09 |
American Home Products Corporation |
2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents
|
|
CN1275911A
(zh)
*
|
1997-08-15 |
2000-12-06 |
杜克大学 |
一种预防或治疗雌激素依赖性疾病及失调的方法
|
|
AU9399898A
(en)
|
1997-10-03 |
1999-04-27 |
Eli Lilly And Company |
Benzothiophenes
|
|
US6005102A
(en)
|
1997-10-15 |
1999-12-21 |
American Home Products Corporation |
Aryloxy-alkyl-dialkylamines
|
|
US6326392B1
(en)
|
1997-11-06 |
2001-12-04 |
American Home Products Corporation |
Anti-estrogen plus progestin containing oral contraceptives
|
|
UA68365C2
(en)
|
1997-11-06 |
2004-08-16 |
Wyeth Corp |
Peroral contraception by combination of anti-estrogen and progestin
|
|
US6479535B1
(en)
|
1998-05-15 |
2002-11-12 |
Wyeth |
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
|
|
US6583170B1
(en)
|
1998-05-15 |
2003-06-24 |
Wyeth |
2-Phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol and estrogen formulations
|
|
GB0000313D0
(en)
|
2000-01-10 |
2000-03-01 |
Astrazeneca Uk Ltd |
Formulation
|
|
CO5271697A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona
|
|
CO5271696A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Procedimiento para reducir la morbilidad y el riesgo de mortalidad
|
|
CO5271709A1
(es)
|
2000-01-12 |
2003-04-30 |
Pfizer Prod Inc |
Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
|
|
CO5251465A1
(es)
|
2000-01-26 |
2003-02-28 |
Pfizer Prod Inc |
Composiciones y procedimientos para tratar la osteoporosis y reducir el colesterol
|
|
US7091240B2
(en)
|
2000-03-10 |
2006-08-15 |
Oxigene, Inc. |
Tubulin binding ligands and corresponding prodrug constructs
|
|
US20020013327A1
(en)
|
2000-04-18 |
2002-01-31 |
Lee Andrew G. |
Compositions and methods for treating female sexual dysfunction
|
|
AR030064A1
(es)
|
2000-07-06 |
2003-08-13 |
Wyeth Corp |
Metodos para inhibir los efectos uterotroficos de los agentes estrogenicos
|
|
EP1296674A2
(en)
|
2000-07-06 |
2003-04-02 |
Wyeth |
Use of substituted indole compounds for increasing nitric oxide synthase activity
|
|
AU2001271784A1
(en)
|
2000-07-06 |
2002-01-21 |
Wyeth |
Therapy for prosthesis-related bone degeneration
|
|
US6509332B2
(en)
|
2000-07-06 |
2003-01-21 |
Wyeth |
Methods of treating excessive intraocular pressure
|
|
EP1359940A2
(en)
|
2000-07-06 |
2003-11-12 |
Wyeth |
Combinations of statins, estrogenic agents and optionally estrogens
|
|
JP2004502729A
(ja)
|
2000-07-06 |
2004-01-29 |
ワイス |
Ｓｓｒｉおよびエストロゲン剤の組み合わせ
|
|
AU2001273125A1
(en)
|
2000-07-06 |
2002-01-21 |
American Home Products Corporation |
Combinations of bisphosphonates, estrogenic agents and optionally estrogens
|
|
AU2001271706A1
(en)
|
2000-07-06 |
2002-01-21 |
American Home Products Corporation |
Use of substituted indole compounds for treating breast disorders
|
|
WO2002003988A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for treating neuropeptide y-related conditions
|
|
WO2002003989A2
(en)
|
2000-07-06 |
2002-01-17 |
Wyeth |
Use of substituted indole compounds for treating sphincter incontinence
|
|
EP1177787A3
(en)
|
2000-07-28 |
2003-09-10 |
Pfizer Products Inc. |
Use of an estrogen agonist/antagonist for treating cataracts
|
|
ATE278421T1
(de)
|
2000-08-11 |
2004-10-15 |
Wyeth Corp |
Verfahren zur behandlung eines östrogenrezeptor positives karzinoms
|
|
EP1192945A3
(en)
|
2000-09-21 |
2004-03-03 |
Pfizer Products Inc. |
Use of an estrogen agonist/antagonist for treating osteoarthritis
|
|
IL145838A
(en)
|
2000-10-16 |
2008-11-03 |
Pfizer Prod Inc |
Use of an estrogen agonist/antagonist for the manufacture of a medicament for treating vaginitis
|
|
AU781168B2
(en)
|
2001-01-26 |
2005-05-12 |
Pfizer Products Inc. |
Method of treating certain cancers using an estrogen agonist/antagonist
|
|
AU2003281632A1
(en)
*
|
2002-07-24 |
2004-02-09 |
Eli Lilly And Company |
Dihydro-dibenzo(b,e)oxepine based selective estrogen receptor modulators, compositions and methods
|
|
ATE423122T1
(de)
|
2003-08-15 |
2009-03-15 |
Astrazeneca Ab |
Kondensierte heterocyclen als inhibitoren von glutamatracemase (muri)
|
|
JP2005129430A
(ja)
|
2003-10-27 |
2005-05-19 |
Konica Minolta Holdings Inc |
光電変換材料用半導体、光電変換素子及び太陽電池
|
|
FR2862646B1
(fr)
*
|
2003-11-20 |
2006-02-24 |
Merck Sante Sas |
Nouveaux composes antidiabetiques contenant des derives benzofuranes, benzothiophenes
|
|
RU2365586C2
(ru)
|
2003-12-15 |
2009-08-27 |
Лаборатуар Терамекс |
Производные 1-n-фениламино-1н-имидазола и содержащие их фармацевтические композиции
|
|
US7399767B2
(en)
|
2005-01-21 |
2008-07-15 |
Ortho-Mcneil Pharmaceutical, Inc. |
Heterocyclic benzo[c]chromene derivatives useful as modulators of the estrogen receptors
|
|
CA2597447C
(en)
|
2005-02-14 |
2014-03-25 |
Bionomics Limited |
Novel tubulin polymerisation inhibitors
|
|
CA2640678C
(en)
|
2006-02-03 |
2015-03-31 |
Bionomics Limited |
Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors
|
|
CA2656067C
(en)
|
2006-06-23 |
2014-08-12 |
Radius Health, Inc. |
Treatment of vasomotor symptoms with selective estrogen receptor modulators
|
|
EP1947085A1
(en)
|
2007-01-19 |
2008-07-23 |
Laboratorios del Dr. Esteve S.A. |
Substituted indole sulfonamide compounds, their preparation and use as medicaments
|
|
WO2009013195A1
(en)
|
2007-07-25 |
2009-01-29 |
F. Hoffmann-La Roche Ag |
Benzofuran- and benzo[b]thiophene-2-carboxylic acid amide derivatives and use thereof as histamine 3 receptor modulators
|
|
WO2010093578A1
(en)
|
2009-02-10 |
2010-08-19 |
Glaxo Group Limited |
Indolinyl-, benzofuranyl-, and benzothienyl- amides as modulators of chemokine receptors
|
|
EP2427430B1
(en)
|
2009-05-04 |
2014-09-10 |
The Royal Institution for the Advancement of Learning/McGill University |
5-oxo-ete receptor antagonist compounds
|
|
CN102713618B
(zh)
|
2009-09-16 |
2015-07-15 |
新基阿维罗米克斯研究公司 |
蛋白激酶复合物和抑制剂
|
|
CA2798074A1
(en)
|
2010-04-27 |
2011-11-03 |
The Johns Hopkins University |
Immunogenic compositions and methods for treating neoplasia
|
|
EP3205648A1
(en)
|
2010-06-10 |
2017-08-16 |
Seragon Pharmaceuticals, Inc. |
Estrogen receptor modulators and uses thereof
|
|
US8853423B2
(en)
|
2010-06-17 |
2014-10-07 |
Seragon Pharmaceuticals, Inc. |
Indane estrogen receptor modulators and uses thereof
|
|
US8642632B2
(en)
|
2010-07-02 |
2014-02-04 |
Radius Health, Inc. |
Selective androgen receptor modulators
|
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
|
US10005750B2
(en)
|
2010-10-06 |
2018-06-26 |
J-Pharma Co., Ltd. |
Developing potent urate transporter inhibitors: compounds designed for their uricosuric action
|
|
CA2819299A1
(en)
|
2010-12-24 |
2012-06-28 |
Merck Sharp & Dohme B.V. |
N-substituted azetidine derivatives
|
|
DE102011087987A1
(de)
|
2011-12-08 |
2013-06-13 |
Bayer Intellectual Property Gmbh |
6,7-Dihydro-5H-benzo[7]annulen-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
EP2791132A4
(en)
|
2011-12-14 |
2015-08-05 |
Seragon Pharmaceuticals Inc |
ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
|
|
BR112014014767A2
(pt)
|
2011-12-16 |
2017-06-13 |
Olema Pharmaceuticals Inc |
novos compostos de benzopirano, composições e usos dos mesmos
|
|
MX2014009303A
(es)
|
2012-01-31 |
2014-10-14 |
Novartis Ag |
Combinacion de un inhibidor de rtk con un anti-estrogeno y uso del mismo para el tratamiento de cancer.
|
|
US9499538B2
(en)
|
2012-03-20 |
2016-11-22 |
Seragon Pharmaceuticals, Inc. |
Estrogen receptor modulators and uses thereof
|
|
CN104145514B
(zh)
|
2012-08-01 |
2018-03-13 |
华为技术有限公司 |
用于同步的方法、装置及系统
|
|
US20150203285A1
(en)
|
2012-09-05 |
2015-07-23 |
Kjoninklijke Philips N.V. |
Capsule for the preparation of beverages, device and method
|
|
US20150284357A1
(en)
|
2012-10-24 |
2015-10-08 |
Gregory R. Thatcher |
Compositions and methods for treating estrogen-related medical disorders
|
|
WO2014066692A1
(en)
|
2012-10-24 |
2014-05-01 |
The Board Of Trustees Of The University Of Illinois |
Compositions and methods for treating estrogen-related medical disorders
|
|
NZ710385A
(en)
*
|
2013-02-19 |
2016-10-28 |
Novartis Ag |
Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
|
|
CN105121413B
(zh)
|
2013-03-14 |
2018-09-14 |
赛拉根医药股份有限公司 |
多环雌激素受体调节剂及其用途
|
|
AP2015008858A0
(en)
|
2013-05-28 |
2015-11-30 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2014203129A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Combinations of benzopyran compounds, compositions and uses thereof
|
|
WO2014203132A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Substituted benzopyran compounds, compositions and uses thereof
|
|
BR112015030595A2
(pt)
|
2013-06-19 |
2017-07-25 |
Seragon Pharmaceuticals Inc |
moduladores de receptor de estrogênio de azetidina e usos dos mesmos
|
|
EA031077B1
(ru)
|
2013-06-19 |
2018-11-30 |
Серагон Фармасьютикалз, Инк. |
Модулятор рецептора эстрогена и его применения
|
|
GB201311888D0
(en)
|
2013-07-03 |
2013-08-14 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
WO2015028409A1
(de)
|
2013-08-27 |
2015-03-05 |
Bayer Pharma Aktiengesellschaft |
6,7-dihydro-5h-benzo[7]annulen-derivate, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
MA39740A
(fr)
|
2014-03-13 |
2017-01-18 |
Hoffmann La Roche |
Méthodes et compositions pour moduler des mutants du récepteur des oestrogènes
|
|
SG11201607334YA
(en)
|
2014-03-13 |
2016-10-28 |
Hoffmann La Roche |
Therapeutic combinations with estrogen receptor modulators
|
|
ES2939940T3
(es)
|
2014-03-28 |
2023-04-28 |
Univ Duke |
Tratamiento del cáncer de mama utilizando moduladores selectivos de los receptores de estrógenos
|
|
WO2016097071A1
(en)
|
2014-12-18 |
2016-06-23 |
F. Hoffmann-La Roche Ag |
Estrogen receptor modulators and uses thereof
|
|
TWI784255B
(zh)
|
2014-12-18 |
2022-11-21 |
瑞士商赫孚孟拉羅股份公司 |
四氫-吡啶并[3,4-b]吲哚雌激素受體調節劑及其用途
|
|
CN107406433A
(zh)
|
2014-12-18 |
2017-11-28 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的2,3‑二苯基色烯的衍生物
|
|
WO2016174551A1
(en)
|
2015-04-27 |
2016-11-03 |
Pfizer Inc. |
Anti-estrogenic compounds
|
|
JP6768711B2
(ja)
|
2015-05-26 |
2020-10-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
複素環式エストロゲン受容体モジュレーター及びその使用
|
|
EP3312184A4
(en)
|
2015-06-16 |
2019-02-27 |
Jiangsu Hengrui Medicine Co., Ltd. |
PIPERIDINE DERIVATIVE AND ITS PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF
|
|
WO2017059139A1
(en)
|
2015-10-01 |
2017-04-06 |
Olema Pharmaceuticals, Inc. |
TETRAHYDRO-1H-PYRIDO[3,4-b]INDOLE ANTI-ESTROGENIC DRUGS
|
|
WO2017056115A1
(en)
|
2015-10-03 |
2017-04-06 |
Sun Pharma Advanced Research Company Limited |
Novel n-aryl containing fused heterocyclic compounds
|
|
CN108137511A
(zh)
|
2015-10-07 |
2018-06-08 |
豪夫迈·罗氏有限公司 |
制备(e)-3-(4-((e)-2-(2-氯-4-氟苯基)-1-(1h-吲唑-5-基)丁-1-烯-1-基)苯基)丙烯酸的方法
|
|
US10865199B2
(en)
|
2015-10-27 |
2020-12-15 |
Sun Pharma Advanced Research Company Limited |
Heterocyclic antiestrogens
|
|
JP6920295B2
(ja)
|
2015-11-09 |
2021-08-18 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
テトラヒドロナフタレンエストロゲン受容体モジュレーター及びその使用
|
|
EP3378861B1
(en)
|
2015-11-12 |
2021-08-04 |
Zhejiang Hisun Pharmaceutical Co., Ltd. |
Acrylic acid derivative, preparation method and use in medicine thereof
|
|
DK3386500T3
(da)
*
|
2015-12-09 |
2022-12-12 |
Univ Illinois |
Benzothiophen-baserede selektive østrogenreceptor ned-regulatorer
|
|
WO2018081168A2
(en)
|
2016-10-24 |
2018-05-03 |
The Board Of Trustees Of The University Of Illinois |
Benzothiophene-based selective mixed estrogen receptor downregulators
|
|
JP7229162B2
(ja)
|
2017-01-06 |
2023-02-27 |
ジー１ セラピューティクス， インコーポレイテッド |
癌の治療に対する併用療法
|