|
US2464203A
(en)
|
1943-05-21 |
1949-03-15 |
Boots Pure Drug Co Ltd |
Manufacture of dienoestrol
|
|
US2465505A
(en)
|
1944-12-05 |
1949-03-29 |
Hoffmann La Roche |
Process for the manufacture of 3, 4-di-(p-hydroxy-phenyl)-hexadiene-2, 4
|
|
US2914562A
(en)
|
1957-08-06 |
1959-11-24 |
Wm S Merrell Co |
Amine derivatives of triphenylethanol
|
|
BE637389A
(enExample)
|
1962-09-13 |
|
|
|
|
US3822287A
(en)
|
1969-04-17 |
1974-07-02 |
Rexall Drug Chemical |
Process for preparation of substituted 3,4-(diphenyl)chromans
|
|
US4133814A
(en)
|
1975-10-28 |
1979-01-09 |
Eli Lilly And Company |
2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
|
|
US4230862A
(en)
|
1975-10-28 |
1980-10-28 |
Eli Lilly And Company |
Antifertility compounds
|
|
DE2658307C2
(de)
|
1976-12-22 |
1979-03-15 |
Klinge Pharma Gmbh & Co, 8000 Muenchen |
Di-O'-hydroxyphenyD-alkanverbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
DE2860900D1
(en)
|
1977-08-22 |
1981-11-05 |
Ici Plc |
Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
|
|
DE3046719C2
(de)
|
1980-12-11 |
1983-02-17 |
Klinge Pharma GmbH, 8000 München |
1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
GB2126576B
(en)
|
1982-06-25 |
1985-06-19 |
Farmos Group Limited |
Alkane and alkene derivatives
|
|
US5491173A
(en)
|
1982-06-25 |
1996-02-13 |
Orion-Yhtyma Oy |
Tri-phenyl alkene derivatives and their preparation and use
|
|
GB8327256D0
(en)
|
1983-10-12 |
1983-11-16 |
Ici Plc |
Steroid derivatives
|
|
IE58417B1
(en)
|
1984-04-27 |
1993-09-22 |
Ici Plc |
Chemical derivatives
|
|
GB8517360D0
(en)
|
1985-07-09 |
1985-08-14 |
Erba Farmitalia |
Substituted androsta-1,4-diene-3,17-diones
|
|
US5352795A
(en)
|
1986-03-07 |
1994-10-04 |
Ciba-Geigy Corporation |
Alpha-heterocycle substituted tolunitriles
|
|
DE3762617D1
(de)
|
1986-09-11 |
1990-06-13 |
Nat Res Dev |
Tamoxifenderivate.
|
|
GB8714013D0
(en)
|
1987-06-16 |
1987-07-22 |
Ici Plc |
(substituted-aralkyl)heterocyclic compounds
|
|
US5395842A
(en)
|
1988-10-31 |
1995-03-07 |
Endorecherche Inc. |
Anti-estrogenic compounds and compositions
|
|
US6060503A
(en)
|
1991-12-02 |
2000-05-09 |
Endorecherche, Inc. |
Benzopyran-containing compounds and method for their use
|
|
EP0639567A1
(en)
|
1992-05-08 |
1995-02-22 |
Otsuka Pharmaceutical Factory, Inc. |
Indole derivative
|
|
TW366342B
(en)
|
1992-07-28 |
1999-08-11 |
Lilly Co Eli |
The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
|
|
US6756388B1
(en)
|
1993-10-12 |
2004-06-29 |
Pfizer Inc. |
Benzothiophenes and related compounds as estrogen agonists
|
|
GB9326332D0
(en)
|
1993-12-23 |
1994-02-23 |
Karo Bio |
Indole derivatives
|
|
US5681835A
(en)
|
1994-04-25 |
1997-10-28 |
Glaxo Wellcome Inc. |
Non-steroidal ligands for the estrogen receptor
|
|
DE4426625A1
(de)
|
1994-07-27 |
1996-03-14 |
Schering Ag |
2-Phenylindole, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
US5552412A
(en)
|
1995-01-09 |
1996-09-03 |
Pfizer Inc |
5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis
|
|
IL124881A0
(en)
|
1996-01-11 |
1999-01-26 |
Novo Nordisk As |
Use of the l-enantiomer of centchroman for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of breast cancer
|
|
US5883118A
(en)
|
1996-01-11 |
1999-03-16 |
Nova Nordisk A/S |
Prostatic carcinoma
|
|
WO1997025035A1
(en)
|
1996-01-11 |
1997-07-17 |
Novo Nordisk A/S |
Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms
|
|
US5726202A
(en)
|
1996-01-11 |
1998-03-10 |
Novo Nordisk A/S |
Benign prostatic hypertrophy
|
|
US5985910A
(en)
|
1996-04-19 |
1999-11-16 |
American Home Products Corporation |
3- [4- (2- Phenyl-Indole-1-ylmethyl) Phenyl]- Acrylamides as estrogenic agents
|
|
US5880137A
(en)
|
1996-04-19 |
1999-03-09 |
American Home Products Corporation |
2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents
|
|
US5780497A
(en)
|
1996-04-19 |
1998-07-14 |
American Home Products Corporation |
2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents
|
|
US5998402A
(en)
|
1996-04-19 |
1999-12-07 |
American Home Products Corporation |
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
|
|
DE19635525A1
(de)
|
1996-08-20 |
1998-02-26 |
Schering Ag |
7alpha-(xi-Aminoalkyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha(xi-Aminoalkyl-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
ZA982877B
(en)
|
1997-04-09 |
1999-10-04 |
Lilly Co Eli |
Treatment of central nervous system disorders with selective estrogen receptor modulators.
|
|
ZA982819B
(en)
|
1997-04-09 |
1999-10-04 |
Lilly Co Eli |
Treatment or prophylaxis of prostatic cancer and benign prostatic hyperplasia with selective estrogn receptor modulators.
|
|
ZA982818B
(en)
|
1997-04-09 |
1999-10-04 |
Lilly Co Eli |
Prevention of breast cancer using selective estrogen receptor modulators.
|
|
CA2298651A1
(en)
|
1997-08-07 |
1999-02-18 |
Jeffrey Alan Dodge |
1-¬4-(substituted alkoxy)benzyl|naphthalene compounds having estrogen inhibitory activity
|
|
AR015500A1
(es)
|
1997-12-23 |
2001-05-02 |
Schering Ag |
11 BETA-HALoGENO-ESTRATRIENOS SUSTITUIDOS EN 7 ALFA, PROCEDIMIENTO PARA ELABORAR PREPARADOS FARMACEUTICOS QUE CONTIENEN TALES 11 BETA-HALOGENO-ESTRATRIENOSSUSTITUIDOS EN 7 ALFA, ASI COMO SU UTILIZACION EN LA ELABORACION DE MEDICAMENTOS.
|
|
US6548491B2
(en)
|
1997-12-24 |
2003-04-15 |
Sri International |
Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
|
|
US6054446A
(en)
|
1997-12-24 |
2000-04-25 |
Sri International |
Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
|
|
US6069153A
(en)
|
1998-05-12 |
2000-05-30 |
American Home Products Corporation |
Indenoindoles and benzocarbazoles as estrogenic agents
|
|
EP1102755B1
(en)
|
1998-08-07 |
2006-01-04 |
Chiron Corporation |
Substituted isoxazole derivatives as estrogen receptor modulators
|
|
TW593256B
(en)
|
1999-11-16 |
2004-06-21 |
Hormos Medical Oy Ltd |
Triphenylalkene derivatives and their use as selective estrogen receptor modulators
|
|
US6340774B1
(en)
|
2000-01-31 |
2002-01-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Non-steroidal estrogen-receptor antagonists
|
|
DE10013782A1
(de)
|
2000-03-15 |
2001-10-18 |
Schering Ag |
4-Fluoralkyl-2H-benzopyrane mit antiestrogener Wirksamkeit, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, die diese enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
|
|
WO2001098322A1
(en)
|
2000-06-22 |
2001-12-27 |
Northeastern University |
Novel steroidal antiestrogens and antiandrogens and uses thereof
|
|
US6750213B2
(en)
|
2000-10-19 |
2004-06-15 |
Merck & Co., Inc. |
Estrogen receptor modulators
|
|
CA2430013C
(en)
|
2000-11-30 |
2011-11-22 |
Medarex, Inc. |
Transgenic transchromosomal rodents for making human antibodies
|
|
US6599921B2
(en)
|
2001-02-22 |
2003-07-29 |
Nanodesign, Inc. |
Non-steroidal estrogen receptor ligands
|
|
PL374215A1
(en)
|
2001-08-11 |
2005-10-03 |
Bristol-Myers Squibb Pharma Company |
Selective estrogen receptor modulators
|
|
WO2003015761A1
(en)
|
2001-08-13 |
2003-02-27 |
Merck & Co., Inc. |
Selective estrogen receptor modulators
|
|
DK1501819T3
(da)
|
2002-04-24 |
2011-01-10 |
Merck Sharp & Dohme |
Østrogenreceptormodulatorer
|
|
WO2005087812A1
(en)
|
2004-03-05 |
2005-09-22 |
Ludwig Institute For Cancer Research |
Multivalent antibody materials and methods for vegf/pdgf family of growth factors
|
|
AR051597A1
(es)
|
2004-11-01 |
2007-01-24 |
Merck & Co Inc |
Moduladores de los receptores de estrogeno
|
|
EP2021028A2
(en)
|
2006-04-17 |
2009-02-11 |
Ludwig Institute For Cancer Research |
Methods and compositions for modulation of blood-neural barrier
|
|
WO2008033887A2
(en)
*
|
2006-09-13 |
2008-03-20 |
Nuvelo, Inc. |
Methods for treating cancer
|
|
WO2008099060A2
(en)
|
2007-02-14 |
2008-08-21 |
Hormos Medical Ltd |
Methods for the preparation of fispemifene from ospemifene
|
|
US7732491B2
(en)
*
|
2007-11-12 |
2010-06-08 |
Bipar Sciences, Inc. |
Treatment of breast cancer with a PARP inhibitor alone or in combination with anti-tumor agents
|
|
EP2558098A2
(en)
|
2010-04-16 |
2013-02-20 |
Novartis AG |
Treatment of endocrine resistant breast cancer
|
|
RU2014140116A
(ru)
*
|
2012-04-24 |
2016-06-10 |
Тромбодженикс Н.В. |
Антитела против pdgf-c
|
|
HK1216502A1
(zh)
|
2012-11-02 |
2016-11-18 |
Repros Therapeutics Inc. |
用於癌症治療的反式-克羅米芬
|