ZA982818B - Prevention of breast cancer using selective estrogen receptor modulators. - Google Patents
Prevention of breast cancer using selective estrogen receptor modulators.Info
- Publication number
- ZA982818B ZA982818B ZA9802818A ZA982818A ZA982818B ZA 982818 B ZA982818 B ZA 982818B ZA 9802818 A ZA9802818 A ZA 9802818A ZA 982818 A ZA982818 A ZA 982818A ZA 982818 B ZA982818 B ZA 982818B
- Authority
- ZA
- South Africa
- Prior art keywords
- prevention
- breast cancer
- estrogen receptor
- receptor modulators
- selective estrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4311897P | 1997-04-09 | 1997-04-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA982818B true ZA982818B (en) | 1999-10-04 |
Family
ID=21925594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9802818A ZA982818B (en) | 1997-04-09 | 1998-04-02 | Prevention of breast cancer using selective estrogen receptor modulators. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0975628A4 (en) |
JP (1) | JP2001518897A (en) |
KR (1) | KR20010006215A (en) |
CN (1) | CN1259945A (en) |
AU (1) | AU6957398A (en) |
CA (1) | CA2286207A1 (en) |
EA (1) | EA199900910A1 (en) |
HU (1) | HUP0001845A2 (en) |
ID (1) | ID23653A (en) |
IL (1) | IL132279A0 (en) |
NO (1) | NO994902L (en) |
PL (1) | PL336206A1 (en) |
TR (1) | TR199903244T2 (en) |
WO (1) | WO1998045286A1 (en) |
ZA (1) | ZA982818B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6610706B1 (en) | 1999-07-29 | 2003-08-26 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride |
US6653479B1 (en) | 1999-07-29 | 2003-11-25 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride |
BRPI0818637A2 (en) | 2007-10-16 | 2015-04-07 | Repros Therapeutics Inc | Methods of treating symptom of impaired fasting glucose, metabolic syndrome, metabolic syndrome, and impaired fasting glucose in subjects with secondary or idiopathic hypogonadotropic hypogonadism |
EP2819676B1 (en) | 2012-02-29 | 2018-05-30 | Repros Therapeutics Inc. | Combination therapy for treating androgen deficiency |
DK2958907T3 (en) | 2013-02-19 | 2018-06-06 | Novartis Ag | Thus, benzothiophene derivatives and compositions as selective estrogen receptor degraders |
GB201311888D0 (en) * | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
AU2016352592B2 (en) | 2015-11-10 | 2023-04-27 | Paracrine Therapeutics Ab | Treatment of ER-negative breast cancer with an PDGF-CC inhibitor and an anti estrogen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5510357A (en) * | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
SI0729956T1 (en) * | 1995-02-28 | 2002-04-30 | Eli Lilly And Company | Benzothiophene compounds, intermediates, compositions, and methods |
US5731342A (en) * | 1996-02-22 | 1998-03-24 | Eli Lilly And Company | Benzothiophenes, formulations containing same, and methods |
-
1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/en unknown
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/en unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 CN CN98805957A patent/CN1259945A/en active Pending
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/en unknown
- 1998-04-07 JP JP54309098A patent/JP2001518897A/en active Pending
- 1998-04-07 EA EA199900910A patent/EA199900910A1/en unknown
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/en not_active Application Discontinuation
- 1998-04-07 PL PL98336206A patent/PL336206A1/en unknown
- 1998-04-07 IL IL13227998A patent/IL132279A0/en unknown
- 1998-04-07 ID IDW991189A patent/ID23653A/en unknown
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Application Discontinuation
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
-
1999
- 1999-10-08 NO NO994902A patent/NO994902L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2001518897A (en) | 2001-10-16 |
EA199900910A1 (en) | 2000-04-24 |
NO994902D0 (en) | 1999-10-08 |
ID23653A (en) | 2000-05-11 |
TR199903244T2 (en) | 2000-05-22 |
PL336206A1 (en) | 2000-06-05 |
EP0975628A4 (en) | 2001-03-21 |
IL132279A0 (en) | 2001-03-19 |
CN1259945A (en) | 2000-07-12 |
NO994902L (en) | 1999-12-07 |
WO1998045286A1 (en) | 1998-10-15 |
CA2286207A1 (en) | 1998-10-15 |
KR20010006215A (en) | 2001-01-26 |
AU6957398A (en) | 1998-10-30 |
EP0975628A1 (en) | 2000-02-02 |
HUP0001845A2 (en) | 2001-06-28 |
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