JP2019501936A5 - - Google Patents

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Publication number
JP2019501936A5
JP2019501936A5 JP2018536433A JP2018536433A JP2019501936A5 JP 2019501936 A5 JP2019501936 A5 JP 2019501936A5 JP 2018536433 A JP2018536433 A JP 2018536433A JP 2018536433 A JP2018536433 A JP 2018536433A JP 2019501936 A5 JP2019501936 A5 JP 2019501936A5
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JP
Japan
Prior art keywords
unsubstituted
oxo
diazaspiro
methyl
phenyl
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JP2018536433A
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English (en)
Japanese (ja)
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JP2019501936A (ja
JP6862457B2 (ja
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Priority claimed from PCT/EP2017/025004 external-priority patent/WO2017121646A1/en
Publication of JP2019501936A publication Critical patent/JP2019501936A/ja
Publication of JP2019501936A5 publication Critical patent/JP2019501936A5/ja
Priority to JP2021056938A priority Critical patent/JP7148665B2/ja
Application granted granted Critical
Publication of JP6862457B2 publication Critical patent/JP6862457B2/ja
Expired - Fee Related legal-status Critical Current
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JP2018536433A 2016-01-13 2017-01-13 ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 Expired - Fee Related JP6862457B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021056938A JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16151011.0 2016-01-13
EP16151011 2016-01-13
PCT/EP2017/025004 WO2017121646A1 (en) 2016-01-13 2017-01-13 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021056938A Division JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Publications (3)

Publication Number Publication Date
JP2019501936A JP2019501936A (ja) 2019-01-24
JP2019501936A5 true JP2019501936A5 (https=) 2020-02-27
JP6862457B2 JP6862457B2 (ja) 2021-04-21

Family

ID=55129632

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018536433A Expired - Fee Related JP6862457B2 (ja) 2016-01-13 2017-01-13 ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体
JP2021056938A Active JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021056938A Active JP7148665B2 (ja) 2016-01-13 2021-03-30 ３－（カルボキシメチル）－８－アミノ－２－オキソ－１，３－ジアザ－スピロ－［４．５］－デカン誘導体

Country Status (27)

Country Link
US (7) US20170197919A1 (https=)
EP (2) EP3722283A1 (https=)
JP (2) JP6862457B2 (https=)
KR (1) KR20180100592A (https=)
CN (1) CN108699005B (https=)
AR (1) AR107361A1 (https=)
AU (1) AU2017207467B2 (https=)
BR (1) BR112018014302B1 (https=)
CA (1) CA3011175C (https=)
CL (1) CL2018001913A1 (https=)
CO (1) CO2018008445A2 (https=)
CY (1) CY1122882T1 (https=)
DK (1) DK3402783T3 (https=)
EA (1) EA037649B1 (https=)
EC (1) ECSP18060820A (https=)
ES (1) ES2803354T3 (https=)
HR (1) HRP20200656T1 (https=)
HU (1) HUE049374T2 (https=)
IL (1) IL260495B (https=)
LT (1) LT3402783T (https=)
MX (1) MX379201B (https=)
PL (1) PL3402783T3 (https=)
PT (1) PT3402783T (https=)
RS (1) RS60223B1 (https=)
SI (1) SI3402783T1 (https=)
TW (1) TWI635081B (https=)
WO (1) WO2017121646A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3402784T1 (sl) 2016-01-13 2020-07-31 Gruenenthal Gmbh Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana
SI3402782T1 (sl) 2016-01-13 2020-11-30 Grunenthal Gmbh 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati
CA3011176C (en) 2016-01-13 2023-09-19 Grunenthal Gmbh 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
CA3011180A1 (en) 2016-01-13 2017-07-20 Grunenthal Gmbh 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
BR112018014302B1 (pt) 2016-01-13 2023-10-17 Grünenthal GmbH Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
KR102866751B1 (ko) * 2020-06-09 2025-10-01 삼성디스플레이 주식회사 축합환 화합물을 포함한 발광 소자 및 상기 발광 소자를 포함한 전자 장치
WO2023011422A1 (zh) * 2021-08-02 2023-02-09 上海枢境生物科技有限公司 氧杂螺环类衍生物、制备方法及其用途
US20240400537A1 (en) 2023-04-25 2024-12-05 Gruenenthal Gmbh Cis-8-(3,5-difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2734265B1 (fr) 1995-05-17 1997-06-13 Adir Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant
RU2268883C2 (ru) 2001-04-18 2006-01-27 Эро-Селтик, С.А. Аналоги ноницептина и фармацевтическая композиция на их основе
DE10130020A1 (de) 2001-06-25 2003-12-04 Gruenenthal Gmbh Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate
DE10210195B4 (de) 2002-03-07 2005-12-15 Schwarz Pharma Ag Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
EP1628978A2 (en) 2003-05-23 2006-03-01 Zealand Pharma A/S Triaza-spiro compounds as nociceptin analogues and uses thereof
JO2676B1 (en) 2004-04-06 2012-06-17 جانسين فارماسوتيكا ان. في Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
CN101553474B (zh) 2006-10-19 2013-02-27 霍夫曼-拉罗奇有限公司 作为糖尿病用11b-HSD1抑制剂的咪唑啉酮和咪唑烷酮衍生物
CA2683598C (en) 2007-04-09 2015-11-17 Janssen Pharmaceutica Nv 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression
CA2719735A1 (en) * 2008-03-27 2009-10-01 Gruenenthal Gmbh Substituted 4-aminocyclohexane derivatives
TWI582092B (zh) 2010-07-28 2017-05-11 歌林達股份有限公司 順式－四氫－螺旋（環己烷－１,１’－吡啶［３,４－b］吲哚）－４－胺－衍生物
WO2014106238A1 (en) * 2012-12-31 2014-07-03 Fang, Qun, Kevin Heterocyclic compounds and methods of use thereof
WO2015192039A1 (en) 2014-06-13 2015-12-17 Purdue Pharma L.P. Heterocyclic morphinan derivatives and use thereof
BR112018014302B1 (pt) 2016-01-13 2023-10-17 Grünenthal GmbH Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
CA3011180A1 (en) 2016-01-13 2017-07-20 Grunenthal Gmbh 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
SI3402782T1 (sl) 2016-01-13 2020-11-30 Grunenthal Gmbh 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati
SI3402784T1 (sl) 2016-01-13 2020-07-31 Gruenenthal Gmbh Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana

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