JP2019501940A5 - - Google Patents
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- Publication number
- JP2019501940A5 JP2019501940A5 JP2018536503A JP2018536503A JP2019501940A5 JP 2019501940 A5 JP2019501940 A5 JP 2019501940A5 JP 2018536503 A JP2018536503 A JP 2018536503A JP 2018536503 A JP2018536503 A JP 2018536503A JP 2019501940 A5 JP2019501940 A5 JP 2019501940A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxo
- diazaspiro
- phenyl
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16151014.4 | 2016-01-13 | ||
| EP16151014 | 2016-01-13 | ||
| PCT/EP2017/025007 WO2017121649A1 (en) | 2016-01-13 | 2017-01-13 | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501940A JP2019501940A (ja) | 2019-01-24 |
| JP2019501940A5 true JP2019501940A5 (https=) | 2020-02-20 |
| JP6854823B2 JP6854823B2 (ja) | 2021-04-07 |
Family
ID=55129635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536503A Expired - Fee Related JP6854823B2 (ja) | 2016-01-13 | 2017-01-13 | ３−（カルボキシメチル）−８−アミノ−２−オキソ−１，３−ジアザ−スピロ−［４．５］−デカン誘導体 |
Country Status (28)
| Country | Link |
|---|---|
| US (7) | US20170197971A1 (https=) |
| EP (1) | EP3402785B1 (https=) |
| JP (1) | JP6854823B2 (https=) |
| KR (1) | KR20180097733A (https=) |
| CN (1) | CN108779075B (https=) |
| AR (1) | AR107358A1 (https=) |
| AU (1) | AU2017206910B2 (https=) |
| BR (1) | BR112018014296B1 (https=) |
| CA (1) | CA3011180A1 (https=) |
| CL (1) | CL2018001910A1 (https=) |
| CO (1) | CO2018008449A2 (https=) |
| CY (1) | CY1122892T1 (https=) |
| DK (1) | DK3402785T3 (https=) |
| EA (1) | EA034904B1 (https=) |
| EC (1) | ECSP18060864A (https=) |
| ES (1) | ES2793384T3 (https=) |
| HR (1) | HRP20200809T1 (https=) |
| HU (1) | HUE049134T2 (https=) |
| IL (1) | IL260497B (https=) |
| LT (1) | LT3402785T (https=) |
| MX (1) | MX378995B (https=) |
| PL (1) | PL3402785T3 (https=) |
| PT (1) | PT3402785T (https=) |
| RS (1) | RS60224B1 (https=) |
| SI (1) | SI3402785T1 (https=) |
| TW (1) | TWI640514B (https=) |
| WO (1) | WO2017121649A1 (https=) |
| ZA (1) | ZA201805358B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3402784T1 (sl) | 2016-01-13 | 2020-07-31 | Gruenenthal Gmbh | Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana |
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| CA3011176C (en) | 2016-01-13 | 2023-09-19 | Grunenthal Gmbh | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| CA3011180A1 (en) | 2016-01-13 | 2017-07-20 | Grunenthal Gmbh | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| BR112018014302B1 (pt) | 2016-01-13 | 2023-10-17 | Grünenthal GmbH | Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| WO2019039855A2 (ko) | 2017-08-22 | 2019-02-28 | 주식회사 엘지화학 | 방열 소재의 혼합 방법 |
| US20240400537A1 (en) | 2023-04-25 | 2024-12-05 | Gruenenthal Gmbh | Cis-8-(3,5-difluorophenyl)-8-(dimethylamino)-1,3-diazaspiro[4.5]decan-2-one derivatives |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2734265B1 (fr) | 1995-05-17 | 1997-06-13 | Adir | Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant |
| RU2268883C2 (ru) | 2001-04-18 | 2006-01-27 | Эро-Селтик, С.А. | Аналоги ноницептина и фармацевтическая композиция на их основе |
| DE10130020A1 (de) | 2001-06-25 | 2003-12-04 | Gruenenthal Gmbh | Substituierte 1-Oxa-2,8-diaza-spiro[4.5]dec-2-en-derivate |
| DE10210195B4 (de) | 2002-03-07 | 2005-12-15 | Schwarz Pharma Ag | Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz |
| DK1519939T5 (da) | 2002-07-05 | 2011-01-24 | Targacept Inc | N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf |
| DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| EP1628978A2 (en) | 2003-05-23 | 2006-03-01 | Zealand Pharma A/S | Triaza-spiro compounds as nociceptin analogues and uses thereof |
| JO2676B1 (en) | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
| DE102005023784A1 (de) | 2005-05-19 | 2006-11-30 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005044813A1 (de) | 2005-05-19 | 2007-10-04 | Grünenthal GmbH | Substituierte Spiro-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102005030051A1 (de) | 2005-06-27 | 2006-12-28 | Grünenthal GmbH | Substituierte 1-Oxa-3,8-diazaspiro[4,5]-decan-2-on-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
| DE102006019597A1 (de) | 2006-04-27 | 2007-10-31 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| CN101553474B (zh) | 2006-10-19 | 2013-02-27 | 霍夫曼-拉罗奇有限公司 | 作为糖尿病用11b-HSD1抑制剂的咪唑啉酮和咪唑烷酮衍生物 |
| CA2683598C (en) | 2007-04-09 | 2015-11-17 | Janssen Pharmaceutica Nv | 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression |
| CA2719735A1 (en) * | 2008-03-27 | 2009-10-01 | Gruenenthal Gmbh | Substituted 4-aminocyclohexane derivatives |
| TW201038572A (en) | 2009-03-25 | 2010-11-01 | Gruenenthal Gmbh | Substituted spiro-amide compounds |
| WO2010151815A2 (en) | 2009-06-25 | 2010-12-29 | Abbott Laboratories | 3,9-diazaspiro[5,5]undecane amides and ureas and methods of use thereof |
| TWI582092B (zh) * | 2010-07-28 | 2017-05-11 | 歌林達股份有限公司 | 順式－四氫－螺旋（環己烷－１,１’－吡啶［３,４－b］吲哚）－４－胺－衍生物 |
| WO2015192039A1 (en) * | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Heterocyclic morphinan derivatives and use thereof |
| AR107354A1 (es) | 2016-01-13 | 2018-04-18 | Bristol Myers Squibb Co | Salicilamidas espiroheptanos y compuestos relacionados como inhibidores de rock |
| BR112018014302B1 (pt) | 2016-01-13 | 2023-10-17 | Grünenthal GmbH | Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| SI3402811T1 (sl) | 2016-01-13 | 2022-06-30 | Novo Nordisk A/S | Analogi EGF(A) z maščobnokislinskimi substituenti |
| CA3011180A1 (en) | 2016-01-13 | 2017-07-20 | Grunenthal Gmbh | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| CA3011176C (en) | 2016-01-13 | 2023-09-19 | Grunenthal Gmbh | 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| SI3402782T1 (sl) | 2016-01-13 | 2020-11-30 | Grunenthal Gmbh | 8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati |
| SI3402784T1 (sl) | 2016-01-13 | 2020-07-31 | Gruenenthal Gmbh | Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana |
-
2017
- 2017-01-13 CA CA3011180A patent/CA3011180A1/en active Pending
- 2017-01-13 KR KR1020187021555A patent/KR20180097733A/ko active Pending
- 2017-01-13 ES ES17702003T patent/ES2793384T3/es active Active
- 2017-01-13 DK DK17702003.9T patent/DK3402785T3/da active
- 2017-01-13 HR HRP20200809TT patent/HRP20200809T1/hr unknown
- 2017-01-13 WO PCT/EP2017/025007 patent/WO2017121649A1/en not_active Ceased
- 2017-01-13 BR BR112018014296-4A patent/BR112018014296B1/pt not_active IP Right Cessation
- 2017-01-13 EA EA201891612A patent/EA034904B1/ru not_active IP Right Cessation
- 2017-01-13 JP JP2018536503A patent/JP6854823B2/ja not_active Expired - Fee Related
- 2017-01-13 US US15/405,919 patent/US20170197971A1/en not_active Abandoned
- 2017-01-13 PL PL17702003T patent/PL3402785T3/pl unknown
- 2017-01-13 CN CN201780006526.2A patent/CN108779075B/zh not_active Expired - Fee Related
- 2017-01-13 SI SI201730265T patent/SI3402785T1/sl unknown
- 2017-01-13 TW TW106101126A patent/TWI640514B/zh not_active IP Right Cessation
- 2017-01-13 PT PT177020039T patent/PT3402785T/pt unknown
- 2017-01-13 RS RS20200532A patent/RS60224B1/sr unknown
- 2017-01-13 MX MX2018008646A patent/MX378995B/es unknown
- 2017-01-13 LT LTEP17702003.9T patent/LT3402785T/lt unknown
- 2017-01-13 AU AU2017206910A patent/AU2017206910B2/en not_active Ceased
- 2017-01-13 AR ARP170100093A patent/AR107358A1/es unknown
- 2017-01-13 HU HUE17702003A patent/HUE049134T2/hu unknown
- 2017-01-13 EP EP17702003.9A patent/EP3402785B1/en active Active
-
2018
- 2018-05-15 US US15/980,181 patent/US20180282341A1/en not_active Abandoned
- 2018-07-09 IL IL260497A patent/IL260497B/en active IP Right Grant
- 2018-07-13 CL CL2018001910A patent/CL2018001910A1/es unknown
- 2018-08-10 ZA ZA2018/05358A patent/ZA201805358B/en unknown
- 2018-08-13 CO CONC2018/0008449A patent/CO2018008449A2/es unknown
- 2018-08-13 EC ECSENADI201860864A patent/ECSP18060864A/es unknown
- 2018-12-07 US US16/212,723 patent/US20190106430A1/en not_active Abandoned
-
2019
- 2019-06-27 US US16/454,489 patent/US10807989B2/en active Active
-
2020
- 2020-05-11 CY CY20201100430T patent/CY1122892T1/el unknown
- 2020-08-31 US US17/007,557 patent/US20200399280A1/en not_active Abandoned
-
2021
- 2021-03-01 US US17/188,884 patent/US20210179627A1/en not_active Abandoned
-
2023
- 2023-01-30 US US18/103,319 patent/US20230174540A1/en not_active Abandoned
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