JP2022550353A5 - - Google Patents
Info
- Publication number
- JP2022550353A5 JP2022550353A5 JP2022519331A JP2022519331A JP2022550353A5 JP 2022550353 A5 JP2022550353 A5 JP 2022550353A5 JP 2022519331 A JP2022519331 A JP 2022519331A JP 2022519331 A JP2022519331 A JP 2022519331A JP 2022550353 A5 JP2022550353 A5 JP 2022550353A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- methyl
- naphthyridine
- trans
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019108296 | 2019-09-26 | ||
| CNPCT/CN2019/108296 | 2019-09-26 | ||
| PCT/CN2020/117487 WO2021057853A1 (en) | 2019-09-26 | 2020-09-24 | Aza-quinoline compounds and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022550353A JP2022550353A (ja) | 2022-12-01 |
| JP2022550353A5 true JP2022550353A5 (https=) | 2023-08-22 |
| JP7763753B2 JP7763753B2 (ja) | 2025-11-04 |
Family
ID=75166744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022519331A Active JP7763753B2 (ja) | 2019-09-26 | 2020-09-24 | アザキノリン化合物およびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12544374B2 (https=) |
| EP (1) | EP4034535B1 (https=) |
| JP (1) | JP7763753B2 (https=) |
| KR (1) | KR102889562B1 (https=) |
| CN (1) | CN114746414B (https=) |
| AU (1) | AU2020355837B2 (https=) |
| CA (1) | CA3150284A1 (https=) |
| DK (1) | DK4034535T3 (https=) |
| IL (1) | IL291499B2 (https=) |
| WO (1) | WO2021057853A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7763753B2 (ja) | 2019-09-26 | 2025-11-04 | ノバルティス アーゲー | アザキノリン化合物およびその使用 |
| AR123185A1 (es) * | 2020-08-10 | 2022-11-09 | Novartis Ag | Compuestos y composiciones para inhibir ezh2 |
| AU2022412837A1 (en) * | 2021-12-16 | 2024-06-13 | Teijin Pharma Limited | Cdk9 inhibitor and use thereof |
| CN117384153A (zh) * | 2022-07-12 | 2024-01-12 | 上海赛岚生物科技有限公司 | 一类甲基转移酶抑制剂及其用途 |
| CN118515653B (zh) * | 2024-07-23 | 2024-12-10 | 西湖制药(杭州)有限公司 | 一种ezh2特异性抑制剂及其制备方法和用途 |
| CN118598873B (zh) * | 2024-08-07 | 2024-11-19 | 艾斯拓康生物医药(天津)有限公司 | 一种手性的氮杂-喹啉类化合物的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2779780A (en) | 1955-03-01 | 1957-01-29 | Du Pont | 1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation |
| EP0647450A1 (en) | 1993-09-09 | 1995-04-12 | BEHRINGWERKE Aktiengesellschaft | Improved prodrugs for enzyme mediated activation |
| EP1143957A3 (en) | 1998-12-16 | 2002-02-27 | Warner-Lambert Company | Treatment of arthritis with mek inhibitors |
| JP3811775B2 (ja) | 2000-07-19 | 2006-08-23 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | ４−ヨードフェニルアミノベンズヒドロキサム酸の酸素化エステル |
| CN1653059A (zh) | 2002-03-08 | 2005-08-10 | 卫材株式会社 | 用作医药品的大环化合物 |
| KR100984595B1 (ko) | 2002-03-13 | 2010-09-30 | 어레이 바이오파마 인크. | Ｍｅｋ 억제제로서의 ｎ3 알킬화 벤즈이미다졸 유도체 |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| CA2618218C (en) | 2005-07-21 | 2015-06-30 | Ardea Biosciences, Inc. | N-(arylamino)-sulfonamide inhibitors of mek |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| EP2205242B1 (en) | 2007-09-12 | 2015-04-15 | Genentech, Inc. | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use |
| JP5348725B2 (ja) | 2007-10-25 | 2013-11-20 | ジェネンテック， インコーポレイテッド | チエノピリミジン化合物の製造方法 |
| US8168784B2 (en) | 2008-06-20 | 2012-05-01 | Abbott Laboratories | Processes to make apoptosis promoters |
| WO2014155301A1 (en) | 2013-03-26 | 2014-10-02 | Piramal Enterprises Limited | Substituted bicyclic compounds as inhibitors of ezh2 |
| UY36462A (es) | 2014-12-23 | 2016-07-29 | Novartis Ag | Compuestos de triazolopirimidina y usos de los mismos |
| UY36758A (es) | 2015-06-30 | 2016-12-30 | Glaxosmithkline Ip No 2 Ltd | Inhibidores del potenciador del homólogo zeste 2 |
| WO2017221092A1 (en) | 2016-06-20 | 2017-12-28 | Novartis Ag | Triazolopyridine compounds and uses thereof |
| EP3472166A1 (en) | 2016-06-20 | 2019-04-24 | Novartis AG | Imidazopyrimidine compounds useful for the treatment of cancer |
| KR20190084063A (ko) | 2016-10-28 | 2019-07-15 | 이칸 스쿨 오브 메디슨 엣 마운트 시나이 | Ｅｚｈ２-매개성 암 치료용 조성물 및 방법 |
| JP7763753B2 (ja) | 2019-09-26 | 2025-11-04 | ノバルティス アーゲー | アザキノリン化合物およびその使用 |
-
2020
- 2020-09-24 JP JP2022519331A patent/JP7763753B2/ja active Active
- 2020-09-24 CA CA3150284A patent/CA3150284A1/en active Pending
- 2020-09-24 KR KR1020227011716A patent/KR102889562B1/ko active Active
- 2020-09-24 DK DK20868772.3T patent/DK4034535T3/da active
- 2020-09-24 US US17/632,990 patent/US12544374B2/en active Active
- 2020-09-24 AU AU2020355837A patent/AU2020355837B2/en active Active
- 2020-09-24 EP EP20868772.3A patent/EP4034535B1/en active Active
- 2020-09-24 WO PCT/CN2020/117487 patent/WO2021057853A1/en not_active Ceased
- 2020-09-24 CN CN202080067448.9A patent/CN114746414B/zh active Active
- 2020-09-24 IL IL291499A patent/IL291499B2/en unknown
-
2025
- 2025-11-21 US US19/396,743 patent/US20260076968A1/en active Pending
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