JP2023538159A5 - - Google Patents
Info
- Publication number
- JP2023538159A5 JP2023538159A5 JP2022530800A JP2022530800A JP2023538159A5 JP 2023538159 A5 JP2023538159 A5 JP 2023538159A5 JP 2022530800 A JP2022530800 A JP 2022530800A JP 2022530800 A JP2022530800 A JP 2022530800A JP 2023538159 A5 JP2023538159 A5 JP 2023538159A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- methyl
- methylquinoline
- cyclohexyl
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020108213 | 2020-08-10 | ||
| CNPCT/CN2020/108213 | 2020-08-10 | ||
| PCT/CN2021/111910 WO2022033492A1 (en) | 2020-08-10 | 2021-08-10 | Quinoline compounds and compositions for inhibiting ezh2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023538159A JP2023538159A (ja) | 2023-09-07 |
| JP2023538159A5 true JP2023538159A5 (https=) | 2024-08-16 |
| JP7768880B2 JP7768880B2 (ja) | 2025-11-12 |
Family
ID=77520462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530800A Active JP7768880B2 (ja) | 2020-08-10 | 2021-08-10 | Ｅｚｈ２を阻害するためのキノリン化合物および組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12473273B2 (https=) |
| EP (1) | EP4041725B1 (https=) |
| JP (1) | JP7768880B2 (https=) |
| KR (1) | KR20230051116A (https=) |
| CN (2) | CN114555589B (https=) |
| AR (1) | AR123185A1 (https=) |
| AU (1) | AU2021323828A1 (https=) |
| CA (1) | CA3180139A1 (https=) |
| ES (1) | ES2985111T3 (https=) |
| IL (1) | IL297332B2 (https=) |
| TW (1) | TWI910207B (https=) |
| WO (1) | WO2022033492A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR123185A1 (es) | 2020-08-10 | 2022-11-09 | Novartis Ag | Compuestos y composiciones para inhibir ezh2 |
| CA3243621A1 (en) * | 2022-02-01 | 2023-08-10 | Eli Lilly And Company | METHODS FOR PREPARING SELECTIVE ESTROGEN RECEPTOR DEGRADING AGENTS |
| CN117384153A (zh) * | 2022-07-12 | 2024-01-12 | 上海赛岚生物科技有限公司 | 一类甲基转移酶抑制剂及其用途 |
| CN118515653B (zh) * | 2024-07-23 | 2024-12-10 | 西湖制药(杭州)有限公司 | 一种ezh2特异性抑制剂及其制备方法和用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2779780A (en) | 1955-03-01 | 1957-01-29 | Du Pont | 1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation |
| EP0647450A1 (en) | 1993-09-09 | 1995-04-12 | BEHRINGWERKE Aktiengesellschaft | Improved prodrugs for enzyme mediated activation |
| EP1143957A3 (en) | 1998-12-16 | 2002-02-27 | Warner-Lambert Company | Treatment of arthritis with mek inhibitors |
| JP3811775B2 (ja) | 2000-07-19 | 2006-08-23 | ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー | ４−ヨードフェニルアミノベンズヒドロキサム酸の酸素化エステル |
| CN1653059A (zh) | 2002-03-08 | 2005-08-10 | 卫材株式会社 | 用作医药品的大环化合物 |
| KR100984595B1 (ko) | 2002-03-13 | 2010-09-30 | 어레이 바이오파마 인크. | Ｍｅｋ 억제제로서의 ｎ3 알킬화 벤즈이미다졸 유도체 |
| SE0202134D0 (sv) * | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Therapeutic agents |
| JP2006124387A (ja) * | 2004-09-30 | 2006-05-18 | Taisho Pharmaceut Co Ltd | 新規なキノリン、テトラヒドロキナゾリン、及びピリミジン誘導体と、これらを使用することに関連した治療方法 |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| CA2618218C (en) | 2005-07-21 | 2015-06-30 | Ardea Biosciences, Inc. | N-(arylamino)-sulfonamide inhibitors of mek |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| EP2205242B1 (en) | 2007-09-12 | 2015-04-15 | Genentech, Inc. | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use |
| JP5348725B2 (ja) | 2007-10-25 | 2013-11-20 | ジェネンテック， インコーポレイテッド | チエノピリミジン化合物の製造方法 |
| US8168784B2 (en) | 2008-06-20 | 2012-05-01 | Abbott Laboratories | Processes to make apoptosis promoters |
| US20130310379A1 (en) * | 2010-11-19 | 2013-11-21 | Constellation Pharmaceuticals | Modulators of methyl modifying enzymes, compositions and uses thereof |
| TN2016000529A1 (en) * | 2014-06-17 | 2018-04-04 | Pfizer | Substituted dihydroisoquinolinone compounds |
| EP3472166A1 (en) * | 2016-06-20 | 2019-04-24 | Novartis AG | Imidazopyrimidine compounds useful for the treatment of cancer |
| CN110621316B (zh) * | 2017-04-21 | 2024-01-26 | Epizyme股份有限公司 | 用ehmt2抑制剂进行的组合疗法 |
| CN109912576B (zh) * | 2019-03-20 | 2021-11-19 | 华东理工大学 | 环状或螺环二胺类嘧啶-异羟肟酸及其用途 |
| JP7763753B2 (ja) * | 2019-09-26 | 2025-11-04 | ノバルティス アーゲー | アザキノリン化合物およびその使用 |
| AR123185A1 (es) | 2020-08-10 | 2022-11-09 | Novartis Ag | Compuestos y composiciones para inhibir ezh2 |
-
2021
- 2021-08-09 AR ARP210102216A patent/AR123185A1/es unknown
- 2021-08-10 IL IL297332A patent/IL297332B2/en unknown
- 2021-08-10 JP JP2022530800A patent/JP7768880B2/ja active Active
- 2021-08-10 CA CA3180139A patent/CA3180139A1/en active Pending
- 2021-08-10 CN CN202180005903.7A patent/CN114555589B/zh active Active
- 2021-08-10 WO PCT/CN2021/111910 patent/WO2022033492A1/en not_active Ceased
- 2021-08-10 US US17/919,490 patent/US12473273B2/en active Active
- 2021-08-10 KR KR1020227019646A patent/KR20230051116A/ko active Pending
- 2021-08-10 CN CN202411371645.6A patent/CN119431341A/zh active Pending
- 2021-08-10 AU AU2021323828A patent/AU2021323828A1/en active Pending
- 2021-08-10 ES ES21762334T patent/ES2985111T3/es active Active
- 2021-08-10 TW TW110129535A patent/TWI910207B/zh active
- 2021-08-10 EP EP21762334.7A patent/EP4041725B1/en active Active
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