JP2019500907A5 - - Google Patents

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JP2019500907A5
JP2019500907A5 JP2018554648A JP2018554648A JP2019500907A5 JP 2019500907 A5 JP2019500907 A5 JP 2019500907A5 JP 2018554648 A JP2018554648 A JP 2018554648A JP 2018554648 A JP2018554648 A JP 2018554648A JP 2019500907 A5 JP2019500907 A5 JP 2019500907A5
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sequence
taa
mva
recombinant
pharmaceutical composition
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JP2018554648A
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JP7150611B2 (ja
JP2019500907A (ja
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Priority claimed from PCT/US2017/012704 external-priority patent/WO2017120577A1/en
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Priority to JP2022153352A priority Critical patent/JP2022185011A/ja
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Publication of JP7150611B2 publication Critical patent/JP7150611B2/ja
Priority to JP2024019248A priority patent/JP2024056839A/ja
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JP2018554648A 2016-01-08 2017-01-09 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法 Active JP7150611B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022153352A JP2022185011A (ja) 2016-01-08 2022-09-27 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
JP2024019248A JP2024056839A (ja) 2016-01-08 2024-02-13 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662276479P 2016-01-08 2016-01-08
US62/276,479 2016-01-08
US201662301885P 2016-03-01 2016-03-01
US62/301,885 2016-03-01
PCT/US2017/012704 WO2017120577A1 (en) 2016-01-08 2017-01-09 Compositions and methods for generating an immune response to a tumor associated antigen

Related Child Applications (1)

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JP2022153352A Division JP2022185011A (ja) 2016-01-08 2022-09-27 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法

Publications (3)

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JP2019500907A JP2019500907A (ja) 2019-01-17
JP2019500907A5 true JP2019500907A5 (enExample) 2020-01-30
JP7150611B2 JP7150611B2 (ja) 2022-10-11

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JP2018554648A Active JP7150611B2 (ja) 2016-01-08 2017-01-09 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
JP2022153352A Ceased JP2022185011A (ja) 2016-01-08 2022-09-27 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
JP2024019248A Ceased JP2024056839A (ja) 2016-01-08 2024-02-13 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法

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JP2022153352A Ceased JP2022185011A (ja) 2016-01-08 2022-09-27 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
JP2024019248A Ceased JP2024056839A (ja) 2016-01-08 2024-02-13 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法

Country Status (9)

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US (3) US11278607B2 (enExample)
EP (1) EP3402802B1 (enExample)
JP (3) JP7150611B2 (enExample)
CN (2) CN116064669A (enExample)
AU (2) AU2017206102C1 (enExample)
CA (1) CA3011014A1 (enExample)
ES (1) ES2944314T3 (enExample)
PL (1) PL3402802T3 (enExample)
WO (1) WO2017120577A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2944314T3 (es) 2016-01-08 2023-06-20 Geovax Inc Composiciones y procedimientos para generar una respuesta inmunitaria frente a un antígeno asociado a un tumor
US20190030157A1 (en) 2016-02-03 2019-01-31 Geovax Inc. Compositions and Methods for Generating an Immune Response to a Flavivirus
US20210220469A1 (en) * 2017-08-25 2021-07-22 Geovax, Inc. Immuno-Oncology Compositions and Methods for Use Thereof
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
WO2020073045A1 (en) * 2018-10-05 2020-04-09 Nantcell, Inc. Cd40 and cd40l combo in an adenovirus vaccine vehicle
IL293012A (en) * 2019-11-20 2022-07-01 Bavarian Nordic As Medicinal uses of 4-1bbl modified ankara virus vaccinia ((recombinant mva
KR20220154114A (ko) * 2020-02-14 2022-11-21 지오박스, 인크. 백신 및 SARS-CoV2에 대한 면역 반응을 유도하기 위한 그의 용도
JP7584763B2 (ja) * 2020-06-04 2024-11-18 東亞合成株式会社 抗ウイルス性ペプチドおよびその利用

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787901A (fr) 1971-09-11 1972-12-18 Freistaat Bayern Represente Pa Vaccin antivariolique
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
AU570940B2 (en) 1982-11-30 1988-03-31 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Process for producing poxvirus recombinants for expression offoreign genes
US7045313B1 (en) 1982-11-30 2006-05-16 The United States Of America As Represented By The Department Of Health And Human Services Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA
GB8508845D0 (en) 1985-04-04 1985-05-09 Hoffmann La Roche Vaccinia dna
US5445953A (en) 1991-08-26 1995-08-29 Immuno Aktiengesellschaft Direct molecular cloning of a modified poxvirus genome
ATE181108T1 (de) 1991-08-26 1999-06-15 Immuno Ag Direkt molekuläre klonierung eines modifizierten genoms eines chordopocken-virus
EP1380651A2 (en) 1991-08-26 2004-01-14 Baxter Healthcare S.A. Recombinant fowlpox virus with intact FPV-tk-gene
WO1994012617A1 (en) 1992-11-25 1994-06-09 International Biotechnology Laboratories, Inc. Hepatitis b virus vaccines
UA68327C2 (en) 1995-07-04 2004-08-16 Gsf Forschungszentrum Fur Unwe A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals
WO1998008539A1 (en) 1996-08-26 1998-03-05 Chiron Corporation Postinfection human immunodeficiency virus (hiv) vaccination therapy
US6962708B1 (en) 1997-02-28 2005-11-08 Acambis, Inc. Chimeric flavivirus vaccines
AUPP380598A0 (en) 1998-05-29 1998-06-25 Commonwealth Scientific And Industrial Research Organisation Genetically manipulated entomopoxvirus
US6294176B1 (en) 1998-07-10 2001-09-25 Schering-Plough Veterinary Corp. Recombinant raccoonpox virus and uses thereof as a vaccine in mammalian and avian species
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
AU2002211948B2 (en) 2000-03-02 2007-09-13 Emory University DNA expression vectors and methods of use
WO2002072754A2 (en) 2001-03-08 2002-09-19 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mva expressing modified hiv envelope, gag, and pol genes
EP1279404A1 (en) 2001-07-26 2003-01-29 Istituto Superiore di Sanità Use of HIV-1 tat, fragments or derivatives thereof, to target or to activate antigen-presenting cells, to deliver cargo molecules for vaccination or to treat other diseases
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US7211378B2 (en) * 2002-01-31 2007-05-01 Wisconsin Alumni Research Foundation Filovirus vectors and noninfectious filovirus-based particles
WO2003078640A2 (en) 2002-03-15 2003-09-25 Baxter International Inc. Recombinant drug-sensitive vaccinia virus as smallpox vaccine
KR101138067B1 (ko) 2002-05-16 2012-04-24 버베리안 노딕 에이/에스 수두 바이러스 게놈내로 삽입된 상동 유전자를 발현하는 재조합 수두 바이러스
US20060088909A1 (en) 2002-05-17 2006-04-27 Compans Richard W Virus-like particles, methods of preparation, and immunogenic compositions
US9045727B2 (en) 2002-05-17 2015-06-02 Emory University Virus-like particles, methods of preparation, and immunogenic compositions
WO2003106648A2 (en) 2002-06-14 2003-12-24 Diadexus, Inc. Compositions and methods relating to breast specific genes and proteins
DE10249390A1 (de) 2002-10-23 2004-05-13 Ruprecht-Karls-Universität Heidelberg Rekombinante MVA-Stämme als potentielle Impfstoffe gegen P.falciparum-Malaria
KR20050083839A (ko) 2002-11-25 2005-08-26 버베리안 노딕 에이/에스 두개 이상의 우두 ati 프로모터를 포함하는 재조합폭스바이러스
US20040109876A1 (en) 2002-11-25 2004-06-10 Kureha Chemical Industry Co., Ltd. Vaccine composition, HIV-infection suppression factor and method for the vaccination against HIV
JP5052893B2 (ja) 2003-02-20 2012-10-17 アメリカ合衆国 ポックスベクターにおける新規の挿入部位
EP1518932A1 (en) * 2003-09-29 2005-03-30 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Modified vaccinia virus Ankara (MVA) mutant and use thereof
US20060099225A1 (en) 2004-04-13 2006-05-11 Sina Bavari Generation of virus-like particles and use as panfilovirus vaccine
CA2837748C (en) 2004-05-25 2016-03-08 Oregon Health And Science University Siv and hiv vaccination using rhcmv-and hcmv-based vaccine vectors
EP2319860A3 (en) 2004-08-27 2011-06-15 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Recombinant MVA viruses expressing clade A/G, clade B, and clade C modified HIV env, gag and pol genes
EP1683870A1 (en) 2005-01-24 2006-07-26 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vaccines based on the use of MVA
CA2610292C (en) * 2005-03-30 2015-06-02 Minerva Biotechnologies Corporation Proliferation of muc1 expressing cells
US20060286074A1 (en) 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
ES2281252B1 (es) 2005-07-27 2009-02-16 Consejo Superior De Investigaciones Cientificas Vectores recombinantes basados en el virus modificado de ankara (mva) como vacunas preventivas y terapeuticas contra el sida.
ES2611975T3 (es) 2006-06-20 2017-05-11 Transgene S.A. Procedimiento para producir poxvirus y composiciones de poxvirus
EP2041323A4 (en) 2006-07-13 2009-10-28 Univ Emory VIROSOMES, METHODS OF PREPARATION AND IMMUNOGENIC COMPOSITIONS
EP2062023B2 (en) 2006-08-25 2016-11-09 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services Intergenic sites between conserved genes in the genome of modified vaccinia ankara (mva) vaccinia virus
US20090092628A1 (en) 2007-03-02 2009-04-09 James Mullins Conserved-element vaccines and methods for designing conserved-element vaccines
EP2152730A4 (en) 2007-05-02 2011-08-03 Univ Emory ENLARGEMENT OF GLYCOPROTEININCORPORATION IN VIRUSUAL PARTICLES
EP2468763B1 (en) 2007-05-31 2014-06-18 Academisch Ziekenhuis Leiden h.o.d.n. LUMC HPV epitopes targeted by T cells infiltrating cervical malignancies for use in vaccines
US11202775B2 (en) * 2007-09-25 2021-12-21 Minerva Biotechnologies Corporation Methods for treatment of cancer
WO2009079564A2 (en) 2007-12-17 2009-06-25 Emory University Immunogenic compositions and methods of use thereof
US20110262483A1 (en) 2008-11-03 2011-10-27 Ligocyte Pharmaceuticals, Inc. Methods for isolating enveloped virus-based vlps free of infectious agents
EP2478103A4 (en) 2009-09-16 2014-02-19 Univ Tulane LASSAVIRUS-like PARTICLES AND METHOD FOR THE PRODUCTION THEREOF
AP2012006258A0 (en) 2009-10-13 2012-06-30 Geovax Inc Eliciting immune responses using recombinant MVA viruses expressing HIV ENV, GAG and POL antigens.
DK2488649T3 (da) 2009-10-16 2019-06-17 Us Health Rekombinant modificeret vaccinia ankara (mva)-vaccinia-virus indeholdende restrukturerede insertionssteder
EP2529227B1 (en) 2010-01-27 2015-10-07 Oregon Health & Science University Cytomegalovirus-based immunogenic preparations
CA2790426A1 (en) 2010-02-18 2011-08-25 Emory University Vectors expressing hiv antigens and gm-csf and related methods for generating an immune response
US20120052082A1 (en) 2010-04-09 2012-03-01 Zetra Biologicals, LLC Cross-protective influenza vaccine
TR201902214T4 (tr) 2010-04-16 2019-03-21 Glaxosmithkline Biologicals Sa Şempanze adenoviral vektörü-bazlı filovirüs aşıları.
CN103209701B (zh) 2010-06-11 2016-08-03 乔治亚大学研究基金公司 免疫原性疫苗
AU2012212463B2 (en) * 2011-01-31 2016-07-07 Nanotherapeutics, Inc. Recombinant viral vectors and methods for inducing a heterosubtypic immune response to influenza A viruses
CN103945863A (zh) 2011-08-01 2014-07-23 爱默蕾大学 包含配体的vlp及其相关方法
WO2013059498A1 (en) 2011-10-18 2013-04-25 Geovax, Inc. Mva vectors expressing polypeptides and having high level production in certain cell lines
US9463238B2 (en) 2011-12-09 2016-10-11 Bavarian Nordic A/S Recombinant poxvirus vector comprising tetanus toxin fragment C
CN104853770A (zh) 2012-07-06 2015-08-19 诺华股份有限公司 免疫原性组合物及其应用
WO2014111733A1 (en) 2013-01-21 2014-07-24 Isis Innovation Limited Composition and uses thereof
WO2015009946A1 (en) 2013-07-17 2015-01-22 Emory University Method of increasing immune response to hiv antigens
AU2014340201B2 (en) 2013-10-23 2019-02-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HLA-A24 agonist epitopes of MUC1-C oncoprotein and compositions and methods of use
WO2015066715A1 (en) * 2013-11-04 2015-05-07 Viracell Advanced Products, Llc Virus-like particles and methods related thereto
JP2017515841A (ja) 2014-05-13 2017-06-15 バヴァリアン・ノルディック・アクティーゼルスカブ 腫瘍抗原を発現するポックスウイルス及びtim−3に対するモノクローナル抗体を用いた癌治療のための併用療法
KR102812180B1 (ko) * 2014-09-03 2025-05-23 버베리안 노딕 에이/에스 재조합 변형된 백시니아 바이러스 앙카라 (mva) 필로바이러스 백신
WO2016068919A1 (en) 2014-10-29 2016-05-06 Geovax, Inc. Combination therapy for treating viral reservoirs
WO2016115116A1 (en) 2015-01-12 2016-07-21 Geovax, Inc. Compositions and methods for generating an immune response to a hemorrhagic fever virus
US10072058B2 (en) 2015-04-29 2018-09-11 Emory University Chimeric virus-like particles incorporating fusion GPI anchored GM-CSF and IL-4 conjugates
ES2944314T3 (es) * 2016-01-08 2023-06-20 Geovax Inc Composiciones y procedimientos para generar una respuesta inmunitaria frente a un antígeno asociado a un tumor
US20190030157A1 (en) 2016-02-03 2019-01-31 Geovax Inc. Compositions and Methods for Generating an Immune Response to a Flavivirus
EP3416978A4 (en) 2016-02-16 2019-11-06 Geovax, Inc. MULTIVALENT HIV VACCINE BOOST COMPOSITION AND METHOD OF USE
CA3026054A1 (en) 2016-05-30 2017-12-07 Geovax Inc. Compositions and methods for generating an immune response to hepatitis b virus
WO2018195447A1 (en) 2017-04-20 2018-10-25 Geovax Labs, Inc. Recombinant mva-based hiv immunogens and uses thereof
US20200171141A1 (en) 2017-07-18 2020-06-04 Geovax, Inc. Compositions and Methods for Generating an Immune Response to LASV
US20210220469A1 (en) 2017-08-25 2021-07-22 Geovax, Inc. Immuno-Oncology Compositions and Methods for Use Thereof
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
WO2020247547A1 (en) 2019-06-03 2020-12-10 Geovax, Inc. Cancer vaccine compositions and methods for use thereof

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