AU2017206102C1 - Compositions and methods for generating an immune response to a tumor associated antigen - Google Patents

Compositions and methods for generating an immune response to a tumor associated antigen Download PDF

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AU2017206102C1
AU2017206102C1 AU2017206102A AU2017206102A AU2017206102C1 AU 2017206102 C1 AU2017206102 C1 AU 2017206102C1 AU 2017206102 A AU2017206102 A AU 2017206102A AU 2017206102 A AU2017206102 A AU 2017206102A AU 2017206102 C1 AU2017206102 C1 AU 2017206102C1
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acid sequence
nucleic acid
mva
sequence
taa
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AU2017206102A1 (en
AU2017206102B2 (en
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Arban Domi
Farshad Guirakhoo
Michael Hellerstein
Nathanael Paul McCurley
Harriet Robinson
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Geovax Inc
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Geovax Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001156—Tyrosinase and tyrosinase related proteinases [TRP-1 or TRP-2]
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001169—Tumor associated carbohydrates
    • A61K39/00117—Mucins, e.g. MUC-1
    • A—HUMAN NECESSITIES
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    • A61K39/001181—Alpha-feto protein
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    • A61K39/001182—Carcinoembryonic antigen [CEA]
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • A61K2039/53—DNA (RNA) vaccination
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
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    • C12N2760/14011—Filoviridae
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    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
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    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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AU2017206102A 2016-01-08 2017-01-09 Compositions and methods for generating an immune response to a tumor associated antigen Active AU2017206102C1 (en)

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US201662276479P 2016-01-08 2016-01-08
US62/276,479 2016-01-08
US201662301885P 2016-03-01 2016-03-01
US62/301,885 2016-03-01
PCT/US2017/012704 WO2017120577A1 (en) 2016-01-08 2017-01-09 Compositions and methods for generating an immune response to a tumor associated antigen

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EP (1) EP3402802B1 (enExample)
JP (3) JP7150611B2 (enExample)
CN (2) CN109071592B (enExample)
AU (2) AU2017206102C1 (enExample)
CA (1) CA3011014A1 (enExample)
ES (1) ES2944314T3 (enExample)
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WO2017136419A1 (en) 2016-02-03 2017-08-10 Geovax Inc. Compositions and methods for generating an immune response to a flavivirus
WO2019040846A1 (en) * 2017-08-25 2019-02-28 Geovax Inc. IMMUNO-ONCOLOGY COMPOSITIONS AND METHODS OF USE THEREOF
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
CN113056479A (zh) * 2018-10-05 2021-06-29 南特细胞公司 腺病毒疫苗媒介物中的cd40和cd40l结合物
CN114929268A (zh) * 2019-11-20 2022-08-19 巴法里安诺迪克有限公司 4-1bbl辅助的重组修饰的安卡拉痘苗病毒(mva)的医疗用途
EP4103231A4 (en) * 2020-02-14 2024-03-27 Geovax, Inc. VACCINES AND THEIR USES TO INDUCE AN IMMUNE RESPONSE AGAINST SARS-COV2
JP7584763B2 (ja) * 2020-06-04 2024-11-18 東亞合成株式会社 抗ウイルス性ペプチドおよびその利用

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