JP2018538531A5 - - Google Patents

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JP2018538531A5
JP2018538531A5 JP2018526662A JP2018526662A JP2018538531A5 JP 2018538531 A5 JP2018538531 A5 JP 2018538531A5 JP 2018526662 A JP2018526662 A JP 2018526662A JP 2018526662 A JP2018526662 A JP 2018526662A JP 2018538531 A5 JP2018538531 A5 JP 2018538531A5
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assay
microfluidic device
capture structure
polymer network
situ generation
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JP7083752B2 (ja
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JP2018526662A 2015-12-08 2016-12-07 マイクロ流体デバイス、そのキット、及びその使用方法 Active JP7083752B2 (ja)

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JP2022089508A JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

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US201562264665P 2015-12-08 2015-12-08
US62/264,665 2015-12-08
US201662333821P 2016-05-09 2016-05-09
US62/333,821 2016-05-09
US201662418625P 2016-11-07 2016-11-07
US62/418,625 2016-11-07
PCT/US2016/065426 WO2017100347A1 (en) 2015-12-08 2016-12-07 Microfluidic devices and kits and methods for use thereof

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JP2018538531A JP2018538531A (ja) 2018-12-27
JP2018538531A5 true JP2018538531A5 (enExample) 2021-04-08
JP7083752B2 JP7083752B2 (ja) 2022-06-13

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JP2022089508A Pending JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

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US (3) US10705082B2 (enExample)
EP (2) EP3387438B1 (enExample)
JP (2) JP7083752B2 (enExample)
KR (2) KR102466814B1 (enExample)
CN (2) CN108603878A (enExample)
AU (1) AU2016365724B2 (enExample)
CA (1) CA3005077C (enExample)
DK (1) DK3387438T3 (enExample)
IL (2) IL259837B2 (enExample)
SG (1) SG11201804275TA (enExample)
TW (2) TWI847100B (enExample)
WO (1) WO2017100347A1 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180085783A (ko) 2015-11-23 2018-07-27 버클리 라잇츠, 인크. 인 시츄-생성된 미세유체 격리 구조체들, 키트들, 및 그 이용 방법들
JP6985289B2 (ja) 2016-04-15 2021-12-22 バークレー ライツ，インコーポレイテッド ペン内アッセイの方法、システム及びキット
EP3551745A4 (en) 2016-12-12 2020-07-15 Xcella Biosciences, Inc. SCREENING METHODS AND SYSTEMS USING MICROCAPILLARY NETWORKS
CN110382439B (zh) 2016-12-30 2026-07-21 埃克切拉生物科学公司 多级样品回收系统
US11879034B2 (en) * 2017-03-08 2024-01-23 Regents Of The University Of Michigan Functionalization of polymer scaffolds
JP7227162B2 (ja) 2017-06-06 2023-02-21 ザイマージェン インコーポレイテッド 真菌株を改良するためのｈｔｐゲノム操作プラットフォーム
KR102480894B1 (ko) * 2017-08-01 2022-12-23 일루미나, 인코포레이티드 뉴클레오티드 서열분석용 하이드로겔 비드
DE102017121914A1 (de) * 2017-09-21 2019-03-21 Endress+Hauser Conducta Gmbh+Co. Kg Sensorelement und Verfahren zum Herstellen eines Sensorelements
WO2019075476A2 (en) 2017-10-15 2019-04-18 Berkeley Lights, Inc. METHODS, SYSTEMS AND KITS FOR ENCLOSED TESTS
TWI652658B (zh) 2017-12-12 2019-03-01 奇景光電股份有限公司 晶片以及使用其的電子裝置
WO2019133874A1 (en) * 2017-12-31 2019-07-04 Berkeley Lights, Inc. General functional assay
CA3067140C (en) 2018-02-13 2023-03-21 Illumina, Inc. Dna sequencing using hydrogel beads
CA3067181A1 (en) 2018-04-20 2019-10-24 Illumina, Inc. Methods of encapsulating single cells, the encapsulated cells and uses thereof
WO2019236848A1 (en) 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
US20210162413A1 (en) * 2018-06-18 2021-06-03 Hewlett-Packard Development Company, L.P. Microfluidic immunoassays
CN113195085B (zh) * 2018-10-11 2024-04-19 伯克利之光生命科技公司 用于识别优化蛋白产生的系统和方法以及其试剂盒
CN111036315B (zh) * 2018-10-15 2021-09-21 京东方科技集团股份有限公司 一种微量样品的生成方法及生成芯片
MY202795A (en) 2018-10-26 2024-05-22 Illumina Inc Modulating polymer beads for dna processing
EP3874265A4 (en) * 2018-11-01 2022-09-28 Berkeley Lights, Inc. Methods for assaying biological cells in a microfluidic device
DK3890876T3 (da) 2018-12-06 2024-07-22 Xcella Biosciences Inc Lateral påfyldning af mikrokapillære arrays
JP7231923B2 (ja) * 2019-01-15 2023-03-02 国立大学法人東京工業大学 複合体の検出方法、並びにそれに用いる担体及び検出キット
WO2020160472A1 (en) * 2019-02-01 2020-08-06 Sentilus Holdco, Llc High-sensitivity assay
CN110054146B (zh) * 2019-03-18 2021-08-24 北京航空航天大学 一种周期性v型微柱结构复合膜及其制备方法与应用
EP3962652A4 (en) 2019-04-30 2023-01-18 Berkeley Lights, Inc. CELL ENCAPSULATION AND ANALYSIS PROCESSES
US11668676B2 (en) * 2019-05-30 2023-06-06 The Regents Of The University Of California Microfluidic acoustic devices and methods
WO2021067401A1 (en) * 2019-09-30 2021-04-08 University Of Florida Research Foundation, Incorporated Use of ganglioside 2 and 3 for circulating sarcoma cell detection
CA3156776A1 (en) 2019-11-08 2021-05-14 xCella Biosciences, Inc. Apparatus and methods for laser-based single cell recovery from microcapillary arrays
CA3157616A1 (en) 2019-11-17 2021-05-20 Darshan THAKER Systems and methods for analyses of biological samples
CN111046607B (zh) * 2019-12-12 2025-05-13 浙江清华柔性电子技术研究院 柔性微流体器件设计方法及柔性微流体器件
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
EP4247575A4 (en) * 2020-11-17 2024-10-30 xBiologix, Inc. CONFIGURABLE SUBSTRATE OF A FLUIDIC DEVICE
US12377415B2 (en) 2020-12-30 2025-08-05 The Trustees Of The University Of Pennsylvania Photoactivated selective release (PHASR) of droplets from microwell arrays
TW202248635A (zh) * 2021-04-06 2022-12-16 美商伯克利之光生命科技公司 微流體分析與來自非哺乳動物細胞之生物生產的方法及用於其之套組
WO2023107539A1 (en) * 2021-12-10 2023-06-15 Bio-Rad Laboratories, Inc. Compositions, methods, and systems for sample processing with morphology-adjustable functionalized particles
EP4469207A4 (en) * 2022-01-25 2025-12-31 Bruker Cellular Analysis Inc METHODS FOR DOSING MICRO-OBJECTS IN A MICROFLUID DEVICE
US12669417B2 (en) 2022-03-28 2026-06-30 Bruker Spatial Biology, Inc. Method for assaying a micro-object within a microfluidic device
WO2024108068A2 (en) * 2022-11-17 2024-05-23 Bruker Cellular Analysis, Inc. Methods of evaluating virus-producing cells
WO2025068547A1 (en) * 2023-09-28 2025-04-03 Zhen Zhang A microfluidic device, a microfluidic system and a method for the capture and controllable release of single biological cells
CN118416975A (zh) * 2024-02-19 2024-08-02 杭州联川生物技术股份有限公司 一种微流控芯片加工方法

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387707B1 (en) 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
US6251691B1 (en) 1996-04-25 2001-06-26 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
WO2000046595A1 (en) 1999-02-03 2000-08-10 Aclara Biosciences, Inc. Multichannel control in microfluidics
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US6942776B2 (en) 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
CN100402850C (zh) 1999-06-28 2008-07-16 加利福尼亚技术学院 微型制造的弹性体的阀和泵系统
EP1214630A2 (en) 1999-07-23 2002-06-19 The Board Of Trustees Of The University Of Illinois Microfabricated devices and method of manufacturing the same
EP1254249B1 (en) 1999-12-20 2007-06-20 The Penn State Research Foundation Deposited thin films and their use in detection, attachment, and bio-medical applications
US20030007894A1 (en) 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
AU2002230524A1 (en) * 2000-11-16 2002-05-27 California Institute Of Technology Apparatus and methods for conducting assays and high throughput screening
ITTO20010411A1 (it) 2001-05-02 2002-11-02 Silicon Biosystems S R L Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti.
US20030175947A1 (en) 2001-11-05 2003-09-18 Liu Robin Hui Enhanced mixing in microfluidic devices
US7312085B2 (en) 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
JP4228114B2 (ja) * 2002-05-07 2009-02-25 独立行政法人科学技術振興機構 微小物体の回収方法及び装置
US6958132B2 (en) 2002-05-31 2005-10-25 The Regents Of The University Of California Systems and methods for optical actuation of microfluidics based on opto-electrowetting
DE10224352A1 (de) * 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
US7790443B2 (en) 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
CN101613660B (zh) * 2002-12-30 2013-05-15 加州大学评议会 检测和分析病原体的方法和设备
JP2006512092A (ja) 2002-12-30 2006-04-13 ザ・リージェンツ・オブ・ジ・ユニバーシティ・オブ・カリフォルニア 病原体の検出および分析のための方法および装置
WO2004065618A2 (en) 2003-01-16 2004-08-05 Thermogenic Imaging Methods and devices for monitoring cellular metabolism in microfluidic cell-retaining chambers
EP1615721B1 (en) 2003-04-03 2014-06-18 Fluidigm Corporation Microfluidic devices and methods of using same
US20060240548A1 (en) 2003-06-26 2006-10-26 Mordechai Deutsch Materials for constructing cell-chips, cell-chip covers, cell-chips coats, processed cell-chips and uses thereof
US20050164402A1 (en) 2003-07-14 2005-07-28 Belisle Christopher M. Sample presentation device
EP1664265A4 (en) 2003-07-21 2009-11-25 Seng Entpr Ltd IMPROVED MULTIPLAY PLATE
US20060194306A1 (en) * 2003-08-25 2006-08-31 Herr Amy E System for gel electrophoretic immunoassay
JP4328168B2 (ja) 2003-10-02 2009-09-09 ソニー株式会社 毛細管現象を利用する物質間の相互作用検出部と該検出部を用いる方法及びバイオアッセイ用基板
WO2005040403A1 (en) 2003-10-29 2005-05-06 Agency For Science, Technology And Research Method for detecting analytes by means of an analyte/polymeric activator bilayer arrangement
WO2005072399A2 (en) 2004-01-29 2005-08-11 Massachusetts Institute Of Technology Microscale sorting cytometer
WO2005080606A1 (en) 2004-02-18 2005-09-01 Xiaochuan Zhou Fluidic devices and methods for multiplex chemical and biochemical reactions
US20050221473A1 (en) 2004-03-30 2005-10-06 Intel Corporation Sensor array integrated circuits
WO2005100541A2 (en) 2004-04-12 2005-10-27 The Regents Of The University Of California Optoelectronic tweezers for microparticle and cell manipulation
US7935479B2 (en) 2004-07-19 2011-05-03 Cell Biosciences, Inc. Methods and devices for analyte detection
US7258990B2 (en) * 2004-08-19 2007-08-21 Biocept, Inc. Alleviation of non-specific binding in microarray assays
CA2585002A1 (en) 2004-10-25 2006-05-04 University Of Washington Rapid microfluidic assay for analyte interactions
US20060091015A1 (en) 2004-11-01 2006-05-04 Applera Corporation Surface modification for non-specific adsorption of biological material
US20060237080A1 (en) * 2005-02-15 2006-10-26 Sangyong Jon Patterned surfaces and polymeric microstructures within robust microfluidic channels
JP2006308332A (ja) 2005-04-26 2006-11-09 Moritex Corp 固定反応物質と液体反応物質との反応用フローセル及び反応装置並びに反応装置の運転方法
TWI265864B (en) 2005-05-20 2006-11-11 Univ Nat Cheng Kung Hydrophilic surface structure of non-hydrophilic substrate and fabricating method for the same
EP3029135B1 (en) 2005-07-07 2021-03-17 The Regents of the University of California Apparatus for cell culture array
EP1915467A2 (en) 2005-08-19 2008-04-30 The Regents of the University of California Microfluidic methods for diagnostics and cellular analysis
EP1951742A4 (en) 2005-10-27 2011-06-01 Life Technologies Corp OPTOELECTRONIC SEPARATION OF BIOMOLECULES
TW200734641A (en) * 2005-12-26 2007-09-16 Inst Of Microchemical Technology Microchip for immunoassay, kit for immunoassay and immunoassay method
US20090011486A1 (en) * 2006-01-12 2009-01-08 Massachusetts Institute Of Technology Biodegradable Elastomers
WO2007092713A2 (en) 2006-02-02 2007-08-16 Trustees Of The University Of Pennsylvania Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease
US8124015B2 (en) 2006-02-03 2012-02-28 Institute For Systems Biology Multiplexed, microfluidic molecular assay device and assay method
WO2007092571A2 (en) 2006-02-07 2007-08-16 Wafergen, Inc. Temperature-regulated culture plates
US20150107995A1 (en) 2006-04-18 2015-04-23 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods for Manipulating Beads
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
WO2010048279A2 (en) * 2008-10-21 2010-04-29 Massachusetts Institute Of Technology Lock-release polymerization
US7790631B2 (en) 2006-11-21 2010-09-07 Intel Corporation Selective deposition of a dielectric on a self-assembled monolayer-adsorbed metal
US20080153134A1 (en) 2006-12-22 2008-06-26 Willy Wiyatno Methods and apparatus for generating hydrophilic patterning of high density microplates using an amphiphilic polymer
WO2008083323A1 (en) 2006-12-29 2008-07-10 Invitrogen Corporation Detection apparatus
EP2125219B1 (en) 2007-01-19 2016-08-10 Fluidigm Corporation High precision microfluidic devices and methods
US8685344B2 (en) 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
WO2008119066A1 (en) 2007-03-28 2008-10-02 The Regents Of The University Of California Single-sided lateral-field and phototransistor-based optoelectronic tweezers
WO2008131048A2 (en) * 2007-04-16 2008-10-30 Cellpoint Diagnotics, Inc. Devices and methods for diagnosing, prognosing, or theranosing a condition by enriching rare cells
WO2008147530A1 (en) 2007-05-24 2008-12-04 The Regents Of The University Of California Integrated fluidics devices with magnetic sorting
WO2009021232A2 (en) 2007-08-09 2009-02-12 Massachusetts Institute Of Technology High-throughput, whole-animal screening system
WO2009061392A1 (en) 2007-11-05 2009-05-14 President And Fellows Of Harvard College Forming gel structures using microfluidic channels
EP2212437A4 (en) 2007-11-07 2011-09-28 Univ British Columbia MICROFLUIDIC DEVICE AND METHOD OF USING THE DEVICE
EP2279238A2 (en) 2008-04-21 2011-02-02 Cell Kinetics, Ltd. Flat cell carriers with cell traps
CN101275114A (zh) 2008-04-22 2008-10-01 北京大学 一种微流细胞培养阵列及其应用
KR100991752B1 (ko) 2008-07-15 2010-11-03 한국과학기술원 단일 평면 광전자 소자를 이용한 미세입자 구동장치 및구동방법
GB2464300A (en) 2008-10-10 2010-04-14 Univ Dublin City Microfluidic multiplexed cellular and molecular analysis device and method
WO2010115167A2 (en) 2009-04-03 2010-10-07 The Regents Of The University Of California Methods and devices for sorting cells and other biological particulates
US20100273681A1 (en) 2009-04-27 2010-10-28 Wisconsin Alumni Research Foundation Combinatorial chemistry reaction cell with optical tweezers
GB0909923D0 (en) 2009-06-09 2009-07-22 Oxford Gene Tech Ip Ltd Picowell capture devices for analysing single cells or other particles
JP2011000079A (ja) 2009-06-19 2011-01-06 Univ Of Tokyo 粒子を操作する方法及びマイクロ流体装置
US20110186165A1 (en) 2009-10-05 2011-08-04 Borenstein Jeffrey T Three-dimensional microfluidic platforms and methods of use and manufacture thereof
EP2578674A4 (en) 2010-05-26 2014-04-30 Tosoh Corp DEVICE FOR FIXING BIOLOGICAL SAMPLES
CH703278B1 (fr) 2010-06-15 2016-11-15 Csem Centre Suisse D'electronique Et De Microtechnique Sa - Rech Et Développement Appareil et plateforme pour analyse multiplex.
CN101947124B (zh) 2010-06-25 2012-07-04 博奥生物有限公司 一种集成式微流控芯片装置及其使用方法
US10087408B2 (en) 2010-07-07 2018-10-02 The University Of British Columbia System and method for microfluidic cell culture
US20130115606A1 (en) 2010-07-07 2013-05-09 The University Of British Columbia System and method for microfluidic cell culture
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
US9533306B2 (en) 2010-08-02 2017-01-03 The Regents Of The University Of California Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns
US20120040843A1 (en) * 2010-08-12 2012-02-16 Dublin City University Centrifugal capture system
CN104741157B (zh) 2010-09-14 2017-04-12 加利福尼亚大学董事会 利用微流体截留涡流从异质溶液中分离细胞的装置
EP2622342A4 (en) 2010-09-29 2016-12-14 Massachusetts Inst Technology DEVICE FOR THE INVESTIGATION OF CELLULAR INTERACTIONS WITH HIGH THROUGHPUT
US9476811B2 (en) 2010-10-01 2016-10-25 The Governing Council Of The University Of Toronto Digital microfluidic devices and methods incorporating a solid phase
EP2625526B1 (en) 2010-10-04 2017-03-15 Genapsys Inc. Systems and methods for automated reusable parallel biological reactions
US8581167B2 (en) 2010-11-16 2013-11-12 Palo Alto Research Center Incorporated Optically patterned virtual electrodes and interconnects on polymer and semiconductive substrates
US9891157B2 (en) 2010-12-03 2018-02-13 Cellply S.R.L. Microanalysis of cellular function
WO2012072823A1 (en) 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Rapid screening of monoclonal antibodies
WO2012109068A2 (en) 2011-02-11 2012-08-16 Corning Incorporated Enzyme cleavable cell release polymeric surface
WO2012117588A1 (ja) * 2011-02-28 2012-09-07 独立行政法人科学技術振興機構 複数物質応答性ゲルおよびその製造方法並びにその利用
CN116179323A (zh) 2011-05-27 2023-05-30 不列颠哥伦比亚大学 用于高通量分析的微流控细胞捕获和分析设备
US9227200B2 (en) 2011-06-03 2016-01-05 The Regents Of The University Of California Microfluidic devices with flexible optically transparent electrodes
CN107315086B (zh) 2011-06-29 2019-09-10 中央研究院 使用表面涂层对生物物质的捕获、纯化和释放
CA2842359A1 (en) 2011-08-01 2013-02-07 Denovo Sciences Cell capture system and method of use
US9050593B2 (en) 2011-11-23 2015-06-09 Wisconsin Alumni Research Foundation Self-loading microfluidic device and methods of use
EP3285062B1 (en) 2012-02-29 2019-08-07 Fluidigm Corporation Methods, systems, and devices for multiple single-cell capturing and processing using microfluidics
US10626435B2 (en) 2012-03-28 2020-04-21 Northeastern University Nanofluidic device for isolating, growing, and characterizing microbial cells
KR101959447B1 (ko) 2012-04-06 2019-03-18 삼성전자주식회사 시료 중의 표적물질을 효율적으로 처리하는 방법
TWI512383B (zh) 2012-07-04 2015-12-11 Ind Tech Res Inst 光學感應式介電泳裝置
US9857333B2 (en) 2012-10-31 2018-01-02 Berkeley Lights, Inc. Pens for biological micro-objects
US9403172B2 (en) 2012-11-08 2016-08-02 Berkeley Lights, Inc. Circuit based optoelectronic tweezers
US9239328B2 (en) 2012-12-17 2016-01-19 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing semiconductor device
US9366647B2 (en) 2013-03-14 2016-06-14 Taiwan Semiconductor Manufacturing Company, Ltd. Optical detection for bio-entities
KR102402451B1 (ko) 2013-03-28 2022-05-26 더 유니버시티 오브 브리티쉬 콜롬비아 미세유동 장치 및 분비물의 다세포 검정법에서의 그의 사용 방법
KR102221894B1 (ko) 2013-10-22 2021-03-03 버클리 라잇츠, 인크. 격리 펜을 갖는 미세유체 소자 및 이를 사용한 생물학적 미세 물체를 시험하는 방법
KR102113990B1 (ko) 2013-10-22 2020-05-25 버클리 라잇츠, 인크. 생물학적 활성물 분석용 미세 유체 소자
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
SG10202105400YA (en) * 2013-10-22 2021-07-29 Berkeley Lights Inc Exporting a selected group of micro-objects from a micro-fluidic device
US20150306599A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus
US20150306598A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus
AU2015249294B2 (en) 2014-04-25 2020-02-27 Berkeley Lights, Inc. Providing DEP manipulation devices and controllable electrowetting devices in the same microfluidic apparatus
KR102369770B1 (ko) 2014-12-08 2022-03-02 버클리 라잇츠, 인크. 측방향/수직 트랜지스터 구조들을 포함하는 미세유체 디바이스 및 그 제조 및 사용 프로세스
WO2016094715A2 (en) 2014-12-10 2016-06-16 Berkeley Lights, Inc. Movement and selection of micro-objects in a microfluidic apparatus
CA2982252A1 (en) 2015-04-22 2016-10-27 Berkeley Lights, Inc. Microfluidic device for culturing biological cells and methods of use therof
KR20230042540A (ko) 2015-12-30 2023-03-28 버클리 라잇츠, 인크. 광학적으로 구동되는 대류 및 변위를 위한 미세유체 디바이스들, 키트들 및 그 방법들
JP6985289B2 (ja) 2016-04-15 2021-12-22 バークレー ライツ，インコーポレイテッド ペン内アッセイの方法、システム及びキット
KR102691104B1 (ko) 2016-05-26 2024-08-01 버클리 라잇츠, 인크. 공유 결합으로 개질된 표면들, 키트들, 및 준비 및 사용 방법들

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