JP2018538531A5 - - Google Patents

Download PDF

Info

Publication number
JP2018538531A5
JP2018538531A5 JP2018526662A JP2018526662A JP2018538531A5 JP 2018538531 A5 JP2018538531 A5 JP 2018538531A5 JP 2018526662 A JP2018526662 A JP 2018526662A JP 2018526662 A JP2018526662 A JP 2018526662A JP 2018538531 A5 JP2018538531 A5 JP 2018538531A5
Authority
JP
Japan
Prior art keywords
assay
microfluidic device
capture structure
polymer network
situ generation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018526662A
Other languages
English (en)
Japanese (ja)
Other versions
JP7083752B2 (ja
JP2018538531A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/065426 external-priority patent/WO2017100347A1/en
Publication of JP2018538531A publication Critical patent/JP2018538531A/ja
Publication of JP2018538531A5 publication Critical patent/JP2018538531A5/ja
Priority to JP2022089508A priority Critical patent/JP2022112033A/ja
Application granted granted Critical
Publication of JP7083752B2 publication Critical patent/JP7083752B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018526662A 2015-12-08 2016-12-07 マイクロ流体デバイス、そのキット、及びその使用方法 Active JP7083752B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022089508A JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562264665P 2015-12-08 2015-12-08
US62/264,665 2015-12-08
US201662333821P 2016-05-09 2016-05-09
US62/333,821 2016-05-09
US201662418625P 2016-11-07 2016-11-07
US62/418,625 2016-11-07
PCT/US2016/065426 WO2017100347A1 (en) 2015-12-08 2016-12-07 Microfluidic devices and kits and methods for use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022089508A Division JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

Publications (3)

Publication Number Publication Date
JP2018538531A JP2018538531A (ja) 2018-12-27
JP2018538531A5 true JP2018538531A5 (enExample) 2021-04-08
JP7083752B2 JP7083752B2 (ja) 2022-06-13

Family

ID=57590894

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018526662A Active JP7083752B2 (ja) 2015-12-08 2016-12-07 マイクロ流体デバイス、そのキット、及びその使用方法
JP2022089508A Pending JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022089508A Pending JP2022112033A (ja) 2015-12-08 2022-06-01 マイクロ流体デバイス、そのキット、及びその使用方法

Country Status (12)

Country Link
US (3) US10705082B2 (enExample)
EP (2) EP3387438B1 (enExample)
JP (2) JP7083752B2 (enExample)
KR (2) KR20220153685A (enExample)
CN (2) CN114878807A (enExample)
AU (1) AU2016365724B2 (enExample)
CA (1) CA3005077C (enExample)
DK (1) DK3387438T3 (enExample)
IL (2) IL297205A (enExample)
SG (1) SG11201804275TA (enExample)
TW (2) TWI758265B (enExample)
WO (1) WO2017100347A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL299366A (en) 2015-11-23 2023-02-01 Berkeley Lights Inc Structures for microfluidic isolation are produced at the place of assembly, kits and their uses
CN115184315A (zh) 2016-04-15 2022-10-14 伯克利之光生命科技公司 用于坞内测定的方法、系统和试剂盒
JP7356351B2 (ja) 2016-12-12 2023-10-04 エクセラ・バイオサイエンシーズ・インコーポレイテッド マイクロキャピラリーアレイを使用したスクリーニングのための方法およびシステム
CN110382439A (zh) 2016-12-30 2019-10-25 埃克切拉生物科学公司 多级样品回收系统
WO2018165432A1 (en) * 2017-03-08 2018-09-13 The Regents Of The University Of Michigan Functionalization of polymer scaffolds
EP3635112A2 (en) 2017-06-06 2020-04-15 Zymergen, Inc. A htp genomic engineering platform for improving fungal strains
KR102694654B1 (ko) * 2017-08-01 2024-08-12 일루미나, 인코포레이티드 뉴클레오티드 서열분석용 하이드로겔 비드
DE102017121914A1 (de) * 2017-09-21 2019-03-21 Endress+Hauser Conducta Gmbh+Co. Kg Sensorelement und Verfahren zum Herstellen eines Sensorelements
EP3721209B1 (en) * 2017-10-15 2024-02-07 Berkeley Lights, Inc. Methods for in-pen assays
TWI652658B (zh) 2017-12-12 2019-03-01 奇景光電股份有限公司 晶片以及使用其的電子裝置
WO2019133874A1 (en) * 2017-12-31 2019-07-04 Berkeley Lights, Inc. General functional assay
EP3752634B8 (en) 2018-02-13 2023-10-11 Illumina, Inc. Dna sequencing using hydrogel beads
KR102657606B1 (ko) 2018-04-20 2024-04-15 일루미나, 인코포레이티드 단일 세포를 캡슐화하는 방법, 캡슐화된 세포 및 이의 용도
CN112166180A (zh) 2018-06-06 2021-01-01 齐默尔根公司 操纵涉及信号转导的基因以控制发酵和生产期间的真菌形态
US20210162413A1 (en) * 2018-06-18 2021-06-03 Hewlett-Packard Development Company, L.P. Microfluidic immunoassays
JP2022512637A (ja) * 2018-10-11 2022-02-07 バークレー ライツ，インコーポレイテッド 最適化タンパク質生成の同定のためのシステム及び方法並びにそのためのキット
CN111036315B (zh) * 2018-10-15 2021-09-21 京东方科技集团股份有限公司 一种微量样品的生成方法及生成芯片
MY202795A (en) 2018-10-26 2024-05-22 Illumina Inc Modulating polymer beads for dna processing
CA3118957A1 (en) * 2018-11-01 2020-05-07 Berkeley Lights, Inc. Methods for assaying biological cells in a microfluidic environment
EP3890876B1 (en) 2018-12-06 2024-05-01 Xcella Biosciences, Inc. Lateral loading of microcapillary arrays
JP7231923B2 (ja) * 2019-01-15 2023-03-02 国立大学法人東京工業大学 複合体の検出方法、並びにそれに用いる担体及び検出キット
US20220146502A1 (en) * 2019-02-01 2022-05-12 Sentilus Holdco, Llc High-sensitivity assay
CN110054146B (zh) * 2019-03-18 2021-08-24 北京航空航天大学 一种周期性v型微柱结构复合膜及其制备方法与应用
CN114126762B (zh) * 2019-04-30 2023-01-03 伯克利之光生命科技公司 用于包封和测定细胞的方法
US11668676B2 (en) * 2019-05-30 2023-06-06 The Regents Of The University Of California Microfluidic acoustic devices and methods
WO2021067401A1 (en) * 2019-09-30 2021-04-08 University Of Florida Research Foundation, Incorporated Use of ganglioside 2 and 3 for circulating sarcoma cell detection
AU2020385015A1 (en) 2019-11-17 2022-06-09 Berkeley Lights, Inc. Systems and methods for analyses of biological samples
CN111046607B (zh) * 2019-12-12 2025-05-13 浙江清华柔性电子技术研究院 柔性微流体器件设计方法及柔性微流体器件
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
WO2022109075A1 (en) * 2020-11-17 2022-05-27 Xbiologix, Inc. Configurable substrate of a fluidic device
US12377415B2 (en) 2020-12-30 2025-08-05 The Trustees Of The University Of Pennsylvania Photoactivated selective release (PHASR) of droplets from microwell arrays
WO2022216778A1 (en) * 2021-04-06 2022-10-13 Berkeley Lights, Inc. Methods of microfluidic assay and bioproduction from non-mammalian cells and kits therefor
EP4444910A4 (en) * 2021-12-10 2025-11-05 Bio Rad Laboratories Inc Compositions, processes and systems for the treatment of samples with functionalized particles of adjustable morphology
EP4469207A4 (en) * 2022-01-25 2025-12-31 Bruker Cellular Analysis Inc METHODS FOR DOSING MICRO-OBJECTS IN A MICROFLUID DEVICE
EP4619551A2 (en) * 2022-11-17 2025-09-24 Bruker Cellular Analysis, Inc. Methods of evaluating virus-producing cells
WO2025068547A1 (en) * 2023-09-28 2025-04-03 Zhen Zhang A microfluidic device, a microfluidic system and a method for the capture and controllable release of single biological cells

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387707B1 (en) 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
EP2290364A1 (en) 1996-04-25 2011-03-02 BioArray Solutions Ltd. Light-controlled electrokinetic assembly of particles near surfaces
WO2000046595A1 (en) 1999-02-03 2000-08-10 Aclara Biosciences, Inc. Multichannel control in microfluidics
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US6942776B2 (en) 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
ATE215673T1 (de) 1999-06-28 2002-04-15 California Inst Of Techn Elastomerische mikropumpen- und mikroventilsysteme
KR100677860B1 (ko) 1999-07-23 2007-02-05 보드 오브 트러스티스 오브 유니버스티 오브 일리노이즈 미세하게 제조되는 장치 및 그의 제조방법
US6794196B2 (en) 1999-12-20 2004-09-21 The Penn State Research Foundation Deposited thin films and their use in detection, attachment and bio-medical applications
US20030007894A1 (en) 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
EP1343973B2 (en) * 2000-11-16 2020-09-16 California Institute Of Technology Apparatus and methods for conducting assays and high throughput screening
ITTO20010411A1 (it) 2001-05-02 2002-11-02 Silicon Biosystems S R L Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti.
US20030175947A1 (en) 2001-11-05 2003-09-18 Liu Robin Hui Enhanced mixing in microfluidic devices
US7312085B2 (en) 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
US7824854B2 (en) * 2002-05-07 2010-11-02 Japan Science And Technology Agency Method or apparatus for recovering micromaterial
US6958132B2 (en) 2002-05-31 2005-10-25 The Regents Of The University Of California Systems and methods for optical actuation of microfluidics based on opto-electrowetting
DE10224352A1 (de) * 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
US7790443B2 (en) 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
CN100537219C (zh) * 2002-12-30 2009-09-09 加州大学评议会 检测和分析病原体的方法和设备
AU2003303594A1 (en) 2002-12-30 2004-07-29 The Regents Of The University Of California Methods and apparatus for pathogen detection and analysis
WO2004065618A2 (en) 2003-01-16 2004-08-05 Thermogenic Imaging Methods and devices for monitoring cellular metabolism in microfluidic cell-retaining chambers
EP1615721B1 (en) 2003-04-03 2014-06-18 Fluidigm Corporation Microfluidic devices and methods of using same
US20060240548A1 (en) 2003-06-26 2006-10-26 Mordechai Deutsch Materials for constructing cell-chips, cell-chip covers, cell-chips coats, processed cell-chips and uses thereof
WO2005007796A2 (en) 2003-07-21 2005-01-27 Molecular Cytomics Ltd. Improved multiwell plate
US20050164402A1 (en) 2003-07-14 2005-07-28 Belisle Christopher M. Sample presentation device
US20060194306A1 (en) * 2003-08-25 2006-08-31 Herr Amy E System for gel electrophoretic immunoassay
JP4328168B2 (ja) 2003-10-02 2009-09-09 ソニー株式会社 毛細管現象を利用する物質間の相互作用検出部と該検出部を用いる方法及びバイオアッセイ用基板
WO2005040403A1 (en) 2003-10-29 2005-05-06 Agency For Science, Technology And Research Method for detecting analytes by means of an analyte/polymeric activator bilayer arrangement
WO2005072399A2 (en) 2004-01-29 2005-08-11 Massachusetts Institute Of Technology Microscale sorting cytometer
WO2005080606A1 (en) 2004-02-18 2005-09-01 Xiaochuan Zhou Fluidic devices and methods for multiplex chemical and biochemical reactions
US20050221473A1 (en) 2004-03-30 2005-10-06 Intel Corporation Sensor array integrated circuits
EP1735428A4 (en) 2004-04-12 2010-11-10 Univ California OPTOELECTRONIC TWEEZERS FOR MANIPULATING MICROPARTICLES AND CELLS
US7935479B2 (en) 2004-07-19 2011-05-03 Cell Biosciences, Inc. Methods and devices for analyte detection
US7258990B2 (en) * 2004-08-19 2007-08-21 Biocept, Inc. Alleviation of non-specific binding in microarray assays
US20080014575A1 (en) 2004-10-25 2008-01-17 University Of Washington Rapid Microfluidic Assay for Quantitative Measurement of Interactions Among One or More Analytes
US20060091015A1 (en) 2004-11-01 2006-05-04 Applera Corporation Surface modification for non-specific adsorption of biological material
US20060237080A1 (en) * 2005-02-15 2006-10-26 Sangyong Jon Patterned surfaces and polymeric microstructures within robust microfluidic channels
JP2006308332A (ja) 2005-04-26 2006-11-09 Moritex Corp 固定反応物質と液体反応物質との反応用フローセル及び反応装置並びに反応装置の運転方法
TWI265864B (en) 2005-05-20 2006-11-11 Univ Nat Cheng Kung Hydrophilic surface structure of non-hydrophilic substrate and fabricating method for the same
US9260688B2 (en) 2005-07-07 2016-02-16 The Regents Of The University Of California Methods and apparatus for cell culture array
CA2616504A1 (en) 2005-08-19 2007-03-01 The Regents Of The University Of California Microfluidic methods for diagnostics and cellular analysis
US20070095667A1 (en) 2005-10-27 2007-05-03 Applera Corporation Optoelectronic Separation of Biomolecules
TW200734641A (en) 2005-12-26 2007-09-16 Inst Of Microchemical Technology Microchip for immunoassay, kit for immunoassay and immunoassay method
US20090011486A1 (en) * 2006-01-12 2009-01-08 Massachusetts Institute Of Technology Biodegradable Elastomers
WO2007092713A2 (en) 2006-02-02 2007-08-16 Trustees Of The University Of Pennsylvania Microfluidic system and method for analysis of gene expression in cell-containing samples and detection of disease
US8124015B2 (en) 2006-02-03 2012-02-28 Institute For Systems Biology Multiplexed, microfluidic molecular assay device and assay method
AU2007212306A1 (en) 2006-02-07 2007-08-16 Wafergen, Inc. Temperature-regulated culture plates
US8980198B2 (en) 2006-04-18 2015-03-17 Advanced Liquid Logic, Inc. Filler fluids for droplet operations
US20150107995A1 (en) 2006-04-18 2015-04-23 Advanced Liquid Logic, Inc. Droplet Actuator Devices and Methods for Manipulating Beads
US9512278B2 (en) * 2006-10-25 2016-12-06 Massachusetts Institute Of Technology Lock-release polymerization
US7790631B2 (en) 2006-11-21 2010-09-07 Intel Corporation Selective deposition of a dielectric on a self-assembled monolayer-adsorbed metal
US20080153134A1 (en) 2006-12-22 2008-06-26 Willy Wiyatno Methods and apparatus for generating hydrophilic patterning of high density microplates using an amphiphilic polymer
US20100285490A1 (en) 2006-12-29 2010-11-11 Invitrogen Corporation Detection apparatus
WO2008089493A2 (en) 2007-01-19 2008-07-24 Fluidigm Corporation High precision microfluidic devices and methods
US8685344B2 (en) 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
WO2008119066A1 (en) 2007-03-28 2008-10-02 The Regents Of The University Of California Single-sided lateral-field and phototransistor-based optoelectronic tweezers
WO2008131035A2 (en) * 2007-04-16 2008-10-30 Cellpoint Diagnotics, Inc. Methods for diagnosing, prognosing, or theranosing a condition using rare cells
WO2008147530A1 (en) 2007-05-24 2008-12-04 The Regents Of The University Of California Integrated fluidics devices with magnetic sorting
US8961877B2 (en) 2007-08-09 2015-02-24 Massachusetts Institute Of Technology High-throughput, whole-animal screening system
WO2009061392A1 (en) 2007-11-05 2009-05-14 President And Fellows Of Harvard College Forming gel structures using microfluidic channels
CN101910415B (zh) 2007-11-07 2015-02-25 不列颠哥伦比亚大学 微流体装置及其使用方法
WO2009130694A2 (en) 2008-04-21 2009-10-29 Cell Kinetics Ltd. Flat cell carriers with cell traps
CN101275114A (zh) 2008-04-22 2008-10-01 北京大学 一种微流细胞培养阵列及其应用
KR100991752B1 (ko) 2008-07-15 2010-11-03 한국과학기술원 단일 평면 광전자 소자를 이용한 미세입자 구동장치 및구동방법
GB2464300A (en) 2008-10-10 2010-04-14 Univ Dublin City Microfluidic multiplexed cellular and molecular analysis device and method
WO2010115167A2 (en) 2009-04-03 2010-10-07 The Regents Of The University Of California Methods and devices for sorting cells and other biological particulates
US20100273681A1 (en) 2009-04-27 2010-10-28 Wisconsin Alumni Research Foundation Combinatorial chemistry reaction cell with optical tweezers
GB0909923D0 (en) 2009-06-09 2009-07-22 Oxford Gene Tech Ip Ltd Picowell capture devices for analysing single cells or other particles
JP2011000079A (ja) 2009-06-19 2011-01-06 Univ Of Tokyo 粒子を操作する方法及びマイクロ流体装置
US20110186165A1 (en) 2009-10-05 2011-08-04 Borenstein Jeffrey T Three-dimensional microfluidic platforms and methods of use and manufacture thereof
JPWO2011149032A1 (ja) 2010-05-26 2013-07-25 東ソー株式会社 生体試料固定装置
CH703278B1 (fr) 2010-06-15 2016-11-15 Csem Centre Suisse D'electronique Et De Microtechnique Sa - Rech Et Développement Appareil et plateforme pour analyse multiplex.
CN101947124B (zh) 2010-06-25 2012-07-04 博奥生物有限公司 一种集成式微流控芯片装置及其使用方法
US20130115606A1 (en) 2010-07-07 2013-05-09 The University Of British Columbia System and method for microfluidic cell culture
US10087408B2 (en) 2010-07-07 2018-10-02 The University Of British Columbia System and method for microfluidic cell culture
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
US9533306B2 (en) 2010-08-02 2017-01-03 The Regents Of The University Of California Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns
US20120040843A1 (en) * 2010-08-12 2012-02-16 Dublin City University Centrifugal capture system
WO2012037030A2 (en) 2010-09-14 2012-03-22 The Regents Of The University Of California Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices
US9261496B2 (en) 2010-09-29 2016-02-16 Massachusetts Institute Of Technology Device for high throughput investigations of multi-cellular interactions
US9476811B2 (en) 2010-10-01 2016-10-25 The Governing Council Of The University Of Toronto Digital microfluidic devices and methods incorporating a solid phase
NZ610129A (en) 2010-10-04 2014-08-29 Genapsys Inc Systems and methods for automated reusable parallel biological reactions
US8581167B2 (en) 2010-11-16 2013-11-12 Palo Alto Research Center Incorporated Optically patterned virtual electrodes and interconnects on polymer and semiconductive substrates
US10571475B2 (en) 2010-12-03 2020-02-25 Cellply S.R.L. Rapid screening of monoclonal antibodies
EP3035031B1 (en) 2010-12-03 2022-06-01 Cellply S.R.L. Microanalysis of cellular function
WO2012109068A2 (en) 2011-02-11 2012-08-16 Corning Incorporated Enzyme cleavable cell release polymeric surface
JP5093633B2 (ja) * 2011-02-28 2012-12-12 独立行政法人科学技術振興機構 複数物質応答性ゲルおよびその製造方法並びにその利用
US9902990B2 (en) 2011-05-27 2018-02-27 The University Of British Columbia Microfluidic cell trap and assay apparatus for high-throughput analysis
US9227200B2 (en) 2011-06-03 2016-01-05 The Regents Of The University Of California Microfluidic devices with flexible optically transparent electrodes
CN107315086B (zh) * 2011-06-29 2019-09-10 中央研究院 使用表面涂层对生物物质的捕获、纯化和释放
WO2013019491A1 (en) 2011-08-01 2013-02-07 Denovo Sciences Cell capture system and method of use
US9050593B2 (en) 2011-11-23 2015-06-09 Wisconsin Alumni Research Foundation Self-loading microfluidic device and methods of use
US9506845B2 (en) 2012-02-29 2016-11-29 Fluidigm Corporation Methods, systems and devices for multiple single-cell capturing and processing using microfluidics
US10626435B2 (en) 2012-03-28 2020-04-21 Northeastern University Nanofluidic device for isolating, growing, and characterizing microbial cells
KR101959447B1 (ko) 2012-04-06 2019-03-18 삼성전자주식회사 시료 중의 표적물질을 효율적으로 처리하는 방법
US9144806B2 (en) 2012-07-04 2015-09-29 Industrial Technology Research Institute Optically-induced dielectrophoresis device
US9857333B2 (en) 2012-10-31 2018-01-02 Berkeley Lights, Inc. Pens for biological micro-objects
US9403172B2 (en) 2012-11-08 2016-08-02 Berkeley Lights, Inc. Circuit based optoelectronic tweezers
US9366647B2 (en) 2013-03-14 2016-06-14 Taiwan Semiconductor Manufacturing Company, Ltd. Optical detection for bio-entities
US9239328B2 (en) 2012-12-17 2016-01-19 Taiwan Semiconductor Manufacturing Company, Ltd. Systems and methods for an integrated bio-entity manipulation and processing semiconductor device
NZ711723A (en) 2013-03-28 2021-12-24 Univ British Columbia Microfluidic devices and methods for use thereof in multicellular assays of secretion
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
AU2014340098B2 (en) 2013-10-22 2020-05-28 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
EP3473699B1 (en) * 2013-10-22 2020-08-26 Berkeley Lights, Inc. Exporting a selected group of micro-objects from a micro-fluidic device
KR102221894B1 (ko) * 2013-10-22 2021-03-03 버클리 라잇츠, 인크. 격리 펜을 갖는 미세유체 소자 및 이를 사용한 생물학적 미세 물체를 시험하는 방법
US20150306598A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus
US20150306599A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus
KR102232094B1 (ko) 2014-04-25 2021-03-25 버클리 라잇츠, 인크. 동일한 미세유체 장치에의 dep 처리 디바이스들 및 제어가능 전기습윤 디바이스들의 제공
TWI721545B (zh) 2014-12-08 2021-03-11 美商柏克萊燈光有限公司 側向式/垂直式電晶體結構及其製造與使用方法
WO2016094715A2 (en) 2014-12-10 2016-06-16 Berkeley Lights, Inc. Movement and selection of micro-objects in a microfluidic apparatus
KR102384741B1 (ko) 2015-04-22 2022-04-07 버클리 라잇츠, 인크. 미세유체 세포 배양
AU2016381833C1 (en) 2015-12-30 2022-10-06 Berkeley Lights, Inc. Microfluidic devices for optically-driven convection and displacement, kits and methods thereof
CN115184315A (zh) 2016-04-15 2022-10-14 伯克利之光生命科技公司 用于坞内测定的方法、系统和试剂盒
WO2017205830A1 (en) 2016-05-26 2017-11-30 Berkeley Lights, Inc. Covalently modified surfaces, kits, and methods of preparation and use

Similar Documents

Publication Publication Date Title
JP2018538531A5 (enExample)
Choi et al. Sensitive biomolecule detection in lateral flow assay with a portable temperature–humidity control device
JP6957517B2 (ja) 集積型マイクロ流体チップおよび使用方法
JP2022547801A (ja) 液滴操作のための方法およびシステム
CN107884566B (zh) 可规模化生物元素分析
Jalali et al. A hierarchical 3D nanostructured microfluidic device for sensitive detection of pathogenic bacteria
Chen et al. Surface‐micromachined microfiltration membranes for efficient isolation and functional immunophenotyping of subpopulations of immune cells
US20030138941A1 (en) Sample preparation integrated chip
US9304128B1 (en) Toxin activity assays, devices, methods and systems therefor
JP2013539867A5 (enExample)
JP2017514686A (ja) マルチインデックス検出マイクロ流体チップおよび使用方法
US20210016283A1 (en) Ultrahigh throughput protein discovery
WO2003035909A2 (en) A method for detecting disease using a fluidic device
JP2005521425A (ja) 微小流体粒子分析システム
EP1461606A4 (en) MICROFLUIDIC DEVICE AND SURFACE DECORATION PROCESS FOR SOLID PHASE AFFINITY BINDING ASSAYS
WO2008048300A3 (en) Pathogen detection biosensor
CN109715646A (zh) 用于样品分析的装置和方法
EP3058372B1 (en) Detection units and methods for detecting a target analyte
CN108290158A (zh) 测定板及其用途
WO2014107698A1 (en) System and method for picoliter volume microfluidic diagnotics
ATE466108T1 (de) Optoelektronisches detektionssystem
AU2015307229A1 (en) In-field dna extraction, detection and authentication methods and systems therefor
Tavakoli et al. Paper and paper hybrid microfluidic devices for point‐of‐care detection of infectious diseases
DE212016000125U1 (de) Oligonukleotid vermittelte Analyse von Biomarkern
TW202242128A (zh) 用於檢測樣品分析物之結構及方法