JP2018530529A5 - - Google Patents

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JP2018530529A5
JP2018530529A5 JP2018511488A JP2018511488A JP2018530529A5 JP 2018530529 A5 JP2018530529 A5 JP 2018530529A5 JP 2018511488 A JP2018511488 A JP 2018511488A JP 2018511488 A JP2018511488 A JP 2018511488A JP 2018530529 A5 JP2018530529 A5 JP 2018530529A5
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nucleotides
nucleotide
rnai agent
double
pharmaceutical composition
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JP2018511488A
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JP7028764B2 (ja
JP2018530529A (ja
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Priority to JP2021195074A priority Critical patent/JP2022033857A/ja
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Priority to JP2023154150A priority patent/JP2023166601A/ja
Priority to JP2025040860A priority patent/JP2025106281A/ja
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JP2018511488A 2015-09-02 2016-08-22 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法 Active JP7028764B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2021195074A JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2023154150A JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2025040860A JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562213224P 2015-09-02 2015-09-02
US62/213,224 2015-09-02
PCT/US2016/047946 WO2017040078A1 (en) 2015-09-02 2016-08-22 PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

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JP2021195074A Division JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法

Publications (3)

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JP2018530529A JP2018530529A (ja) 2018-10-18
JP2018530529A5 true JP2018530529A5 (enExample) 2019-09-26
JP7028764B2 JP7028764B2 (ja) 2022-03-02

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JP2018511488A Active JP7028764B2 (ja) 2015-09-02 2016-08-22 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2021195074A Pending JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2023154150A Pending JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2025040860A Pending JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法

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JP2021195074A Pending JP2022033857A (ja) 2015-09-02 2021-12-01 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2023154150A Pending JP2023166601A (ja) 2015-09-02 2023-09-21 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法
JP2025040860A Pending JP2025106281A (ja) 2015-09-02 2025-03-14 プログラム細胞死1リガンド1(PD-L1)iRNA組成物およびその使用方法

Country Status (12)

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US (2) US10889813B2 (enExample)
EP (2) EP4393495A3 (enExample)
JP (4) JP7028764B2 (enExample)
KR (2) KR20250145703A (enExample)
CN (2) CN114525280A (enExample)
AU (1) AU2016315584B2 (enExample)
CA (1) CA2996873A1 (enExample)
EA (1) EA201890619A1 (enExample)
PE (1) PE20181131A1 (enExample)
SA (1) SA518391045B1 (enExample)
SG (1) SG10202007937SA (enExample)
WO (1) WO2017040078A1 (enExample)

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WO2021061437A1 (en) * 2019-09-12 2021-04-01 Sirnaomics, Inc. CO-DELIVERY OF TGF-β SIRNA AND PDL1 SIRNA TO TREAT CANCER
JP7676377B2 (ja) 2019-10-22 2025-05-14 アルナイラム ファーマシューティカルズ, インコーポレイテッド 補体成分C3 iRNA組成物およびその使用方法
US20240182900A1 (en) * 2019-11-07 2024-06-06 Yale University Microrna blockade for the treatment of disease
JP2023515218A (ja) * 2020-02-28 2023-04-12 アリゴス セラピューティクス インコーポレイテッド Pd-l1を標的とするための方法及び組成物
CN112180005B (zh) * 2020-09-01 2022-10-04 上海市疾病预防控制中心 一种预测鉴定生物样本中酰基肉碱的方法及其应用
CN115216474B (zh) * 2021-04-15 2025-09-30 武汉大学 促进pd-l1外显子3跳跃的反义寡核苷酸及其应用
EP4423273A1 (en) 2021-10-29 2024-09-04 Alnylam Pharmaceuticals, Inc. Complement factor b (cfb) irna compositions and methods of use thereof
KR20230128690A (ko) * 2022-02-28 2023-09-05 주식회사 시선테라퓨틱스 핵산 복합체를 포함하는 폐암 예방 또는 치료용 조성물
WO2023233290A1 (en) * 2022-05-31 2023-12-07 Janssen Sciences Ireland Unlimited Company Rnai agents targeting pd-l1
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WO2024169306A1 (zh) * 2023-02-17 2024-08-22 苏州时安生物技术有限公司 一种用于抑制细胞程序性死亡-配体1基因表达的siRNA、其缀合物和药物组合物及用途
TW202504619A (zh) * 2023-07-20 2025-02-01 大陸商上海舶望製藥有限公司 用於抑制pd-l1表達的組合物和方法
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