JP2018527005A5 - - Google Patents

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JP2018527005A5
JP2018527005A5 JP2018514376A JP2018514376A JP2018527005A5 JP 2018527005 A5 JP2018527005 A5 JP 2018527005A5 JP 2018514376 A JP2018514376 A JP 2018514376A JP 2018514376 A JP2018514376 A JP 2018514376A JP 2018527005 A5 JP2018527005 A5 JP 2018527005A5
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Japan
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human mammal
eif2s3y
uty
ddx3y
expression
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JP2018514376A
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Japanese (ja)
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JP2018527005A (ja
JP6868615B2 (ja
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Priority claimed from PCT/US2016/052345 external-priority patent/WO2017049240A1/en
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JP2018514376A 2015-09-17 2016-09-16 繁殖可能なxy雌マウスを生成するための多能性細胞の選択 Active JP6868615B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562219927P 2015-09-17 2015-09-17
US62/219,927 2015-09-17
PCT/US2016/052345 WO2017049240A1 (en) 2015-09-17 2016-09-16 Selection of pluripotent cells for production of fertile xy female mice

Publications (3)

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JP2018527005A JP2018527005A (ja) 2018-09-20
JP2018527005A5 true JP2018527005A5 (enExample) 2019-10-10
JP6868615B2 JP6868615B2 (ja) 2021-05-12

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JP2018514376A Active JP6868615B2 (ja) 2015-09-17 2016-09-16 繁殖可能なxy雌マウスを生成するための多能性細胞の選択

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US (2) US10893666B2 (enExample)
EP (1) EP3349573B1 (enExample)
JP (1) JP6868615B2 (enExample)
KR (1) KR102382458B1 (enExample)
CN (1) CN108697068B (enExample)
AU (1) AU2016324305B2 (enExample)
CA (1) CA2998642C (enExample)
IL (1) IL257982B2 (enExample)
MX (1) MX388475B (enExample)
RU (1) RU2729407C1 (enExample)
SG (1) SG10201913789VA (enExample)
WO (1) WO2017049240A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10893666B2 (en) 2015-09-17 2021-01-19 Regeneron Pharmaceuticals, Inc. Production of fertile XY female animals by silencing of genes on the Y chromosome
CN108998540A (zh) * 2018-08-18 2018-12-14 兰州大学 绵羊eif2s3y基因的单核苷酸多态性标记及其检测引物、试剂盒、方法及应用
CN110656167A (zh) * 2019-09-27 2020-01-07 中国科学院苏州生物医学工程技术研究所 用于y染色体微缺失检测的引物组、试剂盒及基于数字pcr的检测方法
CN111321232B (zh) * 2020-03-18 2022-08-16 西北农林科技大学 一种快速检测肉牛eif4a2基因拷贝数变异的方法及其应用
CN113558012A (zh) * 2021-08-05 2021-10-29 陈米米 一种哺乳动物繁育雌性多胎的方法
CN114015705A (zh) * 2021-11-28 2022-02-08 华中科技大学同济医学院附属协和医院 一种小鼠体外受精繁育性别选择方法
CN115251007B (zh) * 2022-09-02 2024-01-26 山西医科大学 一种新品系裸大鼠、其培育方法及应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0907722A1 (en) 1996-04-29 1999-04-14 Leuven Research & Development V.Z.W. Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits
EP1067141A1 (en) * 1999-06-11 2001-01-10 Rijksuniversiteit te Leiden A male-specific protein homologue involved in histocompatibility
IL149201A0 (en) * 1999-11-02 2002-11-10 Univ Massachusetts Use of haploid genomes for genetic diagnosis, modification and multiplication
CA2394812A1 (en) 1999-12-20 2001-06-28 Anthony C.F. Perry A method to produce cloned embryos and adults from cultured cells
JPWO2003071869A1 (ja) 2002-02-27 2005-06-16 恭光 長尾 生殖系列キメラ動物の作製方法
ATE306810T1 (de) 2002-03-05 2005-11-15 Artemis Pharmaceuticals Gmbh Durch inzucht erzeugte von embryonalen stammzellen abgeleitete mäuse
EP1516924A1 (en) 2003-09-17 2005-03-23 Fundacion IVI para el Estudio de la reproduccion Humana (FIVIER) Generation of human embryonic stem cells from triploid zygotes
KR101178786B1 (ko) 2004-03-23 2012-09-07 다이이찌 산쿄 가부시키가이샤 다능성 줄기세포의 증식 방법
WO2006044962A1 (en) 2004-10-19 2006-04-27 Regeneron Pharmaceuticals, Inc. Method for generating an animal homozygous for a genetic modification
CN101506354B (zh) 2006-08-09 2014-05-07 瓦内瓦公司 用胚胎干细胞制备转基因禽类的方法
GB0623635D0 (en) 2006-11-27 2007-01-03 Stem Cell Sciences Uk Ltd Pluripotent cell growth media
WO2009037337A1 (en) 2007-09-20 2009-03-26 Novartis Ag Robust and tissue independent gender-specific transcript markers for molecular gender determination
CA2751596A1 (en) * 2009-02-08 2010-08-12 The University Of Melbourne Sex-determination and methods of specifying same
AU2010306377B2 (en) 2009-10-13 2015-01-22 Stemcell Technologies Canada Inc. Manipulation of osmolality for differentiating stem cells
CN104711218B (zh) 2010-06-11 2018-09-25 瑞泽恩制药公司 由xy es细胞制备能育的xy雌性动物
WO2012022634A1 (en) * 2010-08-16 2012-02-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Classification, diagnosis and prognosis of multiple myeloma
PT3161128T (pt) * 2014-06-26 2018-11-21 Regeneron Pharma Métodos e composições para modificações genéticas alvejadas e métodos de utilização
SG11201702309RA (en) 2014-10-15 2017-04-27 Regeneron Pharma Methods and compositions for generating or maintaining pluripotent cells
US10893666B2 (en) 2015-09-17 2021-01-19 Regeneron Pharmaceuticals, Inc. Production of fertile XY female animals by silencing of genes on the Y chromosome

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