MXPA02004333A - Uso de genomas haploides para diagnostico, modificacion y multiplicacion genetica. - Google Patents

Uso de genomas haploides para diagnostico, modificacion y multiplicacion genetica.

Info

Publication number
MXPA02004333A
MXPA02004333A MXPA02004333A MXPA02004333A MXPA02004333A MX PA02004333 A MXPA02004333 A MX PA02004333A MX PA02004333 A MXPA02004333 A MX PA02004333A MX PA02004333 A MXPA02004333 A MX PA02004333A MX PA02004333 A MXPA02004333 A MX PA02004333A
Authority
MX
Mexico
Prior art keywords
haploid genomes
modification
cells
multiplication
units
Prior art date
Application number
MXPA02004333A
Other languages
English (en)
Inventor
M Robl James
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Publication of MXPA02004333A publication Critical patent/MXPA02004333A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se describen los metodos para propagar genomas haploides de origen masculino o femenino y la seleccion genetica y la modificacion de los mismos. Estos genomas haploides pueden ser utilizados para producir embriones haploides, y las lineas similares a la linea embrionaria, y celulas diferenciadas. Tambien, estos genomas haploides y las celulas que los contienen, pueden ser utilizados como donadores de transferencia nuclear para producir unidades de transferencia nuclear diploides. Estas unidades NT diploides, por ejemplo, unidades NT humanas, pueden ser utilizadas para obtener celulas pluripotenciales y celulas y tejidos diferenciados.
MXPA02004333A 1999-11-02 2000-11-02 Uso de genomas haploides para diagnostico, modificacion y multiplicacion genetica. MXPA02004333A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16308699P 1999-11-02 1999-11-02
PCT/US2000/030202 WO2001032015A1 (en) 1999-11-02 2000-11-02 Use of haploid genomes for genetic diagnosis, modification and multiplication

Publications (1)

Publication Number Publication Date
MXPA02004333A true MXPA02004333A (es) 2004-04-21

Family

ID=22588424

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02004333A MXPA02004333A (es) 1999-11-02 2000-11-02 Uso de genomas haploides para diagnostico, modificacion y multiplicacion genetica.

Country Status (10)

Country Link
US (3) US20040146865A1 (es)
EP (1) EP1227719A4 (es)
JP (1) JP2003512848A (es)
CN (1) CN1387401A (es)
AU (1) AU1581001A (es)
BR (1) BR0015264A (es)
CA (1) CA2388510A1 (es)
IL (1) IL149201A0 (es)
MX (1) MXPA02004333A (es)
WO (1) WO2001032015A1 (es)

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US7253334B2 (en) * 2000-12-22 2007-08-07 Aurox, Llc Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
GB0025088D0 (en) * 2000-10-13 2000-11-29 Univ Edinburgh Stem cells
CN100422315C (zh) * 2000-11-30 2008-10-01 斯坦姆荣公司 分离的纯合干细胞,由其衍生的分化细胞,以及制备和使用上述细胞的材料和方法
US7491534B2 (en) * 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
IL156746A0 (en) * 2001-01-02 2004-02-08 Stemron Inc A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom and materials and method using same
CA2505598A1 (en) * 2002-05-24 2003-12-04 Advanced Cell Technology, Inc. A bank of stem cells for transplantation
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
WO2006041910A2 (en) * 2004-10-05 2006-04-20 Trustees Of The University Of Pennsylvania Stem cells derived from uniparental embryos and methods of use thereof
US20080215353A1 (en) * 2006-08-31 2008-09-04 Akin James W Method of Frozen Donor Egg Banking
US7718418B2 (en) 2007-01-08 2010-05-18 The Invention Science Fund I, Llc Systems for genome selection
US8521440B2 (en) * 2007-01-08 2013-08-27 The Invention Science Fund I, Llc Systems for genome selection
US7947457B2 (en) * 2007-01-08 2011-05-24 The Invention Science Fund I, Llc Systems for genome selection
US8012740B2 (en) * 2007-01-08 2011-09-06 The Invention Science Fund I, Llc Systems for genome selection
US7947455B2 (en) * 2007-01-08 2011-05-24 The Invention Science Fund I, Llc System for genome selection
US7648823B2 (en) * 2007-01-08 2010-01-19 Searete Llc Systems for genome selection
US7709245B2 (en) 2007-01-08 2010-05-04 The Invention Science Fund I, Llc Systems for genome selection
US7709244B2 (en) * 2007-01-08 2010-05-04 The Invention Science Fund I, Llc Systems for genome selection
US7985578B2 (en) 2007-01-08 2011-07-26 The Invention Science Fund I, Llc Systems for genome selection
US7713728B2 (en) * 2007-01-08 2010-05-11 The Invention Sciencefund I, Llc Systems for genome selection
US8003371B2 (en) 2007-01-08 2011-08-23 The Invention Science Fund I, Llc Systems for genome selection
US20080167851A1 (en) * 2007-01-08 2008-07-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for genome selection
US20090111184A1 (en) * 2007-10-24 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Chromosome selection
US20090111764A1 (en) * 2007-10-25 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Mitochondrial selection
US20090111185A1 (en) * 2007-10-26 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Female genome selection
WO2012071393A2 (en) * 2010-11-23 2012-05-31 The New York Stem Cell Foundation Method for producing pluripotent stem cells
DK2681310T4 (da) * 2011-03-02 2020-04-20 Anton Wutz Haploide embryoniske pattedyrestamceller
CN102533970A (zh) * 2011-11-14 2012-07-04 江苏迈健生物科技发展有限公司 一种反转录pcr分析ivf单个植入前胚胎的基因表达方法
EP2599859A1 (en) 2011-11-30 2013-06-05 IMBA-Institut für Molekulare Biotechnologie GmbH Haploid cells
DK3274710T3 (da) 2015-03-23 2021-09-06 Astellas Inst For Regenerative Medicine Forbedrede assays til måling af styrken af humane retinale pigmentepitel (rpe)-celler og fotoreceptorprogenitorer
CA2998642C (en) 2015-09-17 2023-09-12 Regeneron Pharmaceuticals, Inc. Selection of pluripotent cells for production of fertile xy female mice
CN109689894A (zh) * 2016-06-19 2019-04-26 耶路撒冷希伯来大学伊萨姆研发有限公司 在人单倍体细胞中筛选化学疗法抗性
EP3421593A1 (en) * 2017-06-30 2019-01-02 Centre National De La Recherche Scientifique Method for obtaining haploid cells
EP3927813A4 (en) * 2019-02-20 2022-11-09 The Semex Alliance USE OF HAPLOID EMBRYONIC CELLS TO GENERATE PROGENY WITH PREDETERMINED GENOMES
CN112375829B (zh) * 2020-11-25 2022-07-05 苏州赛美科基因科技有限公司 使用家系wes数据识别upd的方法、装置及电子设备

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480772A (en) * 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5749169A (en) * 1995-06-07 1998-05-12 Pioneer Hi-Bred International, Inc. Use of the indeterminate gametophyte gene for maize improvement
US5932418A (en) * 1996-04-08 1999-08-03 Naiad Systems, Inc. Fish embryo screening test for genotoxic agents using three different developmental life stages
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
JP2003514516A (ja) * 1999-10-28 2003-04-22 ユニバーシティ オブ マサチューセッツ 多能性細胞と細胞株の雌性発生的または雄性発生的産生および分化した細胞と組織を産生するためのその使用

Also Published As

Publication number Publication date
JP2003512848A (ja) 2003-04-08
BR0015264A (pt) 2002-10-15
WO2001032015A1 (en) 2001-05-10
EP1227719A4 (en) 2003-01-15
IL149201A0 (en) 2002-11-10
US20110287429A1 (en) 2011-11-24
US20040146865A1 (en) 2004-07-29
US20080085517A1 (en) 2008-04-10
US8551705B2 (en) 2013-10-08
AU1581001A (en) 2001-05-14
CA2388510A1 (en) 2001-05-10
CN1387401A (zh) 2002-12-25
EP1227719A1 (en) 2002-08-07

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