DK1218489T3 - Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf - Google Patents

Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf

Info

Publication number
DK1218489T3
DK1218489T3 DK00965390T DK00965390T DK1218489T3 DK 1218489 T3 DK1218489 T3 DK 1218489T3 DK 00965390 T DK00965390 T DK 00965390T DK 00965390 T DK00965390 T DK 00965390T DK 1218489 T3 DK1218489 T3 DK 1218489T3
Authority
DK
Denmark
Prior art keywords
stem cells
methods
present
pluripotent
relates
Prior art date
Application number
DK00965390T
Other languages
English (en)
Inventor
Henry E Young
Paul A Lucas
Original Assignee
Cybios Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cybios Llc filed Critical Cybios Llc
Priority claimed from PCT/US2000/026225 external-priority patent/WO2001021767A2/en
Application granted granted Critical
Publication of DK1218489T3 publication Critical patent/DK1218489T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
DK00965390T 1999-09-24 2000-09-25 Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf DK1218489T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40489599A 1999-09-24 1999-09-24
US66850800A 2000-09-22 2000-09-22
PCT/US2000/026225 WO2001021767A2 (en) 1999-09-24 2000-09-25 Pluripotent embryonic-like stem cells, compositions, methods and uses thereof

Publications (1)

Publication Number Publication Date
DK1218489T3 true DK1218489T3 (da) 2009-06-02

Family

ID=31720744

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00965390T DK1218489T3 (da) 1999-09-24 2000-09-25 Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf

Country Status (7)

Country Link
US (1) US20100239542A1 (da)
EP (2) EP2333049A1 (da)
JP (8) JP2004504003A (da)
AT (1) ATE426016T1 (da)
DE (1) DE60041821D1 (da)
DK (1) DK1218489T3 (da)
NZ (1) NZ518601A (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009001509A (ja) * 2007-06-19 2009-01-08 Univ Nagoya 脂肪組織由来幹細胞を用いた組織再生用組成物
US9057051B2 (en) 2008-10-31 2015-06-16 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte progenitor phenotypes, cells produced by the methods, and methods of using the cells
US20110020292A1 (en) * 2009-07-21 2011-01-27 Abt Holding Company Use of Stem Cells to Reduce Leukocyte Extravasation
WO2011011500A1 (en) * 2009-07-21 2011-01-27 Abt Holding Company Use of stem cells to reduce leukocyte extravasation
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
SG185526A1 (en) 2010-05-12 2012-12-28 Abt Holding Co Modulation of splenocytes in cell therapy
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
AU2011293440B2 (en) 2010-08-24 2016-05-05 Katholieke Universiteit Leuven Non-static suspension culture of cell aggregates
WO2014123930A2 (en) * 2013-02-05 2014-08-14 Williams Joseph L Prevention and treatment of tissue fibrosis
SG10201710638UA (en) 2013-04-12 2018-01-30 Saverio Lafrancesca Improving organs for transplantation
EP2999780B1 (en) 2013-05-22 2019-10-09 The Regents of the University of California Pluripotent human adipose adult stem cells: isolation, characterization and clinical implications
AU2014296259B2 (en) 2013-07-30 2017-04-27 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
WO2017127123A1 (en) 2016-01-21 2017-07-27 Abt Holding Company Stem cells for wound healing
CN110494592B (zh) 2017-04-13 2021-10-01 日本制铁株式会社 镀Sn钢板以及镀Sn钢板的制造方法
GB2584664B (en) * 2019-06-10 2023-05-24 Newcells Biotech Ltd Improved retinal organoids and methods of making the same
AU2020387259A1 (en) 2019-11-20 2022-06-09 Kyoto University Method for freezing neural cells
KR102179463B1 (ko) * 2019-12-06 2020-11-16 서울대학교 산학협력단 닭의 대흉근으로부터 확립된 근아섬유세포주 및 이를 이용한 생리활성물질 스크리닝 방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31006E (en) 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4491632A (en) 1979-10-22 1985-01-01 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
US4444887A (en) 1979-12-10 1984-04-24 Sloan-Kettering Institute Process for making human antibody producing B-lymphocytes
US4342566A (en) 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
DE3167442D1 (en) 1980-07-07 1985-01-10 Nat Res Dev Improvements in or relating to cell lines
US4341761A (en) 1980-07-25 1982-07-27 E. I. Du Pont De Nemours And Company Antibodies to immunogenic peptides and their use to purify human fibroblast interferon
US4466917A (en) 1981-02-12 1984-08-21 New York University Malaria vaccine
US4493890A (en) 1981-03-23 1985-01-15 Miles Laboratories, Inc. Activated apoglucose oxidase and its use in specific binding assays
US4451570A (en) 1981-03-26 1984-05-29 The Regents Of The University Of California Immunoglobulin-secreting human hybridomas from a cultured human lymphoblastoid cell line
US4399121A (en) 1981-11-04 1983-08-16 Miles Laboratories, Inc. Iodothyronine immunogens and antibodies
US4427783A (en) 1981-12-14 1984-01-24 Hoffmann-La Roche Inc. Immunoassay of thymosin α1
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4493795A (en) 1983-10-17 1985-01-15 Syntex (U.S.A.) Inc. Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture
JPS63216476A (ja) * 1987-03-05 1988-09-08 Rikagaku Kenkyusho 無血清凍結保存用培地
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
JPH06217764A (ja) * 1993-01-22 1994-08-09 Snow Brand Milk Prod Co Ltd 細胞凍結保存用組成物
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
BR9711204A (pt) * 1996-08-19 1999-08-17 Univ Massachusetts Linhagens de c-lulas embriÄnicas ou similares s indiferenciadas produzidas por transplante nuclear de esp-cies hibridas
AU728557B2 (en) * 1996-09-23 2001-01-11 Ontogeny, Inc. Hematopoietic stem cells and methods for generating such cells
US5903934A (en) 1996-10-21 1999-05-18 Sears, Iii; Leonard W. Sanitary fixtures for use with a mobile patient lift
JPH10179165A (ja) * 1996-12-27 1998-07-07 Norin Suisansyo Chikusan Shikenjo 抗体磁気ビーズを用いた生殖幹細胞の分離、精製と幹細胞株の樹立方法
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
CA2296704C (en) * 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
WO1999027076A1 (en) * 1997-11-25 1999-06-03 Arc Genomic Research Pluripotent embryonic stem cells and methods of obtaining them
WO2001011011A2 (en) * 1999-08-05 2001-02-15 Mcl Llc Multipotent adult stem cells and methods for isolation
EP1218489B1 (en) * 1999-09-24 2009-03-18 Cybios LLC Pluripotent embryonic-like stem cells, compositions, methods and uses thereof

Also Published As

Publication number Publication date
ATE426016T1 (de) 2009-04-15
US20100239542A1 (en) 2010-09-23
JP2018174948A (ja) 2018-11-15
JP6545335B2 (ja) 2019-07-17
EP2333049A1 (en) 2011-06-15
JP2014054258A (ja) 2014-03-27
JP6539188B2 (ja) 2019-07-03
JP2019076094A (ja) 2019-05-23
JP2011167198A (ja) 2011-09-01
NZ518601A (en) 2004-10-29
JP2011103885A (ja) 2011-06-02
JP2016063818A (ja) 2016-04-28
JP2004504003A (ja) 2004-02-12
EP1903107A1 (en) 2008-03-26
JP2017079792A (ja) 2017-05-18
DE60041821D1 (de) 2009-04-30

Similar Documents

Publication Publication Date Title
WO2001021767A3 (en) Pluripotent embryonic-like stem cells, compositions, methods and uses thereof
DK1218489T3 (da) Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf
SE0201328D0 (sv) Hematopoietic differentiation of human embryonic stem cells
EA200601187A1 (ru) Стволовые клетки
DE59912118D1 (de) Verfahren zur herstellung von genetisch modifizierten cd34-negativen, adhärent wachsenden hämatopoietischen stammzellen
EP2368974A1 (en) Methods for isolating mesenchymal stem cells from embryos of human or animals and extracting secretion substances thereof
US7781211B2 (en) Isolation of multi-lineage stem cells
ATE365793T1 (de) Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe
SG150387A1 (en) Apparatus and methods for amplification of blood stem cell numbers
WO2003023018A3 (en) A method for isolating, culturing and differentiating intestinal stem cells for therapeutic use
US20200224170A1 (en) Stem cell compositions and methods of producing stem cells for therapeutic applications
JP2010539970A5 (da)
ES2611922T3 (es) Células madre pluripotenciales obtenidas a partir de la pulpa dental
CN103497892B (zh) 一种细胞培养基材及其制备方法和应用
US8796020B2 (en) Manufacturing process for fresh and frozen stem cells
De Chiara et al. Characterization of human mesenchymal stem cells isolated from the testis
WO2005056755A3 (en) Compositions and methods for propagation of neural progenitor cells
CN104726401A (zh) 一种利用胎盘间充质干细胞提高脐血间充质干细胞培养成功率的方法
CN102822331A (zh) 提高人干细胞活性的方法
Fu et al. Vitrification of rhesus macaque mesenchymal stem cells and the effects on global gene expression
CN106318979A (zh) 诱导间充质干细胞转分化为皮肤干细胞的方法
CN106834207A (zh) 一种中华鳖卵巢细胞分离及体外培养方法
US20080299656A1 (en) Isolation of multi-lineage stem cells
CN101016540A (zh) C－端含有组氨酸标记的hoxb4重组蛋白质的制造方法及用途
TW201111502A (en) Method for extracting mesenchymal stem cell from embryo of animals and human, and method for extracting secretion from the extracting mesenchymal stem cell