BR0015264A - Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética - Google Patents

Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética

Info

Publication number
BR0015264A
BR0015264A BR0015264-1A BR0015264A BR0015264A BR 0015264 A BR0015264 A BR 0015264A BR 0015264 A BR0015264 A BR 0015264A BR 0015264 A BR0015264 A BR 0015264A
Authority
BR
Brazil
Prior art keywords
multiplication
diagnosis
haploid genomes
genomes
cells
Prior art date
Application number
BR0015264-1A
Other languages
English (en)
Inventor
James M Robl
Pedro Moreira
Original Assignee
Univ Massachusetts Public Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts Public Inst filed Critical Univ Massachusetts Public Inst
Publication of BR0015264A publication Critical patent/BR0015264A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"USO DE GENOMAS HAPLóIDES PARA DIAGNóSTICO, MODIFICAçãO E MULTIPLICAçãO GENéTICA". Métodos para propagação de genomas haplóides de origem masculina ou feminina e avaliação e modificação genética deles são providos. Esses genomas haplóides podem ser usados para produzir embriões haplóides, e células do tipo tronco embriónicas e células diferenciadas. Também, esses genomas haplóide e células que os contêm podem ser usados como doadores de transferência nuclear para produzir unidades de transferência nuclear diplóides. Essas unidades diplóides, por exemplo, unidades humanas, podem ser usadas para se obter células pluripotentes e células e tecidos diferenciados.
BR0015264-1A 1999-11-02 2000-11-02 Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética BR0015264A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16308699P 1999-11-02 1999-11-02
PCT/US2000/030202 WO2001032015A1 (en) 1999-11-02 2000-11-02 Use of haploid genomes for genetic diagnosis, modification and multiplication

Publications (1)

Publication Number Publication Date
BR0015264A true BR0015264A (pt) 2002-10-15

Family

ID=22588424

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015264-1A BR0015264A (pt) 1999-11-02 2000-11-02 Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética

Country Status (10)

Country Link
US (3) US20040146865A1 (pt)
EP (1) EP1227719A4 (pt)
JP (1) JP2003512848A (pt)
CN (1) CN1387401A (pt)
AU (1) AU1581001A (pt)
BR (1) BR0015264A (pt)
CA (1) CA2388510A1 (pt)
IL (1) IL149201A0 (pt)
MX (1) MXPA02004333A (pt)
WO (1) WO2001032015A1 (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025088D0 (en) * 2000-10-13 2000-11-29 Univ Edinburgh Stem cells
AU2001297880B2 (en) * 2000-11-30 2007-05-31 Stemron Inc. Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same
EP1356035B1 (en) * 2000-12-22 2011-03-16 Kyowa Hakko Kirin Co., Ltd. Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
US7491534B2 (en) * 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
JP4223284B2 (ja) * 2001-01-02 2009-02-12 ステムロン インコーポレイテッド 予め選抜されたイムノタイプおよび／またはジェノタイプを有するホモ接合性幹細胞群の製造方法、該細胞由来の移植に適切な細胞、並びにこれらを用いた材料および方法
EP2679671B1 (en) * 2002-05-24 2019-12-11 Advanced Cell Technology, Inc. A bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
WO2006041910A2 (en) * 2004-10-05 2006-04-20 Trustees Of The University Of Pennsylvania Stem cells derived from uniparental embryos and methods of use thereof
US20080215353A1 (en) * 2006-08-31 2008-09-04 Akin James W Method of Frozen Donor Egg Banking
US20080167851A1 (en) * 2007-01-08 2008-07-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for genome selection
US8012740B2 (en) * 2007-01-08 2011-09-06 The Invention Science Fund I, Llc Systems for genome selection
US7947455B2 (en) * 2007-01-08 2011-05-24 The Invention Science Fund I, Llc System for genome selection
US8003371B2 (en) 2007-01-08 2011-08-23 The Invention Science Fund I, Llc Systems for genome selection
US7985578B2 (en) 2007-01-08 2011-07-26 The Invention Science Fund I, Llc Systems for genome selection
US8521440B2 (en) * 2007-01-08 2013-08-27 The Invention Science Fund I, Llc Systems for genome selection
US7713728B2 (en) * 2007-01-08 2010-05-11 The Invention Sciencefund I, Llc Systems for genome selection
US7709244B2 (en) * 2007-01-08 2010-05-04 The Invention Science Fund I, Llc Systems for genome selection
US7648823B2 (en) * 2007-01-08 2010-01-19 Searete Llc Systems for genome selection
US7709245B2 (en) * 2007-01-08 2010-05-04 The Invention Science Fund I, Llc Systems for genome selection
US7718418B2 (en) 2007-01-08 2010-05-18 The Invention Science Fund I, Llc Systems for genome selection
US7947457B2 (en) * 2007-01-08 2011-05-24 The Invention Science Fund I, Llc Systems for genome selection
US20090111184A1 (en) * 2007-10-24 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Chromosome selection
US20090111764A1 (en) * 2007-10-25 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Mitochondrial selection
US20090111185A1 (en) * 2007-10-26 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Female genome selection
WO2012071393A2 (en) * 2010-11-23 2012-05-31 The New York Stem Cell Foundation Method for producing pluripotent stem cells
WO2012117254A1 (en) * 2011-03-02 2012-09-07 Cambridge Enterprise Limited Mammalian haploid embryonic stem cells
CN102533970A (zh) * 2011-11-14 2012-07-04 江苏迈健生物科技发展有限公司 一种反转录pcr分析ivf单个植入前胚胎的基因表达方法
EP2599859A1 (en) 2011-11-30 2013-06-05 IMBA-Institut für Molekulare Biotechnologie GmbH Haploid cells
IL293110B2 (en) 2015-03-23 2023-11-01 Astellas Inst For Regenerative Medicine Improved assays for the potential of retinal pigment epithelium (RPE) cells and photoreceptor progenitors
EP3349573A1 (en) * 2015-09-17 2018-07-25 Regeneron Pharmaceuticals, Inc. Selection of pluripotent cells for production of fertile xy female mice
US11859232B2 (en) * 2016-06-19 2024-01-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Screening for chemotherapy resistance in human haploid cells
EP3421593A1 (en) * 2017-06-30 2019-01-02 Centre National De La Recherche Scientifique Method for obtaining haploid cells
BR112021016011A2 (pt) * 2019-02-20 2021-10-05 The Semex Alliance Uso de células embrionárias haploides para gerar descendentes com genomas predeterminados
CN112375829B (zh) * 2020-11-25 2022-07-05 苏州赛美科基因科技有限公司 使用家系wes数据识别upd的方法、装置及电子设备

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480772A (en) * 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5749169A (en) * 1995-06-07 1998-05-12 Pioneer Hi-Bred International, Inc. Use of the indeterminate gametophyte gene for maize improvement
US5932418A (en) * 1996-04-08 1999-08-03 Naiad Systems, Inc. Fish embryo screening test for genotoxic agents using three different developmental life stages
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
CN100497598C (zh) * 1999-10-28 2009-06-10 马萨诸塞大学 多能细胞和细胞系的单雌生殖或单雄生殖产生,及其产生分化细胞和组织的用途

Also Published As

Publication number Publication date
US20110287429A1 (en) 2011-11-24
JP2003512848A (ja) 2003-04-08
US8551705B2 (en) 2013-10-08
IL149201A0 (en) 2002-11-10
AU1581001A (en) 2001-05-14
EP1227719A1 (en) 2002-08-07
MXPA02004333A (es) 2004-04-21
CN1387401A (zh) 2002-12-25
US20040146865A1 (en) 2004-07-29
CA2388510A1 (en) 2001-05-10
EP1227719A4 (en) 2003-01-15
WO2001032015A1 (en) 2001-05-10
US20080085517A1 (en) 2008-04-10

Similar Documents

Publication Publication Date Title
BR0015264A (pt) Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética
BR0312764A (pt) Cardiomiócitos funcionais originados de células-tronco embrionárias humanas
HUP9802485A2 (hu) Inaktivált oociták, mint citoplaszt befogadók, sejtmagátültetés esetében
HUP0500477A2 (hu) Eljárások és készítmények embrionális és felnőttkori őssejtek támogatására stromasejtek alkalmazásával
HK1049350A1 (en) Multipotent adult stem cells and methods for isolation
BR9814568A (pt) "inseminação sexual especìfica de mamìferos com baixo número de células espermatozóides"
TW200712208A (en) Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
BR0305721A (pt) Célula-tronco humana, população de células, processo para obtenção de células-tronco, para a produção de células diferenciadas da linhagem mesodérmica, para seleção que permite identificar agentes suscetìveis de apresentar uma atividade lipolìtica e uma atividade insulino-sensibilizante, utilização de uma célula, utilização de células-tronco, composição farmacêutica, célula humana, população celular humana multipotente
WO2003006950A3 (en) Cells of the cardiomyocyte lineage produced from human pluripotent stem cells
ATE556137T1 (de) Durch einen polyelektrolytkomplex von hyaluronsäure und chitosan verstärkte biomimetische zusammensetzung
FR2812004B1 (fr) Milieux de culture pour fecondation in vitro, ou pour la culture de follicules, cellules germinales males ou embryons
Smajdor et al. Artificial gametes and the ethics of unwitting parenthood
ATE15693T1 (de) Zellkultur-verfahren.
NO20016184L (no) Frakoblingsoverflate
PH12020551584A1 (en) Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them
Tang et al. Generation of a Bag1 homozygous knockout mouse embryonic stem cell line using CRISPR/Cas9
HUP0101393A1 (hu) Redukáló körülményekre érzékeny transzfektáló kompozíciók, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
Chowdhury et al. Stem cells an overview
Zhao et al. Contribution to neural and mesodermal lineages by porcine skin-derived progenitors (SKPs) in vivo
DE50009932D1 (de) Gentransfer in humane lymphocyten mittels retroviraler scfv-zelltargeting vektoren
BR9909044A (pt) Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante
Liu Expanded Potential Stem Cells: A New Tool For Basic And Translational Research
Beardsley Embryo sexing. Cattle now, people next?
Pääbo Human origins from a genomic perspective
Josefson Embryos created for stem cell research

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.