BR9909044A - Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante - Google Patents

Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante

Info

Publication number
BR9909044A
BR9909044A BR9909044-9A BR9909044A BR9909044A BR 9909044 A BR9909044 A BR 9909044A BR 9909044 A BR9909044 A BR 9909044A BR 9909044 A BR9909044 A BR 9909044A
Authority
BR
Brazil
Prior art keywords
nucleic acid
acid transfer
transfer vector
cells
composition
Prior art date
Application number
BR9909044-9A
Other languages
English (en)
Inventor
Carole Ciolina
Daniel Scherman
Pierre Wils
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9803573A external-priority patent/FR2776669B1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BR9909044A publication Critical patent/BR9909044A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A61K48/0025Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"VETOR DE TRANSFERêNCIA DE áCIDOS NUCLEICOS, COMPOSIçãO, UTILIZAçãO DE UM VETOR DE TRANSFERêNCIA DE áCIDOS NUCLEICOS, PROCESSOS DE TRANSFECçãO DE áCIDOS NUCLEICOS NAS CéLULAS, E DE TRATAMENTO DE DOENçAS, E, CéLULA RECOMBINANTE". A presente invenção refere-se a novos vetores e sua utilização para a transferência de ácidos nucleicos. Mais particularmente, a invenção refere-se a novos vetores capazes de dirigir os ácidos nucleicos para as células ou os compartimentos celulares específicos.
BR9909044-9A 1998-03-24 1999-03-19 Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante BR9909044A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9803573A FR2776669B1 (fr) 1998-03-24 1998-03-24 Vecteurs de transfert d'acides nucleiques, compositions les contenant, et leurs utilisations
US8584898P 1998-05-18 1998-05-18
PCT/FR1999/000643 WO1999049067A1 (fr) 1998-03-24 1999-03-19 Vecteurs de transfert d'acides nucleiques, compositions les contenant, et leurs utilisations

Publications (1)

Publication Number Publication Date
BR9909044A true BR9909044A (pt) 2000-12-05

Family

ID=26234216

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909044-9A BR9909044A (pt) 1998-03-24 1999-03-19 Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante

Country Status (12)

Country Link
EP (1) EP1066396A1 (pt)
JP (1) JP2002507429A (pt)
KR (1) KR20010074456A (pt)
CN (1) CN1292827A (pt)
AU (1) AU758406B2 (pt)
BR (1) BR9909044A (pt)
CA (1) CA2323831A1 (pt)
HU (1) HUP0102413A3 (pt)
IL (1) IL138624A0 (pt)
NO (1) NO20004648D0 (pt)
PL (1) PL342944A1 (pt)
WO (1) WO1999049067A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2298239T3 (es) * 2000-05-26 2008-05-16 Centelion Purificacion de una formacion de triple helice con oligonucleotido inmovilizado.
FR2871465B1 (fr) * 2004-06-15 2006-09-08 Centre Nat Rech Scient Cnrse Collections de composes tracables et leurs utilisations
US7943589B2 (en) 2005-06-03 2011-05-17 President And Fellows Of Harvard College siRNA microbicides for preventing and treating diseases
US7795380B2 (en) 2006-06-02 2010-09-14 University Of Iowa Research Foundation Compositions and methods for nucleic acid delivery
EP3427054A4 (en) * 2016-03-07 2019-12-04 Quidel Cardiovascular Inc. IMMUNOASSAY CHECKS AND USE THEREOF
RU2731513C2 (ru) * 2018-12-21 2020-09-03 Селл энд Джин Терапи Лтд Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов NOS2, NOS3, VIP, KCNMA1, CGRP, для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-NOS2, или Escherichia coli SCS110-AF/VTvaf17-NOS3, или Escherichia coli SCS110-AF/VTvaf17-VIP, или Escherichia coli SCS110-AF/VTvaf17-KCNMA1, или Escherichia coli SCS110-AF/VTvaf17-CGRP, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2028792A (en) * 1991-05-17 1992-12-30 Uab Research Foundation Sequence specific dna binding drugs
US5670347A (en) * 1994-05-11 1997-09-23 Amba Biosciences Llc Peptide-mediated gene transfer
FR2731014B1 (fr) * 1995-02-23 1997-03-28 Rhone Poulenc Rorer Sa Molecules d'adn, preparation et utilisation en therapie genique

Also Published As

Publication number Publication date
AU758406B2 (en) 2003-03-20
EP1066396A1 (fr) 2001-01-10
KR20010074456A (ko) 2001-08-04
NO20004648L (no) 2000-09-18
CN1292827A (zh) 2001-04-25
JP2002507429A (ja) 2002-03-12
IL138624A0 (en) 2001-10-31
NO20004648D0 (no) 2000-09-18
HUP0102413A3 (en) 2003-09-29
CA2323831A1 (fr) 1999-09-30
AU3406200A (en) 2000-12-14
WO1999049067A1 (fr) 1999-09-30
HUP0102413A1 (hu) 2001-10-28
PL342944A1 (en) 2001-07-16

Similar Documents

Publication Publication Date Title
AR006188A1 (es) "composicion farmaceutica para inhibir la actividad de serinproteasa, metodo in vitro para inhibir la actividad de serinproteasa y metodo para preparar dicha composicion".
ES2147553T3 (es) Vectores virales recombinantes para la expresion en unas celulas musculares.
BG102554A (en) Vectors and methods for gene transfer into cells
BR9910251A (pt) Estimulação hematopoiética
BR9810369A (pt) Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação
BR0316234A (pt) Hidroxiindóis, seu uso como inibidores de fosfodiesterase 4 e processos para a preparação dos mesmos
BR0007663A (pt) Derivados de acila para uso no tratamento de doenças relacionadas com o vla-4
MX9800719A (es) Proteinas de transporte y sus usos.
BR0010496A (pt) Regulação da expressão genica viral
DE50013093D1 (de) Sequenz-spezifische dna-rekombination in eukaryotischen zellen
WO1999033980A3 (en) Members of tnf and tnfr families
FR2470794A1 (fr) Nouvelles microparticules, leur preparation et leurs applications en biologie, notamment a la culture de cellules diploides humaines
CY1108603T1 (el) Συστηματα πρωτεϊνων μεταφορας λιπιδιων και η καλλυντικη δερματολογικη εφαρμογη τους
BR9809506A (pt) Composto, composição, utilização de um composto, e, processos para preparação de um composto e para transferência de ácidos nucleicos para o interior das células
ATE215099T1 (de) Kationische polymere, diese kationische polymere enthaltende komplexe und wenigstens eine negative ladung enthaltende therapeutisch wirksame mittel, insbesondere nukleinsäuren und ihre verwendung in gentherapie
TR199801840A2 (xx) Yeni imidazolidin t�revleri ve bunlar� i�eren farmakolojik preparatlar.
TR199802648A2 (xx) Gen tedavisi i�in n�klein asit yap�lar�.
TR200002248T2 (tr) Yeni dihidroksiheksanoik asit türevleri
BR9909044A (pt) Vetor de tranferência de ácidos nucleicos, composição, utilização de um vetor de tranferência de ácidos nucleicos, processos de transfecção de ácidos nucleicos nas células, e de tratamento de doenças, e, célula recombinante
ATE386130T1 (de) Adenovirale vektoren für die gentherapie
DE60037978D1 (de) Interferon ähnliche moleküle, und deren verwendungen
HUP9800613A2 (hu) Humán Fas-antigén elleni humanizált antitest
BR9507473A (pt) Sequéncia de dna isolada vetor célula hospedeira processo para produzir uma proteina gp350 homogénea proteína gp350 homogénea composição farmacéutica e uso na proteina gp350 homogénea
BR9908443A (pt) Linhagens de células de medula espinhal humana e métodos para uso das mesmas
CA2385872A1 (en) Gene transfer in human lymphocytes using retroviral scfv cell targeting

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.