BR9908443A - Linhagens de células de medula espinhal humana e métodos para uso das mesmas - Google Patents
Linhagens de células de medula espinhal humana e métodos para uso das mesmasInfo
- Publication number
- BR9908443A BR9908443A BR9908443-0A BR9908443A BR9908443A BR 9908443 A BR9908443 A BR 9908443A BR 9908443 A BR9908443 A BR 9908443A BR 9908443 A BR9908443 A BR 9908443A
- Authority
- BR
- Brazil
- Prior art keywords
- cell lines
- spinal cord
- methods
- human spinal
- cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
"LINHAGENS DE CéLULAS DE MEDULA ESPINHAL HUMANA E MéTODOS PARA USO DAS MESMAS". A presente invenção refere-se a linhagens de células de medula espinhal humana condicionalmente imortalizadas. Tais linhagens de células, que podem ser clonais, podem ser usadas para gerar neurónios, incluindo motoneurónios. As linhagens de células e/ou células diferenciadas podem ser usadas para o desenvolvimento de agentes terapêuticos para prevenir e tratar uma variedade de doenças e ferimentos relacionadas a medula espinhal. As linhagens de células e/ou células diferenciadas podem ser usadas em ensaios e para o estudo geral do desenvolvimento e direferenciação de células de medula espinhal.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7656798P | 1998-03-02 | 1998-03-02 | |
US09/059,790 US6225122B1 (en) | 1998-03-02 | 1998-04-13 | Human spinal cord cell lines and methods of use therefor |
PCT/US1999/004535 WO1999045103A2 (en) | 1998-03-02 | 1999-03-02 | Human spinal cord cell lines and methods of use therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9908443A true BR9908443A (pt) | 2002-01-15 |
Family
ID=26739180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9908443-0A BR9908443A (pt) | 1998-03-02 | 1999-03-02 | Linhagens de células de medula espinhal humana e métodos para uso das mesmas |
Country Status (7)
Country | Link |
---|---|
US (1) | US6225122B1 (pt) |
EP (1) | EP1060245A2 (pt) |
CN (1) | CN1297477A (pt) |
AU (1) | AU3065599A (pt) |
BR (1) | BR9908443A (pt) |
CA (1) | CA2322747A1 (pt) |
WO (1) | WO1999045103A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7037493B2 (en) | 2000-05-01 | 2006-05-02 | Cornell Research Foundation, Inc. | Method of inducing neuronal production in the brain and spinal cord |
US20030077564A1 (en) * | 2001-10-02 | 2003-04-24 | Board Of Trustees Of Southern Illinois University | Nutrient medium for maintaining neural cells in injured nervous system |
US6770521B2 (en) * | 2001-11-30 | 2004-08-03 | Texas Instruments Incorporated | Method of making multiple work function gates by implanting metals with metallic alloying additives |
WO2003050273A1 (fr) * | 2001-12-13 | 2003-06-19 | Japan Science And Technology Agency | Milieu de culture pour des cellules humaines et methode de culture |
AU2003215297A1 (en) * | 2002-02-15 | 2003-09-09 | Cornell Research Foundation, Inc. | Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein |
WO2006138718A2 (en) * | 2005-06-17 | 2006-12-28 | Drexel University | Three-dimensional scaffolds for tissue engineering made by processing complex extracts of natural extracellular matrices |
WO2015017354A1 (en) * | 2013-07-29 | 2015-02-05 | University Of Houston System | Volatile organic gases as bioindicators for transplant rejection |
US11156595B2 (en) * | 2015-05-28 | 2021-10-26 | Axogen Corporation | Organotypic DRG-peripheral nerve culture system |
EP3332695B1 (en) * | 2016-12-09 | 2021-05-26 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Measurement device |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU222040B1 (hu) | 1994-11-08 | 2003-04-28 | Cellfactors Plc | Eljárás humán porc, csont és neurális sejtvonalak előállítására |
US5770414A (en) | 1996-02-20 | 1998-06-23 | The Regents Of The University Of California | Regulatable retrovirus system for genetic modification of cells |
US6713247B1 (en) | 1996-09-03 | 2004-03-30 | Signal Pharmaceuticials, Inc. | Human CNS cell lines and methods of use therefor |
-
1998
- 1998-04-13 US US09/059,790 patent/US6225122B1/en not_active Expired - Lifetime
-
1999
- 1999-03-02 CA CA002322747A patent/CA2322747A1/en not_active Abandoned
- 1999-03-02 CN CN99805214A patent/CN1297477A/zh active Pending
- 1999-03-02 AU AU30655/99A patent/AU3065599A/en not_active Abandoned
- 1999-03-02 BR BR9908443-0A patent/BR9908443A/pt not_active Application Discontinuation
- 1999-03-02 EP EP99912239A patent/EP1060245A2/en not_active Withdrawn
- 1999-03-02 WO PCT/US1999/004535 patent/WO1999045103A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2322747A1 (en) | 1999-09-10 |
WO1999045103A2 (en) | 1999-09-10 |
AU3065599A (en) | 1999-09-20 |
EP1060245A2 (en) | 2000-12-20 |
CN1297477A (zh) | 2001-05-30 |
US6225122B1 (en) | 2001-05-01 |
WO1999045103A3 (en) | 1999-11-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |