SG10201913789VA - Selection of pluripotent cells for production of fertile xy female mice - Google Patents

Selection of pluripotent cells for production of fertile xy female mice

Info

Publication number
SG10201913789VA
SG10201913789VA SG10201913789VA SG10201913789VA SG10201913789VA SG 10201913789V A SG10201913789V A SG 10201913789VA SG 10201913789V A SG10201913789V A SG 10201913789VA SG 10201913789V A SG10201913789V A SG 10201913789VA SG 10201913789V A SG10201913789V A SG 10201913789VA
Authority
SG
Singapore
Prior art keywords
fertile
selection
production
pluripotent cells
female mice
Prior art date
Application number
SG10201913789VA
Inventor
Jennifer Schmahl
David Frendewey
Junko Kuno
Chia-Jen Siao
Gustavo Droguett
Yu Bai
Wojtek Auerbach
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG10201913789VA publication Critical patent/SG10201913789VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates
    • A01K67/0271Chimeric animals, e.g. comprising exogenous cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073Stem cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/12Animals modified by administration of exogenous cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/35Animals modified by environmental factors, e.g. temperature, O2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
SG10201913789VA 2015-09-17 2016-09-16 Selection of pluripotent cells for production of fertile xy female mice SG10201913789VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562219927P 2015-09-17 2015-09-17

Publications (1)

Publication Number Publication Date
SG10201913789VA true SG10201913789VA (en) 2020-03-30

Family

ID=57113699

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201913789VA SG10201913789VA (en) 2015-09-17 2016-09-16 Selection of pluripotent cells for production of fertile xy female mice

Country Status (13)

Country Link
US (2) US10893666B2 (en)
EP (1) EP3349573A1 (en)
JP (1) JP6868615B2 (en)
KR (1) KR102382458B1 (en)
CN (1) CN108697068B (en)
AU (1) AU2016324305B2 (en)
CA (1) CA2998642C (en)
HK (1) HK1256687A1 (en)
IL (1) IL257982B2 (en)
MX (1) MX2018003354A (en)
RU (1) RU2729407C1 (en)
SG (1) SG10201913789VA (en)
WO (1) WO2017049240A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108998540A (en) * 2018-08-18 2018-12-14 兰州大学 The single nucleotide polymorphism of sheep EIF2S3Y gene and its detection primer, kit, method and application
CN110656167A (en) * 2019-09-27 2020-01-07 中国科学院苏州生物医学工程技术研究所 Primer group and kit for detecting microdeletion of Y chromosome and detection method based on digital PCR
CN111321232B (en) * 2020-03-18 2022-08-16 西北农林科技大学 Method for rapidly detecting copy number variation of EIF4A2 gene of beef cattle and application thereof
CN113558012A (en) * 2021-08-05 2021-10-29 陈米米 Method for breeding female multiple births by using mammals
CN114015705A (en) * 2021-11-28 2022-02-08 华中科技大学同济医学院附属协和医院 Sex selection method for mouse in-vitro fertilization breeding
CN115251007B (en) * 2022-09-02 2024-01-26 山西医科大学 New-line nude rat, and cultivation method and application thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000508919A (en) 1996-04-29 2000-07-18 リューベン・リサーチ・アンド・デベロップメント・ベー・ゼット・ウェー Pluripotent rabbit embryonic stem (ES) cell line and its use in developing chimeric rabbits
EP1067141A1 (en) * 1999-06-11 2001-01-10 Rijksuniversiteit te Leiden A male-specific protein homologue involved in histocompatibility
JP2003512848A (en) 1999-11-02 2003-04-08 ユニバーシティ オブ マサチューセッツ、アズ リプリゼンティッド バイ イッツ アマースト キャンパス Use of haploid genomes for genetic diagnosis, modification and propagation
EP1241936A4 (en) 1999-12-20 2006-04-05 Anthony C F Perry A method to produce cloned embryos and adults from cultured cells
CN1649489A (en) 2002-02-27 2005-08-03 长尾恭光 Method of constructing germline chimeric animal
DE60301953T2 (en) 2002-03-05 2006-07-27 Artemis Pharmaceuticals Gmbh MICE DERIVED FROM INNOVATION MALE DERIVED FROM EMBRYONIC STEM CELLS
EP1516924A1 (en) 2003-09-17 2005-03-23 Fundacion IVI para el Estudio de la reproduccion Humana (FIVIER) Generation of human embryonic stem cells from triploid zygotes
AU2005224569B2 (en) 2004-03-23 2011-07-14 Toshihiro Akaike Method of proliferating pluripotent stem cell
EP1802193B1 (en) 2004-10-19 2014-04-30 Regeneron Pharmaceuticals, Inc. Method for generating a mouse homozygous for a genetic modification
BRPI0714257A8 (en) 2006-08-09 2017-05-09 Valneva "METHODS FOR CULTURE OF AVIAN EMBRYONIC STEM CELLS (ES), FOR GENETICALLY MODIFYING EMBRYONIC STEM CELLS, FOR OBTAINING A CHIMERIC CHICK, FOR OBTAINING CHICK PROGENY, FOR ANALYSIS OF GENETIC POLYMORPHISM, CULTURE MEDIA FOR AVIAN EMBRYONIC STEM CELLS AND CULTURE MEDIA".
GB0623635D0 (en) 2006-11-27 2007-01-03 Stem Cell Sciences Uk Ltd Pluripotent cell growth media
WO2009037337A1 (en) 2007-09-20 2009-03-26 Novartis Ag Robust and tissue independent gender-specific transcript markers for molecular gender determination
CA2751596A1 (en) 2009-02-08 2010-08-12 The University Of Melbourne Sex-determination and methods of specifying same
AU2010306377B2 (en) 2009-10-13 2015-01-22 Stemcell Technologies Canada Inc. Manipulation of osmolality for differentiating stem cells
ES2727738T3 (en) * 2010-06-11 2019-10-18 Regeneron Pharma Production of fertile xy female animals from cells is xy
WO2012022634A1 (en) * 2010-08-16 2012-02-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Classification, diagnosis and prognosis of multiple myeloma
RU2711740C2 (en) 2014-06-26 2020-01-21 Регенерон Фармасьютикалз, Инк. Methods and compositions for targeted genetic modifications and methods for use thereof
KR20170070136A (en) 2014-10-15 2017-06-21 리제너론 파마슈티칼스 인코포레이티드 Methods and compositions for generating or maintaining pluripotent cells

Also Published As

Publication number Publication date
EP3349573A1 (en) 2018-07-25
IL257982B2 (en) 2023-05-01
RU2729407C1 (en) 2020-08-06
MX2018003354A (en) 2018-05-28
HK1256687A1 (en) 2019-10-04
NZ740899A (en) 2021-11-26
AU2016324305A9 (en) 2019-01-03
US10893666B2 (en) 2021-01-19
KR102382458B1 (en) 2022-04-04
US20170079250A1 (en) 2017-03-23
AU2016324305A1 (en) 2018-04-12
CN108697068B (en) 2022-02-11
JP6868615B2 (en) 2021-05-12
WO2017049240A8 (en) 2018-05-24
US20210112788A1 (en) 2021-04-22
WO2017049240A1 (en) 2017-03-23
AU2016324305B2 (en) 2022-03-03
CA2998642A1 (en) 2017-03-23
CA2998642C (en) 2023-09-12
CN108697068A (en) 2018-10-23
IL257982A (en) 2018-05-31
IL257982B1 (en) 2023-01-01
KR20180058731A (en) 2018-06-01
JP2018527005A (en) 2018-09-20

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