JP2018523999A5 - - Google Patents

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Publication number
JP2018523999A5
JP2018523999A5 JP2017568252A JP2017568252A JP2018523999A5 JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5 JP 2017568252 A JP2017568252 A JP 2017568252A JP 2017568252 A JP2017568252 A JP 2017568252A JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5
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JP
Japan
Prior art keywords
gene
handii
tbx5
nkx2
human
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Pending
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JP2017568252A
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English (en)
Japanese (ja)
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JP2018523999A (ja
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Priority claimed from PCT/US2016/040431 external-priority patent/WO2017004388A1/en
Publication of JP2018523999A publication Critical patent/JP2018523999A/ja
Publication of JP2018523999A5 publication Critical patent/JP2018523999A5/ja
Pending legal-status Critical Current

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JP2017568252A 2015-06-30 2016-06-30 ヒト化心筋 Pending JP2018523999A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562187040P 2015-06-30 2015-06-30
US62/187,040 2015-06-30
PCT/US2016/040431 WO2017004388A1 (en) 2015-06-30 2016-06-30 Humanized heart muscle

Publications (2)

Publication Number Publication Date
JP2018523999A JP2018523999A (ja) 2018-08-30
JP2018523999A5 true JP2018523999A5 (https=) 2019-08-08

Family

ID=57609529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017568252A Pending JP2018523999A (ja) 2015-06-30 2016-06-30 ヒト化心筋

Country Status (13)

Country Link
US (2) US10897880B2 (https=)
EP (1) EP3316899A4 (https=)
JP (1) JP2018523999A (https=)
KR (1) KR20180021135A (https=)
CN (1) CN108472318A (https=)
AU (1) AU2016288671A1 (https=)
BR (1) BR112017028608A2 (https=)
CA (1) CA2991056A1 (https=)
CO (1) CO2018000859A2 (https=)
IL (1) IL256544A (https=)
MX (1) MX2018000071A (https=)
RU (1) RU2018103234A (https=)
WO (1) WO2017004388A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102684690B1 (ko) 2015-03-03 2024-07-15 리젠츠 오브 더 유니버시티 오브 미네소타 Etv2 및 그의 용도
WO2017004388A1 (en) 2015-06-30 2017-01-05 Regents Of The University Of Minnesota Humanized heart muscle
RU2018103093A (ru) 2015-06-30 2019-07-31 Реджентс Оф Зэ Юниверсити Оф Миннесота Гуманизированная скелетная мышца

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997025412A1 (en) * 1996-01-09 1997-07-17 The Regents Of The University Of California Ungulate embryonic stem-like cells, methods of making and using the cells to produce transgenic ungulates
US5994619A (en) * 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
CN1241210A (zh) * 1996-10-11 2000-01-12 得克萨斯农业及机械体系综合大学 产生原生殖细胞和转基因动物物种的方法
US20050039222A1 (en) 2001-10-24 2005-02-17 Kiyoshi Habu Sgrf gene-modified non-human animals
US20040133931A1 (en) 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
US20050125853A1 (en) 2002-03-22 2005-06-09 St. Jude Children's Resarch Hospital Method for generating genetically modified animals
CA2488725A1 (en) * 2002-07-03 2004-01-15 Su Qian Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
GB2398784B (en) * 2003-02-26 2005-07-27 Babraham Inst Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal
US20060008451A1 (en) 2004-07-06 2006-01-12 Michigan State University In vivo methods for effecting tissue specific differentiation of embryonic stem cells
JP5425641B2 (ja) 2007-01-11 2014-02-26 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 尿路病状の処置のための筋由来細胞ならびにその作製および使用の方法
US20100107263A1 (en) 2007-01-20 2010-04-29 Boehringer Ingelheim International Gmbh & Co., Kg C-reactive protein (crp) knockout mouse
JPWO2008102602A1 (ja) * 2007-02-22 2010-05-27 国立大学法人 東京大学 Blastocystcomplementationを利用した臓器再生法
JP5688788B2 (ja) 2008-02-22 2015-03-25 国立大学法人 東京大学 遺伝子改変による致死性表現型を持つ動物の繁殖用ファウンダー動物作製法
GB2490443B8 (en) 2008-08-22 2014-08-13 Univ Tokyo Organ regeneration method utilizing iPS cell and blastocyst complementation
WO2010108126A2 (en) 2009-03-19 2010-09-23 Fate Therapeutics, Inc. Reprogramming compositions and methods of using the same
CA2762584A1 (en) * 2009-05-20 2010-11-25 Cardio3 Biosciences S.A. Pharmaceutical composition for the treatment of heart diseases
AU2012249390B2 (en) 2011-04-27 2017-03-30 Amyris, Inc. Methods for genomic modification
AU2012262139B2 (en) * 2011-06-02 2017-02-23 Children's Medical Center Corporation Methods and uses for ex vivo tissue culture systems
US9862929B2 (en) 2011-11-18 2018-01-09 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
IL221187A (en) 2012-07-30 2017-01-31 Adom Advanced Optical Tech Ltd A system to perform optical tomography in two 2D beams
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
US11377639B2 (en) * 2013-11-15 2022-07-05 Wisconsin Alumni Research Foundation Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
BR112016024945A2 (pt) 2014-04-28 2017-10-24 Recombinetics Inc edição de gene multiplex em suínos
KR102684690B1 (ko) 2015-03-03 2024-07-15 리젠츠 오브 더 유니버시티 오브 미네소타 Etv2 및 그의 용도
RU2018103093A (ru) 2015-06-30 2019-07-31 Реджентс Оф Зэ Юниверсити Оф Миннесота Гуманизированная скелетная мышца
WO2017004388A1 (en) 2015-06-30 2017-01-05 Regents Of The University Of Minnesota Humanized heart muscle
EP3367785A4 (en) 2015-10-27 2019-08-14 Regents of the University of Minnesota COMPOSITIONS AND METHODS FOR CHIMERIC EMBRYO-ASSISTED ORGAN PRODUCTION
CN108125943A (zh) 2018-01-17 2018-06-08 云南省第二人民医院 前胡醇当归脂作为制备抗动脉粥样硬化药物的应用

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