JP2018523999A5 - - Google Patents

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Publication number
JP2018523999A5
JP2018523999A5 JP2017568252A JP2017568252A JP2018523999A5 JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5 JP 2017568252 A JP2017568252 A JP 2017568252A JP 2017568252 A JP2017568252 A JP 2017568252A JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5
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JP
Japan
Prior art keywords
gene
handii
tbx5
nkx2
human
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Pending
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JP2017568252A
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English (en)
Japanese (ja)
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JP2018523999A (ja
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Priority claimed from PCT/US2016/040431 external-priority patent/WO2017004388A1/en
Publication of JP2018523999A publication Critical patent/JP2018523999A/ja
Publication of JP2018523999A5 publication Critical patent/JP2018523999A5/ja
Pending legal-status Critical Current

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JP2017568252A 2015-06-30 2016-06-30 ヒト化心筋 Pending JP2018523999A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562187040P 2015-06-30 2015-06-30
US62/187,040 2015-06-30
PCT/US2016/040431 WO2017004388A1 (en) 2015-06-30 2016-06-30 Humanized heart muscle

Publications (2)

Publication Number Publication Date
JP2018523999A JP2018523999A (ja) 2018-08-30
JP2018523999A5 true JP2018523999A5 (https=) 2019-08-08

Family

ID=57609529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017568252A Pending JP2018523999A (ja) 2015-06-30 2016-06-30 ヒト化心筋

Country Status (13)

Country Link
US (2) US10897880B2 (https=)
EP (1) EP3316899A4 (https=)
JP (1) JP2018523999A (https=)
KR (1) KR20180021135A (https=)
CN (1) CN108472318A (https=)
AU (1) AU2016288671A1 (https=)
BR (1) BR112017028608A2 (https=)
CA (1) CA2991056A1 (https=)
CO (1) CO2018000859A2 (https=)
IL (1) IL256544A (https=)
MX (1) MX2018000071A (https=)
RU (1) RU2018103234A (https=)
WO (1) WO2017004388A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2978457A1 (en) 2015-03-03 2016-09-09 Regents Of The University Of Minnesota Etv2 and uses thereof
RU2018103093A (ru) 2015-06-30 2019-07-31 Реджентс Оф Зэ Юниверсити Оф Миннесота Гуманизированная скелетная мышца
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2242666A1 (en) * 1996-01-09 1997-07-17 The Regents Of The University Of California Ungulate embryonic stem-like cells, methods of making and using the cells to produce transgenic ungulates
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
CN1241210A (zh) * 1996-10-11 2000-01-12 得克萨斯农业及机械体系综合大学 产生原生殖细胞和转基因动物物种的方法
EP1449431A4 (en) 2001-10-24 2007-11-28 Chugai Pharmaceutical Co Ltd SGRF-TRANSGENIC NON-MENTAL ANIMAL
US20040133931A1 (en) 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
AU2003213813A1 (en) 2002-03-22 2003-10-13 St. Jude Children's Research Hospital Improved method for generating genetically modified animals
JP2006506968A (ja) 2002-07-03 2006-03-02 メルク エンド カムパニー インコーポレーテッド アグーチ関連蛋白質欠損細胞、非ヒトトランスジェニック動物及びエネルギー代謝を調節する化合物の選択方法
GB2398784B (en) 2003-02-26 2005-07-27 Babraham Inst Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal
WO2006014551A2 (en) 2004-07-06 2006-02-09 Michigan State University In vivo methods for effecting tissue specific differentiation of embryonic stem cells
DK2118271T3 (en) 2007-01-11 2018-07-23 Univ Pittsburgh Commonwealth Sys Higher Education MUSCLE DERIVATIVE CELLS FOR THE TREATMENT OF URINARY DISEASES AND PROCEDURES FOR THEIR PREPARATION AND USE
US20100107263A1 (en) 2007-01-20 2010-04-29 Boehringer Ingelheim International Gmbh & Co., Kg C-reactive protein (crp) knockout mouse
JPWO2008102602A1 (ja) 2007-02-22 2010-05-27 国立大学法人 東京大学 Blastocystcomplementationを利用した臓器再生法
WO2009104794A1 (ja) 2008-02-22 2009-08-27 国立大学法人 東京大学 遺伝子改変による致死性表現型を持つ動物の繁殖用ファウンダー動物作製法
GB2475656B (en) 2008-08-22 2013-04-24 Univ Tokyo Organ regeneration method utilizing ips cell and blastocyst complementation
US20120207744A1 (en) 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
AU2010251151B2 (en) * 2009-05-20 2015-08-20 Cardio3 Biosciences S.A. Pharmaceutical Composition for the Treatment of Heart Diseases
KR102068107B1 (ko) 2011-04-27 2020-01-20 아미리스 인코퍼레이티드 게놈 변형 방법
KR101970634B1 (ko) 2011-06-02 2019-04-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 생체외 조직 배양 시스템을 위한 방법 및 용도
WO2013073246A1 (en) 2011-11-18 2013-05-23 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
IL221187A (en) 2012-07-30 2017-01-31 Adom Advanced Optical Tech Ltd A system to perform optical tomography in two 2D beams
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
US11377639B2 (en) * 2013-11-15 2022-07-05 Wisconsin Alumni Research Foundation Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
WO2015168125A1 (en) 2014-04-28 2015-11-05 Recombinetics, Inc. Multiplex gene editing in swine
CA2978457A1 (en) 2015-03-03 2016-09-09 Regents Of The University Of Minnesota Etv2 and uses thereof
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado
RU2018103093A (ru) 2015-06-30 2019-07-31 Реджентс Оф Зэ Юниверсити Оф Миннесота Гуманизированная скелетная мышца
CN108697067A (zh) 2015-10-27 2018-10-23 明尼苏达大学评议会 嵌合胚胎-辅助的器官制备的组合物和方法
CN108125943A (zh) 2018-01-17 2018-06-08 云南省第二人民医院 前胡醇当归脂作为制备抗动脉粥样硬化药物的应用

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