EP3367785A4 - Compositions and methods for chimeric embryo-assisted organ production - Google Patents
Compositions and methods for chimeric embryo-assisted organ production Download PDFInfo
- Publication number
- EP3367785A4 EP3367785A4 EP16860830.5A EP16860830A EP3367785A4 EP 3367785 A4 EP3367785 A4 EP 3367785A4 EP 16860830 A EP16860830 A EP 16860830A EP 3367785 A4 EP3367785 A4 EP 3367785A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- assisted
- compositions
- methods
- chimeric embryo
- organ production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000001161 mammalian embryo Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 210000000056 organ Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562247117P | 2015-10-27 | 2015-10-27 | |
US201562247092P | 2015-10-27 | 2015-10-27 | |
US201562246929P | 2015-10-27 | 2015-10-27 | |
US201562247096P | 2015-10-27 | 2015-10-27 | |
US201562246947P | 2015-10-27 | 2015-10-27 | |
US201562246927P | 2015-10-27 | 2015-10-27 | |
US201562247122P | 2015-10-27 | 2015-10-27 | |
US201562247118P | 2015-10-27 | 2015-10-27 | |
US201562246926P | 2015-10-27 | 2015-10-27 | |
US201562247115P | 2015-10-27 | 2015-10-27 | |
PCT/US2016/059206 WO2017075276A2 (en) | 2015-10-27 | 2016-10-27 | Compositions and methods for chimeric embryo-assisted organ production |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3367785A2 EP3367785A2 (en) | 2018-09-05 |
EP3367785A4 true EP3367785A4 (en) | 2019-08-14 |
Family
ID=58631806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16860830.5A Withdrawn EP3367785A4 (en) | 2015-10-27 | 2016-10-27 | Compositions and methods for chimeric embryo-assisted organ production |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP3367785A4 (en) |
JP (1) | JP2019502400A (en) |
KR (1) | KR20180100303A (en) |
CN (1) | CN108697067A (en) |
AU (1) | AU2016344152A1 (en) |
CA (1) | CA3003652A1 (en) |
WO (1) | WO2017075276A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102684690B1 (en) | 2015-03-03 | 2024-07-15 | 리젠츠 오브 더 유니버시티 오브 미네소타 | ETV2 and its uses |
RU2018103234A (en) | 2015-06-30 | 2019-07-31 | Реджентс Оф Зэ Юниверсити Оф Миннесота | HUMANIZED HEART MUSCLE |
CN108135943A (en) * | 2015-06-30 | 2018-06-08 | 明尼苏达大学校董会 | The skeletal muscle of humanization |
MX2018015194A (en) * | 2016-06-14 | 2020-01-20 | Riddle Inst For Regenerative Medicine | Organ regeneration method using somatic cell nuclear transfer (scnt) cell and blastocyst complementation. |
WO2019033053A1 (en) | 2017-08-11 | 2019-02-14 | Recombinetics, Inc. | Inducible disease models methods of making them and use in tissue complementation |
CN109258575B (en) * | 2018-12-10 | 2021-07-06 | 广东工业大学 | Incubation method of frog animal embryo |
US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
US11859213B2 (en) | 2019-05-16 | 2024-01-02 | Regents Of The University Of Minnesota | Development of superior chimerism by hiPSC engineering and embryo aggregation |
WO2020263880A1 (en) * | 2019-06-26 | 2020-12-30 | The Regents Of The University Of California | SIRPalpha-SILENCED NATURAL KILLER (NK) CELLS |
US11576889B2 (en) | 2019-09-23 | 2023-02-14 | The Board Of Regents Of The University Of Texas System | Methods of identifying and treating patients with HIF-2 inhibitor resistance |
CN116433652B (en) * | 2023-05-11 | 2024-02-23 | 中南大学 | Method, processor and device for determining pregnancy outcome of embryo transfer |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100122360A1 (en) * | 2007-02-22 | 2010-05-13 | The University Of Tokyo | Organ regeneration method utilizing blastocyst complementation |
-
2016
- 2016-10-27 AU AU2016344152A patent/AU2016344152A1/en not_active Abandoned
- 2016-10-27 CA CA3003652A patent/CA3003652A1/en not_active Abandoned
- 2016-10-27 JP JP2018542691A patent/JP2019502400A/en active Pending
- 2016-10-27 KR KR1020187014498A patent/KR20180100303A/en unknown
- 2016-10-27 CN CN201680074878.7A patent/CN108697067A/en active Pending
- 2016-10-27 EP EP16860830.5A patent/EP3367785A4/en not_active Withdrawn
- 2016-10-27 WO PCT/US2016/059206 patent/WO2017075276A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100122360A1 (en) * | 2007-02-22 | 2010-05-13 | The University Of Tokyo | Organ regeneration method utilizing blastocyst complementation |
Non-Patent Citations (4)
Title |
---|
MADHUSUDANA GIRIJA SANAL: "Future of liver transplantation: Non-human primates for patient-specific organs from induced pluripotent stem cells", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 17, no. 32, 2011, CN, pages 3684, XP055602899, ISSN: 1007-9327, DOI: 10.3748/wjg.v17.i32.3684 * |
PREETHI SWAMINATHAN: "Human Stem Cell Complementation in PITX3 Null Porcine Blastocysts: Lens Development", December 2014 (2014-12-01), XP055493473, Retrieved from the Internet <URL:https://conservancy.umn.edu/bitstream/handle/11299/185108/Swaminathan_umn_0130M_15713.pdf?sequence=1> [retrieved on 20180718] * |
XIANLONG WANG ET AL: "Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs", SCIENTIFIC REPORTS, vol. 5, no. 1, 21 August 2015 (2015-08-21), XP055551206, DOI: 10.1038/srep13348 * |
YUYU NIU ET AL: "Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos", CELL, vol. 156, no. 4, February 2014 (2014-02-01), AMSTERDAM, NL, pages 836 - 843, XP055422516, ISSN: 0092-8674, DOI: 10.1016/j.cell.2014.01.027 * |
Also Published As
Publication number | Publication date |
---|---|
EP3367785A2 (en) | 2018-09-05 |
JP2019502400A (en) | 2019-01-31 |
WO2017075276A2 (en) | 2017-05-04 |
CA3003652A1 (en) | 2017-05-04 |
CN108697067A (en) | 2018-10-23 |
KR20180100303A (en) | 2018-09-10 |
AU2016344152A1 (en) | 2018-05-24 |
WO2017075276A3 (en) | 2017-06-01 |
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Legal Events
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: PANOSKALTSIS-MORTARI, ANGELA Inventor name: PARR, ANN Inventor name: ASAKURA, ATSUSHI Inventor name: KOYANO-NAKAGAWA, NAOKO Inventor name: O'BRIEN, TIMOTHY Inventor name: GARRY, MARY, G. Inventor name: DUTTON, JAMES Inventor name: CHEERAN, MAXIN Inventor name: CARLSON, DANIEL, F. Inventor name: LOW, WALTER Inventor name: FAHRENKRUG, SCOTT, C. Inventor name: GARRY, DANIEL, J. Inventor name: ARAVALLI, RAJ Inventor name: GRAHAM, MELANIE Inventor name: STEER, CLIFFORD Inventor name: LI, LING Inventor name: TOLAR, JAKUP |
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DAV | Request for validation of the european patent (deleted) | ||
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: CHEERAN, MAXIM C. Inventor name: PARR, ANN Inventor name: STEER, CLIFFORD Inventor name: TOLAR, JAKUB Inventor name: O'BRIEN, TIMOTHY Inventor name: GARRY, DANIEL, J. Inventor name: KOYANO-NAKAGAWA, NAOKO Inventor name: DUTTON, JAMES Inventor name: CARLSON, DANIEL, F. Inventor name: PANOSKALTSIS-MORTARI, ANGELA Inventor name: GARRY, MARY, G. Inventor name: LOW, WALTER Inventor name: ASAKURA, ATSUSHI Inventor name: ARAVALLI, RAJ Inventor name: LI, LING Inventor name: FAHRENKRUG, SCOTT, C. Inventor name: GRAHAM, MELANIE |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/90 20060101ALI20190410BHEP Ipc: A01K 67/027 20060101AFI20190410BHEP Ipc: A01N 1/02 20060101ALI20190410BHEP Ipc: C12N 15/85 20060101ALI20190410BHEP Ipc: A61D 19/04 20060101ALI20190410BHEP |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20190712 |
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Ipc: C12N 15/85 20060101ALI20190708BHEP Ipc: A01K 67/027 20060101AFI20190708BHEP Ipc: C12N 15/90 20060101ALI20190708BHEP Ipc: A61D 19/04 20060101ALI20190708BHEP Ipc: A01N 1/02 20060101ALI20190708BHEP |
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Inventor name: O'BRIEN, TIMOTHY Inventor name: ARAVALLI, RAJ Inventor name: FAHRENKRUG, SCOTT, C. Inventor name: PANOSKALTSIS-MORTARI, ANGELA Inventor name: PARR, ANN Inventor name: KOYANO, NAOKO Inventor name: GARRY, MARY, G. Inventor name: GARRY, DANIEL, J. Inventor name: CHEERAN, MAXIM C. Inventor name: LI, LING Inventor name: ASAKURA, ATSUSHI Inventor name: LOW, WALTER Inventor name: GRAHAM, MELANIE Inventor name: DUTTON, JAMES Inventor name: CARLSON, DANIEL, F. Inventor name: STEER, CLIFFORD Inventor name: TOLAR, JAKUB |
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