JP2018523999A5 - - Google Patents

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Publication number
JP2018523999A5
JP2018523999A5 JP2017568252A JP2017568252A JP2018523999A5 JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5 JP 2017568252 A JP2017568252 A JP 2017568252A JP 2017568252 A JP2017568252 A JP 2017568252A JP 2018523999 A5 JP2018523999 A5 JP 2018523999A5
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JP
Japan
Prior art keywords
gene
handii
tbx5
nkx2
human
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Pending
Application number
JP2017568252A
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English (en)
Japanese (ja)
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JP2018523999A (ja
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Publication date
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Priority claimed from PCT/US2016/040431 external-priority patent/WO2017004388A1/en
Publication of JP2018523999A publication Critical patent/JP2018523999A/ja
Publication of JP2018523999A5 publication Critical patent/JP2018523999A5/ja
Pending legal-status Critical Current

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JP2017568252A 2015-06-30 2016-06-30 ヒト化心筋 Pending JP2018523999A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562187040P 2015-06-30 2015-06-30
US62/187,040 2015-06-30
PCT/US2016/040431 WO2017004388A1 (en) 2015-06-30 2016-06-30 Humanized heart muscle

Publications (2)

Publication Number Publication Date
JP2018523999A JP2018523999A (ja) 2018-08-30
JP2018523999A5 true JP2018523999A5 (OSRAM) 2019-08-08

Family

ID=57609529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017568252A Pending JP2018523999A (ja) 2015-06-30 2016-06-30 ヒト化心筋

Country Status (13)

Country Link
US (2) US10897880B2 (OSRAM)
EP (1) EP3316899A4 (OSRAM)
JP (1) JP2018523999A (OSRAM)
KR (1) KR20180021135A (OSRAM)
CN (1) CN108472318A (OSRAM)
AU (1) AU2016288671A1 (OSRAM)
BR (1) BR112017028608A2 (OSRAM)
CA (1) CA2991056A1 (OSRAM)
CO (1) CO2018000859A2 (OSRAM)
IL (1) IL256544A (OSRAM)
MX (1) MX2018000071A (OSRAM)
RU (1) RU2018103234A (OSRAM)
WO (1) WO2017004388A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108024522A (zh) 2015-03-03 2018-05-11 明尼苏达大学董事会 Etv2及其用途
MX2018000273A (es) 2015-06-30 2018-03-08 Univ Minnesota Musculo esqueletico humanizado.
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU721375B2 (en) * 1996-01-09 2000-06-29 Regents Of The University Of California, The Porcine embryonic stem-like cells, methods of making and using the cells to produce transgenic pigs
US5994619A (en) * 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
CN1241210A (zh) * 1996-10-11 2000-01-12 得克萨斯农业及机械体系综合大学 产生原生殖细胞和转基因动物物种的方法
WO2003034818A1 (en) 2001-10-24 2003-05-01 Chugai Seiyaku Kabushiki Kaisha Sgrf genetically modified nonhuman animal
US20040133931A1 (en) 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
WO2003081990A2 (en) 2002-03-22 2003-10-09 St. Jude Children's Research Hospital Improved method for generating genetically modified animals
WO2004004447A2 (en) 2002-07-03 2004-01-15 Merck & Co., Inc. Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
GB2398784B (en) 2003-02-26 2005-07-27 Babraham Inst Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal
WO2006014551A2 (en) 2004-07-06 2006-02-09 Michigan State University In vivo methods for effecting tissue specific differentiation of embryonic stem cells
WO2008086040A1 (en) 2007-01-11 2008-07-17 University Of Pittsburgh Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same
CA2675100A1 (en) 2007-01-20 2008-07-24 Boehringer Ingelheim International Gmbh C-reactive protein (crp) knockout mouse
CN101679950A (zh) 2007-02-22 2010-03-24 国立大学法人东京大学 利用胚泡互补的器官再生法
EP2258166A4 (en) 2008-02-22 2013-04-03 Univ Tokyo METHOD FOR PRODUCING GROUNDS FOR REPRODUCATIVE ANIMALS WITH LETAL PHENOTYPE CREATED BY GENODIMODIFICATION
US20110258715A1 (en) 2008-08-22 2011-10-20 The University Of Tokyo ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION
US20120207744A1 (en) 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
SG175880A1 (en) * 2009-05-20 2011-12-29 Cardio3 Biosciences Sa Parmaceutical composition for the treatment of heart diseases.
WO2012149470A1 (en) 2011-04-27 2012-11-01 Amyris, Inc. Methods for genomic modification
SG10201805199RA (en) 2011-06-02 2018-07-30 Harvard College Methods and Uses for Ex Vivo Tissue Culture Systems
WO2013073246A1 (en) 2011-11-18 2013-05-23 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
IL221187A (en) 2012-07-30 2017-01-31 Adom Advanced Optical Tech Ltd A system to perform optical tomography in two 2D beams
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
US11377639B2 (en) * 2013-11-15 2022-07-05 Wisconsin Alumni Research Foundation Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
US20160029604A1 (en) 2014-04-28 2016-02-04 Recombinetics, Inc. Multiplex gene editing
CN108024522A (zh) 2015-03-03 2018-05-11 明尼苏达大学董事会 Etv2及其用途
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado
MX2018000273A (es) 2015-06-30 2018-03-08 Univ Minnesota Musculo esqueletico humanizado.
EP3367785A4 (en) 2015-10-27 2019-08-14 Regents of the University of Minnesota COMPOSITIONS AND METHODS FOR CHIMERIC EMBRYO-ASSISTED ORGAN PRODUCTION
CN108125943A (zh) 2018-01-17 2018-06-08 云南省第二人民医院 前胡醇当归脂作为制备抗动脉粥样硬化药物的应用

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