JP2018519259A5 - - Google Patents

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Publication number
JP2018519259A5
JP2018519259A5 JP2017557440A JP2017557440A JP2018519259A5 JP 2018519259 A5 JP2018519259 A5 JP 2018519259A5 JP 2017557440 A JP2017557440 A JP 2017557440A JP 2017557440 A JP2017557440 A JP 2017557440A JP 2018519259 A5 JP2018519259 A5 JP 2018519259A5
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JP
Japan
Prior art keywords
fluorobenzyl
pyrazolo
diamino
pyridin
carbamate
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JP2017557440A
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English (en)
Japanese (ja)
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JP2018519259A (ja
JP6748113B2 (ja
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Priority claimed from PCT/EP2016/059734 external-priority patent/WO2016177660A1/en
Publication of JP2018519259A publication Critical patent/JP2018519259A/ja
Publication of JP2018519259A5 publication Critical patent/JP2018519259A5/ja
Application granted granted Critical
Publication of JP6748113B2 publication Critical patent/JP6748113B2/ja
Expired - Fee Related legal-status Critical Current
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JP2017557440A 2015-05-06 2016-05-02 全身性硬化症(SSc)に付随する指潰瘍(DU)を治療するための単独のまたはPDE5阻害剤と組み合わせたsGC刺激剤、sGC活性化剤の使用 Expired - Fee Related JP6748113B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15166516.3 2015-05-06
EP15166516 2015-05-06
PCT/EP2016/059734 WO2016177660A1 (en) 2015-05-06 2016-05-02 The use of sgc stimulators, sgc activators, alone and combinations with pde5 inhibitors for the treatment of digital ulcers (du) concomitant to systemic sclerosis (ssc)

Publications (3)

Publication Number Publication Date
JP2018519259A JP2018519259A (ja) 2018-07-19
JP2018519259A5 true JP2018519259A5 (https=) 2019-04-18
JP6748113B2 JP6748113B2 (ja) 2020-08-26

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ID=53040455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017557440A Expired - Fee Related JP6748113B2 (ja) 2015-05-06 2016-05-02 全身性硬化症(SSc)に付随する指潰瘍(DU)を治療するための単独のまたはPDE5阻害剤と組み合わせたsGC刺激剤、sGC活性化剤の使用

Country Status (17)

Country Link
US (1) US20180169095A1 (https=)
EP (1) EP3291811B1 (https=)
JP (1) JP6748113B2 (https=)
KR (1) KR20180002657A (https=)
CN (1) CN107580495A (https=)
AU (1) AU2016258847A1 (https=)
BR (1) BR112017023855A2 (https=)
CA (1) CA2984983A1 (https=)
CL (1) CL2017002765A1 (https=)
EA (1) EA201792346A1 (https=)
HK (1) HK1243645A1 (https=)
IL (1) IL255214A0 (https=)
MX (1) MX2017014057A (https=)
PH (1) PH12017501980A1 (https=)
TN (1) TN2017000465A1 (https=)
WO (1) WO2016177660A1 (https=)
ZA (1) ZA201708248B (https=)

Families Citing this family (7)

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WO2017015760A1 (en) 2015-07-28 2017-02-02 Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et Humaines, S.E.C. A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin
EP3574905A1 (en) 2018-05-30 2019-12-04 Adverio Pharma GmbH Method of identifying a subgroup of patients suffering from dcssc which benefits from a treatment with sgc stimulators and sgc activators in a higher degree than a control group
KR20210150495A (ko) 2019-04-10 2021-12-10 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 심혈관 기능장애의 성별-의존적 치료를 위한 방법 및 재료
JP2023541601A (ja) 2020-09-10 2023-10-03 プレシリックス・ナームローゼ・ベンノートシヤープ Fapに対する抗体フラグメント
WO2023203135A1 (en) 2022-04-22 2023-10-26 Precirix N.V. Improved radiolabelled antibody
AU2023264245A1 (en) 2022-05-02 2024-12-19 Precirix N.V. Pre-targeting
CN120225203A (zh) 2022-11-04 2025-06-27 勃林格殷格翰国际有限公司 用于治疗系统性硬化症的可溶性鸟苷酸环化酶活化剂

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