JP2018515510A5 - - Google Patents
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- Publication number
- JP2018515510A5 JP2018515510A5 JP2017558467A JP2017558467A JP2018515510A5 JP 2018515510 A5 JP2018515510 A5 JP 2018515510A5 JP 2017558467 A JP2017558467 A JP 2017558467A JP 2017558467 A JP2017558467 A JP 2017558467A JP 2018515510 A5 JP2018515510 A5 JP 2018515510A5
- Authority
- JP
- Japan
- Prior art keywords
- configuration
- subject
- heart failure
- incorporated
- polynucleotide vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 10
- 241000702421 Dependoparvovirus Species 0.000 description 3
- 102000040430 polynucleotide Human genes 0.000 description 3
- 108091033319 polynucleotide Proteins 0.000 description 3
- 239000002157 polynucleotide Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 206010019280 Heart failures Diseases 0.000 description 2
- 101800001904 NT-proBNP Proteins 0.000 description 2
- 102400001263 NT-proBNP Human genes 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 102000014413 Neuregulin Human genes 0.000 description 1
- 108050003475 Neuregulin Proteins 0.000 description 1
- 208000019269 advanced heart failure Diseases 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 210000002064 heart cell Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510232415.6A CN106177992A (zh) | 2015-05-08 | 2015-05-08 | cMLCK基因导入 |
| CNCN201510232415.6 | 2015-05-08 | ||
| PCT/CN2016/085699 WO2016180377A1 (zh) | 2015-05-08 | 2016-06-14 | cMLCK基因导入 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018515510A JP2018515510A (ja) | 2018-06-14 |
| JP2018515510A5 true JP2018515510A5 (enExample) | 2019-07-11 |
Family
ID=57247711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017558467A Pending JP2018515510A (ja) | 2015-05-08 | 2016-06-14 | cMLCK遺伝子導入 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180133291A1 (enExample) |
| EP (1) | EP3295959A4 (enExample) |
| JP (1) | JP2018515510A (enExample) |
| KR (1) | KR20190008511A (enExample) |
| CN (3) | CN111388682A (enExample) |
| AU (1) | AU2016260473A1 (enExample) |
| BR (1) | BR112017024065A2 (enExample) |
| CA (1) | CA2985396A1 (enExample) |
| RU (1) | RU2017142779A (enExample) |
| WO (1) | WO2016180377A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
| RU2650635C2 (ru) | 2012-10-08 | 2018-04-16 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Композиции и способы лечения сердечной недостаточности у пациентов с диабетом |
| CN111388682A (zh) * | 2015-05-08 | 2020-07-10 | 上海泽生科技开发股份有限公司 | cMLCK基因导入 |
| CN115838437A (zh) * | 2022-11-04 | 2023-03-24 | 广州达安基因股份有限公司 | 人NT-proBNP融合蛋白及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7375185B2 (en) * | 2000-09-12 | 2008-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | Cardiac myosin light chain kinase polypeptide, encoding nucleic acid, and methods of use |
| US9580515B2 (en) * | 2006-08-21 | 2017-02-28 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neukinase, a downstream protein of neuregulin |
| JP2009242388A (ja) * | 2008-03-14 | 2009-10-22 | National Cardiovascular Center | 心臓特異的キナーゼの心不全診断および治療への応用 |
| CN102416184A (zh) * | 2011-12-08 | 2012-04-18 | 哈尔滨医科大学 | microRNA-1的反义锁核苷酸序列在制备预防或治疗心肌梗死后心衰药物中的应用 |
| CN111388682A (zh) * | 2015-05-08 | 2020-07-10 | 上海泽生科技开发股份有限公司 | cMLCK基因导入 |
-
2015
- 2015-05-08 CN CN202010310166.9A patent/CN111388682A/zh active Pending
- 2015-05-08 CN CN201510232415.6A patent/CN106177992A/zh active Pending
-
2016
- 2016-06-14 BR BR112017024065-3A patent/BR112017024065A2/pt not_active Application Discontinuation
- 2016-06-14 KR KR1020177032419A patent/KR20190008511A/ko not_active Withdrawn
- 2016-06-14 US US15/572,467 patent/US20180133291A1/en not_active Abandoned
- 2016-06-14 EP EP16792227.7A patent/EP3295959A4/en not_active Withdrawn
- 2016-06-14 AU AU2016260473A patent/AU2016260473A1/en not_active Abandoned
- 2016-06-14 CN CN201680025125.7A patent/CN107735109A/zh active Pending
- 2016-06-14 WO PCT/CN2016/085699 patent/WO2016180377A1/zh not_active Ceased
- 2016-06-14 JP JP2017558467A patent/JP2018515510A/ja active Pending
- 2016-06-14 RU RU2017142779A patent/RU2017142779A/ru not_active Application Discontinuation
- 2016-06-14 CA CA2985396A patent/CA2985396A1/en not_active Abandoned
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