BR112017024065A2 - método para tratar insuficiência cardíaca avançada em um indivíduo humano - Google Patents
método para tratar insuficiência cardíaca avançada em um indivíduo humanoInfo
- Publication number
- BR112017024065A2 BR112017024065A2 BR112017024065-3A BR112017024065A BR112017024065A2 BR 112017024065 A2 BR112017024065 A2 BR 112017024065A2 BR 112017024065 A BR112017024065 A BR 112017024065A BR 112017024065 A2 BR112017024065 A2 BR 112017024065A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- cmlck
- protein
- polynucleotide vector
- methods
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 102000040430 polynucleotide Human genes 0.000 abstract 4
- 108091033319 polynucleotide Proteins 0.000 abstract 4
- 239000002157 polynucleotide Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 208000019269 advanced heart failure Diseases 0.000 abstract 2
- 210000002064 heart cell Anatomy 0.000 abstract 2
- 230000002861 ventricular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11018—Myosin-light-chain kinase (2.7.11.18)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510232415.6A CN106177992A (zh) | 2015-05-08 | 2015-05-08 | cMLCK基因导入 |
| CNCN201510232415.6 | 2015-05-08 | ||
| PCT/CN2016/085699 WO2016180377A1 (zh) | 2015-05-08 | 2016-06-14 | cMLCK基因导入 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017024065A2 true BR112017024065A2 (pt) | 2018-08-07 |
Family
ID=57247711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017024065-3A BR112017024065A2 (pt) | 2015-05-08 | 2016-06-14 | método para tratar insuficiência cardíaca avançada em um indivíduo humano |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20180133291A1 (enExample) |
| EP (1) | EP3295959A4 (enExample) |
| JP (1) | JP2018515510A (enExample) |
| KR (1) | KR20190008511A (enExample) |
| CN (3) | CN106177992A (enExample) |
| AU (1) | AU2016260473A1 (enExample) |
| BR (1) | BR112017024065A2 (enExample) |
| CA (1) | CA2985396A1 (enExample) |
| RU (1) | RU2017142779A (enExample) |
| WO (1) | WO2016180377A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| CN109276705B (zh) | 2012-10-08 | 2023-10-20 | 上海泽生科技开发股份有限公司 | 治疗糖尿病患者心力衰竭的组份和方法 |
| CN106177992A (zh) * | 2015-05-08 | 2016-12-07 | 上海泽生科技开发有限公司 | cMLCK基因导入 |
| CN115838437A (zh) * | 2022-11-04 | 2023-03-24 | 广州达安基因股份有限公司 | 人NT-proBNP融合蛋白及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002024889A2 (en) * | 2000-09-12 | 2002-03-28 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Optimized cardiac contraction through differential phosphorylation of myosin |
| US9580515B2 (en) * | 2006-08-21 | 2017-02-28 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neukinase, a downstream protein of neuregulin |
| JP2009242388A (ja) * | 2008-03-14 | 2009-10-22 | National Cardiovascular Center | 心臓特異的キナーゼの心不全診断および治療への応用 |
| CN102416184A (zh) * | 2011-12-08 | 2012-04-18 | 哈尔滨医科大学 | microRNA-1的反义锁核苷酸序列在制备预防或治疗心肌梗死后心衰药物中的应用 |
| CN106177992A (zh) * | 2015-05-08 | 2016-12-07 | 上海泽生科技开发有限公司 | cMLCK基因导入 |
-
2015
- 2015-05-08 CN CN201510232415.6A patent/CN106177992A/zh active Pending
- 2015-05-08 CN CN202010310166.9A patent/CN111388682A/zh active Pending
-
2016
- 2016-06-14 RU RU2017142779A patent/RU2017142779A/ru not_active Application Discontinuation
- 2016-06-14 AU AU2016260473A patent/AU2016260473A1/en not_active Abandoned
- 2016-06-14 CN CN201680025125.7A patent/CN107735109A/zh active Pending
- 2016-06-14 CA CA2985396A patent/CA2985396A1/en not_active Abandoned
- 2016-06-14 WO PCT/CN2016/085699 patent/WO2016180377A1/zh not_active Ceased
- 2016-06-14 JP JP2017558467A patent/JP2018515510A/ja active Pending
- 2016-06-14 EP EP16792227.7A patent/EP3295959A4/en not_active Withdrawn
- 2016-06-14 US US15/572,467 patent/US20180133291A1/en not_active Abandoned
- 2016-06-14 BR BR112017024065-3A patent/BR112017024065A2/pt not_active Application Discontinuation
- 2016-06-14 KR KR1020177032419A patent/KR20190008511A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2985396A1 (en) | 2016-11-17 |
| RU2017142779A (ru) | 2019-06-10 |
| CN107735109A (zh) | 2018-02-23 |
| KR20190008511A (ko) | 2019-01-24 |
| CN106177992A (zh) | 2016-12-07 |
| US20180133291A1 (en) | 2018-05-17 |
| EP3295959A1 (en) | 2018-03-21 |
| AU2016260473A1 (en) | 2017-12-21 |
| CN111388682A (zh) | 2020-07-10 |
| WO2016180377A1 (zh) | 2016-11-17 |
| EP3295959A4 (en) | 2019-01-02 |
| RU2017142779A3 (enExample) | 2019-12-03 |
| JP2018515510A (ja) | 2018-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notice of approval relating to section 229 industrial property law | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |