BR112017010028A2 - ?métodos e composições para aumentar a pigmentação da pele? - Google Patents

?métodos e composições para aumentar a pigmentação da pele?

Info

Publication number
BR112017010028A2
BR112017010028A2 BR112017010028A BR112017010028A BR112017010028A2 BR 112017010028 A2 BR112017010028 A2 BR 112017010028A2 BR 112017010028 A BR112017010028 A BR 112017010028A BR 112017010028 A BR112017010028 A BR 112017010028A BR 112017010028 A2 BR112017010028 A2 BR 112017010028A2
Authority
BR
Brazil
Prior art keywords
pigmentation
methods
compositions
modifying
skin pigmentation
Prior art date
Application number
BR112017010028A
Other languages
English (en)
Other versions
BR112017010028B1 (pt
Inventor
Erich Fisher David
Maria Roider Elisabeth
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of BR112017010028A2 publication Critical patent/BR112017010028A2/pt
Publication of BR112017010028B1 publication Critical patent/BR112017010028B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

métodos e composições úteis para melhorar pigmentação, tal como pigmentação de pele, olho e/ou cabelo compreendendo administrar, por exemplo, um inibidor de nnt ou um agente que modifica o estado redox em um melanócito são descritos aqui. os métodos e composições fornecidos aqui são baseados na constatação de que a modificação do estado redução/oxidação de uma célula (por exemplo, um melanócito) pela inibição de transidrogenase de nucleotídeo de nicotinamida (nnt) melhora a pigmentação da pele. assim, modular a pigmentação cutânea através da modificação de tal mecanismo específico de sistema redox pode ser utilizado para prevenir a formação de melanoma e para tratar distúrbios de pigmentação.
BR112017010028-2A 2014-11-14 2015-11-16 métodos e composições para aumentar a pigmentação da pele BR112017010028B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462079772P 2014-11-14 2014-11-14
US62/079,772 2014-11-14
PCT/US2015/060837 WO2016077817A1 (en) 2014-11-14 2015-11-16 Methods and compositions for enhancing skin pigmentation

Publications (2)

Publication Number Publication Date
BR112017010028A2 true BR112017010028A2 (pt) 2018-01-02
BR112017010028B1 BR112017010028B1 (pt) 2021-05-25

Family

ID=55955187

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017010028-2A BR112017010028B1 (pt) 2014-11-14 2015-11-16 métodos e composições para aumentar a pigmentação da pele

Country Status (5)

Country Link
US (1) US9883996B2 (pt)
EP (1) EP3218507B1 (pt)
AU (1) AU2015346022B2 (pt)
BR (1) BR112017010028B1 (pt)
WO (1) WO2016077817A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180025701A (ko) * 2016-09-01 2018-03-09 (주)아모레퍼시픽 특정 siRNA을 포함하는 멜라닌 증진용 조성물
CN110669937B (zh) * 2019-11-07 2021-06-22 华东理工大学 一种利用谷胱甘肽提高废弃锂电池中金属生物浸出率的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2180153A (en) 1985-09-10 1987-03-25 Rory Ltd Compositions containing acetylcysteine
US5700450A (en) * 1988-03-30 1997-12-23 The Trustees Of Boston University Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof
US5296500A (en) 1991-08-30 1994-03-22 The Procter & Gamble Company Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
MX9700038A (es) 1994-06-23 1997-04-30 Procter & Gamble Composiciones topicas que comprenden n-acetil-l- cisteina.
JP2001525353A (ja) 1997-12-08 2001-12-11 アリゾナ ボード オブ リージェンツ 長時間作用する、化学的に耐性な皮膚エモリエント剤、モイスチャライザー、および強化剤
US20030229141A1 (en) 1999-01-08 2003-12-11 Yu Ruey J. N-acetyl cysteine and its topical use
US6159485A (en) 1999-01-08 2000-12-12 Yugenic Limited Partnership N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use
US7214655B2 (en) * 2001-05-21 2007-05-08 Johnson & Johnson Consumer Companies, Inc. Peptides and the use thereof in darkening the skin
WO2014015118A1 (en) * 2012-07-20 2014-01-23 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the diagnosis and treatment of cellular proliferative disorders
EP2740484A1 (en) * 2012-12-05 2014-06-11 Lipotec, S.A. Compounds useful in the treatment and/or care of the skin, hair and/or muccous membranes and their cosmetic or pharmaceutical compositions

Also Published As

Publication number Publication date
EP3218507A1 (en) 2017-09-20
EP3218507B1 (en) 2020-01-08
US9883996B2 (en) 2018-02-06
WO2016077817A1 (en) 2016-05-19
AU2015346022A1 (en) 2017-05-25
US20160136070A1 (en) 2016-05-19
BR112017010028B1 (pt) 2021-05-25
AU2015346022B2 (en) 2020-01-02
EP3218507A4 (en) 2018-04-18

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C12P 19/36

Ipc: A61K 8/40 (2006.01), A61K 8/35 (2006.01), A61K 8/4

B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/11/2015, OBSERVADAS AS CONDICOES LEGAIS.