JP2018515475A5 - - Google Patents

Download PDF

Info

Publication number
JP2018515475A5
JP2018515475A5 JP2017556738A JP2017556738A JP2018515475A5 JP 2018515475 A5 JP2018515475 A5 JP 2018515475A5 JP 2017556738 A JP2017556738 A JP 2017556738A JP 2017556738 A JP2017556738 A JP 2017556738A JP 2018515475 A5 JP2018515475 A5 JP 2018515475A5
Authority
JP
Japan
Prior art keywords
substituted
compound according
independently
hydrogen
case
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017556738A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018515475A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/029587 external-priority patent/WO2016176343A1/en
Publication of JP2018515475A publication Critical patent/JP2018515475A/ja
Publication of JP2018515475A5 publication Critical patent/JP2018515475A5/ja
Pending legal-status Critical Current

Links

JP2017556738A 2015-04-27 2016-04-27 代謝的にプログラムされた金属キレーターおよびその使用 Pending JP2018515475A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562153468P 2015-04-27 2015-04-27
US62/153,468 2015-04-27
PCT/US2016/029587 WO2016176343A1 (en) 2015-04-27 2016-04-27 Metabolically programmed metal chelators and uses thereof

Publications (2)

Publication Number Publication Date
JP2018515475A JP2018515475A (ja) 2018-06-14
JP2018515475A5 true JP2018515475A5 (enExample) 2019-07-18

Family

ID=57199470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017556738A Pending JP2018515475A (ja) 2015-04-27 2016-04-27 代謝的にプログラムされた金属キレーターおよびその使用

Country Status (10)

Country Link
US (1) US10570104B2 (enExample)
EP (1) EP3288557A4 (enExample)
JP (1) JP2018515475A (enExample)
KR (1) KR20170140306A (enExample)
CN (1) CN107708693A (enExample)
AU (1) AU2016255770A1 (enExample)
CA (1) CA2984250A1 (enExample)
HK (1) HK1250216A1 (enExample)
IL (1) IL255279A0 (enExample)
WO (1) WO2016176343A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111176B1 (ko) 2011-12-16 2020-05-15 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 4'-데스페리티오신 유사체의 용도
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CN112542306B (zh) * 2020-12-17 2022-12-30 华东理工大学 一种基于一价金属离子的强顺磁性材料、其制备方法及应用
CN112960780B (zh) * 2021-03-03 2023-02-03 龙江环保集团股份有限公司 一种生物膜载体的预处理方法及生物法污水处理工艺

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274207A (en) 1966-09-20 Processes for preparing thiazole carboxylic acids
US39132A (en) 1863-07-07 Improved clod-crusher and harrow
US3809754A (en) 1968-12-31 1974-05-07 Medial De Toledo & Cie Method of treating diseases of the mucous membrane using compounds of a thiazolidine carboxylic acid and pharmaceutical preparations thereof
US3882110A (en) 1969-06-11 1975-05-06 Roussel Uclaf Novel 2-alkyl-5-thiazole-carboxylic acid derivatives
DE2045818A1 (de) 1969-09-17 1971-04-08 Godo Shusei Kabushiki Kaisha, Tokio Aeruginoinsäure und Verfahren zu ihrer Herstellung
FR2062120A5 (enExample) 1969-10-10 1971-06-25 Messier Fa
FR2141526B1 (enExample) 1971-06-14 1975-05-30 Roussel Uclaf
DE2245560A1 (de) 1972-09-16 1974-03-21 Basf Ag Verfahren zur herstellung von 4alkoxycarbonyl-2-thiazolinen
AU528115B2 (en) 1978-04-08 1983-04-14 Santen Pharmaceutical Co. Ltd. Antihypertensive 4-thiazolidine/carboxylic acids
CS205217B1 (cs) 1979-04-05 1981-05-29 Zdenek Vitamvas Dozimetr ionizujícího záření
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
DE3002989A1 (de) 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels
ZA815129B (en) 1980-07-28 1982-07-28 Ciba Geigy Ag Thiazoline derivatives and processes for their manufacture
EP0045281B1 (de) 1980-07-28 1985-05-08 Ciba-Geigy Ag Thiazolinderivate und Verfahren zu ihrer Herstellung
JPS5772975A (en) 1980-10-24 1982-05-07 Kureha Chem Ind Co Ltd 2-substituted phenylthiazole derviative, and medicine for peptic ulcer containing said derivative as active component
US4367233A (en) 1981-10-02 1983-01-04 American Home Products Corporation Inhibitors of mammalian collagenase
JPS62501769A (ja) 1984-12-18 1987-07-16 デイビツト ラビン 細胞毒性アルデヒドとベニシラミンとの反応性成物を含有する抗腫瘍組成物及びその使用方法
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
HU200177B (en) 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
US4736060A (en) 1985-08-06 1988-04-05 Nippon Rikagakuyakuhin Co., Ltd. Method for optical resolution of DL-cysteine and (R,S)-1-(1-naphthyl) ethylamine
EP0214101A3 (de) 1985-09-03 1989-05-31 Ciba-Geigy Ag Verwendung von Eisen(III)-Chelatoren vom Typ Desferrioxamin B und Desferriferrithiocin zur Behandlung von Malaria
EP0214933A3 (de) 1985-09-03 1989-05-24 Ciba-Geigy Ag Kombinationspräparate zur Behandlung von Malaria
JPS62142168A (ja) 1985-10-16 1987-06-25 Mitsubishi Chem Ind Ltd チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤
DE3621540A1 (de) 1986-06-27 1988-01-07 Basf Ag Chinolinderivate, verfahren zu ihrer herstellung, diese enthaltende mikrobizide und ihre verwendung zur bekaempfung von bakterien und pilzen
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
DE3735757A1 (de) 1987-10-22 1989-05-03 Degussa Optisch aktive salze aus einem substituierten thiazolidin-4-carboxylat und 3-chlor-2-hydroxypropyltrimethylammonium, deren herstellung und verwendung
ATE98631T1 (de) 1988-01-20 1994-01-15 Ciba Geigy Ag Verfahren zur herstellung von komplexverbindungen.
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
GB8826035D0 (en) 1988-11-07 1988-12-14 Ici Plc Herbicidal compositions
US5182402A (en) 1988-11-07 1993-01-26 Imperial Chemical Industries Plc Herbicidal compositions
US5106992A (en) 1989-07-28 1992-04-21 E. R. Squibb & Sons, Inc. 3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
NL9001955A (nl) 1990-09-05 1992-04-01 Cedona Pharm Bv Nieuwe thiazolidinederivaten.
US5393777A (en) 1990-11-15 1995-02-28 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Deferration using anguibactin siderophore
SG86971A1 (en) 1990-11-30 2002-03-19 Teijin Ltd 2-arylthiazole derivatives and pharmaceutical composition thereof
DK1130017T3 (da) 1990-11-30 2005-10-10 Otsuka Pharma Co Ltd Azolderivater og deres anvendelse som superoxidradikalinhibitorer
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
FR2677021B1 (fr) 1991-05-31 1993-10-01 Upsa Laboratoires Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5840739A (en) * 1992-11-16 1998-11-24 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
WO1994011367A1 (en) 1992-11-16 1994-05-26 University Of Florida Research Foundation Inc. 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives
DE4301356A1 (de) 1993-01-20 1994-07-21 Basf Ag Verfahren zur Herstellung von 2-Alkyl-4-fluormethyl-thiazolcarbonsäure-alkylestern
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
FR2749583B1 (fr) 1996-06-07 1998-08-21 Lipha Nouveaux derives de thiazolidine -2,4- dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
US20020049316A1 (en) 1997-04-29 2002-04-25 Halbert Stacie Marie Protease inhibitors
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US6373912B1 (en) 1997-06-16 2002-04-16 Legerity, Inc. Phase-locked loop arrangement with fast lock mode
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
MA26618A1 (fr) 1998-04-09 2004-12-20 Smithkline Beecham Corp Composes et compositions pharmaceutiques pour le traitement du paludisme
US6147070A (en) 1998-06-05 2000-11-14 Facchini; Francesco Methods and compositions for controlling iron stores to treat and cure disease states
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
US6159983A (en) 1998-09-18 2000-12-12 University Of Florida Method and composition for treatment of inflammatory bowel disease
CN1585639A (zh) 1998-09-21 2005-02-23 佛罗里达大学研究基金会 抗疟疾制剂
US6251927B1 (en) 1999-04-20 2001-06-26 Medinox, Inc. Methods for treatment of sickle cell anemia
DE19948434A1 (de) 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
US7160855B2 (en) 2002-03-14 2007-01-09 Children's Hospital & Research Center At Oakland Enhancement of iron chelation therapy
WO2004017959A2 (en) 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20040044220A1 (en) 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
EP1667727B1 (en) 2003-09-09 2008-07-09 University of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
WO2005034949A1 (en) 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
CA2587558A1 (en) 2004-11-19 2006-05-26 Shiva Biomedical, Llc Methods of treating erythropoietin-resistance
PL1866296T3 (pl) * 2005-04-04 2017-05-31 University Of Florida Research Foundation, Inc. Polieterowe analogi desferritiocyny
US20080194518A1 (en) 2005-12-23 2008-08-14 MOOKERJEE Pradip Antimicrobial Compositions
CN101129381B (zh) 2006-08-25 2012-02-01 天津和美生物技术有限公司 含β-内酰胺类抗生素和离子螯合剂的抗生素复方
WO2008130395A2 (en) 2006-12-12 2008-10-30 University Of Florida Desferrithiocin analogue actinide decorporation agents
CA2680592C (en) 2007-03-15 2016-07-05 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues and uses thereof in treating pathological conditions
FR2922210A1 (fr) 2007-10-11 2009-04-17 Univ Louis Pasteur Etablisseme Nouveaux composes, preparation et utilisations
WO2009140215A2 (en) * 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
AU2009260414A1 (en) * 2008-05-30 2009-12-23 University Of Cincinnati Use of zinc chelators to inhibit biofilm formation
WO2010009120A2 (en) * 2008-07-14 2010-01-21 Ferrokin Biosciences, Inc. Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
CN102648189A (zh) * 2009-07-27 2012-08-22 费罗金生物科学股份有限公司 作为金属螯合剂的脱氮杂去铁硫辛聚醚类似物的前药
EP2470515A4 (en) 2009-08-25 2013-04-24 Univ Florida POLYETHER DESFERRITHIOCIN ANALOGUES AND USES THEREOF
CA2780756A1 (en) * 2009-11-23 2011-05-26 Prothera, Inc. Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions
CA2798082A1 (en) 2010-05-04 2011-11-10 Shire Llc Desazadesferrothiocin analogues as metal chelation agents
WO2012027794A2 (en) 2010-09-01 2012-03-08 The Mental Health Research Institute Of Victoria Method of treatment and agents useful for same
EP2787994A4 (en) 2011-12-09 2015-08-26 Ferrokin Biosciences Inc ORAL FORMULATIONS FOR TREATING METAL OVERLOAD
US20140323534A1 (en) 2011-12-16 2014-10-30 University Of Florida Research Foundation, Inc. Uses of 3'-desferrithiocin analogs
KR102111176B1 (ko) 2011-12-16 2020-05-15 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 4'-데스페리티오신 유사체의 용도
WO2014027355A2 (en) * 2012-08-15 2014-02-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cytotoxic titanium and vanadium complexes
WO2014134701A1 (en) 2013-03-07 2014-09-12 Kane Biotech Inc. Antimicrobial-antibiofilm compositions and methods of use thereof
EP3071201A4 (en) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof

Similar Documents

Publication Publication Date Title
JP2016074674A5 (enExample)
JP2017502006A5 (enExample)
JP2017500295A5 (enExample)
JP2017504595A5 (enExample)
JP2018515475A5 (enExample)
JP2019527682A5 (enExample)
JP2019034943A5 (enExample)
JP2015531773A5 (enExample)
JP2019094345A5 (enExample)
JP2020169171A5 (enExample)
JP2019524883A5 (enExample)
JP2018515434A5 (enExample)
JP2019531279A5 (enExample)
JP2016121196A5 (enExample)
JP2011219498A5 (enExample)
JP2006515858A5 (enExample)
JP2017537940A5 (enExample)
JP2020502047A5 (enExample)
JP2015535847A5 (enExample)
JP2009523841A5 (enExample)
JP2018501285A5 (enExample)
JP2016500107A5 (ja) グルタミナーゼ阻害剤およびその使用方法
JP2009524691A5 (enExample)
JP2018529650A5 (enExample)
JP2019519587A5 (enExample)